FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9481, 2215 aa 1>>>pF1KB9481 2215 - 2215 aa - 2215 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1176+/-0.00131; mu= 21.4739+/- 0.080 mean_var=94.2791+/-18.324, 0's: 0 Z-trim(102.2): 136 B-trim: 5 in 2/51 Lambda= 0.132089 statistics sampled from 6694 (6839) to 6694 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.21), width: 16 Scan time: 5.470 The best scores are: opt bits E(32554) CCDS44943.1 PTPRB gene_id:5787|Hs108|chr12 (2215) 14728 2818.9 0 CCDS44944.1 PTPRB gene_id:5787|Hs108|chr12 (1997) 13166 2521.2 0 CCDS55845.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 10626 2037.1 0 CCDS81713.1 PTPRB gene_id:5787|Hs108|chr12 (2127) 9436 1810.4 0 CCDS55846.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 6804 1308.8 0 CCDS7945.1 PTPRJ gene_id:5795|Hs108|chr11 (1337) 1159 233.0 7.2e-60 CCDS8674.1 PTPRO gene_id:5800|Hs108|chr12 (1188) 1046 211.4 2e-53 CCDS33110.1 PTPRH gene_id:5794|Hs108|chr19 (1115) 1041 210.4 3.6e-53 CCDS53754.1 PTPRO gene_id:5800|Hs108|chr12 ( 377) 1034 208.8 3.8e-53 CCDS44837.1 PTPRO gene_id:5800|Hs108|chr12 ( 405) 1003 202.9 2.4e-51 CCDS8675.1 PTPRO gene_id:5800|Hs108|chr12 (1216) 1003 203.2 5.9e-51 CCDS73501.1 PTPRQ gene_id:374462|Hs108|chr12 (2299) 992 201.3 4.2e-50 CCDS54321.1 PTPRH gene_id:5794|Hs108|chr19 ( 937) 977 198.2 1.5e-49 CCDS55288.1 PTPRD gene_id:5789|Hs108|chr9 (1502) 928 189.0 1.4e-46 CCDS6472.2 PTPRD gene_id:5789|Hs108|chr9 (1505) 928 189.0 1.4e-46 CCDS55290.1 PTPRD gene_id:5789|Hs108|chr9 (1506) 901 183.8 5e-45 CCDS490.2 PTPRF gene_id:5792|Hs108|chr1 (1898) 894 182.6 1.5e-44 CCDS489.2 PTPRF gene_id:5792|Hs108|chr1 (1907) 894 182.6 1.5e-44 CCDS12139.1 PTPRS gene_id:5802|Hs108|chr19 (1501) 887 181.2 3.2e-44 CCDS74265.1 PTPRS gene_id:5802|Hs108|chr19 (1505) 887 181.2 3.2e-44 CCDS75813.1 PTPRD gene_id:5789|Hs108|chr9 (1496) 857 175.4 1.7e-42 CCDS42874.1 PTPRT gene_id:11122|Hs108|chr20 (1441) 832 170.7 4.4e-41 CCDS68127.1 PTPRT gene_id:11122|Hs108|chr20 (1460) 832 170.7 4.4e-41 CCDS43786.1 PTPRD gene_id:5789|Hs108|chr9 (1912) 823 169.0 1.8e-40 CCDS13039.1 PTPRA gene_id:5786|Hs108|chr20 ( 793) 817 167.6 2e-40 CCDS12140.1 PTPRS gene_id:5802|Hs108|chr19 (1910) 816 167.7 4.5e-40 CCDS13038.1 PTPRA gene_id:5786|Hs108|chr20 ( 802) 810 166.3 5e-40 CCDS55289.1 PTPRD gene_id:5789|Hs108|chr9 (1505) 797 164.0 4.6e-39 CCDS56505.1 PTPRZ1 gene_id:5803|Hs108|chr7 (1448) 796 163.8 5.1e-39 CCDS11840.1 PTPRM gene_id:5797|Hs108|chr18 (1452) 795 163.6 5.8e-39 CCDS58613.1 PTPRM gene_id:5797|Hs108|chr18 (1465) 795 163.6 5.9e-39 CCDS75517.1 PTPRK gene_id:5796|Hs108|chr6 (1439) 789 162.5 1.3e-38 CCDS5137.1 PTPRK gene_id:5796|Hs108|chr6 (1440) 789 162.5 1.3e-38 CCDS1398.2 PTPRC gene_id:5788|Hs108|chr1 (1145) 787 162.0 1.4e-38 CCDS1397.2 PTPRC gene_id:5788|Hs108|chr1 (1306) 787 162.1 1.5e-38 CCDS47473.1 PTPRK gene_id:5796|Hs108|chr6 (1446) 769 158.7 1.8e-37 CCDS78179.1 PTPRK gene_id:5796|Hs108|chr6 (1462) 769 158.7 1.8e-37 CCDS45930.1 PTPRS gene_id:5802|Hs108|chr19 (1948) 764 157.8 4.4e-37 CCDS34740.1 PTPRZ1 gene_id:5803|Hs108|chr7 (2315) 762 157.5 6.6e-37 CCDS7657.1 PTPRE gene_id:5791|Hs108|chr10 ( 700) 744 153.7 2.7e-36 CCDS7658.1 PTPRE gene_id:5791|Hs108|chr10 ( 642) 731 151.2 1.4e-35 CCDS335.1 PTPRU gene_id:10076|Hs108|chr1 (1436) 712 147.8 3.3e-34 CCDS334.1 PTPRU gene_id:10076|Hs108|chr1 (1446) 712 147.8 3.4e-34 CCDS2895.1 PTPRG gene_id:5793|Hs108|chr3 (1445) 697 144.9 2.4e-33 CCDS44098.2 PTPRU gene_id:10076|Hs108|chr1 (1440) 690 143.6 6.1e-33 CCDS13430.1 PTPN1 gene_id:5770|Hs108|chr20 ( 435) 678 141.0 1.1e-32 CCDS53290.1 PTPRU gene_id:10076|Hs108|chr1 (1433) 684 142.5 1.3e-32 CCDS11864.1 PTPN2 gene_id:5771|Hs108|chr18 ( 353) 673 140.0 1.9e-32 CCDS11863.1 PTPN2 gene_id:5771|Hs108|chr18 ( 387) 673 140.0 2e-32 CCDS11865.1 PTPN2 gene_id:5771|Hs108|chr18 ( 415) 673 140.0 2.1e-32 >>CCDS44943.1 PTPRB gene_id:5787|Hs108|chr12 (2215 aa) initn: 14728 init1: 14728 opt: 14728 Z-score: 15159.8 bits: 2818.9 E(32554): 0 Smith-Waterman score: 14728; 99.9% identity (100.0% similar) in 2215 aa overlap (1-2215:1-2215) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: CCDS44 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH 2170 2180 2190 2200 2210 >>CCDS44944.1 PTPRB gene_id:5787|Hs108|chr12 (1997 aa) initn: 13166 init1: 13166 opt: 13166 Z-score: 13551.7 bits: 2521.2 E(32554): 0 Smith-Waterman score: 13166; 99.8% identity (100.0% similar) in 1980 aa overlap (236-2215:18-1997) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: CCDS44 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS44 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS44 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP 410 420 430 440 450 460 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 470 480 490 500 510 520 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 530 540 550 560 570 580 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 590 600 610 620 630 640 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 650 660 670 680 690 700 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 710 720 730 740 750 760 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 770 780 790 800 810 820 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 830 840 850 860 870 880 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 890 900 910 920 930 940 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY 950 960 970 980 990 1000 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 1010 1020 1030 1040 1050 1060 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1070 1080 1090 1100 1110 1120 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1130 1140 1150 1160 1170 1180 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1190 1200 1210 1220 1230 1240 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1250 1260 1270 1280 1290 1300 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1310 1320 1330 1340 1350 1360 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1370 1380 1390 1400 1410 1420 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1430 1440 1450 1460 1470 1480 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1490 1500 1510 1520 1530 1540 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1550 1560 1570 1580 1590 1600 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1610 1620 1630 1640 1650 1660 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1670 1680 1690 1700 1710 1720 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1730 1740 1750 1760 1770 1780 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1790 1800 1810 1820 1830 1840 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1850 1860 1870 1880 1890 1900 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1910 1920 1930 1940 1950 1960 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: CCDS44 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1970 1980 1990 >>CCDS55845.1 PTPRB gene_id:5787|Hs108|chr12 (1907 aa) initn: 10295 init1: 10295 opt: 10626 Z-score: 10936.1 bits: 2037.1 E(32554): 0 Smith-Waterman score: 12379; 95.3% identity (95.5% similar) in 1980 aa overlap (236-2215:18-1907) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: CCDS55 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS55 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS55 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::: CCDS55 LVPGRLYQVTVSCVSGELSAQKMAVGRTFP------------------------------ 350 360 370 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP CCDS55 ------------------------------------------------------------ 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 380 390 400 410 420 430 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 440 450 460 470 480 490 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 500 510 520 530 540 550 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 560 570 580 590 600 610 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 620 630 640 650 660 670 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 680 690 700 710 720 730 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 740 750 760 770 780 790 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 800 810 820 830 840 850 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY 860 870 880 890 900 910 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 920 930 940 950 960 970 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 980 990 1000 1010 1020 1030 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1040 1050 1060 1070 1080 1090 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1100 1110 1120 1130 1140 1150 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1160 1170 1180 1190 1200 1210 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1220 1230 1240 1250 1260 1270 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1280 1290 1300 1310 1320 1330 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1340 1350 1360 1370 1380 1390 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1400 1410 1420 1430 1440 1450 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1460 1470 1480 1490 1500 1510 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1520 1530 1540 1550 1560 1570 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1580 1590 1600 1610 1620 1630 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1640 1650 1660 1670 1680 1690 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1700 1710 1720 1730 1740 1750 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1760 1770 1780 1790 1800 1810 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1820 1830 1840 1850 1860 1870 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: CCDS55 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1880 1890 1900 >>CCDS81713.1 PTPRB gene_id:5787|Hs108|chr12 (2127 aa) initn: 8574 init1: 8574 opt: 9436 Z-score: 9709.8 bits: 1810.4 E(32554): 0 Smith-Waterman score: 13980; 95.9% identity (96.0% similar) in 2215 aa overlap (1-2215:1-2127) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: CCDS81 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG ::::::::::::::::::::: CCDS81 VTTVSGGISSRQVVVEGRTVP--------------------------------------- 850 860 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS ::::::::::: CCDS81 -------------------------------------------------DKVQGVSVSNS 870 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1480 1490 1500 1510 1520 1530 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1540 1550 1560 1570 1580 1590 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1600 1610 1620 1630 1640 1650 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1660 1670 1680 1690 1700 1710 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1720 1730 1740 1750 1760 1770 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1780 1790 1800 1810 1820 1830 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1840 1850 1860 1870 1880 1890 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1900 1910 1920 1930 1940 1950 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 1960 1970 1980 1990 2000 2010 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH 2080 2090 2100 2110 2120 >>CCDS55846.1 PTPRB gene_id:5787|Hs108|chr12 (1907 aa) initn: 6366 init1: 6366 opt: 6804 Z-score: 6999.9 bits: 1308.8 E(32554): 0 Smith-Waterman score: 12413; 95.3% identity (95.5% similar) in 1980 aa overlap (236-2215:18-1907) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: CCDS55 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS55 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS55 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP 410 420 430 440 450 460 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 470 480 490 500 510 520 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 530 540 550 560 570 580 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 590 600 610 620 630 640 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 650 660 670 680 690 700 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 710 720 730 740 750 760 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 770 780 790 800 810 820 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 830 840 850 860 870 880 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 890 900 910 920 930 940 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPA----------- 950 960 970 980 990 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT CCDS55 ------------------------------------------------------------ 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ ::::::::::::::::::::::::::::::::::::::::: CCDS55 -------------------AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1000 1010 1020 1030 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1040 1050 1060 1070 1080 1090 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1100 1110 1120 1130 1140 1150 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1160 1170 1180 1190 1200 1210 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1220 1230 1240 1250 1260 1270 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1280 1290 1300 1310 1320 1330 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1340 1350 1360 1370 1380 1390 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1400 1410 1420 1430 1440 1450 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1460 1470 1480 1490 1500 1510 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1520 1530 1540 1550 1560 1570 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1580 1590 1600 1610 1620 1630 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1640 1650 1660 1670 1680 1690 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1700 1710 1720 1730 1740 1750 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1760 1770 1780 1790 1800 1810 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1820 1830 1840 1850 1860 1870 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: CCDS55 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1880 1890 1900 >>CCDS7945.1 PTPRJ gene_id:5795|Hs108|chr11 (1337 aa) initn: 960 init1: 484 opt: 1159 Z-score: 1188.3 bits: 233.0 E(32554): 7.2e-60 Smith-Waterman score: 1594; 29.3% identity (58.2% similar) in 1286 aa overlap (952-2204:125-1325) 930 940 950 960 970 980 pF1KB9 PGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYE ...::.: . . ..: ..:. CCDS79 SLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTN----VILTWKSNDTAASEYK 100 110 120 130 140 150 990 1000 1010 1020 1030 pF1KB9 VTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQ-GNGRTI---- ..:.: . .: .. . . : .. : :. : ..: : :: :. :.: CCDS79 YVVKHKMENEKTITVVH-QPWCNITGLRPATSYVFSITPGIG----NETWGDPRVIKVIT 160 170 180 190 200 1040 1050 1060 1070 1080 1090 pF1KB9 -PEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTS : ::.:: . ... ..::..:: .. ..:.... . .. . ... CCDS79 EPIPVSDLRVALTGVRKAALSWSNGNGTAS---CRVLLESIGSHEELTQ-DSRLQVNISG 210 220 230 240 250 260 1100 1110 1120 1130 1140 1150 pF1KB9 LTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDS : :: ::.: .... .. . : ..: . : : . . :. : :: CCDS79 LKPGVQYNINPYLLQSNKTKGDPL-GTEGGLDASNTERSRAG-SPTAPVHDESLVGPVDP 270 280 290 300 310 1160 1170 1180 1190 1200 1210 pF1KB9 YTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIAS--VSGSLKNQINVVGRTVP . .:. :.... . :: : .:. . : ..:. . . :: CCDS79 SS-----GQQSRDTEVL--------LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNA 320 330 340 350 360 1220 1230 1240 1250 1260 1270 pF1KB9 ASVQGVIADNAYSSYSLIVSWQ---KAAGVAERYDILLLTENGILLRNTSEPATTKQHKF .: : : : :. :: . :. . .. : : . :. :.::: .. . CCDS79 IQVFDVTAVNI-SATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV----I 370 380 390 400 410 420 1280 1290 1300 1310 1320 1330 pF1KB9 EDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGEL : . :.: . : : . . . . .: :. :.:.:.: :: .... :.. ..: CCDS79 PGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAES 430 440 450 460 470 480 1340 1350 1360 1370 1380 pF1KB9 SWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTH--SGELSNESFIFGR ..: . .: . :... ::. . .:. : : . :: . .: . . .: CCDS79 FQMHI---TQEGAGNSRVEITT-NQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNR 490 500 510 520 530 1390 1400 1410 1420 1430 1440 pF1KB9 TVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF-YELILYNPNGTKKENWKDKDLTEWRF :::..: .. .::. .:..:. .: .. :.:.. . .:... . :: .: . CCDS79 TVPSAVFDIHVVYVTTTE-MWLDWKSPDGASEYVYHLVIESKHGSNHTSTYDKAIT---L 540 550 560 570 580 590 1450 1460 1470 1480 1490 1500 pF1KB9 QGLVPGRKYVLWVVTHSGDLSNKVTAESRTAP-SPPSLMSFADIA-NTSLA-ITWKGPPD :::.:: .:. .: : .... . :: . :: .: :.. ::. : ..:.. : CCDS79 QGLIPG---TLYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDD 600 610 620 630 640 650 1510 1520 1530 1540 1550 1560 pF1KB9 WTDYNDFELQWLPRDALTVFNPYNNRKSEG---RIVYGLRPGRSYQFNVKTVSGDSWKTY . .. : : . : . : . . : : : :: :: .. . ::. :. CCDS79 ASPTYSYCL--LIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSL 660 670 680 690 700 1570 1580 1590 1600 1610 pF1KB9 SKPIFGSVRTKPDKIQNLHCR--PQNSTAIACSWIPPDSDFDGYSIECRK---MDTQEVE .: : : : .. .. :. :.. :.. .: : . :. .: . .. ..: CCDS79 -EPGRKSFCTDPASMASFDCEVVPKEP-ALVLKWTCPPGANAGFELEVSSGAWNNATHLE 710 720 730 740 750 760 1620 1630 1640 1650 1660 1670 pF1KB9 FSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVN . . . .. .: : .:: . : : . .... : : :::: .. CCDS79 SCSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNIT 770 780 790 800 810 820 1680 1690 1700 1710 1720 1730 pF1KB9 EKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHN .:..:.. :. : : ..: .: ..:.. . : :: . :.: .. CCDS79 S----VSHNSVK--VKFSGFEASHGPIKAYAVILTTG--------EAGHPSADVLKYTYE 830 840 850 860 870 1740 1750 1760 1770 1780 1790 pF1KB9 ASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYR . . .: . . .. :.:.. : :.. .:. . : . .: :.: .:: CCDS79 DFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEID-VGN--ESTTLGYYNGKLEPLGSYR 880 890 900 910 920 1800 1810 1820 1830 1840 1850 pF1KB9 ISIRAFTQLF----DEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLV . .::.. .. : . .. : . .: .. ..: :.: :. : .. .... CCDS79 ACVAGFTNITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDP--GVICGAVFGCIFGALVI 930 940 950 960 970 980 1860 1870 1880 1890 1900 1910 pF1KB9 AVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMK ..:. .: .: . .. . ..:. . .: : : :....::..: : CCDS79 VTVGGFIFWRK--KRKDAKNNEVSFSQIKP-------------KKSKLIRVENFEAYFKK 990 1000 1010 1020 1030 1920 1930 1940 1950 1960 1970 pF1KB9 LQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPC ::::: ...:::.:: :: .: : : ::::::::::.:::: .::::: :. CCDS79 QQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKLS-VQTHST 1040 1050 1060 1070 1080 1090 1980 1990 2000 2010 2020 2030 pF1KB9 SDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDH .:::::.:.:: . ....:.::::::.: :::.::::.::. :.:.:.:::.::.::.. CCDS79 DDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEE 1100 1110 1120 1130 1140 1150 2040 2050 2060 2070 2080 2090 pF1KB9 YWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP :::. : . :::. . : :: ::::::::.: . . . ..: : :.::.: ::::::: CCDS79 YWPSKQ-AQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPL-RQFHFTSWPDHGVP 1160 1170 1180 1190 1200 2100 2110 2120 2130 2140 2150 pF1KB9 ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYG .::. ::.: ::::...:: .: .:::::::::::::::.::.. :......::.:: CCDS79 DTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYG 1210 1220 1230 1240 1250 1260 2160 2170 2180 2190 2200 pF1KB9 AVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRS----EQENPLFPIYENVNPEYHR :.:::.:: ::::: :::.:.::: :..:..: . :.. . ::::. : CCDS79 IVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKVDLIYQNTTAMTIYENLAPVTTF 1270 1280 1290 1300 1310 1320 2210 pF1KB9 DPVYSRH CCDS79 GKTNGYIA 1330 >>CCDS8674.1 PTPRO gene_id:5800|Hs108|chr12 (1188 aa) initn: 970 init1: 582 opt: 1046 Z-score: 1072.7 bits: 211.4 E(32554): 2e-53 Smith-Waterman score: 1085; 30.4% identity (57.9% similar) in 856 aa overlap (1409-2203:349-1186) 1380 1390 1400 1410 1420 1430 pF1KB9 LSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWK :. .: .. :: ... . .. . CCDS86 MEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTA-FDGFHIHIEREENFTEYLMV 320 330 340 350 360 370 1440 1450 1460 1470 1480 pF1KB9 DKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPS------P----------- :.. :. . :: :: : :.: :.. : . : .:..: : : CCDS86 DEEAHEFVAELKEPG-KYKLSVTTFSSSGSCE-TRKSQSAKSLSFYISPSGEWIEELTEK 380 390 400 410 420 430 1490 1500 1510 1520 1530 pF1KB9 PSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLP------RDALTVFNPYNNRKSEGR :. .: ...:. ..: . . .::. .. . ... . . : .. . .. CCDS86 PQHVSVHVLSSTTALMSWTSSQE--NYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK 440 450 460 470 480 490 1540 1550 1560 1570 1580 1590 pF1KB9 -IVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWI :. .: :: .:: . .: : :. .. : :..: : . ::.. :: CCDS86 PIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAI--VPTGIKDLMLYPLGPTAVVLSWT 500 510 520 530 540 550 1600 1610 1620 1630 1640 pF1KB9 PPDSD-FDGYSIECRKMD--TQEVEFSRKLEKEKSL-----LNIMMLVPHKRYLVSIKVQ : : : .: .. :. :.. : .. . : :.: : . . CCDS86 RPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMV 560 570 580 590 600 610 1650 1660 1670 1680 1690 pF1KB9 SAGMTSEVVEDS-TITMIDRPPPPP-PHIRVNEKDVLISKSSINFTVNCS------WFSD . : :: ::..: : : .. .. . :: . . :.. : :. CCDS86 TWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVV 620 630 640 650 660 670 1700 1710 1720 1730 1740 1750 pF1KB9 TNGAVKYFTVVVREA-DGSDELKPEQQHPLP--SYLEYRHNASI-RVYQTNYFASKCAEN ..: : :.:.. . : : . . : . : :.:. :. . . : CCDS86 AEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFA 680 690 700 710 720 730 1760 1770 1780 1790 1800 pF1KB9 PNSNSKSFN---IKLGAE--MESLGGKCDPTQQKFCDGPLKPHTAYRISIRAF--TQLFD :... : . .. :. .: . . .:. . :. ... ..: .. . .. CCDS86 VNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAV-SSHVVTISSLLPATAYN 740 750 760 770 780 790 1810 1820 1830 1840 1850 1860 pF1KB9 EDLKEFTKPLYS-DTFFSLP-ITTESEPLFGAIEGVSA-GLFLIGMLVAVVALLICRQK- .. :.. : ::... ..:: .: .: .. . .:::.:. :.:.: :.: CCDS86 CSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLL--VTLIILRKKH 800 810 820 830 840 1870 1880 1890 1900 1910 pF1KB9 VSHGRERPSARL----SIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNY .. .:: .. . :..:: : . . . .:: . :.....:.... . ::.: CCDS86 LQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDY 850 860 870 880 890 900 1920 1930 1940 1950 1960 1970 pF1KB9 LLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINAS .: ..:::: .: . : :: :: ::::.:::::: .::.: ..... .:::::. CCDS86 KFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINAN 910 920 930 940 950 960 1980 1990 2000 2010 2020 2030 pF1KB9 YIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQD :::: : .:::.:::::: :..:::::: .:. . :::.::: :: ::::::::: .. CCDS86 YIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEE 970 980 990 1000 1010 1020 2040 2050 2060 2070 2080 2090 pF1KB9 SLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQS . :::. ..:.:: .:. :.:.: . : . . ::.::.::::::: ....: CCDS86 PIAYGDITVEMISEEEQDDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAES 1030 1040 1050 1060 1070 1080 2100 2110 2120 2130 2140 2150 pF1KB9 LIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDL ..:::. ::. ..: :: ..:::::::::::::::::.::.. ... ::: : : .. CCDS86 ILQFVHMVRQQATKSK--GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1090 1100 1110 1120 1130 1140 2160 2170 2180 2190 2200 2210 pF1KB9 RLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH : .:. ::::: ::...::::. . .: .: :::::. CCDS86 RSYRMSMVQTEEQYIFIHQCVQLMWMKKK---QQFCISDVIYENVSKS 1150 1160 1170 1180 >>CCDS33110.1 PTPRH gene_id:5794|Hs108|chr19 (1115 aa) initn: 1064 init1: 542 opt: 1041 Z-score: 1068.0 bits: 210.4 E(32554): 3.6e-53 Smith-Waterman score: 1171; 26.2% identity (55.6% similar) in 1200 aa overlap (1037-2202:30-1105) 1010 1020 1030 1040 1050 1060 pF1KB9 QLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTW---SGANGD :.: ..::.....: .. ..: .: ... CCDS33 MAGAGGGLGVWGNLVLLGLCSWTGARAPAPNPGRNLTVETQTTSSISLSWEVPDGLDSQ 10 20 30 40 50 1070 1080 1090 1100 1110 1120 pF1KB9 VDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSA-FIEGF ..: .: .: . . .:::. .: :: : : . . :..:. . CCDS33 NSNYWVQCT-GDGGTTETRN--TTATNVTVDGLGPGSLYTCSVWVEKDGVNSSVGTVTTA 60 70 80 90 100 110 1130 1140 1150 1160 1170 1180 pF1KB9 TVPSAVKNIHISPNGATDSLTVNW-TPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTF :.:. :.:... . ...:....: .: : : .. : .. .. . : . : CCDS33 TAPNPVRNLRVEAQ-TNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITV 120 130 140 150 160 170 1190 1200 1210 1220 1230 pF1KB9 HRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADN----AYSSYSLIVSWQKA :: : : . . : :: :: .: :.. . : : .. :. .::. CCDS33 DGLEPGCLYAFSMWV--G--KNGINSSRETRNATTAHNPVRNLRVEAQTTSSISLSWEVP 180 190 200 210 220 230 1240 1250 1260 1270 1280 1290 pF1KB9 AGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQT :. . . . .: :. .. .: . . : ::. : .. . . :. :. . CCDS33 DGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSVEIV 240 250 260 270 280 290 1300 1310 1320 1330 1340 1350 pF1KB9 EGRTVPAAVTDLRITENSTRHLSFRWTASEG---ELSWYNIFLYNPDGNLQERAQVDPLV . :.: : .: . ... ... : . .: . : :.. :. ::. :: . . CCDS33 TSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVE-YTGDGG---RAGTRSTA 300 310 320 330 340 1360 1370 1380 1390 1400 1410 pF1KB9 QS-FSFQNLLQGRMYKMVI-VTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNW .. .. . : : .: . . : ..: :.. . :.: : .:. . .:..:. . : CCDS33 HTNITVDRLEPGCLYVFSVWVGKNGINSSRETRNATTAPNPVRNLH-METQTNSSIALCW 350 360 370 380 390 400 1420 1430 1440 1450 1460 pF1KB9 SPASGDF--DFYELILYNPNG--TKKENWKDKDLTEWRFQGLVPGRKYVL--WVVTHSGD .: . :. . :. .: :. .: . ..: :.. :: :.. :. ..: CCDS33 EVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLE---PGTLYTFSVWA-EKNGA 410 420 430 440 450 460 1470 1480 1490 1500 1510 1520 pF1KB9 LSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGP--PDWTDYNDFELQWLPRDALTVF ... .. :.:. . .: : .:...:. : .: : ..:. . ..:. :...: CCDS33 RGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYS-YWVSWV-REGMT-- 470 480 490 500 510 1530 1540 1550 1560 1570 1580 pF1KB9 NPYNNRKSEGRIVYG-LRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRP .: .. : :. :. : :...: . .. . :.. . .. : :... .:. . CCDS33 DPRTQSTSGTDITLKELEAGSLYHLTVWAERNEV-RGYNSTL--TAATAPNEVTDLQNET 520 530 540 550 560 570 1590 1600 1610 1620 1630 1640 pF1KB9 QNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKR-YLVS :..... : : . ::.. :. CCDS33 QTKNSVMLWWKAPGD------------------------------------PHSQLYVYW 580 590 1650 1660 1670 1680 1690 1700 pF1KB9 IKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTN-- .. : : : : ::. :.. : .:.. CCDS33 VQWASKGHP-------------RRGQDPQANWVNQT----SRT------NETWYKVEALE 600 610 620 630 1710 1720 1730 1740 1750 pF1KB9 -GAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRV-YQTNYFASKCAENPNSN :.. ::: ... : .. . :. . .: . : .: . : : :... CCDS33 PGTLYNFTVWAERNDVASSTQSLCASTYPDTVTITSCVSTSAGYGVNLIWS-C---PQGG 640 650 660 670 680 690 1760 1770 1780 1790 1800 1810 pF1KB9 SKSFNIKLGAEMESLG-GKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPL ..:....:.. : ..: . . . :: . . : ..: ..: .: .. CCDS33 YEAFELEVGGQRGSQDRSSCGEAVSVLGLGPARSYPA------TITTIWD-GMKVVSH-- 700 710 720 730 740 1820 1830 1840 1850 1860 1870 pF1KB9 YSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSI :. ::: :.: :. .:..:. .::... ... :.. .. ...: : CCDS33 ------SVVCHTESA---GVIAGAFVGILLFLILVGLLIFFLKRRN-KKKQQKPELR--- 750 760 770 780 790 1880 1890 1900 1910 1920 1930 pF1KB9 RRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSC : ... :. : ..: : : . ::: .. ::..:. ::..:: CCDS33 --------DLVFSSPGD------IPAEDFADHVRKNERDSNCGFADEYQQLSLVGHSQSQ 800 810 820 830 1940 1950 1960 1970 1980 1990 pF1KB9 DIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPL .: :: .:::: :.:::: .:: :. . ..: :::::::..:: .:.:.::::: CCDS33 MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPL 840 850 860 870 880 890 2000 2010 2020 2030 2040 2050 pF1KB9 PGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLP : : :::..::::. :..::.:.:.: :::::.:::: :.. .: : . ...: :. CCDS33 PQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVME 900 910 920 930 940 950 2060 2070 2080 2090 2100 2110 pF1KB9 EWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGP .::.::. . :. . .:.::: .::::::: . ..:. : : .:...... .:: CCDS33 NWTVRELLLLQVEEQKTLS-VRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGP 960 970 980 990 1000 1010 2120 2130 2140 2150 2160 2170 pF1KB9 TVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQC .::::::::::::.:::: .:.::.:. . .. :. .: : ::::: :::.:::: CCDS33 PIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQC 1020 1030 1040 1050 1060 1070 2180 2190 2200 2210 pF1KB9 V-RDVLRARKLRSEQENPLFP----IYENVNPEYHRDPVYSRH . : . .. . .:.: : ::::: CCDS33 ILRFLQQSAQAPAEKEVPYEDVENLIYENVAAIQAHKLEV 1080 1090 1100 1110 >>CCDS53754.1 PTPRO gene_id:5800|Hs108|chr12 (377 aa) initn: 954 init1: 582 opt: 1034 Z-score: 1067.6 bits: 208.8 E(32554): 3.8e-53 Smith-Waterman score: 1034; 45.2% identity (72.3% similar) in 365 aa overlap (1846-2203:21-375) 1820 1830 1840 1850 1860 1870 pF1KB9 PLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQK-VSHGRERPSAR .:::.: .:.:.: :.: .. .:: .. CCDS53 MVTEMNPNVVVISVLAILSTLLIGLL--LVTLIILRKKHLQMARECGAGT 10 20 30 40 1880 1890 1900 1910 1920 1930 pF1KB9 L----SIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKD . :..:: : . . . .:: . :.....:.... . ::.: .: ..:::: CCDS53 FVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKL 50 60 70 80 90 100 1940 1950 1960 1970 1980 1990 pF1KB9 VGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREY .: . : :: :: ::::.:::::: .::.: ..... .:::::.:::: : .:: CCDS53 IGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEY 110 120 130 140 150 160 2000 2010 2020 2030 2040 2050 pF1KB9 IVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQM :.:::::: :..:::::: .:. . :::.::: :: ::::::::: .. . :::. ..: CCDS53 IATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEM 170 180 190 200 210 220 2060 2070 2080 2090 2100 pF1KB9 LSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDY .:: .:. :.:.: . : . . ::.::.::::::: ....:..:::. ::. CCDS53 ISEEEQDDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQ 230 240 250 260 270 280 2110 2120 2130 2140 2150 2160 pF1KB9 INRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTE ..: :: ..:::::::::::::::::.::.. ... ::: : : ..: .:. ::::: CCDS53 ATKSK--GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTE 290 300 310 320 330 340 2170 2180 2190 2200 2210 pF1KB9 CQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH ::...::::. . .: .: :::::. CCDS53 EQYIFIHQCVQLMWMKKK---QQFCISDVIYENVSKS 350 360 370 >>CCDS44837.1 PTPRO gene_id:5800|Hs108|chr12 (405 aa) initn: 943 init1: 571 opt: 1003 Z-score: 1035.2 bits: 202.9 E(32554): 2.4e-51 Smith-Waterman score: 1003; 46.8% identity (73.3% similar) in 329 aa overlap (1880-2203:83-403) 1850 1860 1870 1880 1890 1900 pF1KB9 MLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGN---RKTSCPIKINQF : :. ..: .:.. :: . :.....: CCDS44 ASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDF 60 70 80 90 100 110 1910 1920 1930 1940 1950 1960 pF1KB9 EGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSN .... . ::.: .: ..:::: .: . : :: :: ::::.:::::: .::.: . CCDS44 DAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVS 120 130 140 150 160 170 1970 1980 1990 2000 2010 2020 pF1KB9 VDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKG .... .:::::.:::: : .:::.:::::: :..:::::: .:. . :::.::: :: CCDS44 MNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKR 180 190 200 210 220 230 2030 2040 2050 2060 2070 2080 pF1KB9 RVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVW ::::::::: .. . :::. ..:.:: .:. :.:.: . : . . ::.::.: CCDS44 RVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---NYADEMQDVMHFNYTAW 240 250 260 270 280 2090 2100 2110 2120 2130 2140 pF1KB9 PDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDS :::::: ....:..:::. ::. ..: : : ..:::::::::::::::::.::.. . CCDS44 PDHGVPTANAAESILQFVHMVRQQATKSKG--PMIIHCSAGVGRTGTFIALDRLLQHIRD 290 300 310 320 330 340 2150 2160 2170 2180 2190 2200 pF1KB9 KDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNP .. ::: : : ..: .:. ::::: ::...::::. . .: .: :::::. CCDS44 HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK---QQFCISDVIYENVSK 350 360 370 380 390 400 2210 pF1KB9 EYHRDPVYSRH CCDS44 S 2215 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:22:42 2016 done: Sat Nov 5 21:22:43 2016 Total Scan time: 5.470 Total Display time: 1.210 Function used was FASTA [36.3.4 Apr, 2011]