FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9490, 1188 aa 1>>>pF1KB9490 1188 - 1188 aa - 1188 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1519+/-0.000466; mu= 14.3471+/- 0.029 mean_var=136.6601+/-27.425, 0's: 0 Z-trim(114.3): 49 B-trim: 1061 in 1/50 Lambda= 0.109712 statistics sampled from 24092 (24140) to 24092 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.283), width: 16 Scan time: 15.030 The best scores are: opt bits E(85289) XP_005268570 (OMIM: 608533,615575) PREDICTED: F-bo (1188) 8059 1288.4 0 XP_006714860 (OMIM: 608533,615575) PREDICTED: F-bo (1146) 5717 917.7 0 XP_016865388 (OMIM: 608533,615575) PREDICTED: F-bo ( 822) 5571 894.5 0 NP_110420 (OMIM: 608533,615575) F-box only protein (1113) 5496 882.7 0 XP_011535986 (OMIM: 608533,615575) PREDICTED: F-bo ( 788) 5193 834.6 0 XP_016865389 (OMIM: 608533,615575) PREDICTED: F-bo ( 788) 5193 834.6 0 NP_001258652 (OMIM: 608533,615575) F-box only prot ( 943) 4330 698.1 6.9e-200 XP_016865390 (OMIM: 608533,615575) PREDICTED: F-bo ( 747) 3008 488.8 5.6e-137 XP_016865391 (OMIM: 608533,615575) PREDICTED: F-bo ( 713) 2630 428.9 5.5e-119 >>XP_005268570 (OMIM: 608533,615575) PREDICTED: F-box on (1188 aa) initn: 8059 init1: 8059 opt: 8059 Z-score: 6898.1 bits: 1288.4 E(85289): 0 Smith-Waterman score: 8059; 100.0% identity (100.0% similar) in 1188 aa overlap (1-1188:1-1188) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1150 1160 1170 1180 >>XP_006714860 (OMIM: 608533,615575) PREDICTED: F-box on (1146 aa) initn: 5717 init1: 5717 opt: 5717 Z-score: 4894.9 bits: 917.7 E(85289): 0 Smith-Waterman score: 7685; 96.5% identity (96.5% similar) in 1188 aa overlap (1-1188:1-1146) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :: :::::::::::::::: XP_006 AT------------------------------------------EVAKTKPRHAMKRKRT 850 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1100 1110 1120 1130 1140 >>XP_016865388 (OMIM: 608533,615575) PREDICTED: F-box on (822 aa) initn: 5571 init1: 5571 opt: 5571 Z-score: 4772.0 bits: 894.5 E(85289): 0 Smith-Waterman score: 5571; 100.0% identity (100.0% similar) in 822 aa overlap (367-1188:1-822) 340 350 360 370 380 390 pF1KB9 FSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVN :::::::::::::::::::::::::::::: XP_016 MANADLVKYGLADVVENPGIITDIGMKAVN 10 20 30 400 410 420 430 440 450 pF1KB9 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB9 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB9 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB9 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB9 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB9 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB9 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS 400 410 420 430 440 450 820 830 840 850 860 870 pF1KB9 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS 460 470 480 490 500 510 880 890 900 910 920 930 pF1KB9 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG 520 530 540 550 560 570 940 950 960 970 980 990 pF1KB9 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE 580 590 600 610 620 630 1000 1010 1020 1030 1040 1050 pF1KB9 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN 640 650 660 670 680 690 1060 1070 1080 1090 1100 1110 pF1KB9 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP 700 710 720 730 740 750 1120 1130 1140 1150 1160 1170 pF1KB9 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC 760 770 780 790 800 810 1180 pF1KB9 DVNGEPVEDDYI :::::::::::: XP_016 DVNGEPVEDDYI 820 >>NP_110420 (OMIM: 608533,615575) F-box only protein 38 (1113 aa) initn: 7544 init1: 5496 opt: 5496 Z-score: 4706.0 bits: 882.7 E(85289): 0 Smith-Waterman score: 7398; 93.7% identity (93.7% similar) in 1188 aa overlap (1-1188:1-1113) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG ::::::::::::::::::::::::::::: NP_110 PQESQRRTSRCSDEERPSTSRACVVNGPD------------------------------- 790 800 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :::::::::::::::: NP_110 --------------------------------------------EVAKTKPRHAMKRKRT 810 820 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 830 840 850 860 870 880 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 890 900 910 920 930 940 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 950 960 970 980 990 1000 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1010 1020 1030 1040 1050 1060 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: NP_110 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1070 1080 1090 1100 1110 >>XP_011535986 (OMIM: 608533,615575) PREDICTED: F-box on (788 aa) initn: 5193 init1: 5193 opt: 5193 Z-score: 4449.0 bits: 834.6 E(85289): 0 Smith-Waterman score: 5193; 99.7% identity (100.0% similar) in 769 aa overlap (420-1188:20-788) 390 400 410 420 430 440 pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI ..:::::::::::::::::::::::::::: XP_011 MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI 10 20 30 40 450 460 470 480 490 500 pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH 50 60 70 80 90 100 510 520 530 540 550 560 pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI 110 120 130 140 150 160 570 580 590 600 610 620 pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT 170 180 190 200 210 220 630 640 650 660 670 680 pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR 230 240 250 260 270 280 690 700 710 720 730 740 pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ 290 300 310 320 330 340 750 760 770 780 790 800 pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD 350 360 370 380 390 400 810 820 830 840 850 860 pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT 410 420 430 440 450 460 870 880 890 900 910 920 pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG 470 480 490 500 510 520 930 940 950 960 970 980 pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ 530 540 550 560 570 580 990 1000 1010 1020 1030 1040 pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM 590 600 610 620 630 640 1050 1060 1070 1080 1090 1100 pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR 650 660 670 680 690 700 1110 1120 1130 1140 1150 1160 pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV 710 720 730 740 750 760 1170 1180 pF1KB9 AIFIHYCDVNGEPVEDDYI ::::::::::::::::::: XP_011 AIFIHYCDVNGEPVEDDYI 770 780 >>XP_016865389 (OMIM: 608533,615575) PREDICTED: F-box on (788 aa) initn: 5193 init1: 5193 opt: 5193 Z-score: 4449.0 bits: 834.6 E(85289): 0 Smith-Waterman score: 5193; 99.7% identity (100.0% similar) in 769 aa overlap (420-1188:20-788) 390 400 410 420 430 440 pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI ..:::::::::::::::::::::::::::: XP_016 MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI 10 20 30 40 450 460 470 480 490 500 pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH 50 60 70 80 90 100 510 520 530 540 550 560 pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI 110 120 130 140 150 160 570 580 590 600 610 620 pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT 170 180 190 200 210 220 630 640 650 660 670 680 pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR 230 240 250 260 270 280 690 700 710 720 730 740 pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ 290 300 310 320 330 340 750 760 770 780 790 800 pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD 350 360 370 380 390 400 810 820 830 840 850 860 pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT 410 420 430 440 450 460 870 880 890 900 910 920 pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG 470 480 490 500 510 520 930 940 950 960 970 980 pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ 530 540 550 560 570 580 990 1000 1010 1020 1030 1040 pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM 590 600 610 620 630 640 1050 1060 1070 1080 1090 1100 pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR 650 660 670 680 690 700 1110 1120 1130 1140 1150 1160 pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV 710 720 730 740 750 760 1170 1180 pF1KB9 AIFIHYCDVNGEPVEDDYI ::::::::::::::::::: XP_016 AIFIHYCDVNGEPVEDDYI 770 780 >>NP_001258652 (OMIM: 608533,615575) F-box only protein (943 aa) initn: 4330 init1: 4330 opt: 4330 Z-score: 3709.6 bits: 698.1 E(85289): 6.9e-200 Smith-Waterman score: 5887; 79.4% identity (79.4% similar) in 1188 aa overlap (1-1188:1-943) 10 20 30 40 50 60 pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS ::::::::::::::::::::::::::::::::::::::: NP_001 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELS--------------------- 610 620 630 670 680 690 700 710 720 pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT NP_001 ------------------------------------------------------------ 730 740 750 760 770 780 pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR NP_001 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG NP_001 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT :::::::::::::::: NP_001 --------------------------------------------EVAKTKPRHAMKRKRT 640 650 910 920 930 940 950 960 pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 660 670 680 690 700 710 970 980 990 1000 1010 1020 pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 720 730 740 750 760 770 1030 1040 1050 1060 1070 1080 pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 780 790 800 810 820 830 1090 1100 1110 1120 1130 1140 pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 840 850 860 870 880 890 1150 1160 1170 1180 pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 900 910 920 930 940 >>XP_016865390 (OMIM: 608533,615575) PREDICTED: F-box on (747 aa) initn: 5056 init1: 3008 opt: 3008 Z-score: 2580.2 bits: 488.8 E(85289): 5.6e-137 Smith-Waterman score: 4910; 90.9% identity (90.9% similar) in 822 aa overlap (367-1188:1-747) 340 350 360 370 380 390 pF1KB9 FSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVN :::::::::::::::::::::::::::::: XP_016 MANADLVKYGLADVVENPGIITDIGMKAVN 10 20 30 400 410 420 430 440 450 pF1KB9 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB9 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB9 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB9 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB9 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB9 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB9 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD------- 400 410 420 430 440 820 830 840 850 860 870 pF1KB9 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS XP_016 ------------------------------------------------------------ 880 890 900 910 920 930 pF1KB9 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 --------EVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG 450 460 470 480 490 940 950 960 970 980 990 pF1KB9 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE 500 510 520 530 540 550 1000 1010 1020 1030 1040 1050 pF1KB9 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN 560 570 580 590 600 610 1060 1070 1080 1090 1100 1110 pF1KB9 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP 620 630 640 650 660 670 1120 1130 1140 1150 1160 1170 pF1KB9 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC 680 690 700 710 720 730 1180 pF1KB9 DVNGEPVEDDYI :::::::::::: XP_016 DVNGEPVEDDYI 740 >>XP_016865391 (OMIM: 608533,615575) PREDICTED: F-box on (713 aa) initn: 4678 init1: 2630 opt: 2630 Z-score: 2257.1 bits: 428.9 E(85289): 5.5e-119 Smith-Waterman score: 4532; 90.0% identity (90.2% similar) in 769 aa overlap (420-1188:20-713) 390 400 410 420 430 440 pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI ..:::::::::::::::::::::::::::: XP_016 MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI 10 20 30 40 450 460 470 480 490 500 pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH 50 60 70 80 90 100 510 520 530 540 550 560 pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI 110 120 130 140 150 160 570 580 590 600 610 620 pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT 170 180 190 200 210 220 630 640 650 660 670 680 pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR 230 240 250 260 270 280 690 700 710 720 730 740 pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ 290 300 310 320 330 340 750 760 770 780 790 800 pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD 350 360 370 380 390 400 810 820 830 840 850 860 pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT XP_016 ------------------------------------------------------------ 870 880 890 900 910 920 pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---------------EVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG 410 420 430 440 450 930 940 950 960 970 980 pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ 460 470 480 490 500 510 990 1000 1010 1020 1030 1040 pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM 520 530 540 550 560 570 1050 1060 1070 1080 1090 1100 pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR 580 590 600 610 620 630 1110 1120 1130 1140 1150 1160 pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV 640 650 660 670 680 690 1170 1180 pF1KB9 AIFIHYCDVNGEPVEDDYI ::::::::::::::::::: XP_016 AIFIHYCDVNGEPVEDDYI 700 710 1188 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:54:31 2016 done: Thu Nov 3 23:54:33 2016 Total Scan time: 15.030 Total Display time: 0.430 Function used was FASTA [36.3.4 Apr, 2011]