FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9497, 1175 aa 1>>>pF1KB9497 1175 - 1175 aa - 1175 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7514+/-0.000421; mu= 20.2217+/- 0.026 mean_var=87.4433+/-17.919, 0's: 0 Z-trim(113.1): 152 B-trim: 1235 in 2/51 Lambda= 0.137155 statistics sampled from 22108 (22327) to 22108 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.262), width: 16 Scan time: 16.700 The best scores are: opt bits E(85289) NP_001135445 (OMIM: 606693,610513) probable cation (1175) 7795 1553.5 0 XP_016856334 (OMIM: 606693,610513) PREDICTED: prob (1174) 7777 1550.0 0 NP_071372 (OMIM: 606693,610513) probable cation-tr (1180) 7775 1549.6 0 XP_016856333 (OMIM: 606693,610513) PREDICTED: prob (1175) 7715 1537.7 0 XP_005245868 (OMIM: 606693,610513) PREDICTED: prob (1197) 7128 1421.6 0 XP_006710575 (OMIM: 606693,610513) PREDICTED: prob (1196) 7110 1418.0 0 XP_005245867 (OMIM: 606693,610513) PREDICTED: prob (1201) 7106 1417.2 0 XP_011539430 (OMIM: 606693,610513) PREDICTED: prob (1197) 7048 1405.7 0 XP_005245869 (OMIM: 606693,610513) PREDICTED: prob (1193) 6521 1301.4 0 XP_016856335 (OMIM: 606693,610513) PREDICTED: prob (1166) 6175 1233.0 0 XP_016856336 (OMIM: 606693,610513) PREDICTED: prob (1165) 6115 1221.1 0 XP_006710576 (OMIM: 606693,610513) PREDICTED: prob (1188) 5508 1101.0 0 XP_016856338 (OMIM: 606693,610513) PREDICTED: prob (1136) 5357 1071.1 0 NP_001135446 (OMIM: 606693,610513) probable cation (1158) 5357 1071.1 0 XP_016856337 (OMIM: 606693,610513) PREDICTED: prob (1141) 5337 1067.2 0 XP_005245872 (OMIM: 606693,610513) PREDICTED: prob (1163) 5337 1067.2 0 XP_016856339 (OMIM: 606693,610513) PREDICTED: prob (1111) 3888 780.4 0 XP_011539431 (OMIM: 606693,610513) PREDICTED: prob (1133) 3221 648.5 7.1e-185 XP_016862807 (OMIM: 609556) PREDICTED: probable ca (1087) 2446 495.1 1e-138 NP_115655 (OMIM: 609556) probable cation-transport (1196) 2446 495.1 1.1e-138 XP_011511534 (OMIM: 609556) PREDICTED: probable ca ( 949) 2339 473.9 2.1e-132 XP_016862808 (OMIM: 609556) PREDICTED: probable ca ( 924) 2287 463.6 2.6e-129 XP_011511426 (OMIM: 610232) PREDICTED: probable ca (1205) 1299 268.2 2.3e-70 NP_078800 (OMIM: 610232) probable cation-transport (1226) 1299 268.2 2.3e-70 XP_011511425 (OMIM: 610232) PREDICTED: probable ca (1226) 1299 268.2 2.3e-70 XP_011511424 (OMIM: 610232) PREDICTED: probable ca (1229) 1299 268.2 2.3e-70 XP_011511422 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70 XP_011511423 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70 XP_005269414 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70 NP_001278383 (OMIM: 613082) calcium-transporting A ( 795) 224 55.3 1.8e-06 NP_055676 (OMIM: 613082) calcium-transporting ATPa ( 946) 224 55.4 2e-06 XP_016861975 (OMIM: 108733,601386) PREDICTED: plas (1199) 225 55.6 2.1e-06 XP_016861974 (OMIM: 108733,601386) PREDICTED: plas (1205) 225 55.6 2.1e-06 XP_016861971 (OMIM: 108733,601386) PREDICTED: plas (1243) 225 55.7 2.2e-06 XP_016861970 (OMIM: 108733,601386) PREDICTED: plas (1243) 225 55.7 2.2e-06 NP_001001331 (OMIM: 108733,601386) plasma membrane (1243) 225 55.7 2.2e-06 XP_011532054 (OMIM: 108733,601386) PREDICTED: plas (1243) 225 55.7 2.2e-06 XP_006713238 (OMIM: 108733,601386) PREDICTED: plas (1243) 225 55.7 2.2e-06 XP_005265236 (OMIM: 108733,601386) PREDICTED: plas (1243) 225 55.7 2.2e-06 XP_016861981 (OMIM: 108733,601386) PREDICTED: plas (1272) 225 55.7 2.2e-06 XP_016863135 (OMIM: 609542) PREDICTED: phospholipi (1007) 221 54.8 3.2e-06 XP_011510988 (OMIM: 169600,604384) PREDICTED: calc ( 671) 218 54.1 3.5e-06 XP_011511920 (OMIM: 609542) PREDICTED: phospholipi (1156) 221 54.8 3.6e-06 XP_011511917 (OMIM: 609542) PREDICTED: phospholipi (1171) 221 54.8 3.6e-06 XP_011511918 (OMIM: 609542) PREDICTED: phospholipi (1171) 221 54.8 3.6e-06 NP_001186113 (OMIM: 169600,604384) calcium-transpo ( 903) 218 54.2 4.5e-06 NP_055197 (OMIM: 169600,604384) calcium-transporti ( 919) 218 54.2 4.5e-06 NP_001186108 (OMIM: 169600,604384) calcium-transpo ( 919) 218 54.2 4.5e-06 NP_001186112 (OMIM: 169600,604384) calcium-transpo ( 923) 218 54.2 4.5e-06 XP_005247415 (OMIM: 169600,604384) PREDICTED: calc ( 933) 218 54.2 4.6e-06 >>NP_001135445 (OMIM: 606693,610513) probable cation-tra (1175 aa) initn: 7795 init1: 7795 opt: 7795 Z-score: 8331.3 bits: 1553.5 E(85289): 0 Smith-Waterman score: 7795; 100.0% identity (100.0% similar) in 1175 aa overlap (1-1175:1-1175) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR ::::::::::::::::::::::::::::::::::: NP_001 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1150 1160 1170 >>XP_016856334 (OMIM: 606693,610513) PREDICTED: probable (1174 aa) initn: 6755 init1: 6755 opt: 7777 Z-score: 8312.0 bits: 1550.0 E(85289): 0 Smith-Waterman score: 7777; 99.9% identity (99.9% similar) in 1175 aa overlap (1-1175:1-1174) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-RVLRYYLFQGQRYIWIETQQAFYQV 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1080 1090 1100 1110 1120 1130 1150 1160 1170 pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR ::::::::::::::::::::::::::::::::::: XP_016 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1140 1150 1160 1170 >>NP_071372 (OMIM: 606693,610513) probable cation-transp (1180 aa) initn: 6758 init1: 6758 opt: 7775 Z-score: 8309.8 bits: 1549.6 E(85289): 0 Smith-Waterman score: 7775; 99.6% identity (99.6% similar) in 1180 aa overlap (1-1175:1-1180) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_071 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 pF1KB9 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR :::::::::::::::::::::::::::::::::::::::: NP_071 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1150 1160 1170 1180 >>XP_016856333 (OMIM: 606693,610513) PREDICTED: probable (1175 aa) initn: 5033 init1: 5033 opt: 7715 Z-score: 8245.7 bits: 1537.7 E(85289): 0 Smith-Waterman score: 7715; 99.2% identity (99.2% similar) in 1180 aa overlap (1-1175:1-1175) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV ::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_016 TLYAQSRLRRQGIFCIHPLRINLGGKLQL-----TGTLTEDGLDVMGVVPLKGQAFLPLV 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR :::::::::::::::::::::::::::::::::::::::: XP_016 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1140 1150 1160 1170 >>XP_005245868 (OMIM: 606693,610513) PREDICTED: probable (1197 aa) initn: 7128 init1: 7128 opt: 7128 Z-score: 7617.9 bits: 1421.6 E(85289): 0 Smith-Waterman score: 7128; 100.0% identity (100.0% similar) in 1073 aa overlap (1-1073:1-1073) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERARPVP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC XP_005 PRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSHQLDP 1090 1100 1110 1120 1130 1140 >>XP_006710575 (OMIM: 606693,610513) PREDICTED: probable (1196 aa) initn: 6088 init1: 6088 opt: 7110 Z-score: 7598.6 bits: 1418.0 E(85289): 0 Smith-Waterman score: 7110; 99.9% identity (99.9% similar) in 1073 aa overlap (1-1073:1-1072) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_006 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-RVLRYYLFQGQRYIWIETQQAFYQV 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERARPVP 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC XP_006 PRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSHQLDP 1080 1090 1100 1110 1120 1130 >>XP_005245867 (OMIM: 606693,610513) PREDICTED: probable (1201 aa) initn: 6086 init1: 6086 opt: 7106 Z-score: 7594.3 bits: 1417.2 E(85289): 0 Smith-Waterman score: 7106; 99.5% identity (99.6% similar) in 1077 aa overlap (1-1073:1-1077) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA----KRVLRYYLFQGQRYIWIETQQA :::::::::::::::::::::::::::::::::: .::::::::::::::::::::: XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQRVLRYYLFQGQRYIWIETQQA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 FYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 GFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 GEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 YKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCT 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 LYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB9 EPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB9 VMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB9 GLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB9 LVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB9 ERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB9 PKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEAS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB9 VVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB9 QFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYF 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 LTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERA 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB9 LVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQC XP_005 RPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSH 1090 1100 1110 1120 1130 1140 >>XP_011539430 (OMIM: 606693,610513) PREDICTED: probable (1197 aa) initn: 4366 init1: 4366 opt: 7048 Z-score: 7532.3 bits: 1405.7 E(85289): 0 Smith-Waterman score: 7048; 99.1% identity (99.1% similar) in 1078 aa overlap (1-1073:1-1073) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_011 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV ::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_011 TLYAQSRLRRQGIFCIHPLRINLGGKLQL-----TGTLTEDGLDVMGVVPLKGQAFLPLV 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNER 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ XP_011 ARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLS 1080 1090 1100 1110 1120 1130 >>XP_005245869 (OMIM: 606693,610513) PREDICTED: probable (1193 aa) initn: 6533 init1: 5508 opt: 6521 Z-score: 6968.8 bits: 1301.4 E(85289): 0 Smith-Waterman score: 7014; 98.7% identity (98.7% similar) in 1078 aa overlap (1-1073:1-1069) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA---- 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -----FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNER 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ XP_005 ARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLS 1080 1090 1100 1110 1120 1130 >>XP_016856335 (OMIM: 606693,610513) PREDICTED: probable (1166 aa) initn: 6175 init1: 6175 opt: 6175 Z-score: 6598.9 bits: 1233.0 E(85289): 0 Smith-Waterman score: 7701; 99.2% identity (99.2% similar) in 1175 aa overlap (1-1175:1-1166) 10 20 30 40 50 60 pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA--------- 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC 1080 1090 1100 1110 1120 1130 1150 1160 1170 pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR ::::::::::::::::::::::::::::::::::: XP_016 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR 1140 1150 1160 1175 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:59:09 2016 done: Thu Nov 3 23:59:11 2016 Total Scan time: 16.700 Total Display time: 0.490 Function used was FASTA [36.3.4 Apr, 2011]