FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9481, 2215 aa 1>>>pF1KB9481 2215 - 2215 aa - 2215 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9439+/-0.000504; mu= 22.7699+/- 0.032 mean_var=103.7553+/-20.392, 0's: 0 Z-trim(109.8): 498 B-trim: 397 in 1/58 Lambda= 0.125913 statistics sampled from 17490 (18037) to 17490 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.211), width: 16 Scan time: 21.540 The best scores are: opt bits E(85289) NP_001103224 (OMIM: 176882) receptor-type tyrosine (2215) 14728 2688.2 0 XP_006719591 (OMIM: 176882) PREDICTED: receptor-ty (2230) 14675 2678.6 0 NP_002828 (OMIM: 176882) receptor-type tyrosine-pr (1997) 13166 2404.5 0 XP_006719592 (OMIM: 176882) PREDICTED: receptor-ty (2012) 13113 2394.8 0 NP_001193900 (OMIM: 176882) receptor-type tyrosine (1907) 10626 1943.0 0 XP_016875213 (OMIM: 176882) PREDICTED: receptor-ty (1446) 9531 1744.0 0 NP_001317133 (OMIM: 176882) receptor-type tyrosine (2127) 9436 1726.9 0 XP_011536916 (OMIM: 176882) PREDICTED: receptor-ty (2142) 9383 1717.3 0 NP_001193901 (OMIM: 176882) receptor-type tyrosine (1907) 6804 1248.8 0 XP_016873574 (OMIM: 600925) PREDICTED: receptor-ty (1321) 1159 223.2 1.6e-56 NP_002834 (OMIM: 600925) receptor-type tyrosine-pr (1337) 1159 223.2 1.6e-56 XP_016873573 (OMIM: 600925) PREDICTED: receptor-ty (1344) 1159 223.2 1.6e-56 XP_016873572 (OMIM: 600925) PREDICTED: receptor-ty (1363) 1159 223.2 1.7e-56 XP_011525485 (OMIM: 602510) PREDICTED: receptor-ty (1122) 1051 203.5 1.2e-50 XP_016882545 (OMIM: 602510) PREDICTED: receptor-ty (1137) 1051 203.5 1.2e-50 NP_002839 (OMIM: 600579,614196) receptor-type tyro (1188) 1046 202.6 2.3e-50 NP_002833 (OMIM: 602510) receptor-type tyrosine-pr (1115) 1041 201.7 4e-50 XP_016882547 (OMIM: 602510) PREDICTED: receptor-ty (1130) 1041 201.7 4.1e-50 NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 1034 200.0 4.3e-50 NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 1034 200.0 4.3e-50 NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 1003 194.4 2.3e-48 NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 1003 194.4 2.3e-48 NP_109592 (OMIM: 600579,614196) receptor-type tyro (1216) 1003 194.8 5.2e-48 XP_016882550 (OMIM: 602510) PREDICTED: receptor-ty ( 959) 995 193.3 1.2e-47 XP_016882551 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 990 192.4 2.2e-47 XP_016882552 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 990 192.4 2.2e-47 XP_011525490 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 990 192.4 2.2e-47 NP_001138498 (OMIM: 603317,613391) phosphatidylino (2299) 992 193.1 3.3e-47 NP_001154912 (OMIM: 602510) receptor-type tyrosine ( 937) 977 190.0 1.1e-46 XP_016882548 (OMIM: 602510) PREDICTED: receptor-ty (1121) 973 189.3 2.1e-46 XP_016882549 (OMIM: 602510) PREDICTED: receptor-ty (1121) 944 184.1 8.2e-45 XP_016882546 (OMIM: 602510) PREDICTED: receptor-ty (1133) 939 183.2 1.5e-44 NP_001035802 (OMIM: 601598) receptor-type tyrosine (1502) 928 181.3 7.6e-44 XP_006716898 (OMIM: 601598) PREDICTED: receptor-ty (1502) 928 181.3 7.6e-44 XP_006716896 (OMIM: 601598) PREDICTED: receptor-ty (1505) 928 181.3 7.6e-44 NP_569075 (OMIM: 601598) receptor-type tyrosine-pr (1505) 928 181.3 7.6e-44 XP_006716902 (OMIM: 601598) PREDICTED: receptor-ty (1491) 922 180.2 1.6e-43 XP_006716901 (OMIM: 601598) PREDICTED: receptor-ty (1495) 922 180.2 1.6e-43 XP_016870484 (OMIM: 601598) PREDICTED: receptor-ty (1501) 922 180.2 1.6e-43 XP_016870481 (OMIM: 601598) PREDICTED: receptor-ty (1503) 907 177.5 1.1e-42 XP_016870479 (OMIM: 601598) PREDICTED: receptor-ty (1506) 907 177.5 1.1e-42 XP_016870478 (OMIM: 601598) PREDICTED: receptor-ty (1507) 904 176.9 1.6e-42 XP_016870480 (OMIM: 601598) PREDICTED: receptor-ty (1506) 901 176.4 2.3e-42 NP_569076 (OMIM: 601598) receptor-type tyrosine-pr (1506) 901 176.4 2.3e-42 XP_006716890 (OMIM: 601598) PREDICTED: receptor-ty (1893) 902 176.6 2.4e-42 XP_016874762 (OMIM: 603317,613391) PREDICTED: phos (2536) 903 176.9 2.6e-42 XP_016870468 (OMIM: 601598) PREDICTED: receptor-ty (1916) 895 175.4 5.8e-42 XP_005271139 (OMIM: 179590,616001) PREDICTED: rece (1796) 894 175.2 6.3e-42 XP_016857433 (OMIM: 179590,616001) PREDICTED: rece (1800) 894 175.2 6.3e-42 NP_569707 (OMIM: 179590,616001) receptor-type tyro (1898) 894 175.2 6.6e-42 >>NP_001103224 (OMIM: 176882) receptor-type tyrosine-pro (2215 aa) initn: 14728 init1: 14728 opt: 14728 Z-score: 14453.8 bits: 2688.2 E(85289): 0 Smith-Waterman score: 14728; 99.9% identity (100.0% similar) in 2215 aa overlap (1-2215:1-2215) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH 2170 2180 2190 2200 2210 >>XP_006719591 (OMIM: 176882) PREDICTED: receptor-type t (2230 aa) initn: 14675 init1: 14675 opt: 14675 Z-score: 14401.8 bits: 2678.6 E(85289): 0 Smith-Waterman score: 14675; 99.9% identity (100.0% similar) in 2208 aa overlap (1-2208:1-2208) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: XP_006 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRGGHLLHLLPQVS 2170 2180 2190 2200 2210 2220 XP_006 SSRYGQSGQA 2230 >>NP_002828 (OMIM: 176882) receptor-type tyrosine-protei (1997 aa) initn: 13166 init1: 13166 opt: 13166 Z-score: 12921.0 bits: 2404.5 E(85289): 0 Smith-Waterman score: 13166; 99.8% identity (100.0% similar) in 1980 aa overlap (236-2215:18-1997) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: NP_002 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_002 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_002 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP 410 420 430 440 450 460 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 470 480 490 500 510 520 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 530 540 550 560 570 580 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 590 600 610 620 630 640 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 650 660 670 680 690 700 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 710 720 730 740 750 760 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 770 780 790 800 810 820 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 830 840 850 860 870 880 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 890 900 910 920 930 940 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY 950 960 970 980 990 1000 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 1010 1020 1030 1040 1050 1060 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1070 1080 1090 1100 1110 1120 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1130 1140 1150 1160 1170 1180 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1190 1200 1210 1220 1230 1240 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1250 1260 1270 1280 1290 1300 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1310 1320 1330 1340 1350 1360 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1370 1380 1390 1400 1410 1420 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1430 1440 1450 1460 1470 1480 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1490 1500 1510 1520 1530 1540 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1550 1560 1570 1580 1590 1600 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1610 1620 1630 1640 1650 1660 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1670 1680 1690 1700 1710 1720 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1730 1740 1750 1760 1770 1780 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1790 1800 1810 1820 1830 1840 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1850 1860 1870 1880 1890 1900 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1910 1920 1930 1940 1950 1960 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: NP_002 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1970 1980 1990 >>XP_006719592 (OMIM: 176882) PREDICTED: receptor-type t (2012 aa) initn: 13113 init1: 13113 opt: 13113 Z-score: 12868.9 bits: 2394.8 E(85289): 0 Smith-Waterman score: 13113; 99.8% identity (100.0% similar) in 1973 aa overlap (236-2208:18-1990) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: XP_006 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_006 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_006 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP 410 420 430 440 450 460 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 470 480 490 500 510 520 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 530 540 550 560 570 580 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 590 600 610 620 630 640 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 650 660 670 680 690 700 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 710 720 730 740 750 760 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 770 780 790 800 810 820 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 830 840 850 860 870 880 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 890 900 910 920 930 940 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY 950 960 970 980 990 1000 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 1010 1020 1030 1040 1050 1060 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1070 1080 1090 1100 1110 1120 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1130 1140 1150 1160 1170 1180 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1190 1200 1210 1220 1230 1240 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1250 1260 1270 1280 1290 1300 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1310 1320 1330 1340 1350 1360 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1370 1380 1390 1400 1410 1420 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1430 1440 1450 1460 1470 1480 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1490 1500 1510 1520 1530 1540 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1550 1560 1570 1580 1590 1600 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1610 1620 1630 1640 1650 1660 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1670 1680 1690 1700 1710 1720 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1730 1740 1750 1760 1770 1780 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1790 1800 1810 1820 1830 1840 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1850 1860 1870 1880 1890 1900 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1910 1920 1930 1940 1950 1960 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH ::::::::::::::::::::::: XP_006 KLRSEQENPLFPIYENVNPEYHRGGHLLHLLPQVSSSRYGQSGQA 1970 1980 1990 2000 2010 >>NP_001193900 (OMIM: 176882) receptor-type tyrosine-pro (1907 aa) initn: 10295 init1: 10295 opt: 10626 Z-score: 10427.6 bits: 1943.0 E(85289): 0 Smith-Waterman score: 12379; 95.3% identity (95.5% similar) in 1980 aa overlap (236-2215:18-1907) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: NP_001 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::: NP_001 LVPGRLYQVTVSCVSGELSAQKMAVGRTFP------------------------------ 350 360 370 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP NP_001 ------------------------------------------------------------ 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 380 390 400 410 420 430 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 440 450 460 470 480 490 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 500 510 520 530 540 550 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 560 570 580 590 600 610 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 620 630 640 650 660 670 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 680 690 700 710 720 730 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 740 750 760 770 780 790 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 800 810 820 830 840 850 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY 860 870 880 890 900 910 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 920 930 940 950 960 970 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 980 990 1000 1010 1020 1030 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1040 1050 1060 1070 1080 1090 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1100 1110 1120 1130 1140 1150 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1160 1170 1180 1190 1200 1210 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1220 1230 1240 1250 1260 1270 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1280 1290 1300 1310 1320 1330 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1340 1350 1360 1370 1380 1390 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1400 1410 1420 1430 1440 1450 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1460 1470 1480 1490 1500 1510 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1520 1530 1540 1550 1560 1570 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1580 1590 1600 1610 1620 1630 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1640 1650 1660 1670 1680 1690 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1700 1710 1720 1730 1740 1750 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1760 1770 1780 1790 1800 1810 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1820 1830 1840 1850 1860 1870 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: NP_001 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1880 1890 1900 >>XP_016875213 (OMIM: 176882) PREDICTED: receptor-type t (1446 aa) initn: 9531 init1: 9531 opt: 9531 Z-score: 9354.2 bits: 1744.0 E(85289): 0 Smith-Waterman score: 9531; 100.0% identity (100.0% similar) in 1424 aa overlap (785-2208:1-1424) 760 770 780 790 800 810 pF1KB9 SISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVI :::::::::::::::::::::::::::::: XP_016 MTSSLFTNWTQAQGDVEFYQVLLIHENVVI 10 20 30 820 830 840 850 860 870 pF1KB9 KNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGR 40 50 60 70 80 90 880 890 900 910 920 930 pF1KB9 NDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRS 100 110 120 130 140 150 940 950 960 970 980 990 pF1KB9 GKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTK 160 170 180 190 200 210 1000 1010 1020 1030 1040 1050 pF1KB9 SIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLH 220 230 240 250 260 270 1060 1070 1080 1090 1100 1110 pF1KB9 VTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQ 280 290 300 310 320 330 1120 1130 1140 1150 1160 1170 pF1KB9 QSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPK 340 350 360 370 380 390 1180 1190 1200 1210 1220 1230 pF1KB9 HVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSW 400 410 420 430 440 450 1240 1250 1260 1270 1280 1290 pF1KB9 QKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKE 460 470 480 490 500 510 1300 1310 1320 1330 1340 1350 pF1KB9 AQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLV 520 530 540 550 560 570 1360 1370 1380 1390 1400 1410 pF1KB9 QSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSP 580 590 600 610 620 630 1420 1430 1440 1450 1460 1470 pF1KB9 ASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAE 640 650 660 670 680 690 1480 1490 1500 1510 1520 1530 pF1KB9 SRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEG 700 710 720 730 740 750 1540 1550 1560 1570 1580 1590 pF1KB9 RIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWI 760 770 780 790 800 810 1600 1610 1620 1630 1640 1650 pF1KB9 PPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEV 820 830 840 850 860 870 1660 1670 1680 1690 1700 1710 pF1KB9 VEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREAD 880 890 900 910 920 930 1720 1730 1740 1750 1760 1770 pF1KB9 GSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLG 940 950 960 970 980 990 1780 1790 1800 1810 1820 1830 pF1KB9 GKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPL 1000 1010 1020 1030 1040 1050 1840 1850 1860 1870 1880 1890 pF1KB9 FGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGN 1060 1070 1080 1090 1100 1110 1900 1910 1920 1930 1940 1950 pF1KB9 RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNI 1120 1130 1140 1150 1160 1170 1960 1970 1980 1990 2000 2010 pF1KB9 LPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVH 1180 1190 1200 1210 1220 1230 2020 2030 2040 2050 2060 2070 pF1KB9 NIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDA 1240 1250 1260 1270 1280 1290 2080 2090 2100 2110 2120 2130 pF1KB9 HRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIA 1300 1310 1320 1330 1340 1350 2140 2150 2160 2170 2180 2190 pF1KB9 LDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENP 1360 1370 1380 1390 1400 1410 2200 2210 pF1KB9 LFPIYENVNPEYHRDPVYSRH :::::::::::::: XP_016 LFPIYENVNPEYHRGGHLLHLLPQVSSSRYGQSGQA 1420 1430 1440 >>NP_001317133 (OMIM: 176882) receptor-type tyrosine-pro (2127 aa) initn: 8574 init1: 8574 opt: 9436 Z-score: 9258.7 bits: 1726.9 E(85289): 0 Smith-Waterman score: 13980; 95.9% identity (96.0% similar) in 2215 aa overlap (1-2215:1-2127) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG ::::::::::::::::::::: NP_001 VTTVSGGISSRQVVVEGRTVP--------------------------------------- 850 860 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS ::::::::::: NP_001 -------------------------------------------------DKVQGVSVSNS 870 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1480 1490 1500 1510 1520 1530 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1540 1550 1560 1570 1580 1590 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1600 1610 1620 1630 1640 1650 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1660 1670 1680 1690 1700 1710 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1720 1730 1740 1750 1760 1770 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1780 1790 1800 1810 1820 1830 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1840 1850 1860 1870 1880 1890 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1900 1910 1920 1930 1940 1950 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 1960 1970 1980 1990 2000 2010 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH 2080 2090 2100 2110 2120 >>XP_011536916 (OMIM: 176882) PREDICTED: receptor-type t (2142 aa) initn: 8521 init1: 8521 opt: 9383 Z-score: 9206.6 bits: 1717.3 E(85289): 0 Smith-Waterman score: 13927; 95.9% identity (96.0% similar) in 2208 aa overlap (1-2208:1-2120) 10 20 30 40 50 60 pF1KB9 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQWMWTEDEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQKQGSRVVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVRSTRNTAPPQILTTFNAVPDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 QDLQAGTIYNFKIISLDEERTVVLQTDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSY :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: XP_011 QDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG ::::::::::::::::::::: XP_011 VTTVSGGISSRQVVVEGRTVP--------------------------------------- 850 860 910 920 930 940 950 960 pF1KB9 KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNS ::::::::::: XP_011 -------------------------------------------------DKVQGVSVSNS 870 970 980 990 1000 1010 1020 pF1KB9 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB9 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB9 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KB9 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KB9 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTS 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KB9 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLS 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KB9 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELS 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KB9 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDK 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KB9 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWK 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KB9 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKT 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 1610 1620 pF1KB9 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRK 1480 1490 1500 1510 1520 1530 1630 1640 1650 1660 1670 1680 pF1KB9 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDV 1540 1550 1560 1570 1580 1590 1690 1700 1710 1720 1730 1740 pF1KB9 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIR 1600 1610 1620 1630 1640 1650 1750 1760 1770 1780 1790 1800 pF1KB9 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIR 1660 1670 1680 1690 1700 1710 1810 1820 1830 1840 1850 1860 pF1KB9 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLIC 1720 1730 1740 1750 1760 1770 1870 1880 1890 1900 1910 1920 pF1KB9 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYL 1780 1790 1800 1810 1820 1830 1930 1940 1950 1960 1970 1980 pF1KB9 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASY 1840 1850 1860 1870 1880 1890 1990 2000 2010 2020 2030 2040 pF1KB9 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS 1900 1910 1920 1930 1940 1950 2050 2060 2070 2080 2090 2100 pF1KB9 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQ 1960 1970 1980 1990 2000 2010 2110 2120 2130 2140 2150 2160 pF1KB9 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 pF1KB9 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRGGHLLHLLPQVS 2080 2090 2100 2110 2120 2130 XP_011 SSRYGQSGQA 2140 >>NP_001193901 (OMIM: 176882) receptor-type tyrosine-pro (1907 aa) initn: 6366 init1: 6366 opt: 6804 Z-score: 6675.4 bits: 1248.8 E(85289): 0 Smith-Waterman score: 12413; 95.3% identity (95.5% similar) in 1980 aa overlap (236-2215:18-1907) 210 220 230 240 250 260 pF1KB9 ERQHPNLHMTGITDTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRI .::::::::::::::::::::::::::::: NP_001 MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRI 10 20 30 40 270 280 290 300 310 320 pF1KB9 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQ ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 LGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQ 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB9 TDPLPPARFGVSKEKTTSTGLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNE 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB9 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSG 170 180 190 200 210 220 450 460 470 480 490 500 pF1KB9 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT 230 240 250 260 270 280 510 520 530 540 550 560 pF1KB9 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKE 290 300 310 320 330 340 570 580 590 600 610 620 pF1KB9 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQ 350 360 370 380 390 400 630 640 650 660 670 680 pF1KB9 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP 410 420 430 440 450 460 690 700 710 720 730 740 pF1KB9 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVP 470 480 490 500 510 520 750 760 770 780 790 800 pF1KB9 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV 530 540 550 560 570 580 810 820 830 840 850 860 pF1KB9 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVS 590 600 610 620 630 640 870 880 890 900 910 920 pF1KB9 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRL 650 660 670 680 690 700 930 940 950 960 970 980 pF1KB9 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIK 710 720 730 740 750 760 990 1000 1010 1020 1030 1040 pF1KB9 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTL 770 780 790 800 810 820 1050 1060 1070 1080 1090 1100 pF1KB9 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKIL 830 840 850 860 870 880 1110 1120 1130 1140 1150 1160 pF1KB9 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQ 890 900 910 920 930 940 1170 1180 1190 1200 1210 1220 pF1KB9 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAY ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPA----------- 950 960 970 980 990 1230 1240 1250 1260 1270 1280 pF1KB9 SSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILT NP_001 ------------------------------------------------------------ 1290 1300 1310 1320 1330 1340 pF1KB9 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ ::::::::::::::::::::::::::::::::::::::::: NP_001 -------------------AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1000 1010 1020 1030 1350 1360 1370 1380 1390 1400 pF1KB9 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTT 1040 1050 1060 1070 1080 1090 1410 1420 1430 1440 1450 1460 pF1KB9 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG 1100 1110 1120 1130 1140 1150 1470 1480 1490 1500 1510 1520 pF1KB9 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFN 1160 1170 1180 1190 1200 1210 1530 1540 1550 1560 1570 1580 pF1KB9 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQN 1220 1230 1240 1250 1260 1270 1590 1600 1610 1620 1630 1640 pF1KB9 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKV 1280 1290 1300 1310 1320 1330 1650 1660 1670 1680 1690 1700 pF1KB9 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKY 1340 1350 1360 1370 1380 1390 1710 1720 1730 1740 1750 1760 pF1KB9 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIK 1400 1410 1420 1430 1440 1450 1770 1780 1790 1800 1810 1820 pF1KB9 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSL 1460 1470 1480 1490 1500 1510 1830 1840 1850 1860 1870 1880 pF1KB9 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSV 1520 1530 1540 1550 1560 1570 1890 1900 1910 1920 1930 1940 pF1KB9 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPEN 1580 1590 1600 1610 1620 1630 1950 1960 1970 1980 1990 2000 pF1KB9 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFW 1640 1650 1660 1670 1680 1690 2010 2020 2030 2040 2050 2060 pF1KB9 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFK 1700 1710 1720 1730 1740 1750 2070 2080 2090 2100 2110 2120 pF1KB9 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAG 1760 1770 1780 1790 1800 1810 2130 2140 2150 2160 2170 2180 pF1KB9 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR 1820 1830 1840 1850 1860 1870 2190 2200 2210 pF1KB9 KLRSEQENPLFPIYENVNPEYHRDPVYSRH :::::::::::::::::::::::::::::: NP_001 KLRSEQENPLFPIYENVNPEYHRDPVYSRH 1880 1890 1900 >>XP_016873574 (OMIM: 600925) PREDICTED: receptor-type t (1321 aa) initn: 960 init1: 484 opt: 1159 Z-score: 1135.7 bits: 223.2 E(85289): 1.6e-56 Smith-Waterman score: 1594; 29.3% identity (58.2% similar) in 1286 aa overlap (952-2204:109-1309) 930 940 950 960 970 980 pF1KB9 PGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYE ...::.: . . ..: ..:. XP_016 SLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTN----VILTWKSNDTAASEYK 80 90 100 110 120 130 990 1000 1010 1020 1030 pF1KB9 VTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQ-GNGRTI---- ..:.: . .: .. . . : .. : :. : ..: : :: :. :.: XP_016 YVVKHKMENEKTITVVH-QPWCNITGLRPATSYVFSITPGIG----NETWGDPRVIKVIT 140 150 160 170 180 1040 1050 1060 1070 1080 1090 pF1KB9 -PEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTS : ::.:: . ... ..::..:: .. ..:.... . .. . ... XP_016 EPIPVSDLRVALTGVRKAALSWSNGNGTAS---CRVLLESIGSHEELTQ-DSRLQVNISG 190 200 210 220 230 240 1100 1110 1120 1130 1140 1150 pF1KB9 LTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDS : :: ::.: .... .. . : ..: . : : . . :. : :: XP_016 LKPGVQYNINPYLLQSNKTKGDPL-GTEGGLDASNTERSRAG-SPTAPVHDESLVGPVDP 250 260 270 280 290 300 1160 1170 1180 1190 1200 1210 pF1KB9 YTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIAS--VSGSLKNQINVVGRTVP . .:. :.... . :: : .:. . : ..:. . . :: XP_016 SS-----GQQSRDTEVL--------LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNA 310 320 330 340 350 1220 1230 1240 1250 1260 1270 pF1KB9 ASVQGVIADNAYSSYSLIVSWQ---KAAGVAERYDILLLTENGILLRNTSEPATTKQHKF .: : : : :. :: . :. . .. : : . :. :.::: .. . XP_016 IQVFDVTAVNI-SATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV----I 360 370 380 390 400 1280 1290 1300 1310 1320 1330 pF1KB9 EDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGEL : . :.: . : : . . . . .: :. :.:.:.: :: .... :.. ..: XP_016 PGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAES 410 420 430 440 450 460 1340 1350 1360 1370 1380 pF1KB9 SWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTH--SGELSNESFIFGR ..: . .: . :... ::. . .:. : : . :: . .: . . .: XP_016 FQMHI---TQEGAGNSRVEITT-NQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNR 470 480 490 500 510 520 1390 1400 1410 1420 1430 1440 pF1KB9 TVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF-YELILYNPNGTKKENWKDKDLTEWRF :::..: .. .::. .:..:. .: .. :.:.. . .:... . :: .: . XP_016 TVPSAVFDIHVVYVTTTE-MWLDWKSPDGASEYVYHLVIESKHGSNHTSTYDKAIT---L 530 540 550 560 570 1450 1460 1470 1480 1490 1500 pF1KB9 QGLVPGRKYVLWVVTHSGDLSNKVTAESRTAP-SPPSLMSFADIA-NTSLA-ITWKGPPD :::.:: .:. .: : .... . :: . :: .: :.. ::. : ..:.. : XP_016 QGLIPG---TLYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDD 580 590 600 610 620 630 1510 1520 1530 1540 1550 1560 pF1KB9 WTDYNDFELQWLPRDALTVFNPYNNRKSEG---RIVYGLRPGRSYQFNVKTVSGDSWKTY . .. : : . : . : . . : : : :: :: .. . ::. :. XP_016 ASPTYSYCL--LIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSL 640 650 660 670 680 690 1570 1580 1590 1600 1610 pF1KB9 SKPIFGSVRTKPDKIQNLHCR--PQNSTAIACSWIPPDSDFDGYSIECRK---MDTQEVE .: : : : .. .. :. :.. :.. .: : . :. .: . .. ..: XP_016 -EPGRKSFCTDPASMASFDCEVVPKEP-ALVLKWTCPPGANAGFELEVSSGAWNNATHLE 700 710 720 730 740 750 1620 1630 1640 1650 1660 1670 pF1KB9 FSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVN . . . .. .: : .:: . : : . .... : : :::: .. XP_016 SCSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNIT 760 770 780 790 800 810 1680 1690 1700 1710 1720 1730 pF1KB9 EKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHN .:..:.. :. : : ..: .: ..:.. . : :: . :.: .. XP_016 S----VSHNSVK--VKFSGFEASHGPIKAYAVILTTG--------EAGHPSADVLKYTYE 820 830 840 850 1740 1750 1760 1770 1780 1790 pF1KB9 ASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYR . . .: . . .. :.:.. : :.. .:. . : . .: :.: .:: XP_016 DFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEID-VGN--ESTTLGYYNGKLEPLGSYR 860 870 880 890 900 910 1800 1810 1820 1830 1840 1850 pF1KB9 ISIRAFTQLF----DEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLV . .::.. .. : . .. : . .: .. ..: :.: :. : .. .... XP_016 ACVAGFTNITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDP--GVICGAVFGCIFGALVI 920 930 940 950 960 970 1860 1870 1880 1890 1900 1910 pF1KB9 AVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMK ..:. .: .: . .. . ..:. . .: : : :....::..: : XP_016 VTVGGFIFWRK--KRKDAKNNEVSFSQIKP-------------KKSKLIRVENFEAYFKK 980 990 1000 1010 1920 1930 1940 1950 1960 1970 pF1KB9 LQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPC ::::: ...:::.:: :: .: : : ::::::::::.:::: .::::: :. XP_016 QQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKLS-VQTHST 1020 1030 1040 1050 1060 1070 1980 1990 2000 2010 2020 2030 pF1KB9 SDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDH .:::::.:.:: . ....:.::::::.: :::.::::.::. :.:.:.:::.::.::.. XP_016 DDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEE 1080 1090 1100 1110 1120 1130 2040 2050 2060 2070 2080 2090 pF1KB9 YWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP :::. : . :::. . : :: ::::::::.: . . . ..: : :.::.: ::::::: XP_016 YWPSKQ-AQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPL-RQFHFTSWPDHGVP 1140 1150 1160 1170 1180 1190 2100 2110 2120 2130 2140 2150 pF1KB9 ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYG .::. ::.: ::::...:: .: .:::::::::::::::.::.. :......::.:: XP_016 DTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYG 1200 1210 1220 1230 1240 1250 2160 2170 2180 2190 2200 pF1KB9 AVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRS----EQENPLFPIYENVNPEYHR :.:::.:: ::::: :::.:.::: :..:..: . :.. . ::::. : XP_016 IVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKVDLIYQNTTAMTIYENLAPVTTF 1260 1270 1280 1290 1300 1310 2210 pF1KB9 DPVYSRH XP_016 GKTNGYIA 1320 2215 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:22:44 2016 done: Sat Nov 5 21:22:47 2016 Total Scan time: 21.540 Total Display time: 1.950 Function used was FASTA [36.3.4 Apr, 2011]