Result of FASTA (omim) for pF1KB9497
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9497, 1175 aa
  1>>>pF1KB9497 1175 - 1175 aa - 1175 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7514+/-0.000421; mu= 20.2217+/- 0.026
 mean_var=87.4433+/-17.919, 0's: 0 Z-trim(113.1): 152  B-trim: 1235 in 2/51
 Lambda= 0.137155
 statistics sampled from 22108 (22327) to 22108 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.262), width:  16
 Scan time: 16.700

The best scores are:                                      opt bits E(85289)
NP_001135445 (OMIM: 606693,610513) probable cation (1175) 7795 1553.5       0
XP_016856334 (OMIM: 606693,610513) PREDICTED: prob (1174) 7777 1550.0       0
NP_071372 (OMIM: 606693,610513) probable cation-tr (1180) 7775 1549.6       0
XP_016856333 (OMIM: 606693,610513) PREDICTED: prob (1175) 7715 1537.7       0
XP_005245868 (OMIM: 606693,610513) PREDICTED: prob (1197) 7128 1421.6       0
XP_006710575 (OMIM: 606693,610513) PREDICTED: prob (1196) 7110 1418.0       0
XP_005245867 (OMIM: 606693,610513) PREDICTED: prob (1201) 7106 1417.2       0
XP_011539430 (OMIM: 606693,610513) PREDICTED: prob (1197) 7048 1405.7       0
XP_005245869 (OMIM: 606693,610513) PREDICTED: prob (1193) 6521 1301.4       0
XP_016856335 (OMIM: 606693,610513) PREDICTED: prob (1166) 6175 1233.0       0
XP_016856336 (OMIM: 606693,610513) PREDICTED: prob (1165) 6115 1221.1       0
XP_006710576 (OMIM: 606693,610513) PREDICTED: prob (1188) 5508 1101.0       0
XP_016856338 (OMIM: 606693,610513) PREDICTED: prob (1136) 5357 1071.1       0
NP_001135446 (OMIM: 606693,610513) probable cation (1158) 5357 1071.1       0
XP_016856337 (OMIM: 606693,610513) PREDICTED: prob (1141) 5337 1067.2       0
XP_005245872 (OMIM: 606693,610513) PREDICTED: prob (1163) 5337 1067.2       0
XP_016856339 (OMIM: 606693,610513) PREDICTED: prob (1111) 3888 780.4       0
XP_011539431 (OMIM: 606693,610513) PREDICTED: prob (1133) 3221 648.5 7.1e-185
XP_016862807 (OMIM: 609556) PREDICTED: probable ca (1087) 2446 495.1  1e-138
NP_115655 (OMIM: 609556) probable cation-transport (1196) 2446 495.1 1.1e-138
XP_011511534 (OMIM: 609556) PREDICTED: probable ca ( 949) 2339 473.9 2.1e-132
XP_016862808 (OMIM: 609556) PREDICTED: probable ca ( 924) 2287 463.6 2.6e-129
XP_011511426 (OMIM: 610232) PREDICTED: probable ca (1205) 1299 268.2 2.3e-70
NP_078800 (OMIM: 610232) probable cation-transport (1226) 1299 268.2 2.3e-70
XP_011511425 (OMIM: 610232) PREDICTED: probable ca (1226) 1299 268.2 2.3e-70
XP_011511424 (OMIM: 610232) PREDICTED: probable ca (1229) 1299 268.2 2.3e-70
XP_011511422 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70
XP_011511423 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70
XP_005269414 (OMIM: 610232) PREDICTED: probable ca (1256) 1299 268.2 2.4e-70
NP_001278383 (OMIM: 613082) calcium-transporting A ( 795)  224 55.3 1.8e-06
NP_055676 (OMIM: 613082) calcium-transporting ATPa ( 946)  224 55.4   2e-06
XP_016861975 (OMIM: 108733,601386) PREDICTED: plas (1199)  225 55.6 2.1e-06
XP_016861974 (OMIM: 108733,601386) PREDICTED: plas (1205)  225 55.6 2.1e-06
XP_016861971 (OMIM: 108733,601386) PREDICTED: plas (1243)  225 55.7 2.2e-06
XP_016861970 (OMIM: 108733,601386) PREDICTED: plas (1243)  225 55.7 2.2e-06
NP_001001331 (OMIM: 108733,601386) plasma membrane (1243)  225 55.7 2.2e-06
XP_011532054 (OMIM: 108733,601386) PREDICTED: plas (1243)  225 55.7 2.2e-06
XP_006713238 (OMIM: 108733,601386) PREDICTED: plas (1243)  225 55.7 2.2e-06
XP_005265236 (OMIM: 108733,601386) PREDICTED: plas (1243)  225 55.7 2.2e-06
XP_016861981 (OMIM: 108733,601386) PREDICTED: plas (1272)  225 55.7 2.2e-06
XP_016863135 (OMIM: 609542) PREDICTED: phospholipi (1007)  221 54.8 3.2e-06
XP_011510988 (OMIM: 169600,604384) PREDICTED: calc ( 671)  218 54.1 3.5e-06
XP_011511920 (OMIM: 609542) PREDICTED: phospholipi (1156)  221 54.8 3.6e-06
XP_011511917 (OMIM: 609542) PREDICTED: phospholipi (1171)  221 54.8 3.6e-06
XP_011511918 (OMIM: 609542) PREDICTED: phospholipi (1171)  221 54.8 3.6e-06
NP_001186113 (OMIM: 169600,604384) calcium-transpo ( 903)  218 54.2 4.5e-06
NP_055197 (OMIM: 169600,604384) calcium-transporti ( 919)  218 54.2 4.5e-06
NP_001186108 (OMIM: 169600,604384) calcium-transpo ( 919)  218 54.2 4.5e-06
NP_001186112 (OMIM: 169600,604384) calcium-transpo ( 923)  218 54.2 4.5e-06
XP_005247415 (OMIM: 169600,604384) PREDICTED: calc ( 933)  218 54.2 4.6e-06


>>NP_001135445 (OMIM: 606693,610513) probable cation-tra  (1175 aa)
 initn: 7795 init1: 7795 opt: 7795  Z-score: 8331.3  bits: 1553.5 E(85289):    0
Smith-Waterman score: 7795; 100.0% identity (100.0% similar) in 1175 aa overlap (1-1175:1-1175)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170     
pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
       :::::::::::::::::::::::::::::::::::
NP_001 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
             1150      1160      1170     

>>XP_016856334 (OMIM: 606693,610513) PREDICTED: probable  (1174 aa)
 initn: 6755 init1: 6755 opt: 7777  Z-score: 8312.0  bits: 1550.0 E(85289):    0
Smith-Waterman score: 7777; 99.9% identity (99.9% similar) in 1175 aa overlap (1-1175:1-1174)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-RVLRYYLFQGQRYIWIETQQAFYQV
              130       140       150        160       170         

              190       200       210       220       230       240
pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
    1080      1090      1100      1110      1120      1130         

             1150      1160      1170     
pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
       :::::::::::::::::::::::::::::::::::
XP_016 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
    1140      1150      1160      1170    

>>NP_071372 (OMIM: 606693,610513) probable cation-transp  (1180 aa)
 initn: 6758 init1: 6758 opt: 7775  Z-score: 8309.8  bits: 1549.6 E(85289):    0
Smith-Waterman score: 7775; 99.6% identity (99.6% similar) in 1180 aa overlap (1-1175:1-1180)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150            160       170     
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ
       ::::::::::::::::::::::::::::::::::     :::::::::::::::::::::
NP_071 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
             1030      1040      1050      1060      1070      1080

        1080      1090      1100      1110      1120      1130     
pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
             1090      1100      1110      1120      1130      1140

        1140      1150      1160      1170     
pF1KB9 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
       ::::::::::::::::::::::::::::::::::::::::
NP_071 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
             1150      1160      1170      1180

>>XP_016856333 (OMIM: 606693,610513) PREDICTED: probable  (1175 aa)
 initn: 5033 init1: 5033 opt: 7715  Z-score: 8245.7  bits: 1537.7 E(85289):    0
Smith-Waterman score: 7715; 99.2% identity (99.2% similar) in 1180 aa overlap (1-1175:1-1175)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150            160       170     
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ
       ::::::::::::::::::::::::::::::::::     :::::::::::::::::::::
XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
       :::::::::::::::::::::::::::::     ::::::::::::::::::::::::::
XP_016 TLYAQSRLRRQGIFCIHPLRINLGGKLQL-----TGTLTEDGLDVMGVVPLKGQAFLPLV
              490       500            510       520       530     

         540       550       560       570       580       590     
pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
         540       550       560       570       580       590     

         600       610       620       630       640       650     
pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
         600       610       620       630       640       650     

         660       670       680       690       700       710     
pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
         660       670       680       690       700       710     

         720       730       740       750       760       770     
pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
         720       730       740       750       760       770     

         780       790       800       810       820       830     
pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
         780       790       800       810       820       830     

         840       850       860       870       880       890     
pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
         840       850       860       870       880       890     

         900       910       920       930       940       950     
pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
         900       910       920       930       940       950     

         960       970       980       990      1000      1010     
pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
         960       970       980       990      1000      1010     

        1020      1030      1040      1050      1060      1070     
pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
        1020      1030      1040      1050      1060      1070     

        1080      1090      1100      1110      1120      1130     
pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
        1080      1090      1100      1110      1120      1130     

        1140      1150      1160      1170     
pF1KB9 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
       ::::::::::::::::::::::::::::::::::::::::
XP_016 CLPACLRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
        1140      1150      1160      1170     

>>XP_005245868 (OMIM: 606693,610513) PREDICTED: probable  (1197 aa)
 initn: 7128 init1: 7128 opt: 7128  Z-score: 7617.9  bits: 1421.6 E(85289):    0
Smith-Waterman score: 7128; 100.0% identity (100.0% similar) in 1073 aa overlap (1-1073:1-1073)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_005 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERARPVP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
                                                                   
XP_005 PRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSHQLDP
             1090      1100      1110      1120      1130      1140

>>XP_006710575 (OMIM: 606693,610513) PREDICTED: probable  (1196 aa)
 initn: 6088 init1: 6088 opt: 7110  Z-score: 7598.6  bits: 1418.0 E(85289):    0
Smith-Waterman score: 7110; 99.9% identity (99.9% similar) in 1073 aa overlap (1-1073:1-1072)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_006 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-RVLRYYLFQGQRYIWIETQQAFYQV
              130       140       150        160       170         

              190       200       210       220       230       240
pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_006 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERARPVP
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
                                                                   
XP_006 PRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSHQLDP
    1080      1090      1100      1110      1120      1130         

>>XP_005245867 (OMIM: 606693,610513) PREDICTED: probable  (1201 aa)
 initn: 6086 init1: 6086 opt: 7106  Z-score: 7594.3  bits: 1417.2 E(85289):    0
Smith-Waterman score: 7106; 99.5% identity (99.6% similar) in 1077 aa overlap (1-1073:1-1077)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150           160       170      
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA----KRVLRYYLFQGQRYIWIETQQA
       ::::::::::::::::::::::::::::::::::    .:::::::::::::::::::::
XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQRVLRYYLFQGQRYIWIETQQA
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 FYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYY
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 GFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPG
              250       260       270       280       290       300

        300       310       320       330       340       350      
pF1KB9 GEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGL
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB9 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKF
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KB9 YKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCT
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KB9 LYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVP
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KB9 EPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLA
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KB9 VMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVA
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KB9 GLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGL
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KB9 LVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHP
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KB9 ERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLL
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KB9 PKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEAS
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KB9 VVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KB9 QFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYF
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KB9 LTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_005 LTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNERA
             1030      1040      1050      1060      1070      1080

       1080      1090      1100      1110      1120      1130      
pF1KB9 LVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQC
                                                                   
XP_005 RPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLSH
             1090      1100      1110      1120      1130      1140

>>XP_011539430 (OMIM: 606693,610513) PREDICTED: probable  (1197 aa)
 initn: 4366 init1: 4366 opt: 7048  Z-score: 7532.3  bits: 1405.7 E(85289):    0
Smith-Waterman score: 7048; 99.1% identity (99.1% similar) in 1078 aa overlap (1-1073:1-1073)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150            160       170     
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ
       ::::::::::::::::::::::::::::::::::     :::::::::::::::::::::
XP_011 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
       :::::::::::::::::::::::::::::     ::::::::::::::::::::::::::
XP_011 TLYAQSRLRRQGIFCIHPLRINLGGKLQL-----TGTLTEDGLDVMGVVPLKGQAFLPLV
              490       500            510       520       530     

         540       550       560       570       580       590     
pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
         540       550       560       570       580       590     

         600       610       620       630       640       650     
pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
         600       610       620       630       640       650     

         660       670       680       690       700       710     
pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
         660       670       680       690       700       710     

         720       730       740       750       760       770     
pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
         720       730       740       750       760       770     

         780       790       800       810       820       830     
pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
         780       790       800       810       820       830     

         840       850       860       870       880       890     
pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
         840       850       860       870       880       890     

         900       910       920       930       940       950     
pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
         900       910       920       930       940       950     

         960       970       980       990      1000      1010     
pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
         960       970       980       990      1000      1010     

        1020      1030      1040      1050      1060      1070     
pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNER
        1020      1030      1040      1050      1060      1070     

        1080      1090      1100      1110      1120      1130     
pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
                                                                   
XP_011 ARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLS
        1080      1090      1100      1110      1120      1130     

>>XP_005245869 (OMIM: 606693,610513) PREDICTED: probable  (1193 aa)
 initn: 6533 init1: 5508 opt: 6521  Z-score: 6968.8  bits: 1301.4 E(85289):    0
Smith-Waterman score: 7014; 98.7% identity (98.7% similar) in 1078 aa overlap (1-1073:1-1069)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150            160       170     
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ
       ::::::::::::::::::::::::::::::::::     :::::::::::::::::::::
XP_005 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KB9 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_005 AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA----
              190       200       210       220       230          

         240       250       260       270       280       290     
pF1KB9 YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -----FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
             240       250       260       270       280       290 

         300       310       320       330       340       350     
pF1KB9 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
             300       310       320       330       340       350 

         360       370       380       390       400       410     
pF1KB9 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
             360       370       380       390       400       410 

         420       430       440       450       460       470     
pF1KB9 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
             420       430       440       450       460       470 

         480       490       500       510       520       530     
pF1KB9 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
             480       490       500       510       520       530 

         540       550       560       570       580       590     
pF1KB9 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
             540       550       560       570       580       590 

         600       610       620       630       640       650     
pF1KB9 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
             600       610       620       630       640       650 

         660       670       680       690       700       710     
pF1KB9 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
             660       670       680       690       700       710 

         720       730       740       750       760       770     
pF1KB9 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
             720       730       740       750       760       770 

         780       790       800       810       820       830     
pF1KB9 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL
             780       790       800       810       820       830 

         840       850       860       870       880       890     
pF1KB9 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
             840       850       860       870       880       890 

         900       910       920       930       940       950     
pF1KB9 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
             900       910       920       930       940       950 

         960       970       980       990      1000      1010     
pF1KB9 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
             960       970       980       990      1000      1010 

        1020      1030      1040      1050      1060      1070     
pF1KB9 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_005 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNER
            1020      1030      1040      1050      1060      1070 

        1080      1090      1100      1110      1120      1130     
pF1KB9 FLVALALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQ
                                                                   
XP_005 ARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEVVQAHGHPRHWNSLPLS
            1080      1090      1100      1110      1120      1130 

>>XP_016856335 (OMIM: 606693,610513) PREDICTED: probable  (1166 aa)
 initn: 6175 init1: 6175 opt: 6175  Z-score: 6598.9  bits: 1233.0 E(85289):    0
Smith-Waterman score: 7701; 99.2% identity (99.2% similar) in 1175 aa overlap (1-1175:1-1166)

               10        20        30        40        50        60
pF1KB9 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA---------
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KB9 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KB9 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KB9 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KB9 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
             420       430       440       450       460       470 

              490       500       510       520       530       540
pF1KB9 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
             480       490       500       510       520       530 

              550       560       570       580       590       600
pF1KB9 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
             540       550       560       570       580       590 

              610       620       630       640       650       660
pF1KB9 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
             600       610       620       630       640       650 

              670       680       690       700       710       720
pF1KB9 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
             660       670       680       690       700       710 

              730       740       750       760       770       780
pF1KB9 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
             720       730       740       750       760       770 

              790       800       810       820       830       840
pF1KB9 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL
             780       790       800       810       820       830 

              850       860       870       880       890       900
pF1KB9 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
             840       850       860       870       880       890 

              910       920       930       940       950       960
pF1KB9 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
             900       910       920       930       940       950 

              970       980       990      1000      1010      1020
pF1KB9 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
             960       970       980       990      1000      1010 

             1030      1040      1050      1060      1070      1080
pF1KB9 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVAL
            1020      1030      1040      1050      1060      1070 

             1090      1100      1110      1120      1130      1140
pF1KB9 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLSSVLVGLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVLDQCLPAC
            1080      1090      1100      1110      1120      1130 

             1150      1160      1170     
pF1KB9 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
       :::::::::::::::::::::::::::::::::::
XP_016 LRRLRPKRASKKRFKQLERELAEQPWPPLPAGPLR
            1140      1150      1160      




1175 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:59:09 2016 done: Thu Nov  3 23:59:11 2016
 Total Scan time: 16.700 Total Display time:  0.490

Function used was FASTA [36.3.4 Apr, 2011]
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