FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9473, 832 aa 1>>>pF1KB9473 832 - 832 aa - 832 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2519+/-0.000943; mu= 16.7348+/- 0.057 mean_var=84.4807+/-17.209, 0's: 0 Z-trim(107.3): 15 B-trim: 2 in 1/50 Lambda= 0.139539 statistics sampled from 9506 (9514) to 9506 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.292), width: 16 Scan time: 3.990 The best scores are: opt bits E(32554) CCDS77790.1 SIDT1 gene_id:54847|Hs108|chr3 ( 832) 5556 1128.7 0 CCDS2974.1 SIDT1 gene_id:54847|Hs108|chr3 ( 827) 5505 1118.4 0 CCDS31682.1 SIDT2 gene_id:51092|Hs108|chr11 ( 832) 2288 470.8 4.3e-132 >>CCDS77790.1 SIDT1 gene_id:54847|Hs108|chr3 (832 aa) initn: 5556 init1: 5556 opt: 5556 Z-score: 6040.5 bits: 1128.7 E(32554): 0 Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 832 aa overlap (1-832:1-832) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 790 800 810 820 830 >>CCDS2974.1 SIDT1 gene_id:54847|Hs108|chr3 (827 aa) initn: 4365 init1: 4365 opt: 5505 Z-score: 5985.0 bits: 1118.4 E(32554): 0 Smith-Waterman score: 5505; 99.4% identity (99.4% similar) in 832 aa overlap (1-832:1-827) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKID---- 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 -LGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 720 730 740 750 760 770 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 780 790 800 810 820 >>CCDS31682.1 SIDT2 gene_id:51092|Hs108|chr11 (832 aa) initn: 3066 init1: 1404 opt: 2288 Z-score: 2484.9 bits: 470.8 E(32554): 4.3e-132 Smith-Waterman score: 3155; 59.3% identity (81.3% similar) in 811 aa overlap (44-832:31-832) 20 30 40 50 60 70 pF1KB9 PWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLSTENIYSFNYTSQPD . :.:...: :: :::.::.: . CCDS31 MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB9 QVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSE .. .::: :: ... . :.: ::::.. :.:.::::...:..::.: ::.: :::: CCDS31 RTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPP 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB9 ATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTASPSQPQYFLYKF . ::. :...:::....:... :.: :... : :::. : :... .::::: :.: CCDS31 TKNESE--IQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEF 130 140 150 160 170 200 210 220 230 240 250 pF1KB9 PKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDF :. :::::.::.:. :.::::.:.:...:::::::.:: : :.::.::::::::.:.::: CCDS31 PEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDF 180 190 200 210 220 230 260 270 280 290 300 310 pF1KB9 PGEQFFVVFVIKPEDYACGGSF-FIQEKENQTWNL-QRKKNLEVTIVPSIKESVYVKSSL :...:.:: :.: :: :::::. : :.. . .:.:.: : . .. .::.. : CCDS31 PSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGML 240 250 260 270 280 290 320 330 340 350 360 pF1KB9 FSVFIFLSFYLGCLLVGFVHYLRFQRKS----IDGSFGSNDGSGNMVASHPIAASTP-EG : . ::::::: .:.. . : ..:. :: . . .. : : .:.: :: CCDS31 FCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFP--GSSPYEG 300 310 320 330 340 350 370 380 390 400 410 pF1KB9 SNYGTIDE-SSSSPGRQMSSSDG----GPPGQS----------DTDSSVEESDFDTMPDI :::.... :.:. : :.. : : :.: :. :::::.:.::. :: CCDS31 YNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDI 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 ESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVN .::::.::::..::..::.:::.:.. :::.:::::: ::::::::::.::::::::::: CCDS31 DSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVN 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 VTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDI ::::::::::::::::::: ::::::::::::..:::.:::::.:.:.: : ::: .:. CCDS31 VTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDL 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 FAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQ :.: ::::::::::::: ::::::.:::::::::::.:::::::::::::::::::::: CCDS31 CALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQ 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 TRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMG :::::::::::::: .:.::. .::::::::... ::..:: ::..:.: ::::.:::: CCDS31 KRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMG 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 RFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRP :.:.: ::::: :.:::::.::: :::.:::::::.::..:::.: .:::.:: CCDS31 RWKLDS-----GIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRP 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 RDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLS :::::.:.: :::::::.::::::::::.:.. .::.::: :.:.:. ::.::::.:: CCDS31 NDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLS 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 SWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPV .:. :::::::.::.:::::::::::::::::. :.: :::::::::::::.:.::.: : CCDS31 TWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYV 780 790 800 810 820 830 pF1KB9 F : CCDS31 F 832 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:43:13 2016 done: Thu Nov 3 23:43:14 2016 Total Scan time: 3.990 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]