FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9492, 1203 aa 1>>>pF1KB9492 1203 - 1203 aa - 1203 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4693+/-0.00047; mu= 21.4528+/- 0.029 mean_var=67.9603+/-14.000, 0's: 0 Z-trim(107.7): 37 B-trim: 1019 in 1/56 Lambda= 0.155577 statistics sampled from 15712 (15730) to 15712 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.53), E-opt: 0.2 (0.184), width: 16 Scan time: 12.900 The best scores are: opt bits E(85289) XP_011533977 (OMIM: 615614) PREDICTED: protein MMS (1221) 7767 1753.5 0 XP_016866146 (OMIM: 615614) PREDICTED: protein MMS ( 960) 5244 1187.2 0 XP_006715493 (OMIM: 615614) PREDICTED: protein MMS (1243) 5244 1187.2 0 NP_940870 (OMIM: 615614) protein MMS22-like [Homo (1243) 5244 1187.2 0 XP_011533981 (OMIM: 615614) PREDICTED: protein MMS ( 858) 5080 1150.4 0 XP_011533980 (OMIM: 615614) PREDICTED: protein MMS ( 967) 5080 1150.4 0 XP_011533979 (OMIM: 615614) PREDICTED: protein MMS ( 978) 5080 1150.4 0 XP_011533978 (OMIM: 615614) PREDICTED: protein MMS (1035) 5080 1150.4 0 XP_016866145 (OMIM: 615614) PREDICTED: protein MMS (1035) 5080 1150.4 0 XP_011533972 (OMIM: 615614) PREDICTED: protein MMS (1261) 5080 1150.4 0 XP_011533975 (OMIM: 615614) PREDICTED: protein MMS (1261) 5080 1150.4 0 XP_011533973 (OMIM: 615614) PREDICTED: protein MMS (1261) 5080 1150.4 0 XP_011533974 (OMIM: 615614) PREDICTED: protein MMS (1261) 5080 1150.4 0 XP_011533976 (OMIM: 615614) PREDICTED: protein MMS (1261) 5080 1150.4 0 XP_011533982 (OMIM: 615614) PREDICTED: protein MMS ( 742) 4496 1019.2 0 XP_006715495 (OMIM: 615614) PREDICTED: protein MMS ( 680) 2687 613.2 1.8e-174 >>XP_011533977 (OMIM: 615614) PREDICTED: protein MMS22-l (1221 aa) initn: 7767 init1: 7767 opt: 7767 Z-score: 9411.6 bits: 1753.5 E(85289): 0 Smith-Waterman score: 7767; 99.4% identity (99.7% similar) in 1183 aa overlap (1-1183:1-1183) 10 20 30 40 50 60 pF1KB9 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQNSSFSISWLPFKGLANTMKSPLSMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQNSSFSISWLPFKGLANTMKSPLSMLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLM ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_011 EELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 YAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 SSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 FQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSI ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 VLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 SEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 LTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 YLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 PISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 LVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 TVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLEN :::::::::::::::::::::::::::::::::::: . . :: XP_011 TVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQSDRFRKLYISAVLLLLKTHFSVPH 1150 1160 1170 1180 1190 1200 pF1KB9 DNT XP_011 WEVDFIALDVLFFNKIYGGKS 1210 1220 >>XP_016866146 (OMIM: 615614) PREDICTED: protein MMS22-l (960 aa) initn: 6014 init1: 5244 opt: 5244 Z-score: 6352.7 bits: 1187.2 E(85289): 0 Smith-Waterman score: 5938; 95.6% identity (95.7% similar) in 960 aa overlap (284-1203:1-960) 260 270 280 290 300 310 pF1KB9 LFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVS :::::::::::::::::::::::::::::: XP_016 MSDQCPCLCIKELWVLLIHLLDHRSKWFVS 10 20 30 320 330 340 350 360 370 pF1KB9 ESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEM 40 50 60 70 80 90 380 390 pF1KB9 RKVESNWNFVEELLKKSISVQ--------------------------------------- ::::::::::::::::::::: XP_016 RKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKN 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB9 -NSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVK 160 170 180 190 200 210 460 470 480 490 500 510 pF1KB9 KAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLD 220 230 240 250 260 270 520 530 540 550 560 570 pF1KB9 LLNFLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEE :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEE 280 290 300 310 320 330 580 590 600 610 620 630 pF1KB9 MVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQ 340 350 360 370 380 390 640 650 660 670 680 690 pF1KB9 AVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQV 400 410 420 430 440 450 700 710 720 730 740 750 pF1KB9 VPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQ 460 470 480 490 500 510 760 770 780 790 800 810 pF1KB9 NSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQL 520 530 540 550 560 570 820 830 840 850 860 870 pF1KB9 VKLTRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVT :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: XP_016 VKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVT 580 590 600 610 620 630 880 890 900 910 920 930 pF1KB9 KSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCL 640 650 660 670 680 690 940 950 960 970 980 990 pF1KB9 LLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGR 700 710 720 730 740 750 1000 1010 1020 1030 1040 1050 pF1KB9 FLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASIL 760 770 780 790 800 810 1060 1070 1080 1090 1100 1110 pF1KB9 AFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPS 820 830 840 850 860 870 1120 1130 1140 1150 1160 1170 pF1KB9 SQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRN 880 890 900 910 920 930 1180 1190 1200 pF1KB9 IAQREAYSKLLSHLGQMGQDEMQRLENDNT :::::::::::::::::::::::::::::: XP_016 IAQREAYSKLLSHLGQMGQDEMQRLENDNT 940 950 960 >>XP_006715493 (OMIM: 615614) PREDICTED: protein MMS22-l (1243 aa) initn: 7917 init1: 5244 opt: 5244 Z-score: 6351.0 bits: 1187.2 E(85289): 0 Smith-Waterman score: 7788; 96.6% identity (96.7% similar) in 1235 aa overlap (9-1203:9-1243) 10 20 30 40 50 60 pF1KB9 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS 310 320 330 340 350 360 370 380 390 pF1KB9 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQ-------------------------- :::::::::::::::::::::::::::::::::: XP_006 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNI 370 380 390 400 410 420 400 410 420 430 440 pF1KB9 --------------NSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS :::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 VAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_006 VAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB9 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB9 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB9 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB9 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_006 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYG 850 860 870 880 890 900 870 880 890 900 910 920 pF1KB9 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS 910 920 930 940 950 960 930 940 950 960 970 980 pF1KB9 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KB9 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KB9 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB9 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 pF1KB9 LKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT ::::::::::::::::::::::::::::::::::::::::::: XP_006 LKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT 1210 1220 1230 1240 >>NP_940870 (OMIM: 615614) protein MMS22-like [Homo sapi (1243 aa) initn: 7917 init1: 5244 opt: 5244 Z-score: 6351.0 bits: 1187.2 E(85289): 0 Smith-Waterman score: 7788; 96.6% identity (96.7% similar) in 1235 aa overlap (9-1203:9-1243) 10 20 30 40 50 60 pF1KB9 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS 310 320 330 340 350 360 370 380 390 pF1KB9 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQ-------------------------- :::::::::::::::::::::::::::::::::: NP_940 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNI 370 380 390 400 410 420 400 410 420 430 440 pF1KB9 --------------NSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS :::::::::::::::::::::::::::::::::::::::::::::: NP_940 AIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 VAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_940 VAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB9 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB9 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB9 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB9 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_940 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYG 850 860 870 880 890 900 870 880 890 900 910 920 pF1KB9 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS 910 920 930 940 950 960 930 940 950 960 970 980 pF1KB9 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KB9 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KB9 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB9 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 pF1KB9 LKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT ::::::::::::::::::::::::::::::::::::::::::: NP_940 LKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT 1210 1220 1230 1240 >>XP_011533981 (OMIM: 615614) PREDICTED: protein MMS22-l (858 aa) initn: 5111 init1: 5080 opt: 5080 Z-score: 6154.5 bits: 1150.4 E(85289): 0 Smith-Waterman score: 5080; 99.1% identity (99.5% similar) in 789 aa overlap (395-1183:32-820) 370 380 390 400 410 420 pF1KB9 DRHGVPDEMRKVESNWNFVEELLKKSISVQNSSFSISWLPFKGLANTMKSPLSMLEMVKT :::::::::::::::::::::::::::::: XP_011 YLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKT 10 20 30 40 50 60 430 440 450 460 470 480 pF1KB9 CCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELT 70 80 90 100 110 120 490 500 510 520 530 540 pF1KB9 EVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLMYAQK ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_011 EVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQK 130 140 150 160 170 180 550 560 570 580 590 600 pF1KB9 NLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPS 190 200 210 220 230 240 610 620 630 640 650 660 pF1KB9 HEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLS 250 260 270 280 290 300 670 680 690 700 710 720 pF1KB9 AKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQ 310 320 330 340 350 360 730 740 750 760 770 780 pF1KB9 PVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQM 370 380 390 400 410 420 790 800 810 820 830 840 pF1KB9 YIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSISEDP ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_011 YIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDP 430 440 450 460 470 480 850 860 870 880 890 900 pF1KB9 KKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYG 490 500 510 520 530 540 910 920 930 940 950 960 pF1KB9 MMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQG 550 560 570 580 590 600 970 980 990 1000 1010 1020 pF1KB9 MCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISS 610 620 630 640 650 660 1030 1040 1050 1060 1070 1080 pF1KB9 LKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLV 670 680 690 700 710 720 1090 1100 1110 1120 1130 1140 pF1KB9 SEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVAT 730 740 750 760 770 780 1150 1160 1170 1180 1190 1200 pF1KB9 LDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT :::::::::::::::::::::::::::::::: . . :: XP_011 LDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQSDRFRKLYISAVLLLLKTHFSVPHWEVD 790 800 810 820 830 840 XP_011 FIALDVLFFNKIYGGKS 850 >>XP_011533980 (OMIM: 615614) PREDICTED: protein MMS22-l (967 aa) initn: 5618 init1: 5080 opt: 5080 Z-score: 6153.8 bits: 1150.4 E(85289): 0 Smith-Waterman score: 5542; 94.7% identity (95.2% similar) in 910 aa overlap (314-1183:20-929) 290 300 310 320 330 340 pF1KB9 MSDQCPCLCIKELWVLLIHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQ .::::::::::::::::::::::::::::: XP_011 MKVSKIVNYWMEEEDVVTCKSFWNWLNKLLKTLLEKSSDRRRSSMPVIQ 10 20 30 40 350 360 370 380 390 pF1KB9 SRDPLGFSWWIITHVASFYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQ--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRDPLGFSWWIITHVASFYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLR 50 60 70 80 90 100 400 410 420 pF1KB9 -------------------------------NSSFSISWLPFKGLANTMKSPLSMLEMVK ::::::::::::::::::::::::::::: XP_011 MYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVK 110 120 130 140 150 160 430 440 450 460 470 480 pF1KB9 TCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEEL 170 180 190 200 210 220 490 500 510 520 530 540 pF1KB9 TEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLMYAQ :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 TEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQ 230 240 250 260 270 280 550 560 570 580 590 600 pF1KB9 KNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYP 290 300 310 320 330 340 610 620 630 640 650 660 pF1KB9 SHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSL 350 360 370 380 390 400 670 680 690 700 710 720 pF1KB9 SAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQP 410 420 430 440 450 460 730 740 750 760 770 780 pF1KB9 QPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQ 470 480 490 500 510 520 790 800 810 820 830 840 pF1KB9 MYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSISED :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: XP_011 MYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISED 530 540 550 560 570 580 850 860 870 880 890 900 pF1KB9 PKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTY 590 600 610 620 630 640 910 920 930 940 950 960 pF1KB9 GMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQ 650 660 670 680 690 700 970 980 990 1000 1010 1020 pF1KB9 GMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPIS 710 720 730 740 750 760 1030 1040 1050 1060 1070 1080 pF1KB9 SLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVL 770 780 790 800 810 820 1090 1100 1110 1120 1130 1140 pF1KB9 VSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVA 830 840 850 860 870 880 1150 1160 1170 1180 1190 1200 pF1KB9 TLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT ::::::::::::::::::::::::::::::::: . . :: XP_011 TLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQSDRFRKLYISAVLLLLKTHFSVPHWEV 890 900 910 920 930 940 XP_011 DFIALDVLFFNKIYGGKS 950 960 >>XP_011533979 (OMIM: 615614) PREDICTED: protein MMS22-l (978 aa) initn: 5850 init1: 5080 opt: 5080 Z-score: 6153.7 bits: 1150.4 E(85289): 0 Smith-Waterman score: 5774; 95.0% identity (95.3% similar) in 940 aa overlap (284-1183:1-940) 260 270 280 290 300 310 pF1KB9 LFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVS :::::::::::::::::::::::::::::: XP_011 MSDQCPCLCIKELWVLLIHLLDHRSKWFVS 10 20 30 320 330 340 350 360 370 pF1KB9 ESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEM 40 50 60 70 80 90 380 390 pF1KB9 RKVESNWNFVEELLKKSISVQ--------------------------------------- ::::::::::::::::::::: XP_011 RKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKN 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB9 -NSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVK 160 170 180 190 200 210 460 470 480 490 500 510 pF1KB9 KAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLD 220 230 240 250 260 270 520 530 540 550 560 570 pF1KB9 LLNFLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEE :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEE 280 290 300 310 320 330 580 590 600 610 620 630 pF1KB9 MVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQ 340 350 360 370 380 390 640 650 660 670 680 690 pF1KB9 AVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQV 400 410 420 430 440 450 700 710 720 730 740 750 pF1KB9 VPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQ 460 470 480 490 500 510 760 770 780 790 800 810 pF1KB9 NSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQL 520 530 540 550 560 570 820 830 840 850 860 870 pF1KB9 VKLTRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVT :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: XP_011 VKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVT 580 590 600 610 620 630 880 890 900 910 920 930 pF1KB9 KSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCL 640 650 660 670 680 690 940 950 960 970 980 990 pF1KB9 LLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGR 700 710 720 730 740 750 1000 1010 1020 1030 1040 1050 pF1KB9 FLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASIL 760 770 780 790 800 810 1060 1070 1080 1090 1100 1110 pF1KB9 AFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPS 820 830 840 850 860 870 1120 1130 1140 1150 1160 1170 pF1KB9 SQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRN 880 890 900 910 920 930 1180 1190 1200 pF1KB9 IAQREAYSKLLSHLGQMGQDEMQRLENDNT ::: . . :: XP_011 IAQSDRFRKLYISAVLLLLKTHFSVPHWEVDFIALDVLFFNKIYGGKS 940 950 960 970 >>XP_011533978 (OMIM: 615614) PREDICTED: protein MMS22-l (1035 aa) initn: 6216 init1: 5080 opt: 5080 Z-score: 6153.3 bits: 1150.4 E(85289): 0 Smith-Waterman score: 6140; 95.3% identity (95.6% similar) in 997 aa overlap (227-1183:1-997) 200 210 220 230 240 250 pF1KB9 NQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFE :::::::::::::::::::::::::::::: XP_011 MLGEKLKQVVYGHQFMNLASDNLTNISLFE 10 20 30 260 270 280 290 300 310 pF1KB9 EHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESF 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB9 WNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKV 100 110 120 130 140 150 380 390 pF1KB9 ESNWNFVEELLKKSISVQ----------------------------------------NS :::::::::::::::::: :: XP_011 ESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNS 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB9 SFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAM 220 230 240 250 260 270 460 470 480 490 500 510 pF1KB9 KSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLN 280 290 300 310 320 330 520 530 540 550 560 570 pF1KB9 FLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQ ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQ 340 350 360 370 380 390 580 590 600 610 620 630 pF1KB9 RQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVL 400 410 420 430 440 450 640 650 660 670 680 690 pF1KB9 ARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPF 460 470 480 490 500 510 700 710 720 730 740 750 pF1KB9 SQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNST 520 530 540 550 560 570 760 770 780 790 800 810 pF1KB9 LCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKL 580 590 600 610 620 630 820 830 840 850 860 870 pF1KB9 TRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSL 640 650 660 670 680 690 880 890 900 910 920 930 pF1KB9 EYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLP 700 710 720 730 740 750 940 950 960 970 980 990 pF1KB9 HAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLP 760 770 780 790 800 810 1000 1010 1020 1030 1040 1050 pF1KB9 ASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFI 820 830 840 850 860 870 1060 1070 1080 1090 1100 1110 pF1KB9 LQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQL 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 pF1KB9 TSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQ 940 950 960 970 980 990 1180 1190 1200 pF1KB9 REAYSKLLSHLGQMGQDEMQRLENDNT . . :: XP_011 SDRFRKLYISAVLLLLKTHFSVPHWEVDFIALDVLFFNKIYGGKS 1000 1010 1020 1030 >>XP_016866145 (OMIM: 615614) PREDICTED: protein MMS22-l (1035 aa) initn: 6216 init1: 5080 opt: 5080 Z-score: 6153.3 bits: 1150.4 E(85289): 0 Smith-Waterman score: 6140; 95.3% identity (95.6% similar) in 997 aa overlap (227-1183:1-997) 200 210 220 230 240 250 pF1KB9 NQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFE :::::::::::::::::::::::::::::: XP_016 MLGEKLKQVVYGHQFMNLASDNLTNISLFE 10 20 30 260 270 280 290 300 310 pF1KB9 EHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESF 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB9 WNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKV 100 110 120 130 140 150 380 390 pF1KB9 ESNWNFVEELLKKSISVQ----------------------------------------NS :::::::::::::::::: :: XP_016 ESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNS 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB9 SFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAM 220 230 240 250 260 270 460 470 480 490 500 510 pF1KB9 KSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLN 280 290 300 310 320 330 520 530 540 550 560 570 pF1KB9 FLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQ ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQ 340 350 360 370 380 390 580 590 600 610 620 630 pF1KB9 RQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVL 400 410 420 430 440 450 640 650 660 670 680 690 pF1KB9 ARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPF 460 470 480 490 500 510 700 710 720 730 740 750 pF1KB9 SQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNST 520 530 540 550 560 570 760 770 780 790 800 810 pF1KB9 LCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKL 580 590 600 610 620 630 820 830 840 850 860 870 pF1KB9 TRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 TRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSL 640 650 660 670 680 690 880 890 900 910 920 930 pF1KB9 EYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLP 700 710 720 730 740 750 940 950 960 970 980 990 pF1KB9 HAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLP 760 770 780 790 800 810 1000 1010 1020 1030 1040 1050 pF1KB9 ASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFI 820 830 840 850 860 870 1060 1070 1080 1090 1100 1110 pF1KB9 LQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQL 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 pF1KB9 TSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQ 940 950 960 970 980 990 1180 1190 1200 pF1KB9 REAYSKLLSHLGQMGQDEMQRLENDNT . . :: XP_016 SDRFRKLYISAVLLLLKTHFSVPHWEVDFIALDVLFFNKIYGGKS 1000 1010 1020 1030 >>XP_011533972 (OMIM: 615614) PREDICTED: protein MMS22-l (1261 aa) initn: 7753 init1: 5080 opt: 5080 Z-score: 6152.0 bits: 1150.4 E(85289): 0 Smith-Waterman score: 7624; 96.1% identity (96.4% similar) in 1215 aa overlap (9-1183:9-1223) 10 20 30 40 50 60 pF1KB9 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVAS 310 320 330 340 350 360 370 380 390 pF1KB9 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQ-------------------------- :::::::::::::::::::::::::::::::::: XP_011 FYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNI 370 380 390 400 410 420 400 410 420 430 440 pF1KB9 --------------NSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS :::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAA 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 VAEVEDVASHVLDLLNFLKPAFVMSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_011 VAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFR 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRAC 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB9 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRH 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB9 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIIC 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB9 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKN 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB9 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQAEYLSISEDPKKALVRFFEAVGVTYG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_011 LEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYG 850 860 870 880 890 900 870 880 890 900 910 920 pF1KB9 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATS 910 920 930 940 950 960 930 940 950 960 970 980 pF1KB9 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLN 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KB9 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEY 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KB9 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYM 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB9 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 pF1KB9 LKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT :::::::::::::::: . . :: XP_011 LKDSEQKWGLGRNIAQSDRFRKLYISAVLLLLKTHFSVPHWEVDFIALDVLFFNKIYGGK 1210 1220 1230 1240 1250 1260 1203 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:56:05 2016 done: Thu Nov 3 23:56:07 2016 Total Scan time: 12.900 Total Display time: 0.460 Function used was FASTA [36.3.4 Apr, 2011]