FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9501, 1120 aa 1>>>pF1KB9501 1120 - 1120 aa - 1120 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8150+/-0.000608; mu= 15.0225+/- 0.037 mean_var=246.7169+/-52.438, 0's: 0 Z-trim(111.0): 375 B-trim: 355 in 1/52 Lambda= 0.081653 statistics sampled from 19040 (19499) to 19040 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.229), width: 16 Scan time: 14.280 The best scores are: opt bits E(85289) NP_001241651 (OMIM: 160794,614335,614915) myosin-b (1120) 7508 900.3 0 NP_001241649 (OMIM: 160794,614335,614915) myosin-b (1134) 7456 894.1 0 NP_001241648 (OMIM: 160794,614335,614915) myosin-b (1146) 7456 894.2 0 NP_002456 (OMIM: 160794,614335,614915) myosin-bind (1171) 7456 894.2 0 NP_996557 (OMIM: 160794,614335,614915) myosin-bind (1123) 7284 873.9 0 NP_996555 (OMIM: 160794,614335,614915) myosin-bind (1148) 7284 873.9 0 XP_016874806 (OMIM: 160794,614335,614915) PREDICTE (1152) 7276 873.0 0 XP_006719471 (OMIM: 160794,614335,614915) PREDICTE (1177) 7276 873.0 0 NP_001241652 (OMIM: 160794,614335,614915) myosin-b (1139) 7275 872.8 0 XP_005268933 (OMIM: 160794,614335,614915) PREDICTE (1165) 7275 872.8 0 NP_001241650 (OMIM: 160794,614335,614915) myosin-b (1127) 6425 772.7 0 XP_016874807 (OMIM: 160794,614335,614915) PREDICTE (1152) 6395 769.2 0 XP_016874810 (OMIM: 160794,614335,614915) PREDICTE (1133) 6245 751.5 6.5e-216 XP_016874811 (OMIM: 160794,614335,614915) PREDICTE (1107) 6215 747.9 7.4e-215 XP_016874809 (OMIM: 160794,614335,614915) PREDICTE (1144) 4923 595.8 5e-169 NP_996556 (OMIM: 160794,614335,614915) myosin-bind (1141) 4871 589.6 3.5e-167 XP_006719474 (OMIM: 160794,614335,614915) PREDICTE (1164) 4871 589.6 3.5e-167 XP_006719473 (OMIM: 160794,614335,614915) PREDICTE (1166) 4871 589.6 3.5e-167 XP_006719472 (OMIM: 160794,614335,614915) PREDICTE (1170) 4871 589.7 3.5e-167 NP_001241647 (OMIM: 160794,614335,614915) myosin-b (1173) 4871 589.7 3.5e-167 XP_016874805 (OMIM: 160794,614335,614915) PREDICTE (1173) 4871 589.7 3.5e-167 XP_006719469 (OMIM: 160794,614335,614915) PREDICTE (1189) 4871 589.7 3.5e-167 XP_006719468 (OMIM: 160794,614335,614915) PREDICTE (1195) 4871 589.7 3.6e-167 XP_006719470 (OMIM: 160794,614335,614915) PREDICTE (1183) 4870 589.5 3.8e-167 XP_016874808 (OMIM: 160794,614335,614915) PREDICTE (1151) 3840 468.2 1.3e-130 XP_016874804 (OMIM: 160794,614335,614915) PREDICTE (1176) 3810 464.7 1.5e-129 NP_004524 (OMIM: 160793) myosin-binding protein C, (1141) 2411 299.8 6e-80 NP_000247 (OMIM: 115197,600958,615396) myosin-bind (1274) 2231 278.7 1.5e-73 NP_004988 (OMIM: 160795) myosin-binding protein H ( 477) 1539 196.6 3.1e-49 NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 1068 143.7 1.5e-31 XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 1068 143.7 1.5e-31 NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 1068 143.7 1.5e-31 NP_597681 (OMIM: 188840,600334,603689,604145,60880 (27118) 1068 143.7 1.5e-31 XP_016860311 (OMIM: 188840,600334,603689,604145,60 (33101) 1068 143.8 1.6e-31 NP_596869 (OMIM: 188840,600334,603689,604145,60880 (33423) 1068 143.8 1.6e-31 XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 1068 143.8 1.7e-31 XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 1068 143.8 1.7e-31 NP_001243779 (OMIM: 188840,600334,603689,604145,60 (34350) 1068 143.8 1.7e-31 XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 1068 143.8 1.7e-31 NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 1068 143.8 1.7e-31 NP_443075 (OMIM: 608616) obscurin isoform a [Homo (6620) 474 72.8 7.8e-11 XP_006711892 (OMIM: 608616) PREDICTED: obscurin is (6865) 474 72.8 7.9e-11 XP_006711890 (OMIM: 608616) PREDICTED: obscurin is (6957) 474 72.8 8e-11 XP_016857962 (OMIM: 608616) PREDICTED: obscurin is (7362) 474 72.9 8.2e-11 XP_016857961 (OMIM: 608616) PREDICTED: obscurin is (7692) 474 72.9 8.4e-11 XP_016857960 (OMIM: 608616) PREDICTED: obscurin is (7693) 474 72.9 8.4e-11 NP_001092093 (OMIM: 608616) obscurin isoform b [Ho (7968) 474 72.9 8.6e-11 XP_016857959 (OMIM: 608616) PREDICTED: obscurin is (8074) 474 72.9 8.7e-11 XP_011542601 (OMIM: 608616) PREDICTED: obscurin is (8213) 474 72.9 8.7e-11 XP_011542599 (OMIM: 608616) PREDICTED: obscurin is (8305) 474 72.9 8.8e-11 >>NP_001241651 (OMIM: 160794,614335,614915) myosin-bindi (1120 aa) initn: 7508 init1: 7508 opt: 7508 Z-score: 4801.4 bits: 900.3 E(85289): 0 Smith-Waterman score: 7508; 100.0% identity (100.0% similar) in 1120 aa overlap (1-1120:1-1120) 10 20 30 40 50 60 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 QVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 GKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KB9 LGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLHNKDF :::::::::::::::::::::::::::::::::::::::: NP_001 LGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLHNKDF 1090 1100 1110 1120 >>NP_001241649 (OMIM: 160794,614335,614915) myosin-bindi (1134 aa) initn: 7456 init1: 7456 opt: 7456 Z-score: 4768.3 bits: 894.1 E(85289): 0 Smith-Waterman score: 7470; 98.8% identity (98.8% similar) in 1134 aa overlap (1-1120:1-1134) 10 20 30 40 pF1KB9 MPEPTKKE--------------DWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVG :::::::: :::::::::::::::::::::::::::::::::::::: NP_001 MPEPTKKEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 EDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 KDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANV 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 LKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB9 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB9 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB9 KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB9 LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB9 TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB9 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB9 LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB9 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KB9 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KB9 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KB9 PYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLHNKDF :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLHNKDF 1090 1100 1110 1120 1130 >>NP_001241648 (OMIM: 160794,614335,614915) myosin-bindi (1146 aa) initn: 7456 init1: 7456 opt: 7456 Z-score: 4768.2 bits: 894.2 E(85289): 0 Smith-Waterman score: 7456; 99.7% identity (99.8% similar) in 1116 aa overlap (5-1120:31-1146) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILF : .:::::::::::::::::::::::::: NP_001 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB9 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB9 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 790 800 810 820 830 840 820 830 840 850 860 870 pF1KB9 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 850 860 870 880 890 900 880 890 900 910 920 930 pF1KB9 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 910 920 930 940 950 960 940 950 960 970 980 990 pF1KB9 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KB9 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KB9 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQS 1090 1100 1110 1120 1130 1140 1120 pF1KB9 LHNKDF :::::: NP_001 LHNKDF >>NP_002456 (OMIM: 160794,614335,614915) myosin-binding (1171 aa) initn: 7456 init1: 7456 opt: 7456 Z-score: 4768.1 bits: 894.2 E(85289): 0 Smith-Waterman score: 7456; 99.8% identity (99.8% similar) in 1115 aa overlap (6-1120:57-1171) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILFI : ::::::::::::::::::::::::::: NP_002 EAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQAKQNANSQLSILFI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB9 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB9 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB9 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB9 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 510 520 530 540 550 560 520 530 540 550 560 570 pF1KB9 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KB9 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KB9 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP 690 700 710 720 730 740 700 710 720 730 740 750 pF1KB9 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG 750 760 770 780 790 800 760 770 780 790 800 810 pF1KB9 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KB9 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV 870 880 890 900 910 920 880 890 900 910 920 930 pF1KB9 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 930 940 950 960 970 980 940 950 960 970 980 990 pF1KB9 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KB9 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KB9 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSL 1110 1120 1130 1140 1150 1160 1120 pF1KB9 HNKDF ::::: NP_002 HNKDF 1170 >>NP_996557 (OMIM: 160794,614335,614915) myosin-binding (1123 aa) initn: 7584 init1: 7280 opt: 7284 Z-score: 4658.8 bits: 873.9 E(85289): 0 Smith-Waterman score: 7284; 99.6% identity (99.7% similar) in 1093 aa overlap (5-1097:31-1123) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILF : .:::::::::::::::::::::::::: NP_996 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB9 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB9 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 790 800 810 820 830 840 820 830 840 850 860 870 pF1KB9 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 850 860 870 880 890 900 880 890 900 910 920 930 pF1KB9 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 910 920 930 940 950 960 940 950 960 970 980 990 pF1KB9 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KB9 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KB9 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQS ::::::::::::::::::::::::::::::::::::::::: : NP_996 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1090 1100 1110 1120 1120 pF1KB9 LHNKDF >>NP_996555 (OMIM: 160794,614335,614915) myosin-binding (1148 aa) initn: 7578 init1: 7280 opt: 7284 Z-score: 4658.7 bits: 873.9 E(85289): 0 Smith-Waterman score: 7284; 99.7% identity (99.7% similar) in 1092 aa overlap (6-1097:57-1148) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILFI : ::::::::::::::::::::::::::: NP_996 EAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQAKQNANSQLSILFI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB9 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB9 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB9 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB9 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 510 520 530 540 550 560 520 530 540 550 560 570 pF1KB9 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KB9 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KB9 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP 690 700 710 720 730 740 700 710 720 730 740 750 pF1KB9 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG 750 760 770 780 790 800 760 770 780 790 800 810 pF1KB9 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KB9 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV 870 880 890 900 910 920 880 890 900 910 920 930 pF1KB9 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 930 940 950 960 970 980 940 950 960 970 980 990 pF1KB9 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KB9 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KB9 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSL :::::::::::::::::::::::::::::::::::::::: : NP_996 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1110 1120 1130 1140 1120 pF1KB9 HNKDF >>XP_016874806 (OMIM: 160794,614335,614915) PREDICTED: m (1152 aa) initn: 7269 init1: 7269 opt: 7276 Z-score: 4653.6 bits: 873.0 E(85289): 0 Smith-Waterman score: 7276; 97.4% identity (98.5% similar) in 1122 aa overlap (5-1119:31-1148) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILF : .:::::::::::::::::::::::::: XP_016 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB9 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB9 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 790 800 810 820 830 840 820 830 840 850 860 870 pF1KB9 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 850 860 870 880 890 900 880 890 900 910 920 930 pF1KB9 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 910 920 930 940 950 960 940 950 960 970 980 990 pF1KB9 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KB9 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 pF1KB9 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK-------VIYQGVNTPGQPVF ::::::::::::::::::::::::::::::::::::::: .. ::: : : . XP_016 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGV--P--PNI 1090 1100 1110 1120 1130 1110 1120 pF1KB9 LEGQQQSLHNKDF ... ..::... XP_016 IDSYLRDLHSSNPEEY 1140 1150 >>XP_006719471 (OMIM: 160794,614335,614915) PREDICTED: m (1177 aa) initn: 7269 init1: 7269 opt: 7276 Z-score: 4653.5 bits: 873.0 E(85289): 0 Smith-Waterman score: 7276; 97.5% identity (98.5% similar) in 1121 aa overlap (6-1119:57-1173) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLSILFI : ::::::::::::::::::::::::::: XP_006 EAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQAKQNANSQLSILFI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSR 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEG 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB9 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFE 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB9 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVEL 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQ 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB9 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVH 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB9 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 510 520 530 540 550 560 520 530 540 550 560 570 pF1KB9 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KB9 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KB9 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP 690 700 710 720 730 740 700 710 720 730 740 750 pF1KB9 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG 750 760 770 780 790 800 760 770 780 790 800 810 pF1KB9 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KB9 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV 870 880 890 900 910 920 880 890 900 910 920 930 pF1KB9 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 930 940 950 960 970 980 940 950 960 970 980 990 pF1KB9 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KB9 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 pF1KB9 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK-------VIYQGVNTPGQPVFL :::::::::::::::::::::::::::::::::::::: .. ::: : : .. XP_006 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGV--P--PNII 1110 1120 1130 1140 1150 1160 1110 1120 pF1KB9 EGQQQSLHNKDF .. ..::... XP_006 DSYLRDLHSSNPEEY 1170 >>NP_001241652 (OMIM: 160794,614335,614915) myosin-bindi (1139 aa) initn: 7265 init1: 7265 opt: 7275 Z-score: 4653.0 bits: 872.8 E(85289): 0 Smith-Waterman score: 7292; 96.6% identity (97.5% similar) in 1139 aa overlap (1-1119:1-1135) 10 20 30 40 pF1KB9 MPEPTKKED-------------WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGE ::::::::: :::::::::::::::::::::::::::::::::::::: NP_001 MPEPTKKEDEEEVSPPSALPPDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 DITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 DNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 LKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 FAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 KILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANA 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB9 LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB9 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB9 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB9 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB9 VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB9 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB9 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB9 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KB9 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KB9 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KB9 YDGGTYCCKAVNDLGTVEIECKLEVK-------VIYQGVNTPGQPVFLEGQQQSLHNKDF :::::::::::::::::::::::::: .. ::: : : .... ..::... NP_001 YDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGV--P--PNIIDSYLRDLHSSNP 1090 1100 1110 1120 1130 NP_001 EEY >>XP_005268933 (OMIM: 160794,614335,614915) PREDICTED: m (1165 aa) initn: 7309 init1: 7265 opt: 7275 Z-score: 4652.9 bits: 872.8 E(85289): 0 Smith-Waterman score: 7275; 97.2% identity (98.2% similar) in 1125 aa overlap (2-1119:41-1161) 10 20 30 pF1KB9 MPEPTKKEDWTLVETPPGEEQAKQNANSQLS : . ::::::::::::::::::::::: XP_005 EVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPDWTLVETPPGEEQAKQNANSQLS 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 RHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKR 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB9 SGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGM 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTK 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB9 YIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGE 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB9 RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMT 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB9 TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRL 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB9 KVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB9 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 560 570 580 590 600 610 580 590 600 610 620 630 pF1KB9 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 620 630 640 650 660 670 640 650 660 670 680 690 pF1KB9 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 680 690 700 710 720 730 700 710 720 730 740 750 pF1KB9 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 740 750 760 770 780 790 760 770 780 790 800 810 pF1KB9 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 800 810 820 830 840 850 820 830 840 850 860 870 pF1KB9 AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 860 870 880 890 900 910 880 890 900 910 920 930 pF1KB9 DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 920 930 940 950 960 970 940 950 960 970 980 990 pF1KB9 MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKN 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KB9 PVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM 1040 1050 1060 1070 1080 1090 1060 1070 1080 1090 1100 pF1KB9 FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK-------VIYQGVNTPGQ :::::::::::::::::::::::::::::::::::::::::: .. ::: : XP_005 FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGV--P-- 1100 1110 1120 1130 1140 1110 1120 pF1KB9 PVFLEGQQQSLHNKDF : .... ..::... XP_005 PNIIDSYLRDLHSSNPEEY 1150 1160 1120 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:02:20 2016 done: Fri Nov 4 00:02:22 2016 Total Scan time: 14.280 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]