FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9476, 349 aa 1>>>pF1KB9476 349 - 349 aa - 349 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0041+/-0.000808; mu= 12.8104+/- 0.049 mean_var=72.3242+/-14.258, 0's: 0 Z-trim(107.9): 20 B-trim: 39 in 1/52 Lambda= 0.150811 statistics sampled from 9853 (9867) to 9853 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.303), width: 16 Scan time: 2.210 The best scores are: opt bits E(32554) CCDS2849.1 TWF2 gene_id:11344|Hs108|chr3 ( 349) 2330 516.0 1.9e-146 CCDS31780.2 TWF1 gene_id:5756|Hs108|chr12 ( 350) 1615 360.4 1.3e-99 CCDS55818.1 TWF1 gene_id:5756|Hs108|chr12 ( 357) 1591 355.2 4.9e-98 >>CCDS2849.1 TWF2 gene_id:11344|Hs108|chr3 (349 aa) initn: 2330 init1: 2330 opt: 2330 Z-score: 2742.7 bits: 516.0 E(32554): 1.9e-146 Smith-Waterman score: 2330; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349) 10 20 30 40 50 60 pF1KB9 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG 250 260 270 280 290 300 310 320 330 340 pF1KB9 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS 310 320 330 340 >>CCDS31780.2 TWF1 gene_id:5756|Hs108|chr12 (350 aa) initn: 1607 init1: 1607 opt: 1615 Z-score: 1901.9 bits: 360.4 E(32554): 1.3e-99 Smith-Waterman score: 1615; 65.4% identity (91.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB9 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL :.:::::.:.:..::.::.:: :. ::.:. ::.::::.:. ..: ::.::: :::: CCDS31 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE :. .::::.:.:::::::::.::.:.:::::.: :: ::::::::::.:::::::::::: CCDS31 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF .:::::.:.:. ::.:.: : ..:::::.::.::.::.::::.:...:..:::::::.:: CCDS31 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVGVDTKHQTLQGVAF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL :.. :: .::..:.....::.:...:.. : : :..: :.. .::.:.:.:.::::::: CCDS31 PISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDSARYHFFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG :::.:::: :::.::::::::: :::.:::::::::::::. ::....... .:::: .: CCDS31 YKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIRKIEIDNG 250 260 270 280 290 300 310 320 330 340 pF1KB9 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS ::::.:::.:::::::: ::.:::::::.:::: .::::::.: CCDS31 DELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD 310 320 330 340 350 >>CCDS55818.1 TWF1 gene_id:5756|Hs108|chr12 (357 aa) initn: 1574 init1: 812 opt: 1591 Z-score: 1873.6 bits: 355.2 E(32554): 4.9e-98 Smith-Waterman score: 1591; 64.1% identity (89.2% similar) in 351 aa overlap (1-344:1-351) 10 20 30 40 50 60 pF1KB9 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL :.:::::.:.:..::.::.:: :. ::.:. ::.::::.:. ..: ::.::: :::: CCDS55 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE :. .::::.:.:::::::::.::.:.:::::.: :: ::::::::::.:::::::::::: CCDS55 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINE-------VKTEISVESKHQ .:::::.:.:. ::.:.: : ..:::::.::.::.::.::: :.:...:..::: CCDS55 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINESPEDHIGVQTDVGVDTKHQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDA ::::.:::.. :: .::..:.....::.:...:.. : : :..: :.. .::.:.:.:. CCDS55 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 ARYHFFLYKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAK ::::::::::.:::: :::.::::::::: :::.:::::::::::::. ::....... . CCDS55 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR 250 260 270 280 290 300 300 310 320 330 340 pF1KB9 KIEIGDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS :::: .: ::::.:::.:::::::: ::.:::::::.:::: .::::::.: CCDS55 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD 310 320 330 340 350 349 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:45:35 2016 done: Thu Nov 3 23:45:36 2016 Total Scan time: 2.210 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]