FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9502, 1173 aa 1>>>pF1KB9502 1173 - 1173 aa - 1173 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0999+/-0.000401; mu= 4.9381+/- 0.025 mean_var=202.5884+/-41.127, 0's: 0 Z-trim(118.5): 18 B-trim: 71 in 2/49 Lambda= 0.090109 statistics sampled from 31600 (31616) to 31600 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.371), width: 16 Scan time: 17.920 The best scores are: opt bits E(85289) NP_060591 (OMIM: 610348) SMC5-SMC6 complex localiz (1173) 7749 1021.0 0 XP_005270022 (OMIM: 610348) PREDICTED: SMC5-SMC6 c (1172) 7732 1018.8 0 NP_001129595 (OMIM: 610348) SMC5-SMC6 complex loca (1186) 7660 1009.5 0 XP_011538246 (OMIM: 610348) PREDICTED: SMC5-SMC6 c (1109) 7286 960.8 0 NP_001230699 (OMIM: 610348) SMC5-SMC6 complex loca ( 63) 347 58.0 2.2e-08 >>NP_060591 (OMIM: 610348) SMC5-SMC6 complex localizatio (1173 aa) initn: 7749 init1: 7749 opt: 7749 Z-score: 5453.3 bits: 1021.0 E(85289): 0 Smith-Waterman score: 7749; 99.9% identity (99.9% similar) in 1173 aa overlap (1-1173:1-1173) 10 20 30 40 50 60 pF1KB9 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 YGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS ::::::::::::::::::::::::::::::::: NP_060 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS 1150 1160 1170 >>XP_005270022 (OMIM: 610348) PREDICTED: SMC5-SMC6 compl (1172 aa) initn: 5592 init1: 5592 opt: 7732 Z-score: 5441.4 bits: 1018.8 E(85289): 0 Smith-Waterman score: 7732; 99.8% identity (99.8% similar) in 1173 aa overlap (1-1173:1-1172) 10 20 30 40 50 60 pF1KB9 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: XP_005 NLSNVENGHLSRKRSSSDSWEPTS-GSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 YGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB9 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB9 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB9 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB9 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB9 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB9 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1080 1090 1100 1110 1120 1130 1150 1160 1170 pF1KB9 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS ::::::::::::::::::::::::::::::::: XP_005 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS 1140 1150 1160 1170 >>NP_001129595 (OMIM: 610348) SMC5-SMC6 complex localiza (1186 aa) initn: 7660 init1: 7660 opt: 7660 Z-score: 5390.7 bits: 1009.5 E(85289): 0 Smith-Waterman score: 7660; 99.9% identity (99.9% similar) in 1162 aa overlap (1-1162:1-1162) 10 20 30 40 50 60 pF1KB9 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSSYHLPKEMKSLKKKHRSPERRKSLFIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSRSLSSRSSLSRHHPEESPLGAKFQLSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASYCRERELKRLRKEQMEQRINSENSFSEASSLSLKSSIERKYKPRQEQRKQNDIIPGKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPSDETDGSSAGLAPSNSGNSGHHST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 YGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSGNSNAGSSALKRKLRGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPAATGKPPALSKGLRSQSSDYTGHV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKV 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 KDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS :::::::::::::::::::::: NP_001 KDLVARIHGKWQEIIQNCRPTQVSFCYTISCILNSFAEWHSSYCLK 1150 1160 1170 1180 >>XP_011538246 (OMIM: 610348) PREDICTED: SMC5-SMC6 compl (1109 aa) initn: 7286 init1: 7286 opt: 7286 Z-score: 5128.4 bits: 960.8 E(85289): 0 Smith-Waterman score: 7286; 99.9% identity (99.9% similar) in 1109 aa overlap (65-1173:1-1109) 40 50 60 70 80 90 pF1KB9 AAAGKRTESPGDRKQSIIDFFKPASKQDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLS :::::::::::::::::::::::::::::: XP_011 MLDSPQKSNIKYGGSRLSITGTEQFERKLS 10 20 30 100 110 120 130 140 150 pF1KB9 SPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPKESKPKRVPPEKSPIIEAFMKGVKEHHEDHGIHESRRPCLSLASKYLAKGTNIYVPSS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 YHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YHLPKEMKSLKKKHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFNNSSR 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 SLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSSRSSLSRHHPEESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASSLS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB9 LKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKSSIERKYKPRQEQRKQNDIIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPE 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB9 KRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB9 EPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPSDETDGSSAGLAPSNSGNSGHHSTRNSDQIQVAGTKETKMQKPHLPLSQEKSAIKKAS 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB9 NLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGH 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB9 STESTKHKEHKAKTNKADSNVSSGKIYGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 STESTKHKEHKAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSD 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB9 KAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAPSEGESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQ 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB9 TPAATGKPPALSKGLRSQSSDYTGHVHPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPAATGKPPALSKGLRSQSSDYTGHVHPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIR 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB9 QGRGIKSPIRIGEEDSTDDEDGLLEEHKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGRGIKSPIRIGEEDSTDDEDGLLEEHKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIF 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB9 NQYTLDLRDSGFIGQSAVEKLILKSGKTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NQYTLDLRDSGFIGQSAVEKLILKSGKTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMM 700 710 720 730 740 750 820 830 840 850 860 870 pF1KB9 SVHTDCIVSVQILSTLMEITIRNDTFSDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVHTDCIVSVQILSTLMEITIRNDTFSDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLEN 760 770 780 790 800 810 880 890 900 910 920 930 pF1KB9 LQPDFNEDYLVSETQTTSRGKESEDSSYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPDFNEDYLVSETQTTSRGKESEDSSYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQD 820 830 840 850 860 870 940 950 960 970 980 990 pF1KB9 REIMLLILMLFKMSLEKQLKQIPLVDFQSLLINLMKNIRDWNTKVPELCLGINELSSHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REIMLLILMLFKMSLEKQLKQIPLVDFQSLLINLMKNIRDWNTKVPELCLGINELSSHPH 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KB9 NLLWLVQLVPNWTSRGRQLRQCLSLVIISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLLWLVQLVPNWTSRGRQLRQCLSLVIISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPS 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KB9 DLLKKMVLKKKAEQPDGIIDDSLHLELEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLKKMVLKKKAEQPDGIIDDSLHLELEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFV 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KB9 LLCGALEKHVKCDIREDARLFYRTKVKDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLCGALEKHVKCDIREDARLFYRTKVKDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS 1060 1070 1080 1090 1100 >>NP_001230699 (OMIM: 610348) SMC5-SMC6 complex localiza (63 aa) initn: 369 init1: 347 opt: 347 Z-score: 271.6 bits: 58.0 E(85289): 2.2e-08 Smith-Waterman score: 347; 100.0% identity (100.0% similar) in 47 aa overlap (1-47:1-47) 10 20 30 40 50 60 pF1KB9 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASK ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRYRAEGLRRGRVAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QDRHMLDSPQKSNIKYGGSRLSITGTEQFERKLSSPKESKPKRVPPEKSPIIEAFMKGVK NP_001 ARV 1173 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:03:16 2016 done: Fri Nov 4 00:03:18 2016 Total Scan time: 17.920 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]