FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9509, 360 aa 1>>>pF1KB9509 360 - 360 aa - 360 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5173+/-0.00131; mu= 7.2376+/- 0.079 mean_var=160.7372+/-33.070, 0's: 0 Z-trim(105.2): 135 B-trim: 4 in 1/49 Lambda= 0.101162 statistics sampled from 8138 (8274) to 8138 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.254), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS2546.1 PPP1R7 gene_id:5510|Hs108|chr2 ( 360) 2266 343.0 2.4e-94 CCDS63194.1 PPP1R7 gene_id:5510|Hs108|chr2 ( 317) 1899 289.4 2.9e-78 CCDS63192.1 PPP1R7 gene_id:5510|Hs108|chr2 ( 280) 1702 260.6 1.2e-69 CCDS63193.1 PPP1R7 gene_id:5510|Hs108|chr2 ( 237) 1335 207.0 1.4e-53 CCDS63190.1 PPP1R7 gene_id:5510|Hs108|chr2 ( 221) 1315 204.0 9.9e-53 CCDS58376.1 LRRC49 gene_id:54839|Hs108|chr15 ( 691) 379 67.8 3.1e-11 CCDS55971.1 LRRC49 gene_id:54839|Hs108|chr15 ( 642) 372 66.8 6e-11 CCDS61694.1 LRRC49 gene_id:54839|Hs108|chr15 ( 676) 372 66.8 6.2e-11 CCDS32282.1 LRRC49 gene_id:54839|Hs108|chr15 ( 686) 372 66.8 6.3e-11 >>CCDS2546.1 PPP1R7 gene_id:5510|Hs108|chr2 (360 aa) initn: 2266 init1: 2266 opt: 2266 Z-score: 1807.4 bits: 343.0 E(32554): 2.4e-94 Smith-Waterman score: 2266; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB9 MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF 310 320 330 340 350 360 >>CCDS63194.1 PPP1R7 gene_id:5510|Hs108|chr2 (317 aa) initn: 1885 init1: 1885 opt: 1899 Z-score: 1518.7 bits: 289.4 E(32554): 2.9e-78 Smith-Waterman score: 1899; 97.7% identity (99.4% similar) in 310 aa overlap (51-360:8-317) 30 40 50 60 70 80 pF1KB9 RVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAED :.....: ::::::::::::::::::::: CCDS63 MAAERGAGQQQSQEMMEEEHELPVDMETINLDRDAED 10 20 30 90 100 110 120 130 140 pF1KB9 VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 HNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGA 220 230 240 250 260 270 330 340 350 360 pF1KB9 RSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF :::::::::::::::::::::::::::::::::::::::: CCDS63 RSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF 280 290 300 310 >>CCDS63192.1 PPP1R7 gene_id:5510|Hs108|chr2 (280 aa) initn: 1702 init1: 1702 opt: 1702 Z-score: 1364.0 bits: 260.6 E(32554): 1.2e-69 Smith-Waterman score: 1702; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KB9 MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE ::::::::::::::::::::::::::::::::: CCDS63 RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNVQDSLTY 250 260 270 280 310 320 330 340 350 360 pF1KB9 FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF >>CCDS63193.1 PPP1R7 gene_id:5510|Hs108|chr2 (237 aa) initn: 1321 init1: 1321 opt: 1335 Z-score: 1075.5 bits: 207.0 E(32554): 1.4e-53 Smith-Waterman score: 1335; 96.9% identity (99.1% similar) in 223 aa overlap (51-273:8-230) 30 40 50 60 70 80 pF1KB9 RVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAED :.....: ::::::::::::::::::::: CCDS63 MAAERGAGQQQSQEMMEEEHELPVDMETINLDRDAED 10 20 30 90 100 110 120 130 140 pF1KB9 VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 HNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGA ::::::::::::: CCDS63 HNGIEVIEGLENNVQDSLTY 220 230 >>CCDS63190.1 PPP1R7 gene_id:5510|Hs108|chr2 (221 aa) initn: 1315 init1: 1315 opt: 1315 Z-score: 1060.2 bits: 204.0 E(32554): 9.9e-53 Smith-Waterman score: 1315; 100.0% identity (100.0% similar) in 213 aa overlap (61-273:2-214) 40 50 60 70 80 90 pF1KB9 EGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGK :::::::::::::::::::::::::::::: CCDS63 MEEHELPVDMETINLDRDAEDVDLNHYRIGK 10 20 30 100 110 120 130 140 150 pF1KB9 IEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDIS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 FNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB9 ENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLER ::: CCDS63 ENNVQDSLTY 220 >>CCDS58376.1 LRRC49 gene_id:54839|Hs108|chr15 (691 aa) initn: 605 init1: 334 opt: 379 Z-score: 315.1 bits: 67.8 E(32554): 3.1e-11 Smith-Waterman score: 379; 31.2% identity (69.5% similar) in 282 aa overlap (84-354:34-307) 60 70 80 90 100 110 pF1KB9 RGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCI :. :. :.: :.. : .... : :.. CCDS58 GKYRSVSGRAANNVNCGLHLVIQTSSLPEKNKVRFKKVE-FKLNKDTSSFPGR--LLQ-- 10 20 30 40 50 120 130 140 150 160 pF1KB9 ENLEELQSLRELD---LYDNQIKKIENLEALTELEIL-DISFNLLRN-------IEGVDK ..::. : :. : : ....... :. .: .:: . ..: :. :.: :. CCDS58 HDLERNYSSRQGDHINLVSSSLSSFPILQRSSEEKILYSDRLSLERQKLTVCPIINGEDH 60 70 80 90 100 110 170 180 190 200 210 220 pF1KB9 LTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITK : :: : . .: :..:.:.:::..: :.: .:.:. : ...:: :. :.::::.: : CCDS58 L-RL--LNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKK 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB9 LQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIA ..::. : .: ::....:..::::....: .:: : :..: . ...:.. ..:: :.. CCDS58 ISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLR 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB9 SNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRK :.: ......: ::..... : . :..... : . :: . .. ::. .. :.. CCDS58 HNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHT 240 250 260 270 280 290 350 360 pF1KB9 VMLALPSVRQIDATFVRF :. . ..::.: CCDS58 VLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWD 300 310 320 330 340 350 >>CCDS55971.1 LRRC49 gene_id:54839|Hs108|chr15 (642 aa) initn: 605 init1: 334 opt: 372 Z-score: 310.1 bits: 66.8 E(32554): 6e-11 Smith-Waterman score: 372; 34.3% identity (74.2% similar) in 198 aa overlap (157-354:64-258) 130 140 150 160 170 180 pF1KB9 LYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLH :.: :.: :: : . .: :..:.:.:::. CCDS55 FPILQRSSEEKILYSDRLSLERQKLTVCPIINGEDHL-RL--LNFQHNFITRIQNISNLQ 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB9 QLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIE .: :.: .:.:. : ...:: :. :.::::.: :..::. : .: ::....:..:::: CCDS55 KLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIE 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB9 GLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDN ....: .:: : :..: . ...:.. ..:: :.. :.: ......: ::..... : CCDS55 NINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB9 LLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF . :..... : . :: . .. ::. .. :.. :. . ..::.: CCDS55 NISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMA 220 230 240 250 260 270 CCDS55 SVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQQRVANIATNEDRKDSDSPQDP 280 290 300 310 320 330 >>CCDS61694.1 LRRC49 gene_id:54839|Hs108|chr15 (676 aa) initn: 605 init1: 334 opt: 372 Z-score: 309.8 bits: 66.8 E(32554): 6.2e-11 Smith-Waterman score: 372; 34.3% identity (74.2% similar) in 198 aa overlap (157-354:98-292) 130 140 150 160 170 180 pF1KB9 LYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLH :.: :.: :: : . .: :..:.:.:::. CCDS61 FPILQRSSEEKILYSDRLSLERQKLTVCPIINGEDHL-RL--LNFQHNFITRIQNISNLQ 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB9 QLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIE .: :.: .:.:. : ...:: :. :.::::.: :..::. : .: ::....:..:::: CCDS61 KLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIE 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB9 GLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDN ....: .:: : :..: . ...:.. ..:: :.. :.: ......: ::..... : CCDS61 NINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB9 LLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF . :..... : . :: . .. ::. .. :.. :. . ..::.: CCDS61 NISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMA 250 260 270 280 290 300 CCDS61 SVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQQRVANIATNEDRKDSDSPQDP 310 320 330 340 350 360 >>CCDS32282.1 LRRC49 gene_id:54839|Hs108|chr15 (686 aa) initn: 605 init1: 334 opt: 372 Z-score: 309.7 bits: 66.8 E(32554): 6.3e-11 Smith-Waterman score: 372; 34.3% identity (74.2% similar) in 198 aa overlap (157-354:108-302) 130 140 150 160 170 180 pF1KB9 LYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLH :.: :.: :: : . .: :..:.:.:::. CCDS32 FPILQRSSEEKILYSDRLSLERQKLTVCPIINGEDHL-RL--LNFQHNFITRIQNISNLQ 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB9 QLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIE .: :.: .:.:. : ...:: :. :.::::.: :..::. : .: ::....:..:::: CCDS32 KLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB9 GLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDN ....: .:: : :..: . ...:.. ..:: :.. :.: ......: ::..... : CCDS32 NINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB9 LLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF . :..... : . :: . .. ::. .. :.. :. . ..::.: CCDS32 NISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMA 260 270 280 290 300 310 CCDS32 SVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQQRVANIATNEDRKDSDSPQDP 320 330 340 350 360 370 360 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:06:48 2016 done: Fri Nov 4 00:06:49 2016 Total Scan time: 2.800 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]