FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9490, 1188 aa 1>>>pF1KB9490 1188 - 1188 aa - 1188 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9519+/-0.00112; mu= 15.4202+/- 0.067 mean_var=127.0435+/-25.506, 0's: 0 Z-trim(106.8): 25 B-trim: 80 in 1/50 Lambda= 0.113788 statistics sampled from 9171 (9183) to 9171 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.282), width: 16 Scan time: 3.890 The best scores are: opt bits E(32554) CCDS43384.1 FBXO38 gene_id:81545|Hs108|chr5 (1113) 5496 914.7 0 CCDS64285.1 FBXO38 gene_id:81545|Hs108|chr5 ( 943) 4330 723.2 7.1e-208 >>CCDS43384.1 FBXO38 gene_id:81545|Hs108|chr5 (1113 aa) initn: 7544 init1: 5496 opt: 5496 Z-score: 4879.0 bits: 914.7 E(32554): 0 Smith-Waterman score: 7398; 93.7% identity (93.7% similar) in 1188 aa overlap (1-1188:1-1113) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG ::::::::::::::::::::::::::::: CCDS43 PQESQRRTSRCSDEERPSTSRACVVNGPD------------------------------- 790 800 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :::::::::::::::: CCDS43 --------------------------------------------EVAKTKPRHAMKRKRT 810 820 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 830 840 850 860 870 880 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 890 900 910 920 930 940 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 950 960 970 980 990 1000 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1010 1020 1030 1040 1050 1060 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1070 1080 1090 1100 1110 >>CCDS64285.1 FBXO38 gene_id:81545|Hs108|chr5 (943 aa) initn: 4330 init1: 4330 opt: 4330 Z-score: 3845.5 bits: 723.2 E(32554): 7.1e-208 Smith-Waterman score: 5887; 79.4% identity (79.4% similar) in 1188 aa overlap (1-1188:1-943) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS ::::::::::::::::::::::::::::::::::::::: CCDS64 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELS--------------------- 610 620 630 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT CCDS64 ------------------------------------------------------------ 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR CCDS64 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG CCDS64 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :::::::::::::::: CCDS64 --------------------------------------------EVAKTKPRHAMKRKRT 640 650 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 660 670 680 690 700 710 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 720 730 740 750 760 770 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 780 790 800 810 820 830 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 840 850 860 870 880 890 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 900 910 920 930 940 1188 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:54:30 2016 done: Thu Nov 3 23:54:31 2016 Total Scan time: 3.890 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]