FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9475, 343 aa 1>>>pF1KB9475 343 - 343 aa - 343 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9063+/-0.000325; mu= 14.3880+/- 0.020 mean_var=95.0832+/-18.901, 0's: 0 Z-trim(117.0): 20 B-trim: 335 in 1/57 Lambda= 0.131529 statistics sampled from 28680 (28700) to 28680 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.337), width: 16 Scan time: 7.550 The best scores are: opt bits E(85289) XP_016865067 (OMIM: 609433) PREDICTED: BRCA1-A com ( 349) 2242 435.4 8.6e-122 XP_005265993 (OMIM: 609433) PREDICTED: BRCA1-A com ( 349) 2242 435.4 8.6e-122 XP_016865068 (OMIM: 609433) PREDICTED: BRCA1-A com ( 349) 2242 435.4 8.6e-122 XP_016865066 (OMIM: 609433) PREDICTED: BRCA1-A com ( 438) 2039 397.0 4.1e-110 XP_005265990 (OMIM: 609433) PREDICTED: BRCA1-A com ( 438) 2039 397.0 4.1e-110 XP_005265989 (OMIM: 609433) PREDICTED: BRCA1-A com ( 438) 2039 397.0 4.1e-110 XP_016865065 (OMIM: 609433) PREDICTED: BRCA1-A com ( 438) 2039 397.0 4.1e-110 NP_001304890 (OMIM: 609433) BRCA1-A complex subuni ( 553) 2037 396.7 6.3e-110 XP_005265992 (OMIM: 609433) PREDICTED: BRCA1-A com ( 416) 2032 395.6 9.8e-110 XP_006714937 (OMIM: 609433) PREDICTED: BRCA1-A com ( 416) 2032 395.6 9.8e-110 XP_005265991 (OMIM: 609433) PREDICTED: BRCA1-A com ( 416) 2032 395.6 9.8e-110 XP_016865064 (OMIM: 609433) PREDICTED: BRCA1-A com ( 620) 2032 395.8 1.3e-109 XP_016865063 (OMIM: 609433) PREDICTED: BRCA1-A com ( 641) 2032 395.8 1.4e-109 NP_001186226 (OMIM: 609433) BRCA1-A complex subuni ( 719) 2032 395.8 1.5e-109 NP_001186227 (OMIM: 609433) BRCA1-A complex subuni ( 719) 2032 395.8 1.5e-109 XP_005265987 (OMIM: 609433) PREDICTED: BRCA1-A com ( 719) 2032 395.8 1.5e-109 NP_057374 (OMIM: 609433) BRCA1-A complex subunit R ( 719) 2032 395.8 1.5e-109 XP_006714934 (OMIM: 609433) PREDICTED: BRCA1-A com ( 719) 2032 395.8 1.5e-109 XP_011532872 (OMIM: 609433) PREDICTED: BRCA1-A com ( 537) 853 172.0 2.7e-42 XP_011532870 (OMIM: 609433) PREDICTED: BRCA1-A com ( 572) 853 172.0 2.8e-42 >>XP_016865067 (OMIM: 609433) PREDICTED: BRCA1-A complex (349 aa) initn: 2252 init1: 1437 opt: 2242 Z-score: 2307.5 bits: 435.4 E(85289): 8.6e-122 Smith-Waterman score: 2242; 98.3% identity (98.3% similar) in 349 aa overlap (1-343:1-349) 10 20 30 40 50 60 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGKWQQ :::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGKWQQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT 250 260 270 280 290 300 300 310 320 330 340 pF1KB9 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 310 320 330 340 >>XP_005265993 (OMIM: 609433) PREDICTED: BRCA1-A complex (349 aa) initn: 2252 init1: 1437 opt: 2242 Z-score: 2307.5 bits: 435.4 E(85289): 8.6e-122 Smith-Waterman score: 2242; 98.3% identity (98.3% similar) in 349 aa overlap (1-343:1-349) 10 20 30 40 50 60 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGKWQQ :::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_005 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGKWQQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT 250 260 270 280 290 300 300 310 320 330 340 pF1KB9 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 310 320 330 340 >>XP_016865068 (OMIM: 609433) PREDICTED: BRCA1-A complex (349 aa) initn: 2252 init1: 1437 opt: 2242 Z-score: 2307.5 bits: 435.4 E(85289): 8.6e-122 Smith-Waterman score: 2242; 98.3% identity (98.3% similar) in 349 aa overlap (1-343:1-349) 10 20 30 40 50 60 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTA 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGKWQQ :::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 AQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGKWQQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQSSFT 250 260 270 280 290 300 300 310 320 330 340 pF1KB9 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 310 320 330 340 >>XP_016865066 (OMIM: 609433) PREDICTED: BRCA1-A complex (438 aa) initn: 2049 init1: 1234 opt: 2039 Z-score: 2098.0 bits: 397.0 E(85289): 4.1e-110 Smith-Waterman score: 2039; 97.8% identity (98.1% similar) in 322 aa overlap (28-343:117-438) 10 20 30 40 50 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTS ::.::::::::::::::::::::::::::: XP_016 LALKMSEQEAREVNSQEEEEEELLRKAIAESLNSSQGIVEETSEEGNSVPASQSVAALTS 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB9 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB9 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB9 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGK ::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGK 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB9 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS 330 340 350 360 370 380 300 310 320 330 340 pF1KB9 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 390 400 410 420 430 >>XP_005265990 (OMIM: 609433) PREDICTED: BRCA1-A complex (438 aa) initn: 2049 init1: 1234 opt: 2039 Z-score: 2098.0 bits: 397.0 E(85289): 4.1e-110 Smith-Waterman score: 2039; 97.8% identity (98.1% similar) in 322 aa overlap (28-343:117-438) 10 20 30 40 50 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTS ::.::::::::::::::::::::::::::: XP_005 LALKMSEQEAREVNSQEEEEEELLRKAIAESLNSSQGIVEETSEEGNSVPASQSVAALTS 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB9 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB9 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB9 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGK ::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_005 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGK 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB9 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS 330 340 350 360 370 380 300 310 320 330 340 pF1KB9 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 390 400 410 420 430 >>XP_005265989 (OMIM: 609433) PREDICTED: BRCA1-A complex (438 aa) initn: 2049 init1: 1234 opt: 2039 Z-score: 2098.0 bits: 397.0 E(85289): 4.1e-110 Smith-Waterman score: 2039; 97.8% identity (98.1% similar) in 322 aa overlap (28-343:117-438) 10 20 30 40 50 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTS ::.::::::::::::::::::::::::::: XP_005 LALKMSEQEAREVNSQEEEEEELLRKAIAESLNSSQGIVEETSEEGNSVPASQSVAALTS 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB9 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB9 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB9 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGK ::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_005 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGK 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB9 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS 330 340 350 360 370 380 300 310 320 330 340 pF1KB9 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 390 400 410 420 430 >>XP_016865065 (OMIM: 609433) PREDICTED: BRCA1-A complex (438 aa) initn: 2049 init1: 1234 opt: 2039 Z-score: 2098.0 bits: 397.0 E(85289): 4.1e-110 Smith-Waterman score: 2039; 97.8% identity (98.1% similar) in 322 aa overlap (28-343:117-438) 10 20 30 40 50 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTS ::.::::::::::::::::::::::::::: XP_016 LALKMSEQEAREVNSQEEEEEELLRKAIAESLNSSQGIVEETSEEGNSVPASQSVAALTS 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB9 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKED 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB9 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDS 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB9 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSGRACSTVEGK ::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 GTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRACSTVEGK 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB9 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAGCSREMQS 330 340 350 360 370 380 300 310 320 330 340 pF1KB9 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 390 400 410 420 430 >>NP_001304890 (OMIM: 609433) BRCA1-A complex subunit RA (553 aa) initn: 2039 init1: 1224 opt: 2037 Z-score: 2094.5 bits: 396.7 E(85289): 6.3e-110 Smith-Waterman score: 2037; 92.2% identity (95.1% similar) in 344 aa overlap (6-343:211-553) 10 20 30 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGI .... .:: . .. : :. .::::: NP_001 EPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQC-GKPQSSQGI 190 200 210 220 230 40 50 60 70 80 90 pF1KB9 VEETSEEGNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEETSEEGNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPG 240 250 260 270 280 290 100 110 120 130 140 150 pF1KB9 SRDILDGVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRDILDGVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCN 300 310 320 330 340 350 160 170 180 190 200 210 pF1KB9 GLMEEDTVLTRRQKEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLMEEDTVLTRRQKEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQL 360 370 380 390 400 410 220 230 240 250 260 pF1KB9 AKA------EGSGRACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSE ::: ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKADQGDGPEGSGRACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSE 420 430 440 450 460 470 270 280 290 300 310 320 pF1KB9 TGAFRVPSPGMEEAGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGAFRVPSPGMEEAGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGS 480 490 500 510 520 530 330 340 pF1KB9 RTRTKAGRGRRRKF :::::::::::::: NP_001 RTRTKAGRGRRRKF 540 550 >>XP_005265992 (OMIM: 609433) PREDICTED: BRCA1-A complex (416 aa) initn: 2259 init1: 1224 opt: 2032 Z-score: 2091.1 bits: 395.6 E(85289): 9.8e-110 Smith-Waterman score: 2032; 95.2% identity (97.0% similar) in 331 aa overlap (19-343:87-416) 10 20 30 40 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPA ....: : . .:::::::::::::::::: XP_005 ERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHG-QSSQGIVEETSEEGNSVPA 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB9 SQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMA 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB9 DKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQ 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB9 KEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSG :::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_005 KEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSG 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB9 RACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEE 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB9 AGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRK 360 370 380 390 400 410 pF1KB9 F : XP_005 F >-- initn: 278 init1: 234 opt: 234 Z-score: 247.2 bits: 54.4 E(85289): 5e-07 Smith-Waterman score: 234; 73.9% identity (89.1% similar) in 46 aa overlap (1-46:1-46) 10 20 30 40 50 60 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS ::::::::::::::::::::::::::::::. : :..::... . XP_005 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKNECGQGEQASEKNECISEDMGDEDKEERQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK XP_005 SRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVA 70 80 90 100 110 120 >>XP_006714937 (OMIM: 609433) PREDICTED: BRCA1-A complex (416 aa) initn: 2259 init1: 1224 opt: 2032 Z-score: 2091.1 bits: 395.6 E(85289): 9.8e-110 Smith-Waterman score: 2032; 95.2% identity (97.0% similar) in 331 aa overlap (19-343:87-416) 10 20 30 40 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPA ....: : . .:::::::::::::::::: XP_006 ERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHG-QSSQGIVEETSEEGNSVPA 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB9 SQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMA 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB9 DKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQ 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB9 KEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKA------EGSG :::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_006 KEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSG 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB9 RACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEE 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB9 AGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRK 360 370 380 390 400 410 pF1KB9 F : XP_006 F >-- initn: 278 init1: 234 opt: 234 Z-score: 247.2 bits: 54.4 E(85289): 5e-07 Smith-Waterman score: 234; 73.9% identity (89.1% similar) in 46 aa overlap (1-46:1-46) 10 20 30 40 50 60 pF1KB9 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKSSQGIVEETSEEGNSVPASQSVAALTSKRS ::::::::::::::::::::::::::::::. : :..::... . XP_006 MLPLPDLDLWPLDRLPSPIKRKPQTLGSLKNECGQGEQASEKNECISEDMGDEDKEERQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADKEVGNKEDAEK XP_006 SRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVA 70 80 90 100 110 120 343 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:44:24 2016 done: Thu Nov 3 23:44:25 2016 Total Scan time: 7.550 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]