FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9473, 832 aa 1>>>pF1KB9473 832 - 832 aa - 832 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0624+/-0.000376; mu= 17.8766+/- 0.024 mean_var=85.5029+/-17.477, 0's: 0 Z-trim(114.3): 18 B-trim: 0 in 0/51 Lambda= 0.138702 statistics sampled from 24117 (24134) to 24117 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.283), width: 16 Scan time: 11.600 The best scores are: opt bits E(85289) NP_001295279 (OMIM: 606816) SID1 transmembrane fam ( 832) 5556 1122.1 0 NP_001309223 (OMIM: 606816) SID1 transmembrane fam ( 833) 5544 1119.7 0 XP_011511241 (OMIM: 606816) PREDICTED: SID1 transm ( 828) 5507 1112.3 0 NP_060169 (OMIM: 606816) SID1 transmembrane family ( 827) 5505 1111.9 0 XP_011511243 (OMIM: 606816) PREDICTED: SID1 transm ( 794) 5161 1043.1 0 NP_001309226 (OMIM: 606816) SID1 transmembrane fam ( 681) 4539 918.6 0 XP_016862155 (OMIM: 606816) PREDICTED: SID1 transm ( 625) 4175 845.7 0 XP_016862156 (OMIM: 606816) PREDICTED: SID1 transm ( 585) 3902 791.1 0 NP_001309227 (OMIM: 606816) SID1 transmembrane fam ( 651) 3902 791.1 0 NP_001309225 (OMIM: 606816) SID1 transmembrane fam ( 770) 3899 790.5 0 XP_016862154 (OMIM: 606816) PREDICTED: SID1 transm ( 653) 3894 789.5 0 NP_001309224 (OMIM: 606816) SID1 transmembrane fam ( 804) 3894 789.5 0 NP_001309228 (OMIM: 606816) SID1 transmembrane fam ( 580) 3851 780.8 0 XP_016862153 (OMIM: 606816) PREDICTED: SID1 transm ( 804) 3851 780.9 0 XP_016862157 (OMIM: 606816) PREDICTED: SID1 transm ( 405) 2611 532.6 1.3e-150 NP_001309229 (OMIM: 606816) SID1 transmembrane fam ( 405) 2611 532.6 1.3e-150 >>NP_001295279 (OMIM: 606816) SID1 transmembrane family (832 aa) initn: 5556 init1: 5556 opt: 5556 Z-score: 6005.0 bits: 1122.1 E(85289): 0 Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 832 aa overlap (1-832:1-832) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 790 800 810 820 830 >>NP_001309223 (OMIM: 606816) SID1 transmembrane family (833 aa) initn: 5542 init1: 4387 opt: 5544 Z-score: 5992.0 bits: 1119.7 E(85289): 0 Smith-Waterman score: 5544; 99.9% identity (99.9% similar) in 833 aa overlap (1-832:1-833) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 -DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYML ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYML 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB9 GIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAE 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB9 SREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 790 800 810 820 830 >>XP_011511241 (OMIM: 606816) PREDICTED: SID1 transmembr (828 aa) initn: 5511 init1: 4356 opt: 5507 Z-score: 5952.0 bits: 1112.3 E(85289): 0 Smith-Waterman score: 5507; 99.4% identity (99.5% similar) in 832 aa overlap (1-832:1-828) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT ::::::::::::::::::::::::::::::::::::::::::::::::::::::: . XP_011 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKI----A 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 720 730 740 750 760 770 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 780 790 800 810 820 >>NP_060169 (OMIM: 606816) SID1 transmembrane family mem (827 aa) initn: 4365 init1: 4365 opt: 5505 Z-score: 5949.9 bits: 1111.9 E(85289): 0 Smith-Waterman score: 5505; 99.4% identity (99.4% similar) in 832 aa overlap (1-832:1-827) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKID---- 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 -LGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 720 730 740 750 760 770 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 780 790 800 810 820 >>XP_011511243 (OMIM: 606816) PREDICTED: SID1 transmembr (794 aa) initn: 5161 init1: 5161 opt: 5161 Z-score: 5578.1 bits: 1043.1 E(85289): 0 Smith-Waterman score: 5204; 95.4% identity (95.4% similar) in 832 aa overlap (1-832:1-794) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWE------ 730 740 750 760 770 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::: XP_011 --------------------------------VLLTLDDDLDVVRRDQIPVF 780 790 >>NP_001309226 (OMIM: 606816) SID1 transmembrane family (681 aa) initn: 4539 init1: 4539 opt: 4539 Z-score: 4906.5 bits: 918.6 E(85289): 0 Smith-Waterman score: 4539; 100.0% identity (100.0% similar) in 681 aa overlap (152-832:1-681) 130 140 150 160 170 180 pF1KB9 YQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTA :::::::::::::::::::::::::::::: NP_001 MAPLGAQYKLLVTKLKHFQLRTNVAFHFTA 10 20 30 190 200 210 220 230 240 pF1KB9 SPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMT 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB9 KKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPSI 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB9 KESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIAA 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB9 STPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRTK 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB9 MFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICYY 280 290 300 310 320 330 490 500 510 520 530 540 pF1KB9 NFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPKH 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB9 FGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASA 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB9 YSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDTD 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB9 LGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLGI 520 530 540 550 560 570 730 740 750 760 770 780 pF1KB9 FICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAESR 580 590 600 610 620 630 790 800 810 820 830 pF1KB9 EKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 640 650 660 670 680 >>XP_016862155 (OMIM: 606816) PREDICTED: SID1 transmembr (625 aa) initn: 4175 init1: 4175 opt: 4175 Z-score: 4513.4 bits: 845.7 E(85289): 0 Smith-Waterman score: 4175; 100.0% identity (100.0% similar) in 625 aa overlap (208-832:1-625) 180 190 200 210 220 230 pF1KB9 HFTASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVY :::::::::::::::::::::::::::::: XP_016 MAYPCSVVSVQNIMCPVYDLDHNVEFNGVY 10 20 30 240 250 260 270 280 290 pF1KB9 QSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTI 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB9 VPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASH 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB9 PIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNI 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB9 IRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQD 220 230 240 250 260 270 480 490 500 510 520 530 pF1KB9 ICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYG 280 290 300 310 320 330 540 550 560 570 580 590 pF1KB9 IPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDI 340 350 360 370 380 390 600 610 620 630 640 650 pF1KB9 NASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDV 400 410 420 430 440 450 660 670 680 690 700 710 pF1KB9 SDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASY 460 470 480 490 500 510 720 730 740 750 760 770 pF1KB9 MLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTP 520 530 540 550 560 570 780 790 800 810 820 830 pF1KB9 AESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 580 590 600 610 620 >>XP_016862156 (OMIM: 606816) PREDICTED: SID1 transmembr (585 aa) initn: 3902 init1: 3902 opt: 3902 Z-score: 4218.6 bits: 791.1 E(85289): 0 Smith-Waterman score: 3902; 99.8% identity (100.0% similar) in 585 aa overlap (248-832:1-585) 220 230 240 250 260 270 pF1KB9 QNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFI .::::::::::::::::::::::::::::: XP_016 MQKKDFPGEQFFVVFVIKPEDYACGGSFFI 10 20 30 280 290 300 310 320 330 pF1KB9 QEKENQTWNLQRKKNLEVTIVPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEKENQTWNLQRKKNLEVTIVPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQR 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB9 KSIDGSFGSNDGSGNMVASHPIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSIDGSFGSNDGSGNMVASHPIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTD 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB9 SSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYAL 160 170 180 190 200 210 460 470 480 490 500 510 pF1KB9 PVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLR 220 230 240 250 260 270 520 530 540 550 560 570 pF1KB9 RDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSF 280 290 300 310 320 330 580 590 600 610 620 630 pF1KB9 MYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHV 340 350 360 370 380 390 640 650 660 670 680 690 pF1KB9 LASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNL 400 410 420 430 440 450 700 710 720 730 740 750 pF1KB9 VNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAV 460 470 480 490 500 510 760 770 780 790 800 810 pF1KB9 MWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTL 520 530 540 550 560 570 820 830 pF1KB9 DDDLDVVRRDQIPVF ::::::::::::::: XP_016 DDDLDVVRRDQIPVF 580 >>NP_001309227 (OMIM: 606816) SID1 transmembrane family (651 aa) initn: 3902 init1: 3902 opt: 3902 Z-score: 4217.9 bits: 791.1 E(85289): 0 Smith-Waterman score: 3902; 99.8% identity (100.0% similar) in 585 aa overlap (248-832:67-651) 220 230 240 250 260 270 pF1KB9 QNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFI .::::::::::::::::::::::::::::: NP_001 IHVLLSQSRISWDFLPSTSFLPPIIRLLCLMQKKDFPGEQFFVVFVIKPEDYACGGSFFI 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB9 QEKENQTWNLQRKKNLEVTIVPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEKENQTWNLQRKKNLEVTIVPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQR 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB9 KSIDGSFGSNDGSGNMVASHPIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSIDGSFGSNDGSGNMVASHPIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTD 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB9 SSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYAL 220 230 240 250 260 270 460 470 480 490 500 510 pF1KB9 PVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLR 280 290 300 310 320 330 520 530 540 550 560 570 pF1KB9 RDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSF 340 350 360 370 380 390 580 590 600 610 620 630 pF1KB9 MYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHV 400 410 420 430 440 450 640 650 660 670 680 690 pF1KB9 LASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNL 460 470 480 490 500 510 700 710 720 730 740 750 pF1KB9 VNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAV 520 530 540 550 560 570 760 770 780 790 800 810 pF1KB9 MWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTL 580 590 600 610 620 630 820 830 pF1KB9 DDDLDVVRRDQIPVF ::::::::::::::: NP_001 DDDLDVVRRDQIPVF 640 650 >>NP_001309225 (OMIM: 606816) SID1 transmembrane family (770 aa) initn: 3899 init1: 3899 opt: 3899 Z-score: 4213.5 bits: 790.5 E(85289): 0 Smith-Waterman score: 5012; 92.5% identity (92.5% similar) in 832 aa overlap (1-832:1-770) 10 20 30 40 50 60 pF1KB9 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSM ::::::: NP_001 ASPSQPQ----------------------------------------------------- 250 260 270 280 290 300 pF1KB9 TKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------KKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPS 190 200 210 220 230 310 320 330 340 350 360 pF1KB9 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIA 240 250 260 270 280 290 370 380 390 400 410 420 pF1KB9 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRT 300 310 320 330 340 350 430 440 450 460 470 480 pF1KB9 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICY 360 370 380 390 400 410 490 500 510 520 530 540 pF1KB9 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPK 420 430 440 450 460 470 550 560 570 580 590 600 pF1KB9 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINAS 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB9 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDVSDT 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB9 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLG 600 610 620 630 640 650 730 740 750 760 770 780 pF1KB9 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAES 660 670 680 690 700 710 790 800 810 820 830 pF1KB9 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF 720 730 740 750 760 770 832 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:43:14 2016 done: Thu Nov 3 23:43:16 2016 Total Scan time: 11.600 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]