FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9494, 840 aa
1>>>pF1KB9494 840 - 840 aa - 840 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9543+/-0.000356; mu= 17.6004+/- 0.022
mean_var=105.3666+/-23.568, 0's: 0 Z-trim(115.8): 232 B-trim: 146 in 1/49
Lambda= 0.124946
statistics sampled from 26192 (26477) to 26192 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.31), width: 16
Scan time: 13.420
The best scores are: opt bits E(85289)
NP_006758 (OMIM: 600574,615670,616564) leucine-zip ( 840) 5733 1045.0 0
NP_476502 (OMIM: 611248) kelch domain-containing p ( 382) 280 61.7 7.2e-09
NP_061867 (OMIM: 609109) F-box only protein 42 [Ho ( 717) 258 58.0 1.8e-07
XP_006710761 (OMIM: 609109) PREDICTED: F-box only ( 717) 258 58.0 1.8e-07
XP_016869669 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 245 55.3 4.3e-07
XP_016869671 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 245 55.3 4.3e-07
XP_016869670 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 245 55.3 4.3e-07
XP_005251701 (OMIM: 605962) PREDICTED: rab9 effect ( 275) 245 55.3 4.4e-07
XP_016869667 (OMIM: 605962) PREDICTED: rab9 effect ( 318) 240 54.5 9.2e-07
XP_005251699 (OMIM: 605962) PREDICTED: rab9 effect ( 326) 240 54.5 9.4e-07
NP_001007229 (OMIM: 602650) speckle-type POZ prote ( 374) 239 54.3 1.2e-06
NP_001007228 (OMIM: 602650) speckle-type POZ prote ( 374) 239 54.3 1.2e-06
NP_001007230 (OMIM: 602650) speckle-type POZ prote ( 374) 239 54.3 1.2e-06
NP_001007231 (OMIM: 602650) speckle-type POZ prote ( 374) 239 54.3 1.2e-06
NP_001007227 (OMIM: 602650) speckle-type POZ prote ( 374) 239 54.3 1.2e-06
NP_003554 (OMIM: 602650) speckle-type POZ protein ( 374) 239 54.3 1.2e-06
XP_016880693 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 239 54.3 1.2e-06
XP_005257780 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 239 54.3 1.2e-06
XP_005257781 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 239 54.3 1.2e-06
XP_011534912 (OMIM: 611280) PREDICTED: kelch domai ( 334) 235 53.6 1.8e-06
NP_055130 (OMIM: 611280) kelch domain-containing p ( 406) 235 53.6 2.1e-06
XP_006720157 (OMIM: 611280) PREDICTED: kelch domai ( 368) 228 52.3 4.6e-06
XP_005247610 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
NP_060114 (OMIM: 611295) kelch-like protein 24 [Ho ( 600) 221 51.3 1.6e-05
XP_005247609 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_005247611 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_005247613 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_011511240 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_016862149 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_005247612 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_016862148 (OMIM: 611295) PREDICTED: kelch-like ( 600) 221 51.3 1.6e-05
XP_016862147 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862140 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862139 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862143 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862145 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862141 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862142 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862146 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_016862144 (OMIM: 611295) PREDICTED: kelch-like ( 625) 221 51.3 1.6e-05
XP_005250290 (OMIM: 615152) PREDICTED: kelch domai ( 413) 204 48.1 0.0001
NP_055812 (OMIM: 615152) kelch domain-containing p ( 442) 204 48.1 0.00011
XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 202 47.7 0.00012
XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 202 47.7 0.00012
XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 391) 202 47.7 0.00012
XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 401) 202 47.7 0.00013
NP_001401 (OMIM: 604267,614976) multiple epidermal (2778) 213 50.4 0.00014
NP_001258867 (OMIM: 604267,614976) multiple epider (2845) 213 50.4 0.00014
XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 612) 202 47.8 0.00017
NP_443125 (OMIM: 611237) BTB/POZ domain-containing ( 612) 202 47.8 0.00017
>>NP_006758 (OMIM: 600574,615670,616564) leucine-zipper- (840 aa)
initn: 5733 init1: 5733 opt: 5733 Z-score: 5588.0 bits: 1045.0 E(85289): 0
Smith-Waterman score: 5733; 100.0% identity (100.0% similar) in 840 aa overlap (1-840:1-840)
10 20 30 40 50 60
pF1KB9 MAGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 SRDVFGLDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SRDVFGLDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LAQKLEQEAAPVPREAPGVAAGGARPPLLHVAIREAEARPFEVLMQFLYTDKIKYPRKGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LAQKLEQEAAPVPREAPGVAAGGARPPLLHVAIREAEARPFEVLMQFLYTDKIKYPRKGH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 VEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLSQLKEHCLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLSQLKEHCLN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 FVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPLDQPVDIGTSLIQDMKAYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPLDQPVDIGTSLIQDMKAYLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 GAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 ESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 DKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI
790 800 810 820 830 840
>>NP_476502 (OMIM: 611248) kelch domain-containing prote (382 aa)
initn: 246 init1: 128 opt: 280 Z-score: 280.3 bits: 61.7 E(85289): 7.2e-09
Smith-Waterman score: 301; 29.5% identity (55.6% similar) in 241 aa overlap (52-278:113-336)
30 40 50 60 70 80
pF1KB9 SKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIY
:.: : . : . :. :.. . .:
NP_476 VLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFT-PRVSGTVPGARDGHSACVLGKIMY
90 100 110 120 130 140
90 100 110 120 130
pF1KB9 VFGG--DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYT--
.::: ... . ::. ..:.. .: : :.: : :::.. :: :.:::: .
NP_476 IFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADR
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB9 -GDIYSNSNLK-NKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDG
: ..::... :. .:. . : : . :: .: .:.: :. .:.::.::
NP_476 FGPFHSNNEIYCNRIRVFDTR--TEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGY--
210 220 230 240 250
200 210 220 230 240
pF1KB9 NARLN----DMWTIGLQDRELTCWEEVAQSGEIP-P---SCCNFPVAVCRDKMFVFSGQS
::::: :.: .. .: :... .:. : : .:: . ::. .:.: :
NP_476 NARLNRHFHDLWK--FNPVSFT-WKKIEPKGKGPCPRRRQCC----CIVGDKIVLFGGTS
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB9 GAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTL
. . .:.. :.. :.: ::
NP_476 PSPEEGLGDEFDLIDHS-----DLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELN
320 330 340 350 360
310 320 330 340 350 360
pF1KB9 PNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSRDVFGL
NP_476 AMTTNSNISRPIVSSHG
370 380
>>NP_061867 (OMIM: 609109) F-box only protein 42 [Homo s (717 aa)
initn: 334 init1: 125 opt: 258 Z-score: 255.2 bits: 58.0 E(85289): 1.8e-07
Smith-Waterman score: 258; 24.8% identity (57.3% similar) in 262 aa overlap (53-294:103-356)
30 40 50 60 70
pF1KB9 KVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWR-RLPPCDEFVGARRSKHTVVAY--KDA
.:. : : ..: .:.. : ...
NP_061 LVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQS
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB9 IYVFGG---DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGY
.::::: .. .. .::: :.:... : : ...:. :.:. . ::: . . .:::.
NP_061 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB9 TGDIYSNSNLKNKNDLFE--YKFATGQ-WTEWKIEGRLPVARSAHGATVYSDKLWIFAGY
: : :.. . .:. . .. .. : . . . : ..:.. : .::. .:.:
NP_061 TRP--SPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGS
200 210 220 230 240 250
200 210 220 230 240 250
pF1KB9 DGNARL-NDMWTIGLQDRELTCWEEVAQSGEIP-PSCCNFPVAVCRDKMFVFSGQSGAKI
:. .. ::.:.. : : : . :: : : . ... .....: .:
NP_061 LGSRQMSNDVWVL---DLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGG---
260 270 280 290 300
260 270 280 290 300
pF1KB9 TNNLFQ----FEFKDKTWTRIP--TEHLLRGSPP---PPQRRYGHTMVAFDRHLYVFGGA
: ::. ..... :. : .:. .:.: : : :. .:.:..
NP_061 PNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB9 ADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSR
NP_061 SPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSR
370 380 390 400 410 420
>>XP_006710761 (OMIM: 609109) PREDICTED: F-box only prot (717 aa)
initn: 334 init1: 125 opt: 258 Z-score: 255.2 bits: 58.0 E(85289): 1.8e-07
Smith-Waterman score: 258; 24.8% identity (57.3% similar) in 262 aa overlap (53-294:103-356)
30 40 50 60 70
pF1KB9 KVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWR-RLPPCDEFVGARRSKHTVVAY--KDA
.:. : : ..: .:.. : ...
XP_006 LVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQS
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB9 IYVFGG---DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGY
.::::: .. .. .::: :.:... : : ...:. :.:. . ::: . . .:::.
XP_006 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB9 TGDIYSNSNLKNKNDLFE--YKFATGQ-WTEWKIEGRLPVARSAHGATVYSDKLWIFAGY
: : :.. . .:. . .. .. : . . . : ..:.. : .::. .:.:
XP_006 TRP--SPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGS
200 210 220 230 240 250
200 210 220 230 240 250
pF1KB9 DGNARL-NDMWTIGLQDRELTCWEEVAQSGEIP-PSCCNFPVAVCRDKMFVFSGQSGAKI
:. .. ::.:.. : : : . :: : : . ... .....: .:
XP_006 LGSRQMSNDVWVL---DLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGG---
260 270 280 290 300
260 270 280 290 300
pF1KB9 TNNLFQ----FEFKDKTWTRIP--TEHLLRGSPP---PPQRRYGHTMVAFDRHLYVFGGA
: ::. ..... :. : .:. .:.: : : :. .:.:..
XP_006 PNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB9 ADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSR
XP_006 SPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSR
370 380 390 400 410 420
>>XP_016869669 (OMIM: 605962) PREDICTED: rab9 effector p (267 aa)
initn: 324 init1: 171 opt: 245 Z-score: 248.2 bits: 55.3 E(85289): 4.3e-07
Smith-Waterman score: 245; 25.7% identity (55.7% similar) in 183 aa overlap (59-236:28-202)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_016 MKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNL
: . ..:. .:. .: . : :.::.::. : :. :...:. :: .:: . .
XP_016 NPNRSFSDVHTMDLDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYD---
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 KNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIG
:: .. .: . . : :.. .::.:.... ...::.:. . :. :.
XP_016 ----DLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYH
120 130 140 150 160
210 220 230 240 250 260
pF1KB9 LQDRELTC--WEEVAQSGEIPPSCCNFPVAV-CRDKMFVFSGQSGAKITNNLFQFEFKDK
.... : .. . :.. : : .: : :
XP_016 TEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMS
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
XP_016 HSGDSHEESQTATLLCLVFGGMNTEGEIYDDCIVTVVD
230 240 250 260
>>XP_016869671 (OMIM: 605962) PREDICTED: rab9 effector p (267 aa)
initn: 324 init1: 171 opt: 245 Z-score: 248.2 bits: 55.3 E(85289): 4.3e-07
Smith-Waterman score: 245; 25.7% identity (55.7% similar) in 183 aa overlap (59-236:28-202)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_016 MKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNL
: . ..:. .:. .: . : :.::.::. : :. :...:. :: .:: . .
XP_016 NPNRSFSDVHTMDLDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYD---
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 KNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIG
:: .. .: . . : :.. .::.:.... ...::.:. . :. :.
XP_016 ----DLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYH
120 130 140 150 160
210 220 230 240 250 260
pF1KB9 LQDRELTC--WEEVAQSGEIPPSCCNFPVAV-CRDKMFVFSGQSGAKITNNLFQFEFKDK
.... : .. . :.. : : .: : :
XP_016 TEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMS
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
XP_016 HSGDSHEESQTATLLCLVFGGMNTEGEIYDDCIVTVVD
230 240 250 260
>>XP_016869670 (OMIM: 605962) PREDICTED: rab9 effector p (267 aa)
initn: 324 init1: 171 opt: 245 Z-score: 248.2 bits: 55.3 E(85289): 4.3e-07
Smith-Waterman score: 245; 25.7% identity (55.7% similar) in 183 aa overlap (59-236:28-202)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_016 MKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNL
: . ..:. .:. .: . : :.::.::. : :. :...:. :: .:: . .
XP_016 NPNRSFSDVHTMDLDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYD---
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 KNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIG
:: .. .: . . : :.. .::.:.... ...::.:. . :. :.
XP_016 ----DLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYH
120 130 140 150 160
210 220 230 240 250 260
pF1KB9 LQDRELTC--WEEVAQSGEIPPSCCNFPVAV-CRDKMFVFSGQSGAKITNNLFQFEFKDK
.... : .. . :.. : : .: : :
XP_016 TEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMS
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
XP_016 HSGDSHEESQTATLLCLVFGGMNTEGEIYDDCIVTVVD
230 240 250 260
>>XP_005251701 (OMIM: 605962) PREDICTED: rab9 effector p (275 aa)
initn: 324 init1: 171 opt: 245 Z-score: 248.1 bits: 55.3 E(85289): 4.4e-07
Smith-Waterman score: 245; 25.7% identity (55.7% similar) in 183 aa overlap (59-236:36-210)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_005 EDTMKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNL
: . ..:. .:. .: . : :.::.::. : :. :...:. :: .:: . .
XP_005 NPNRSFSDVHTMDLDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYD---
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB9 KNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIG
:: .. .: . . : :.. .::.:.... ...::.:. . :. :.
XP_005 ----DLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYH
130 140 150 160 170
210 220 230 240 250 260
pF1KB9 LQDRELTC--WEEVAQSGEIPPSCCNFPVAV-CRDKMFVFSGQSGAKITNNLFQFEFKDK
.... : .. . :.. : : .: : :
XP_005 TEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMS
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
XP_005 HSGDSHEESQTATLLCLVFGGMNTEGEIYDDCIVTVVD
240 250 260 270
>>XP_016869667 (OMIM: 605962) PREDICTED: rab9 effector p (318 aa)
initn: 318 init1: 165 opt: 240 Z-score: 242.4 bits: 54.5 E(85289): 9.2e-07
Smith-Waterman score: 248; 24.2% identity (52.5% similar) in 236 aa overlap (59-289:28-244)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_016 MKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSS---MFVFGGYTGDIYSN
: . ..:. .:. .: : :::.:.. . . . ..:::: .:
XP_016 NPNRSFSDVHTMDLGKHQWDLDTCKGL--LPRYEHASFIPSCTPDRIWVFGG------AN
60 70 80 90 100
150 160 170 180 190 200
pF1KB9 SNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMW
.. :.: : . : :.. . : : : .: .. . ::.: .: :. .:.
XP_016 QS-GNRNCLQVLNPDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLH
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB9 TIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDK
: ..: . :... .: : .: ... ....:.:.. : ....:.. ...
XP_016 CIDISDMK---WQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQ
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
:: . . :: :: : :.:
XP_016 HWTLLKFDTLL----PPG--RLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKV
230 240 250 260 270
>>XP_005251699 (OMIM: 605962) PREDICTED: rab9 effector p (326 aa)
initn: 318 init1: 165 opt: 240 Z-score: 242.2 bits: 54.5 E(85289): 9.4e-07
Smith-Waterman score: 248; 24.2% identity (52.5% similar) in 236 aa overlap (59-289:36-252)
30 40 50 60 70 80
pF1KB9 DFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVV--AYKDAIYVFGGD
:: . :: : : : . ... ::
XP_005 EDTMKQLPVLEPGDKPRKATWYTLTVPGDSPCAR-VGHSCSYLPPVGNAKRGKVFIVGGA
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB9 NGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSS---MFVFGGYTGDIYSN
: . ..:. .:. .: : :::.:.. . . . ..:::: .:
XP_005 NPNRSFSDVHTMDLGKHQWDLDTCKGL--LPRYEHASFIPSCTPDRIWVFGG------AN
70 80 90 100 110
150 160 170 180 190 200
pF1KB9 SNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMW
.. :.: : . : :.. . : : : .: .. . ::.: .: :. .:.
XP_005 QS-GNRNCLQVLNPDTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLH
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB9 TIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDK
: ..: . :... .: : .: ... ....:.:.. : ....:.. ...
XP_005 CIDISDMK---WQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQ
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB9 TWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEV
:: . . :: :: : :.:
XP_005 HWTLLKFDTLL----PPG--RLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKV
240 250 260 270 280
840 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:57:45 2016 done: Thu Nov 3 23:57:46 2016
Total Scan time: 13.420 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]