FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9500, 675 aa 1>>>pF1KB9500 675 - 675 aa - 675 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3701+/-0.000493; mu= 5.1081+/- 0.030 mean_var=215.0289+/-45.013, 0's: 0 Z-trim(116.0): 220 B-trim: 1449 in 2/52 Lambda= 0.087463 statistics sampled from 26535 (26762) to 26535 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.314), width: 16 Scan time: 11.690 The best scores are: opt bits E(85289) NP_071919 (OMIM: 606958) MAGUK p55 subfamily membe ( 675) 4463 576.9 8.2e-164 XP_011535389 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 675) 4463 576.9 8.2e-164 XP_011535388 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 675) 4463 576.9 8.2e-164 XP_005268060 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 641) 4239 548.6 2.6e-155 NP_001243479 (OMIM: 606958) MAGUK p55 subfamily me ( 641) 4239 548.6 2.6e-155 NP_775767 (OMIM: 610973) MAGUK p55 subfamily membe ( 576) 1230 168.9 4.7e-41 NP_001305099 (OMIM: 610973) MAGUK p55 subfamily me ( 576) 1230 168.9 4.7e-41 XP_011517639 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 576) 1230 168.9 4.7e-41 XP_016871231 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 574) 1211 166.5 2.5e-40 XP_016871230 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 657) 1185 163.3 2.6e-39 XP_011517640 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 451) 1077 149.5 2.5e-35 NP_001119527 (OMIM: 300172,300422,300749) peripher ( 897) 891 126.3 4.9e-28 XP_011542297 (OMIM: 300172,300422,300749) PREDICTE ( 903) 891 126.3 4.9e-28 NP_001265303 (OMIM: 600723) MAGUK p55 subfamily me ( 413) 741 107.1 1.4e-22 NP_001265304 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 741 107.2 1.7e-22 NP_001265300 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 741 107.2 1.7e-22 NP_001265302 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 741 107.2 1.7e-22 NP_005365 (OMIM: 600723) MAGUK p55 subfamily membe ( 552) 741 107.2 1.7e-22 NP_001265310 (OMIM: 600723) MAGUK p55 subfamily me ( 552) 741 107.2 1.7e-22 NP_001265305 (OMIM: 600723) MAGUK p55 subfamily me ( 569) 741 107.2 1.7e-22 NP_001265301 (OMIM: 600723) MAGUK p55 subfamily me ( 576) 741 107.2 1.8e-22 NP_001265299 (OMIM: 600723) MAGUK p55 subfamily me ( 597) 741 107.2 1.8e-22 XP_006724629 (OMIM: 300172,300422,300749) PREDICTE ( 885) 744 107.8 1.9e-22 XP_011542298 (OMIM: 300172,300422,300749) PREDICTE ( 891) 744 107.8 1.9e-22 XP_011523129 (OMIM: 600723) PREDICTED: MAGUK p55 s ( 630) 741 107.3 1.9e-22 XP_005252426 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 318) 713 103.5 1.3e-21 XP_005249832 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 428) 711 103.3 2e-21 XP_011513727 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 NP_057531 (OMIM: 606959) MAGUK p55 subfamily membe ( 540) 711 103.4 2.3e-21 XP_016867806 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 XP_016867804 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 NP_001289966 (OMIM: 606959) MAGUK p55 subfamily me ( 540) 711 103.4 2.3e-21 XP_006715801 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 XP_006715803 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 XP_016867805 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 XP_006715802 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 711 103.4 2.3e-21 NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 692 101.2 1.6e-20 XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 692 101.2 1.7e-20 XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 692 101.2 1.7e-20 XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 692 101.2 1.7e-20 XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 692 101.2 1.7e-20 XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 692 101.2 1.7e-20 XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 692 101.2 1.7e-20 XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 692 101.2 1.7e-20 XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 692 101.2 1.7e-20 NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 692 101.2 1.8e-20 XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 692 101.2 1.8e-20 NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 692 101.2 1.8e-20 XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 692 101.2 1.8e-20 XP_016880147 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 340) 668 97.8 7.1e-20 >>NP_071919 (OMIM: 606958) MAGUK p55 subfamily member 5 (675 aa) initn: 4463 init1: 4463 opt: 4463 Z-score: 3061.9 bits: 576.9 E(85289): 8.2e-164 Smith-Waterman score: 4463; 100.0% identity (100.0% similar) in 675 aa overlap (1-675:1-675) 10 20 30 40 50 60 pF1KB9 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 610 620 630 640 650 660 670 pF1KB9 KLDTEPQWVPSTWLR ::::::::::::::: NP_071 KLDTEPQWVPSTWLR 670 >>XP_011535389 (OMIM: 606958) PREDICTED: MAGUK p55 subfa (675 aa) initn: 4463 init1: 4463 opt: 4463 Z-score: 3061.9 bits: 576.9 E(85289): 8.2e-164 Smith-Waterman score: 4463; 100.0% identity (100.0% similar) in 675 aa overlap (1-675:1-675) 10 20 30 40 50 60 pF1KB9 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 610 620 630 640 650 660 670 pF1KB9 KLDTEPQWVPSTWLR ::::::::::::::: XP_011 KLDTEPQWVPSTWLR 670 >>XP_011535388 (OMIM: 606958) PREDICTED: MAGUK p55 subfa (675 aa) initn: 4463 init1: 4463 opt: 4463 Z-score: 3061.9 bits: 576.9 E(85289): 8.2e-164 Smith-Waterman score: 4463; 100.0% identity (100.0% similar) in 675 aa overlap (1-675:1-675) 10 20 30 40 50 60 pF1KB9 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 610 620 630 640 650 660 670 pF1KB9 KLDTEPQWVPSTWLR ::::::::::::::: XP_011 KLDTEPQWVPSTWLR 670 >>XP_005268060 (OMIM: 606958) PREDICTED: MAGUK p55 subfa (641 aa) initn: 4239 init1: 4239 opt: 4239 Z-score: 2909.4 bits: 548.6 E(85289): 2.6e-155 Smith-Waterman score: 4239; 100.0% identity (100.0% similar) in 641 aa overlap (35-675:1-641) 10 20 30 40 50 60 pF1KB9 HMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQE :::::::::::::::::::::::::::::: XP_005 MAVDCPGDLGTRMMPIRRSAQLERIRQQQE 10 20 30 70 80 90 100 110 120 pF1KB9 DMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB9 EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB9 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB9 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB9 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDT 580 590 600 610 620 630 670 pF1KB9 EPQWVPSTWLR ::::::::::: XP_005 EPQWVPSTWLR 640 >>NP_001243479 (OMIM: 606958) MAGUK p55 subfamily member (641 aa) initn: 4239 init1: 4239 opt: 4239 Z-score: 2909.4 bits: 548.6 E(85289): 2.6e-155 Smith-Waterman score: 4239; 100.0% identity (100.0% similar) in 641 aa overlap (35-675:1-641) 10 20 30 40 50 60 pF1KB9 HMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQE :::::::::::::::::::::::::::::: NP_001 MAVDCPGDLGTRMMPIRRSAQLERIRQQQE 10 20 30 70 80 90 100 110 120 pF1KB9 DMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB9 EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB9 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB9 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB9 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDT 580 590 600 610 620 630 670 pF1KB9 EPQWVPSTWLR ::::::::::: NP_001 EPQWVPSTWLR 640 >>NP_775767 (OMIM: 610973) MAGUK p55 subfamily member 7 (576 aa) initn: 985 init1: 459 opt: 1230 Z-score: 858.1 bits: 168.9 E(85289): 4.7e-41 Smith-Waterman score: 1377; 39.8% identity (73.7% similar) in 575 aa overlap (126-674:16-574) 100 110 120 130 140 150 pF1KB9 KTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ .:...: . :::: ::...: .. NP_775 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQ--EDLTFLWDMFG 10 20 30 40 160 170 180 190 200 210 pF1KB9 NKDFQNAFKIHNAITVHMNKASPPFPLISNA----QDLAQEVQTVLKPVHHKEGQELTAL .:.... :::. . :. . . : :.. .: .:::.:.:. ::.. .: .:: : NP_775 EKSLHSLVKIHEKL--HYYEKQSPVPILHGAAALADDLAEELQN--KPLN-SEIRELLKL 50 60 70 80 90 220 230 240 250 260 270 pF1KB9 LNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV :. :...::: .:: ::.... .:. . :.: . ..:::.:. : :. :::::. NP_775 LSKPNVKALLSVHDTVAQKNY--DPVLPP-MPEDIDDEE-DSVKIIRLVKNRE-PLGATI 100 110 120 130 140 150 280 290 300 310 320 pF1KB9 RNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT ... .. .:..::..::::..:::.: :::. :.::: .. : .:....:.. .:..: NP_775 KKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAIT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB9 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW : .::... . :.:: . .:: :::.:..: .::.: ::::.:::::...::.: .: NP_775 FKIIPGSK-EETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATW 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB9 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------SG--KLWCAKKN ::: .:.: . : :::.:.: ::..: :... : .: : :: : . ... NP_775 WQAKHEADAN--PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRKSSGFRKSFRLSRK 280 290 300 310 320 450 460 470 480 490 500 pF1KB9 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQNCGQNELRQRLM :: .: .:. .:.:.::. .. ::::.. :.. .:.: : ..:.:: . : :::...:. NP_775 DKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLL 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB9 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSI .. .... .::::::.::.:: : .: :.:.. ::.:. .::::.::...: ::::: NP_775 ISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSI 390 400 410 420 430 440 570 580 590 600 610 pF1KB9 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA-------LLAKEG ::::.:. ..:.:::... ...: ::. ..:::.::: ::: :::: . ... NP_775 DSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDD 450 460 470 480 490 500 620 630 640 650 660 pF1KB9 KNP-KP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV .. :: :...:.:.... ::.. :: :: :.:.:: :..:: ..::.:: .:: NP_775 QGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWV 510 520 530 540 550 560 670 pF1KB9 PSTWLR : .:: NP_775 PVSWLHS 570 >>NP_001305099 (OMIM: 610973) MAGUK p55 subfamily member (576 aa) initn: 985 init1: 459 opt: 1230 Z-score: 858.1 bits: 168.9 E(85289): 4.7e-41 Smith-Waterman score: 1377; 39.8% identity (73.7% similar) in 575 aa overlap (126-674:16-574) 100 110 120 130 140 150 pF1KB9 KTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ .:...: . :::: ::...: .. NP_001 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQ--EDLTFLWDMFG 10 20 30 40 160 170 180 190 200 210 pF1KB9 NKDFQNAFKIHNAITVHMNKASPPFPLISNA----QDLAQEVQTVLKPVHHKEGQELTAL .:.... :::. . :. . . : :.. .: .:::.:.:. ::.. .: .:: : NP_001 EKSLHSLVKIHEKL--HYYEKQSPVPILHGAAALADDLAEELQN--KPLN-SEIRELLKL 50 60 70 80 90 220 230 240 250 260 270 pF1KB9 LNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV :. :...::: .:: ::.... .:. . :.: . ..:::.:. : :. :::::. NP_001 LSKPNVKALLSVHDTVAQKNY--DPVLPP-MPEDIDDEE-DSVKIIRLVKNRE-PLGATI 100 110 120 130 140 150 280 290 300 310 320 pF1KB9 RNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT ... .. .:..::..::::..:::.: :::. :.::: .. : .:....:.. .:..: NP_001 KKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAIT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB9 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW : .::... . :.:: . .:: :::.:..: .::.: ::::.:::::...::.: .: NP_001 FKIIPGSK-EETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATW 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB9 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------SG--KLWCAKKN ::: .:.: . : :::.:.: ::..: :... : .: : :: : . ... NP_001 WQAKHEADAN--PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRKSSGFRKSFRLSRK 280 290 300 310 320 450 460 470 480 490 500 pF1KB9 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQNCGQNELRQRLM :: .: .:. .:.:.::. .. ::::.. :.. .:.: : ..:.:: . : :::...:. NP_001 DKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLL 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB9 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSI .. .... .::::::.::.:: : .: :.:.. ::.:. .::::.::...: ::::: NP_001 ISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSI 390 400 410 420 430 440 570 580 590 600 610 pF1KB9 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA-------LLAKEG ::::.:. ..:.:::... ...: ::. ..:::.::: ::: :::: . ... NP_001 DSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDD 450 460 470 480 490 500 620 630 640 650 660 pF1KB9 KNP-KP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV .. :: :...:.:.... ::.. :: :: :.:.:: :..:: ..::.:: .:: NP_001 QGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWV 510 520 530 540 550 560 670 pF1KB9 PSTWLR : .:: NP_001 PVSWLHS 570 >>XP_011517639 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (576 aa) initn: 985 init1: 459 opt: 1230 Z-score: 858.1 bits: 168.9 E(85289): 4.7e-41 Smith-Waterman score: 1377; 39.8% identity (73.7% similar) in 575 aa overlap (126-674:16-574) 100 110 120 130 140 150 pF1KB9 KTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ .:...: . :::: ::...: .. XP_011 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQ--EDLTFLWDMFG 10 20 30 40 160 170 180 190 200 210 pF1KB9 NKDFQNAFKIHNAITVHMNKASPPFPLISNA----QDLAQEVQTVLKPVHHKEGQELTAL .:.... :::. . :. . . : :.. .: .:::.:.:. ::.. .: .:: : XP_011 EKSLHSLVKIHEKL--HYYEKQSPVPILHGAAALADDLAEELQN--KPLN-SEIRELLKL 50 60 70 80 90 220 230 240 250 260 270 pF1KB9 LNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV :. :...::: .:: ::.... .:. . :.: . ..:::.:. : :. :::::. XP_011 LSKPNVKALLSVHDTVAQKNY--DPVLPP-MPEDIDDEE-DSVKIIRLVKNRE-PLGATI 100 110 120 130 140 150 280 290 300 310 320 pF1KB9 RNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT ... .. .:..::..::::..:::.: :::. :.::: .. : .:....:.. .:..: XP_011 KKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAIT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB9 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW : .::... . :.:: . .:: :::.:..: .::.: ::::.:::::...::.: .: XP_011 FKIIPGSK-EETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATW 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB9 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------SG--KLWCAKKN ::: .:.: . : :::.:.: ::..: :... : .: : :: : . ... XP_011 WQAKHEADAN--PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRKSSGFRKSFRLSRK 280 290 300 310 320 450 460 470 480 490 500 pF1KB9 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQNCGQNELRQRLM :: .: .:. .:.:.::. .. ::::.. :.. .:.: : ..:.:: . : :::...:. XP_011 DKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLL 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB9 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSI .. .... .::::::.::.:: : .: :.:.. ::.:. .::::.::...: ::::: XP_011 ISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSI 390 400 410 420 430 440 570 580 590 600 610 pF1KB9 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA-------LLAKEG ::::.:. ..:.:::... ...: ::. ..:::.::: ::: :::: . ... XP_011 DSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDD 450 460 470 480 490 500 620 630 640 650 660 pF1KB9 KNP-KP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV .. :: :...:.:.... ::.. :: :: :.:.:: :..:: ..::.:: .:: XP_011 QGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWV 510 520 530 540 550 560 670 pF1KB9 PSTWLR : .:: XP_011 PVSWLHS 570 >>XP_016871231 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (574 aa) initn: 1106 init1: 459 opt: 1211 Z-score: 845.1 bits: 166.5 E(85289): 2.5e-40 Smith-Waterman score: 1358; 39.7% identity (73.6% similar) in 575 aa overlap (126-674:16-572) 100 110 120 130 140 150 pF1KB9 KTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ .:...: . :::: ::...: .. XP_016 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQ--EDLTFLWDMFG 10 20 30 40 160 170 180 190 200 210 pF1KB9 NKDFQNAFKIHNAITVHMNKASPPFPLISNA----QDLAQEVQTVLKPVHHKEGQELTAL .:.... ::. . :. . . : :.. .: .:::.:.:. ::.. .: .:: : XP_016 EKSLHSL--IHEKL--HYYEKQSPVPILHGAAALADDLAEELQN--KPLN-SEIRELLKL 50 60 70 80 90 220 230 240 250 260 270 pF1KB9 LNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV :. :...::: .:: ::.... .:. . :.: . ..:::.:. : :. :::::. XP_016 LSKPNVKALLSVHDTVAQKNY--DPVLPP-MPEDIDDEE-DSVKIIRLVKNRE-PLGATI 100 110 120 130 140 150 280 290 300 310 320 pF1KB9 RNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT ... .. .:..::..::::..:::.: :::. :.::: .. : .:....:.. .:..: XP_016 KKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAIT 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB9 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW : .::... . :.:: . .:: :::.:..: .::.: ::::.:::::...::.: .: XP_016 FKIIPGSK-EETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATW 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB9 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------SG--KLWCAKKN ::: .:.: . : :::.:.: ::..: :... : .: : :: : . ... XP_016 WQAKHEADAN--PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRKSSGFRKSFRLSRK 280 290 300 310 320 450 460 470 480 490 500 pF1KB9 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQNCGQNELRQRLM :: .: .:. .:.:.::. .. ::::.. :.. .:.: : ..:.:: . : :::...:. XP_016 DKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLL 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB9 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSI .. .... .::::::.::.:: : .: :.:.. ::.:. .::::.::...: ::::: XP_016 ISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSI 390 400 410 420 430 440 570 580 590 600 610 pF1KB9 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA-------LLAKEG ::::.:. ..:.:::... ...: ::. ..:::.::: ::: :::: . ... XP_016 DSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDD 450 460 470 480 490 500 620 630 640 650 660 pF1KB9 KNP-KP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV .. :: :...:.:.... ::.. :: :: :.:.:: :..:: ..::.:: .:: XP_016 QGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWV 510 520 530 540 550 560 670 pF1KB9 PSTWLR : .:: XP_016 PVSWLHS 570 >>XP_016871230 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (657 aa) initn: 959 init1: 459 opt: 1185 Z-score: 826.6 bits: 163.3 E(85289): 2.6e-39 Smith-Waterman score: 1332; 40.0% identity (73.3% similar) in 565 aa overlap (139-674:107-655) 110 120 130 140 150 160 pF1KB9 GIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLL---QLVQNKDFQNAFKI :... :. : : :: : .:. .. : XP_016 LKRLTKYTDLGRQRGCRLLNWNSLWLSEGRVSGERWADLFLHLASCQLCQ-RDLGVTL-I 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB9 HNAITVHMNKASPPFPLISNA----QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALL :. . :. . . : :.. .: .:::.:.:. ::.. .: .:: ::. :...::: XP_016 HEKL--HYYEKQSPVPILHGAAALADDLAEELQN--KPLN-SEIRELLKLLSKPNVKALL 140 150 160 170 180 230 240 250 260 270 pF1KB9 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS--VI .:: ::.... .:. . :.: . ..:::.:. : :. :::::.... .. .: XP_016 SVHDTVAQKNY--DPVLPP-MPEDIDDEE-DSVKIIRLVKNRE-PLGATIKKDEQTGAII 190 200 210 220 230 240 280 290 300 310 320 330 pF1KB9 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK ..::..::::..:::.: :::. :.::: .. : .:....:.. .:..:: .::... . XP_016 VARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSK-E 250 260 270 280 290 300 340 350 360 370 380 390 pF1KB9 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED :.:: . .:: :::.:..: .::.: ::::.:::::...::.: .:::: .:.: . XP_016 ETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADAN 310 320 330 340 350 360 400 410 420 430 440 450 pF1KB9 NQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------SG--KLWCAKKNKKKRKKVLYN : :::.:.: ::..: :... : .: : :: : . ... :: .: .:. XP_016 --PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYE 370 380 390 400 410 420 460 470 480 490 500 510 pF1KB9 ANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQNCGQNELRQRLMNKEKDRFASA .:.:.::. .. ::::.. :.. .:.: : ..:.:: . : :::...:. .. .... . XP_016 CKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVT 430 440 450 460 470 480 520 530 540 550 560 570 pF1KB9 VPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSG ::::::.::.:: : .: :.:.. ::.:. .::::.::...: :::::::::.:. .. XP_016 VPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKN 490 500 510 520 530 540 580 590 600 610 pF1KB9 KICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA-------LLAKEGKNP-KP---E :.:::... ...: ::. ..:::.::: ::: :::: . ... .. :: : XP_016 KVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEE 550 560 570 580 590 600 620 630 640 650 660 670 pF1KB9 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR ...:.:.... ::.. :: :: :.:.:: :..:: ..::.:: .::: .:: XP_016 DFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS 610 620 630 640 650 675 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:01:32 2016 done: Fri Nov 4 00:01:34 2016 Total Scan time: 11.690 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]