FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9462, 912 aa 1>>>pF1KB9462 912 - 912 aa - 912 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0466+/-0.000466; mu= 22.9917+/- 0.029 mean_var=80.9517+/-16.122, 0's: 0 Z-trim(110.8): 117 B-trim: 298 in 1/49 Lambda= 0.142548 statistics sampled from 19103 (19231) to 19103 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.225), width: 16 Scan time: 12.540 The best scores are: opt bits E(85289) XP_016866280 (OMIM: 604100) PREDICTED: metabotropi ( 912) 6193 1284.5 0 XP_016866279 (OMIM: 604100) PREDICTED: metabotropi ( 912) 6193 1284.5 0 NP_000832 (OMIM: 604100) metabotropic glutamate re ( 912) 6193 1284.5 0 NP_001243741 (OMIM: 604100) metabotropic glutamate ( 743) 5003 1039.6 0 NP_001243742 (OMIM: 604100) metabotropic glutamate ( 779) 5003 1039.7 0 XP_016866282 (OMIM: 604100) PREDICTED: metabotropi ( 779) 5003 1039.7 0 XP_016866281 (OMIM: 604100) PREDICTED: metabotropi ( 832) 4999 1038.9 0 XP_016867563 (OMIM: 601116) PREDICTED: metabotropi ( 908) 4727 983.0 0 XP_006716001 (OMIM: 601116) PREDICTED: metabotropi ( 908) 4727 983.0 0 XP_011514393 (OMIM: 601116) PREDICTED: metabotropi ( 908) 4727 983.0 0 NP_000836 (OMIM: 601116) metabotropic glutamate re ( 908) 4727 983.0 0 XP_011514394 (OMIM: 601116) PREDICTED: metabotropi ( 908) 4669 971.0 0 NP_001120795 (OMIM: 601116) metabotropic glutamate ( 908) 4669 971.0 0 NP_000835 (OMIM: 604101) metabotropic glutamate re ( 915) 4426 921.1 0 NP_870989 (OMIM: 604101) metabotropic glutamate re ( 922) 4388 913.3 0 NP_000834 (OMIM: 257270,604096) metabotropic gluta ( 877) 4201 874.8 0 NP_001269776 (OMIM: 604100) metabotropic glutamate ( 604) 4118 857.6 0 XP_011514396 (OMIM: 601116) PREDICTED: metabotropi ( 747) 3936 820.2 0 XP_016867565 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3777 787.5 0 XP_016867568 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3777 787.5 0 XP_016867566 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3777 787.5 0 XP_016867564 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3777 787.5 0 XP_016867567 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3777 787.5 0 XP_011514397 (OMIM: 601116) PREDICTED: metabotropi ( 714) 3776 787.3 0 XP_011514404 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3719 775.6 0 XP_011514403 (OMIM: 601116) PREDICTED: metabotropi ( 703) 3719 775.6 0 XP_016861762 (OMIM: 604101) PREDICTED: metabotropi ( 749) 3684 768.4 0 XP_016861761 (OMIM: 604101) PREDICTED: metabotropi ( 756) 3646 760.6 0 NP_001243738 (OMIM: 604100) metabotropic glutamate ( 796) 3549 740.7 6.8e-213 NP_001243740 (OMIM: 604100) metabotropic glutamate ( 865) 3549 740.7 7.2e-213 XP_011514405 (OMIM: 601116) PREDICTED: metabotropi ( 629) 3332 695.9 1.6e-199 XP_016867569 (OMIM: 601116) PREDICTED: metabotropi ( 629) 3332 695.9 1.6e-199 XP_011514410 (OMIM: 601116) PREDICTED: metabotropi ( 552) 2749 576.0 1.8e-163 XP_016861760 (OMIM: 604099) PREDICTED: metabotropi ( 872) 2506 526.2 2.7e-148 NP_000830 (OMIM: 604099) metabotropic glutamate re ( 872) 2506 526.2 2.7e-148 NP_000831 (OMIM: 601115) metabotropic glutamate re ( 879) 2499 524.8 7.4e-148 XP_016873116 (OMIM: 604102) PREDICTED: metabotropi (1180) 2154 453.9 2.1e-126 NP_000833 (OMIM: 604102) metabotropic glutamate re (1180) 2154 453.9 2.1e-126 NP_001137303 (OMIM: 604102) metabotropic glutamate (1212) 2154 453.9 2.1e-126 XP_011541094 (OMIM: 604102) PREDICTED: metabotropi (1212) 2154 453.9 2.1e-126 XP_006718891 (OMIM: 604102) PREDICTED: metabotropi (1212) 2154 453.9 2.1e-126 NP_001264994 (OMIM: 604473,614831) metabotropic gl ( 906) 2137 450.3 1.9e-125 NP_001264995 (OMIM: 604473,614831) metabotropic gl ( 906) 2137 450.3 1.9e-125 XP_016866275 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2137 450.3 1.9e-125 XP_016866274 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2137 450.3 1.9e-125 XP_016866276 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2137 450.3 1.9e-125 NP_001264996 (OMIM: 604473,614831) metabotropic gl ( 908) 2137 450.3 1.9e-125 NP_001264993 (OMIM: 604473,614831) metabotropic gl (1194) 2137 450.4 2.4e-125 XP_011534084 (OMIM: 604473,614831) PREDICTED: meta (1194) 2137 450.4 2.4e-125 XP_016866273 (OMIM: 604473,614831) PREDICTED: meta (1194) 2137 450.4 2.4e-125 >>XP_016866280 (OMIM: 604100) PREDICTED: metabotropic gl (912 aa) initn: 6193 init1: 6193 opt: 6193 Z-score: 6881.0 bits: 1284.5 E(85289): 0 Smith-Waterman score: 6193; 100.0% identity (100.0% similar) in 912 aa overlap (1-912:1-912) 10 20 30 40 50 60 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT 850 860 870 880 890 900 910 pF1KB9 KQTYVTYTNHAI :::::::::::: XP_016 KQTYVTYTNHAI 910 >>XP_016866279 (OMIM: 604100) PREDICTED: metabotropic gl (912 aa) initn: 6193 init1: 6193 opt: 6193 Z-score: 6881.0 bits: 1284.5 E(85289): 0 Smith-Waterman score: 6193; 100.0% identity (100.0% similar) in 912 aa overlap (1-912:1-912) 10 20 30 40 50 60 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT 850 860 870 880 890 900 910 pF1KB9 KQTYVTYTNHAI :::::::::::: XP_016 KQTYVTYTNHAI 910 >>NP_000832 (OMIM: 604100) metabotropic glutamate recept (912 aa) initn: 6193 init1: 6193 opt: 6193 Z-score: 6881.0 bits: 1284.5 E(85289): 0 Smith-Waterman score: 6193; 100.0% identity (100.0% similar) in 912 aa overlap (1-912:1-912) 10 20 30 40 50 60 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT 850 860 870 880 890 900 910 pF1KB9 KQTYVTYTNHAI :::::::::::: NP_000 KQTYVTYTNHAI 910 >>NP_001243741 (OMIM: 604100) metabotropic glutamate rec (743 aa) initn: 5003 init1: 5003 opt: 5003 Z-score: 5559.5 bits: 1039.6 E(85289): 0 Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 740 aa overlap (173-912:4-743) 150 160 170 180 190 200 pF1KB9 IITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSD :::::::::::::::::::::::::::::: NP_001 MSCKIPQISYASTAPDLSDNSRYDFFSRVVPSD 10 20 30 210 220 230 240 250 260 pF1KB9 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB9 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB9 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB9 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB9 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB9 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB9 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB9 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB9 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB9 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB9 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA 640 650 660 670 680 690 870 880 890 900 910 pF1KB9 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI 700 710 720 730 740 >>NP_001243742 (OMIM: 604100) metabotropic glutamate rec (779 aa) initn: 5003 init1: 5003 opt: 5003 Z-score: 5559.3 bits: 1039.7 E(85289): 0 Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 740 aa overlap (173-912:40-779) 150 160 170 180 190 200 pF1KB9 IITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSD :::::::::::::::::::::::::::::: NP_001 WASALPAWAPPGLPHRSLLTRLLSQHVKPAKIPQISYASTAPDLSDNSRYDFFSRVVPSD 10 20 30 40 50 60 210 220 230 240 250 260 pF1KB9 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA 70 80 90 100 110 120 270 280 290 300 310 320 pF1KB9 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL 130 140 150 160 170 180 330 340 350 360 370 380 pF1KB9 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG 190 200 210 220 230 240 390 400 410 420 430 440 pF1KB9 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD 250 260 270 280 290 300 450 460 470 480 490 500 pF1KB9 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR 310 320 330 340 350 360 510 520 530 540 550 560 pF1KB9 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY 370 380 390 400 410 420 570 580 590 600 610 620 pF1KB9 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG 430 440 450 460 470 480 630 640 650 660 670 680 pF1KB9 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE 490 500 510 520 530 540 690 700 710 720 730 740 pF1KB9 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG 550 560 570 580 590 600 750 760 770 780 790 800 pF1KB9 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI 610 620 630 640 650 660 810 820 830 840 850 860 pF1KB9 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA 670 680 690 700 710 720 870 880 890 900 910 pF1KB9 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI 730 740 750 760 770 >>XP_016866282 (OMIM: 604100) PREDICTED: metabotropic gl (779 aa) initn: 5003 init1: 5003 opt: 5003 Z-score: 5559.3 bits: 1039.7 E(85289): 0 Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 740 aa overlap (173-912:40-779) 150 160 170 180 190 200 pF1KB9 IITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSD :::::::::::::::::::::::::::::: XP_016 WASALPAWAPPGLPHRSLLTRLLSQHVKPAKIPQISYASTAPDLSDNSRYDFFSRVVPSD 10 20 30 40 50 60 210 220 230 240 250 260 pF1KB9 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA 70 80 90 100 110 120 270 280 290 300 310 320 pF1KB9 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL 130 140 150 160 170 180 330 340 350 360 370 380 pF1KB9 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG 190 200 210 220 230 240 390 400 410 420 430 440 pF1KB9 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD 250 260 270 280 290 300 450 460 470 480 490 500 pF1KB9 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR 310 320 330 340 350 360 510 520 530 540 550 560 pF1KB9 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY 370 380 390 400 410 420 570 580 590 600 610 620 pF1KB9 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG 430 440 450 460 470 480 630 640 650 660 670 680 pF1KB9 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE 490 500 510 520 530 540 690 700 710 720 730 740 pF1KB9 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG 550 560 570 580 590 600 750 760 770 780 790 800 pF1KB9 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI 610 620 630 640 650 660 810 820 830 840 850 860 pF1KB9 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA 670 680 690 700 710 720 870 880 890 900 910 pF1KB9 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI 730 740 750 760 770 >>XP_016866281 (OMIM: 604100) PREDICTED: metabotropic gl (832 aa) initn: 4999 init1: 4999 opt: 4999 Z-score: 5554.4 bits: 1038.9 E(85289): 0 Smith-Waterman score: 4999; 99.9% identity (100.0% similar) in 740 aa overlap (173-912:93-832) 150 160 170 180 190 200 pF1KB9 IITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSD .::::::::::::::::::::::::::::: XP_016 QTLPKLFPHDGAKRKKRTLRTSGPCFGGGGQIPQISYASTAPDLSDNSRYDFFSRVVPSD 70 80 90 100 110 120 210 220 230 240 250 260 pF1KB9 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKA 130 140 150 160 170 180 270 280 290 300 310 320 pF1KB9 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVL 190 200 210 220 230 240 330 340 350 360 370 380 pF1KB9 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKG 250 260 270 280 290 300 390 400 410 420 430 440 pF1KB9 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVD 310 320 330 340 350 360 450 460 470 480 490 500 pF1KB9 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLR 370 380 390 400 410 420 510 520 530 540 550 560 pF1KB9 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPY 430 440 450 460 470 480 570 580 590 600 610 620 pF1KB9 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG 490 500 510 520 530 540 630 640 650 660 670 680 pF1KB9 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE 550 560 570 580 590 600 690 700 710 720 730 740 pF1KB9 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARG 610 620 630 640 650 660 750 760 770 780 790 800 pF1KB9 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFI 670 680 690 700 710 720 810 820 830 840 850 860 pF1KB9 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKA 730 740 750 760 770 780 870 880 890 900 910 pF1KB9 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI 790 800 810 820 830 >>XP_016867563 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 4705 init1: 2853 opt: 4727 Z-score: 5251.6 bits: 983.0 E(85289): 0 Smith-Waterman score: 4727; 74.9% identity (90.0% similar) in 910 aa overlap (3-912:5-908) 10 20 30 40 50 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVH :::. : : .::. :. . . . ... . .:::.:::: :::::::: XP_016 MVCEGKRS-----ASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVH 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 GRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQ ..: .: ::::::::::::::::::.:.:.::.::::: :::::.::::::::::.:::: XP_016 AKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQIS ::::::::::::...:.:..: :::.:::... :::::..:::::::::::::::::::: XP_016 SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQIS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 YASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAF ::::::.::::.:::::::::: :.:::::::::: :: ::::::.::::.::::::::: XP_016 YASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 IQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAAR : ::: :::::::: ::::::. :::.:::.::::: ::::::.:::::::::.::::. XP_016 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 RANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRR . ::.:::.:.:::::::::::: . ::.::::::::::: :. :::::: :::: :::: XP_016 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 NIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGH :.:::::::.:: :::. :. :..::.::::. :::..::.:::::::::::::::.:.. XP_016 NVWFAEFWEENFGCKLGSHG-KRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAY 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 ALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIY ::: ::.::::: .::::::. .:: .:: ::: :::.: ::.::::::::::::::::. XP_016 ALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIF 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 QYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPC :::. : :.:::::: ::..:::..: :.: . : :.:::::.::::::::::.:: XP_016 QYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPC 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 CWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVG ::::: : ::.::::. .:. :: :.::. :::::. :::::::: :::::.:.:.:..: XP_016 CWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 IAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIF : :: ::..:::::::::::.:::::::::::.::::::. :::::: :: ::.::.: XP_016 IIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVF 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 LGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWF ::::: .::::::::::::.:::::::.::.::.::::::::.:::::::.::::. ::: XP_016 LGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 VVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVP :::: : ..:. .::::::. :::::::::::::::: ::::.::::::::::::::::: XP_016 VVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVP 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 ETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLY ::::::::::::::::::.:::::::::::.:::.:.::::::::::.:::::::::::: XP_016 ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLY 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 MPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPAL :::::::.::::::: :::::.:::::::::..:. :::: :::::.::::::.::. . XP_016 MPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTS 840 850 860 870 880 890 900 910 pF1KB9 ATKQTYVTYTNHAI .:: ::..:.::.: XP_016 STKTTYISYSNHSI 900 >>XP_006716001 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 4705 init1: 2853 opt: 4727 Z-score: 5251.6 bits: 983.0 E(85289): 0 Smith-Waterman score: 4727; 74.9% identity (90.0% similar) in 910 aa overlap (3-912:5-908) 10 20 30 40 50 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVH :::. : : .::. :. . . . ... . .:::.:::: :::::::: XP_006 MVCEGKRS-----ASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVH 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 GRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQ ..: .: ::::::::::::::::::.:.:.::.::::: :::::.::::::::::.:::: XP_006 AKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQIS ::::::::::::...:.:..: :::.:::... :::::..:::::::::::::::::::: XP_006 SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQIS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 YASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAF ::::::.::::.:::::::::: :.:::::::::: :: ::::::.::::.::::::::: XP_006 YASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 IQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAAR : ::: :::::::: ::::::. :::.:::.::::: ::::::.:::::::::.::::. XP_006 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 RANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRR . ::.:::.:.:::::::::::: . ::.::::::::::: :. :::::: :::: :::: XP_006 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 NIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGH :.:::::::.:: :::. :. :..::.::::. :::..::.:::::::::::::::.:.. XP_006 NVWFAEFWEENFGCKLGSHG-KRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAY 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 ALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIY ::: ::.::::: .::::::. .:: .:: ::: :::.: ::.::::::::::::::::. XP_006 ALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIF 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 QYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPC :::. : :.:::::: ::..:::..: :.: . : :.:::::.::::::::::.:: XP_006 QYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPC 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 CWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVG ::::: : ::.::::. .:. :: :.::. :::::. :::::::: :::::.:.:.:..: XP_006 CWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 IAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIF : :: ::..:::::::::::.:::::::::::.::::::. :::::: :: ::.::.: XP_006 IIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVF 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 LGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWF ::::: .::::::::::::.:::::::.::.::.::::::::.:::::::.::::. ::: XP_006 LGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 VVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVP :::: : ..:. .::::::. :::::::::::::::: ::::.::::::::::::::::: XP_006 VVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVP 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 ETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLY ::::::::::::::::::.:::::::::::.:::.:.::::::::::.:::::::::::: XP_006 ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLY 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 MPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPAL :::::::.::::::: :::::.:::::::::..:. :::: :::::.::::::.::. . XP_006 MPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTS 840 850 860 870 880 890 900 910 pF1KB9 ATKQTYVTYTNHAI .:: ::..:.::.: XP_006 STKTTYISYSNHSI 900 >>XP_011514393 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 4705 init1: 2853 opt: 4727 Z-score: 5251.6 bits: 983.0 E(85289): 0 Smith-Waterman score: 4727; 74.9% identity (90.0% similar) in 910 aa overlap (3-912:5-908) 10 20 30 40 50 pF1KB9 MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVH :::. : : .::. :. . . . ... . .:::.:::: :::::::: XP_011 MVCEGKRS-----ASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVH 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 GRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQ ..: .: ::::::::::::::::::.:.:.::.::::: :::::.::::::::::.:::: XP_011 AKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQIS ::::::::::::...:.:..: :::.:::... :::::..:::::::::::::::::::: XP_011 SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQIS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 YASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAF ::::::.::::.:::::::::: :.:::::::::: :: ::::::.::::.::::::::: XP_011 YASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 IQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAAR : ::: :::::::: ::::::. :::.:::.::::: ::::::.:::::::::.::::. XP_011 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 RANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRR . ::.:::.:.:::::::::::: . ::.::::::::::: :. :::::: :::: :::: XP_011 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 NIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGH :.:::::::.:: :::. :. :..::.::::. :::..::.:::::::::::::::.:.. XP_011 NVWFAEFWEENFGCKLGSHG-KRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAY 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 ALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIY ::: ::.::::: .::::::. .:: .:: ::: :::.: ::.::::::::::::::::. XP_011 ALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIF 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 QYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPC :::. : :.:::::: ::..:::..: :.: . : :.:::::.::::::::::.:: XP_011 QYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPC 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 CWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVG ::::: : ::.::::. .:. :: :.::. :::::. :::::::: :::::.:.:.:..: XP_011 CWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 IAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIF : :: ::..:::::::::::.:::::::::::.::::::. :::::: :: ::.::.: XP_011 IIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVF 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 LGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWF ::::: .::::::::::::.:::::::.::.::.::::::::.:::::::.::::. ::: XP_011 LGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 VVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVP :::: : ..:. .::::::. :::::::::::::::: ::::.::::::::::::::::: XP_011 VVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVP 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 ETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLY ::::::::::::::::::.:::::::::::.:::.:.::::::::::.:::::::::::: XP_011 ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLY 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 MPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPAL :::::::.::::::: :::::.:::::::::..:. :::: :::::.::::::.::. . XP_011 MPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTS 840 850 860 870 880 890 900 910 pF1KB9 ATKQTYVTYTNHAI .:: ::..:.::.: XP_011 STKTTYISYSNHSI 900 912 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:34:36 2016 done: Thu Nov 3 23:34:38 2016 Total Scan time: 12.540 Total Display time: 0.360 Function used was FASTA [36.3.4 Apr, 2011]