FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9468, 2144 aa 1>>>pF1KB9468 2144 - 2144 aa - 2144 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9379+/-0.00143; mu= 21.6072+/- 0.086 mean_var=68.6135+/-13.521, 0's: 0 Z-trim(98.2): 42 B-trim: 21 in 1/47 Lambda= 0.154835 statistics sampled from 5283 (5287) to 5283 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.487), E-opt: 0.2 (0.162), width: 16 Scan time: 4.320 The best scores are: opt bits E(32554) CCDS31066.1 HEATR1 gene_id:55127|Hs108|chr1 (2144) 13740 3079.8 0 >>CCDS31066.1 HEATR1 gene_id:55127|Hs108|chr1 (2144 aa) initn: 13740 init1: 13740 opt: 13740 Z-score: 16570.6 bits: 3079.8 E(32554): 0 Smith-Waterman score: 13740; 100.0% identity (100.0% similar) in 2144 aa overlap (1-2144:1-2144) 10 20 30 40 50 60 pF1KB9 MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMENTFVNSLASQIIKTLTKIPSLIKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMENTFVNSLASQIIKTLTKIPSLIKDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 LNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHQFVSLSTSGGKYQFLADSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHQFVSLSTSGGKYQFLADSD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 VCLLPFMVINNDDTESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLIGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VCLLPFMVINNDDTESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLIGVA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 NQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VAVEDSVFLVFSLKKFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VAVEDSVFLVFSLKKFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 DAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 SKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 VLQGVNGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAMVLHLTLGKYNEFSVSLLNEDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VLQGVNGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAMVLHLTLGKYNEFSVSLLNEDPK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 SLDIFIKAVHTTKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SLDIFIKAVHTTKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 SHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 GSYWQRVTLILELLQHKKKLRSPQILVPTLFNLLSRCLEPLPQEQGNMEYTKQLILSCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GSYWQRVTLILELLQHKKKLRSPQILVPTLFNLLSRCLEPLPQEQGNMEYTKQLILSCLL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 NICQKLSPDGGKIPKDILDEEKFNVELIVQCIRLSEMPQTHHHALLLLGTVAGIFPDKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NICQKLSPDGGKIPKDILDEEKFNVELIVQCIRLSEMPQTHHHALLLLGTVAGIFPDKVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 HNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKII 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 SVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWILLILLFEQYVTKTVLAAAYGEKDAIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWILLILLFEQYVTKTVLAAAYGEKDAIL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 EADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETIPKAVSFNKSESQEEMLQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETIPKAVSFNKSESQEEMLQVF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 NVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYISA 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 VAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNPLPSVRRKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNPLPSVRRKAL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 DLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKN 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 FGAENPDPFVPVLNTAVKLIAPERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FGAENPDPFVPVLNTAVKLIAPERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 LTTMKNTSELVSSEVYLLSALAALQKVVETLPHFISPYLEGILSQVIHLEKITSEMGSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LTTMKNTSELVSSEVYLLSALAALQKVVETLPHFISPYLEGILSQVIHLEKITSEMGSAS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 QANIRLTSLKKTLATTLAPRVLLPAIKKTYKQIEKNWKNHMGPFMSILQEHIGVMKKEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QANIRLTSLKKTLATTLAPRVLLPAIKKTYKQIEKNWKNHMGPFMSILQEHIGVMKKEEL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 TSHQSQLTAFFLEALDFRAQHSENDLEEVGKTENCIIDCLVAMVVKLSEVTFRPLFFKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TSHQSQLTAFFLEALDFRAQHSENDLEEVGKTENCIIDCLVAMVVKLSEVTFRPLFFKLF 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 DWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFD 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 SENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQER 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 VTKHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VTKHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYI 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 pF1KB9 VLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF :::::::::::::::::::::::::::::::::::::::::::: CCDS31 VLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF 2110 2120 2130 2140 2144 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:39:42 2016 done: Thu Nov 3 23:39:43 2016 Total Scan time: 4.320 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]