FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9483, 857 aa 1>>>pF1KB9483 857 - 857 aa - 857 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6604+/-0.000505; mu= 5.9567+/- 0.032 mean_var=244.1507+/-48.869, 0's: 0 Z-trim(115.0): 29 B-trim: 0 in 0/56 Lambda= 0.082081 statistics sampled from 25202 (25230) to 25202 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.296), width: 16 Scan time: 11.010 The best scores are: opt bits E(85289) NP_036218 (OMIM: 604888) general transcription fac ( 886) 2809 347.1 2.1e-94 XP_005247022 (OMIM: 604888) PREDICTED: general tra ( 494) 2798 345.6 3.4e-94 NP_001193703 (OMIM: 604888) general transcription ( 413) 2620 324.4 6.7e-88 >>NP_036218 (OMIM: 604888) general transcription factor (886 aa) initn: 5574 init1: 2800 opt: 2809 Z-score: 1815.8 bits: 347.1 E(85289): 2.1e-94 Smith-Waterman score: 5520; 96.7% identity (96.7% similar) in 886 aa overlap (1-857:1-886) 10 20 30 40 50 60 pF1KB9 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM 370 380 390 400 410 420 430 440 450 pF1KB9 GDLYLDVAEAFLDV-----------------------------ECLKALGYMERAAESYG :::::::::::::: ::::::::::::::::: NP_036 GDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 KVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRS 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB9 TLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSN 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 DQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYD 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 DRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHR 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 FCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 FCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHM 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB9 ASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALEL 790 800 810 820 830 840 820 830 840 850 pF1KB9 PPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI :::::::::::::::::::::::::::::::::::::::::::::: NP_036 PPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI 850 860 870 880 >>XP_005247022 (OMIM: 604888) PREDICTED: general transcr (494 aa) initn: 3049 init1: 2788 opt: 2798 Z-score: 1812.0 bits: 345.6 E(85289): 3.4e-94 Smith-Waterman score: 2995; 94.1% identity (94.1% similar) in 494 aa overlap (393-857:1-494) 370 380 390 400 410 420 pF1KB9 EEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGD :::::::::::::::::::::::::::::: XP_005 MVCLVHLNILEPLNPLLTTLVEQNPEDMGD 10 20 30 430 440 450 pF1KB9 LYLDVAEAFLDV-----------------------------ECLKALGYMERAAESYGKV :::::::::::: ::::::::::::::::::: XP_005 LYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYGKV 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB9 VDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRSTL 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB9 LFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSNDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSNDQ 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB9 ESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYDDR 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB9 QKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHRFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHRFC 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB9 LRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMAS 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB9 QKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP 400 410 420 430 440 450 820 830 840 850 pF1KB9 LVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI :::::::::::::::::::::::::::::::::::::::::::: XP_005 LVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI 460 470 480 490 >>NP_001193703 (OMIM: 604888) general transcription fact (413 aa) initn: 2620 init1: 2620 opt: 2620 Z-score: 1699.1 bits: 324.4 E(85289): 6.7e-88 Smith-Waterman score: 2620; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KB9 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM :::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNVCNKICT 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 GDLYLDVAEAFLDVECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKA 857 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:50:08 2016 done: Thu Nov 3 23:50:10 2016 Total Scan time: 11.010 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]