Result of FASTA (omim) for
pF1KB9504
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9504, 1314 aa
1>>>pF1KB9504 1314 - 1314 aa - 1314 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8883+/-0.000443; mu= 21.4745+/- 0.028
mean_var=127.5320+/-27.245, 0's: 0 Z-trim(114.3): 93 B-trim: 1114 in 1/51
Lambda= 0.113570
statistics sampled from 24008 (24106) to 24008 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.283), width: 16
Scan time: 16.600
The best scores are: opt bits E(85289)
XP_011532297 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 8747 1446.1 0
XP_016862507 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 8747 1446.1 0
NP_071347 (OMIM: 614472) E3 ubiquitin-protein liga (1314) 8747 1446.1 0
XP_006713348 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 8747 1446.1 0
XP_016879333 (OMIM: 616585,616723) PREDICTED: RING ( 452) 320 64.8 1.5e-09
NP_001292092 (OMIM: 616585,616723) RING finger and ( 576) 320 65.0 1.8e-09
XP_005256277 (OMIM: 616585,616723) PREDICTED: RING ( 576) 320 65.0 1.8e-09
NP_588609 (OMIM: 616585,616723) RING finger and SP ( 576) 320 65.0 1.8e-09
NP_001292093 (OMIM: 616585,616723) RING finger and ( 576) 320 65.0 1.8e-09
XP_011521730 (OMIM: 616585,616723) PREDICTED: RING ( 607) 320 65.0 1.9e-09
XP_011521729 (OMIM: 616585,616723) PREDICTED: RING ( 607) 320 65.0 1.9e-09
XP_011521732 (OMIM: 616585,616723) PREDICTED: RING ( 607) 320 65.0 1.9e-09
XP_006711872 (OMIM: 180902,600996,604772) PREDICTE (2735) 291 61.0 1.4e-07
NP_004930 (OMIM: 601257) ATP-dependent RNA helicas ( 740) 282 58.9 1.6e-07
XP_006711871 (OMIM: 180902,600996,604772) PREDICTE (4906) 291 61.2 2e-07
XP_006711873 (OMIM: 180902,600996,604772) PREDICTE (4954) 291 61.2 2e-07
XP_006711870 (OMIM: 180902,600996,604772) PREDICTE (4965) 291 61.2 2e-07
NP_001026 (OMIM: 180902,600996,604772) ryanodine r (4967) 291 61.2 2e-07
XP_006711869 (OMIM: 180902,600996,604772) PREDICTE (4973) 291 61.2 2e-07
XP_006711868 (OMIM: 180902,600996,604772) PREDICTE (4975) 291 61.2 2e-07
XP_006711867 (OMIM: 180902,600996,604772) PREDICTE (4977) 291 61.2 2e-07
XP_016857517 (OMIM: 180902,600996,604772) PREDICTE (4978) 291 61.2 2e-07
XP_006711866 (OMIM: 180902,600996,604772) PREDICTE (4984) 291 61.2 2e-07
XP_006711865 (OMIM: 180902,600996,604772) PREDICTE (4985) 291 61.2 2e-07
XP_016877966 (OMIM: 180903) PREDICTED: ryanodine r (3855) 270 57.7 1.9e-06
XP_016877965 (OMIM: 180903) PREDICTED: ryanodine r (4830) 270 57.8 2.2e-06
XP_016877964 (OMIM: 180903) PREDICTED: ryanodine r (4837) 270 57.8 2.2e-06
XP_011520182 (OMIM: 180903) PREDICTED: ryanodine r (4859) 270 57.8 2.2e-06
XP_016877963 (OMIM: 180903) PREDICTED: ryanodine r (4859) 270 57.8 2.2e-06
XP_016877962 (OMIM: 180903) PREDICTED: ryanodine r (4860) 270 57.8 2.2e-06
XP_016877961 (OMIM: 180903) PREDICTED: ryanodine r (4864) 270 57.8 2.2e-06
NP_001230925 (OMIM: 180903) ryanodine receptor 3 i (4865) 270 57.8 2.2e-06
XP_016877958 (OMIM: 180903) PREDICTED: ryanodine r (4865) 270 57.8 2.2e-06
XP_016877960 (OMIM: 180903) PREDICTED: ryanodine r (4865) 270 57.8 2.2e-06
XP_016877959 (OMIM: 180903) PREDICTED: ryanodine r (4865) 270 57.8 2.2e-06
XP_016877957 (OMIM: 180903) PREDICTED: ryanodine r (4866) 270 57.8 2.2e-06
NP_001027 (OMIM: 180903) ryanodine receptor 3 isof (4870) 270 57.8 2.2e-06
XP_011525507 (OMIM: 117000,145600,180901,255310,25 (5009) 250 54.5 2.2e-05
XP_006723382 (OMIM: 117000,145600,180901,255310,25 (5027) 250 54.5 2.2e-05
XP_006723380 (OMIM: 117000,145600,180901,255310,25 (5032) 250 54.5 2.2e-05
NP_001036188 (OMIM: 117000,145600,180901,255310,25 (5033) 250 54.5 2.2e-05
NP_000531 (OMIM: 117000,145600,180901,255310,25532 (5038) 250 54.5 2.2e-05
NP_653333 (OMIM: 605800) heterogeneous nuclear rib ( 756) 208 46.7 0.00072
NP_001308137 (OMIM: 605800) heterogeneous nuclear ( 756) 208 46.7 0.00072
NP_001308140 (OMIM: 605800) heterogeneous nuclear ( 756) 208 46.7 0.00072
XP_011524695 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 208 46.8 0.00072
XP_011524696 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 208 46.8 0.00072
XP_011524697 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 208 46.8 0.00072
XP_005258521 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 208 46.8 0.00072
XP_005258520 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 208 46.8 0.00072
>>XP_011532297 (OMIM: 614472) PREDICTED: E3 ubiquitin-pr (1314 aa)
initn: 8747 init1: 8747 opt: 8747 Z-score: 7748.9 bits: 1446.1 E(85289): 0
Smith-Waterman score: 8747; 99.9% identity (100.0% similar) in 1314 aa overlap (1-1314:1-1314)
10 20 30 40 50 60
pF1KB9 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 DLQRLGGLLSHLRKTLKDDFASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_011 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KB9 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
1270 1280 1290 1300 1310
>>XP_016862507 (OMIM: 614472) PREDICTED: E3 ubiquitin-pr (1314 aa)
initn: 8747 init1: 8747 opt: 8747 Z-score: 7748.9 bits: 1446.1 E(85289): 0
Smith-Waterman score: 8747; 99.9% identity (100.0% similar) in 1314 aa overlap (1-1314:1-1314)
10 20 30 40 50 60
pF1KB9 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 DLQRLGGLLSHLRKTLKDDFASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KB9 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
1270 1280 1290 1300 1310
>>NP_071347 (OMIM: 614472) E3 ubiquitin-protein ligase R (1314 aa)
initn: 8747 init1: 8747 opt: 8747 Z-score: 7748.9 bits: 1446.1 E(85289): 0
Smith-Waterman score: 8747; 99.9% identity (100.0% similar) in 1314 aa overlap (1-1314:1-1314)
10 20 30 40 50 60
pF1KB9 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 DLQRLGGLLSHLRKTLKDDFASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_071 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KB9 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
1270 1280 1290 1300 1310
>>XP_006713348 (OMIM: 614472) PREDICTED: E3 ubiquitin-pr (1314 aa)
initn: 8747 init1: 8747 opt: 8747 Z-score: 7748.9 bits: 1446.1 E(85289): 0
Smith-Waterman score: 8747; 99.9% identity (100.0% similar) in 1314 aa overlap (1-1314:1-1314)
10 20 30 40 50 60
pF1KB9 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 DLQRLGGLLSHLRKTLKDDFASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_006 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KB9 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
1270 1280 1290 1300 1310
>>XP_016879333 (OMIM: 616585,616723) PREDICTED: RING fin (452 aa)
initn: 269 init1: 133 opt: 320 Z-score: 292.3 bits: 64.8 E(85289): 1.5e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:221-362)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
XP_016 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
200 210 220 230 240 250
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
XP_016 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
260 270 280 290 300 310
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
XP_016 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
320 330 340 350 360
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
XP_016 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
370 380 390 400 410 420
>>NP_001292092 (OMIM: 616585,616723) RING finger and SPR (576 aa)
initn: 269 init1: 133 opt: 320 Z-score: 291.1 bits: 65.0 E(85289): 1.8e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:345-486)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
NP_001 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
320 330 340 350 360 370
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
NP_001 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
380 390 400 410 420 430
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
NP_001 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
440 450 460 470 480 490
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
NP_001 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
500 510 520 530 540 550
>>XP_005256277 (OMIM: 616585,616723) PREDICTED: RING fin (576 aa)
initn: 269 init1: 133 opt: 320 Z-score: 291.1 bits: 65.0 E(85289): 1.8e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:345-486)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
XP_005 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
320 330 340 350 360 370
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
XP_005 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
380 390 400 410 420 430
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
XP_005 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
440 450 460 470 480 490
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
XP_005 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
500 510 520 530 540 550
>>NP_588609 (OMIM: 616585,616723) RING finger and SPRY d (576 aa)
initn: 269 init1: 133 opt: 320 Z-score: 291.1 bits: 65.0 E(85289): 1.8e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:345-486)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
NP_588 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
320 330 340 350 360 370
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
NP_588 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
380 390 400 410 420 430
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
NP_588 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
440 450 460 470 480 490
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
NP_588 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
500 510 520 530 540 550
>>NP_001292093 (OMIM: 616585,616723) RING finger and SPR (576 aa)
initn: 269 init1: 133 opt: 320 Z-score: 291.1 bits: 65.0 E(85289): 1.8e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:345-486)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
NP_001 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
320 330 340 350 360 370
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
NP_001 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
380 390 400 410 420 430
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
NP_001 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
440 450 460 470 480 490
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
NP_001 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
500 510 520 530 540 550
>>XP_011521730 (OMIM: 616585,616723) PREDICTED: RING fin (607 aa)
initn: 269 init1: 133 opt: 320 Z-score: 290.8 bits: 65.0 E(85289): 1.9e-09
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (119-257:376-517)
90 100 110 120 130 140
pF1KB9 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
:.: ..: : :: : : ::: . ..:.::
XP_011 LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
350 360 370 380 390 400
150 160 170 180 190 200
pF1KB9 IGWCTISCRFNQEEG--VGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
::: : . .: ..:: .:: . : :::: : : :. . . : :: :. :.::
XP_011 IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
410 420 430 440 450 460
210 220 230 240 250 260
pF1KB9 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
.. . : ::: .: . .: .. ..: : :. .. ::::..:..::
XP_011 NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
470 480 490 500 510 520
270 280 290 300 310 320
pF1KB9 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
XP_011 FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
530 540 550 560 570 580
1314 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:05:01 2016 done: Fri Nov 4 00:05:04 2016
Total Scan time: 16.600 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]