FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9512, 503 aa 1>>>pF1KB9512 503 - 503 aa - 503 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6920+/-0.000418; mu= 12.6776+/- 0.026 mean_var=153.3689+/-31.043, 0's: 0 Z-trim(115.7): 193 B-trim: 33 in 1/58 Lambda= 0.103563 statistics sampled from 26072 (26308) to 26072 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.308), width: 16 Scan time: 8.840 The best scores are: opt bits E(85289) NP_542970 (OMIM: 602461) tyrosine-protein phosphat ( 504) 3247 497.5 3.7e-140 NP_001035112 (OMIM: 602461) tyrosine-protein phosp ( 504) 3247 497.5 3.7e-140 NP_001035111 (OMIM: 602461) tyrosine-protein phosp ( 504) 3247 497.5 3.7e-140 NP_001317657 (OMIM: 602461) tyrosine-protein phosp ( 508) 3229 494.8 2.4e-139 XP_005260727 (OMIM: 602461) PREDICTED: tyrosine-pr ( 508) 3229 494.8 2.4e-139 XP_011527475 (OMIM: 602461) PREDICTED: tyrosine-pr ( 508) 3039 466.4 8.5e-131 XP_011527436 (OMIM: 603889) PREDICTED: signal-regu ( 381) 2156 334.4 3.6e-91 NP_001129316 (OMIM: 603889) signal-regulatory prot ( 398) 2156 334.4 3.7e-91 NP_001316086 (OMIM: 603889) signal-regulatory prot ( 398) 2156 334.4 3.7e-91 XP_005260698 (OMIM: 603889) PREDICTED: signal-regu ( 397) 1974 307.2 5.7e-83 XP_016883066 (OMIM: 603889) PREDICTED: signal-regu ( 398) 1967 306.2 1.2e-82 NP_006056 (OMIM: 603889) signal-regulatory protein ( 398) 1967 306.2 1.2e-82 XP_016883073 (OMIM: 603889) PREDICTED: signal-regu ( 363) 1954 304.2 4.3e-82 XP_016883072 (OMIM: 603889) PREDICTED: signal-regu ( 363) 1954 304.2 4.3e-82 XP_016883068 (OMIM: 603889) PREDICTED: signal-regu ( 384) 1954 304.2 4.4e-82 XP_016883069 (OMIM: 603889) PREDICTED: signal-regu ( 384) 1954 304.2 4.4e-82 XP_016883067 (OMIM: 603889) PREDICTED: signal-regu ( 384) 1954 304.2 4.4e-82 NP_061026 (OMIM: 605466) signal-regulatory protein ( 387) 1784 278.8 2e-74 XP_011527588 (OMIM: 605466) PREDICTED: signal-regu ( 354) 1721 269.3 1.3e-71 XP_016883071 (OMIM: 603889) PREDICTED: signal-regu ( 364) 1496 235.7 1.7e-61 XP_016883070 (OMIM: 603889) PREDICTED: signal-regu ( 371) 1496 235.7 1.7e-61 XP_005260700 (OMIM: 603889) PREDICTED: signal-regu ( 286) 1356 214.7 2.8e-55 XP_016883074 (OMIM: 603889) PREDICTED: signal-regu ( 287) 1349 213.7 5.9e-55 XP_011527589 (OMIM: 605466) PREDICTED: signal-regu ( 262) 1243 197.8 3.2e-50 NP_001034597 (OMIM: 605466) signal-regulatory prot ( 276) 1243 197.8 3.3e-50 XP_006723608 (OMIM: 602461) PREDICTED: tyrosine-pr ( 291) 881 143.8 6.6e-34 XP_005260806 (OMIM: 605466) PREDICTED: signal-regu ( 281) 709 118.0 3.5e-26 NP_001317568 (OMIM: 603889) signal-regulatory prot ( 180) 705 117.2 3.9e-26 NP_001077379 (OMIM: 603889) signal-regulatory prot ( 181) 698 116.2 8.1e-26 NP_543006 (OMIM: 605466) signal-regulatory protein ( 170) 624 105.1 1.7e-22 NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398) 325 60.8 8.4e-09 NP_067012 (OMIM: 609743) cell adhesion molecule 3 ( 432) 306 58.0 6.4e-08 XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395) 221 45.3 0.0004 XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397) 221 45.3 0.0004 NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404) 221 45.3 0.0004 NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435) 221 45.3 0.00042 XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435) 221 45.3 0.00042 NP_694854 (OMIM: 609938) cell adhesion molecule 2 ( 437) 221 45.3 0.00043 XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449) 221 45.3 0.00043 NP_001333439 (OMIM: 609743) cell adhesion molecule ( 352) 214 44.2 0.00076 NP_004637 (OMIM: 256300,602716) nephrin precursor (1241) 215 44.9 0.0016 NP_872413 (OMIM: 300620) V-set and immunoglobulin ( 387) 190 40.6 0.0097 >>NP_542970 (OMIM: 602461) tyrosine-protein phosphatase (504 aa) initn: 2453 init1: 2453 opt: 3247 Z-score: 2637.2 bits: 497.5 E(85289): 3.7e-140 Smith-Waterman score: 3247; 97.4% identity (99.0% similar) in 504 aa overlap (1-503:1-504) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::::::::::::::::::::::::::::: :::::.: :.::.::: NP_542 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: NP_542 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_542 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR 430 440 450 460 470 480 480 490 500 pF1KB9 TPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::: NP_542 TPKQPAPKPEPSFSEYASVQVPRK 490 500 >>NP_001035112 (OMIM: 602461) tyrosine-protein phosphata (504 aa) initn: 2453 init1: 2453 opt: 3247 Z-score: 2637.2 bits: 497.5 E(85289): 3.7e-140 Smith-Waterman score: 3247; 97.4% identity (99.0% similar) in 504 aa overlap (1-503:1-504) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::::::::::::::::::::::::::::: :::::.: :.::.::: NP_001 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: NP_001 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR 430 440 450 460 470 480 480 490 500 pF1KB9 TPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::: NP_001 TPKQPAPKPEPSFSEYASVQVPRK 490 500 >>NP_001035111 (OMIM: 602461) tyrosine-protein phosphata (504 aa) initn: 2453 init1: 2453 opt: 3247 Z-score: 2637.2 bits: 497.5 E(85289): 3.7e-140 Smith-Waterman score: 3247; 97.4% identity (99.0% similar) in 504 aa overlap (1-503:1-504) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::::::::::::::::::::::::::::: :::::.: :.::.::: NP_001 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: NP_001 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR 430 440 450 460 470 480 480 490 500 pF1KB9 TPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::: NP_001 TPKQPAPKPEPSFSEYASVQVPRK 490 500 >>NP_001317657 (OMIM: 602461) tyrosine-protein phosphata (508 aa) initn: 2439 init1: 1900 opt: 3229 Z-score: 2622.6 bits: 494.8 E(85289): 2.4e-139 Smith-Waterman score: 3229; 96.7% identity (98.2% similar) in 508 aa overlap (1-503:1-508) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::::::::::::::::::::::::::::: :::::.: :.::.::: NP_001 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: NP_001 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQ----DTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV :: :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV 430 440 450 460 470 480 480 490 500 pF1KB9 HLNRTPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::::::: NP_001 HLNRTPKQPAPKPEPSFSEYASVQVPRK 490 500 >>XP_005260727 (OMIM: 602461) PREDICTED: tyrosine-protei (508 aa) initn: 2439 init1: 1900 opt: 3229 Z-score: 2622.6 bits: 494.8 E(85289): 2.4e-139 Smith-Waterman score: 3229; 96.7% identity (98.2% similar) in 508 aa overlap (1-503:1-508) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::::::::::::::::::::::::::::: :::::.: :.::.::: XP_005 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: XP_005 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQ----DTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV :: :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV 430 440 450 460 470 480 480 490 500 pF1KB9 HLNRTPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::::::: XP_005 HLNRTPKQPAPKPEPSFSEYASVQVPRK 490 500 >>XP_011527475 (OMIM: 602461) PREDICTED: tyrosine-protei (508 aa) initn: 2439 init1: 1900 opt: 3039 Z-score: 2469.2 bits: 466.4 E(85289): 8.5e-131 Smith-Waterman score: 3039; 96.5% identity (98.1% similar) in 482 aa overlap (27-503:27-508) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL ::::::::::::::::: :::::.: :.::.::: XP_011 MTLKTRCCIWTLSPALAYFILPEIHRGVAGEEELQVIQPDKSVLVAAGETATLRCTATSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::::::::::.:::::::::::::::::::. :::.:::::: :.::::::::::: XP_011 IPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYY 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TQ----DTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV :: :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMV 430 440 450 460 470 480 480 490 500 pF1KB9 HLNRTPKQPAPKPEPSFSEYASVQVPRK :::::::::::::::::::::::::::: XP_011 HLNRTPKQPAPKPEPSFSEYASVQVPRK 490 500 >>XP_011527436 (OMIM: 603889) PREDICTED: signal-regulato (381 aa) initn: 2242 init1: 1508 opt: 2156 Z-score: 1757.7 bits: 334.4 E(85289): 3.6e-91 Smith-Waterman score: 2156; 91.4% identity (95.0% similar) in 361 aa overlap (3-362:8-362) 10 20 30 40 50 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHC : :.: :. :::. .::::::::::::::::.:::::::: ::: XP_011 MPVPASWPHLPSPFL---LMTLLLGR---LTGVAGEEELQVIQPDKSISVAAGESATLHC 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 TVTSLIPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPAD :::::::::::::::::::.:::::::::::::::::::. :::.:::::: :::::::: XP_011 TVTSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPAD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 AGTYYCVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF ::::::::::::::: .::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTYYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 SPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTL :::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::: XP_011 SPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 TETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 QGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEK :::::: . XP_011 QGSNTAPDLLCASFCSSMISFPASTIQ 360 370 380 >>NP_001129316 (OMIM: 603889) signal-regulatory protein (398 aa) initn: 2149 init1: 1507 opt: 2156 Z-score: 1757.5 bits: 334.4 E(85289): 3.7e-91 Smith-Waterman score: 2156; 84.6% identity (91.4% similar) in 397 aa overlap (3-398:8-397) 10 20 30 40 50 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHC : :.: : . :::. .::::::::::::::::.:::::::: ::: NP_001 MPVPASWPHLPSPFLL---MTLLLG---RLTGVAGEEELQVIQPDKSISVAAGESATLHC 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 TVTSLIPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPAD :::::::::::::::::::.:::::::::::::::::::. :::.:::::: :::::::: NP_001 TVTSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPAD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 AGTYYCVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF ::::::::::::::: .::::::::::::::::::::::::::::::::::::::::::: NP_001 AGTYYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 SPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTL :::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::: NP_001 SPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 TETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 QGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEK :::::: . .. . :. . .:... ....: : .:: NP_001 QGSNTAPGPALASAAPLLIAFLLGPKVLLVVGVSVIY-VYWKQKA 360 370 380 390 420 430 440 450 460 470 pF1KB9 NAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDM >>NP_001316086 (OMIM: 603889) signal-regulatory protein (398 aa) initn: 2149 init1: 1507 opt: 2156 Z-score: 1757.5 bits: 334.4 E(85289): 3.7e-91 Smith-Waterman score: 2156; 84.6% identity (91.4% similar) in 397 aa overlap (3-398:8-397) 10 20 30 40 50 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHC : :.: : . :::. .::::::::::::::::.:::::::: ::: NP_001 MPVPASWPHLPSPFLL---MTLLLG---RLTGVAGEEELQVIQPDKSISVAAGESATLHC 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 TVTSLIPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPAD :::::::::::::::::::.:::::::::::::::::::. :::.:::::: :::::::: NP_001 TVTSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPAD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 AGTYYCVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF ::::::::::::::: .::::::::::::::::::::::::::::::::::::::::::: NP_001 AGTYYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 SPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTL :::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::: NP_001 SPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 TETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 QGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEK :::::: . .. . :. . .:... ....: : .:: NP_001 QGSNTAPGPALASAAPLLIAFLLGPKVLLVVGVSVIY-VYWKQKA 360 370 380 390 420 430 440 450 460 470 pF1KB9 NAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDM >>XP_005260698 (OMIM: 603889) PREDICTED: signal-regulato (397 aa) initn: 1357 init1: 1357 opt: 1974 Z-score: 1610.6 bits: 307.2 E(85289): 5.7e-83 Smith-Waterman score: 1974; 77.8% identity (89.9% similar) in 388 aa overlap (6-392:4-391) 10 20 30 40 50 60 pF1KB9 MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVSVAAGESAILHCTVTSL :: : :::. . .:::::.:::::::.::::::::::: :.:..::: XP_005 MPVPASWPHPPCPFLLLTLLLGLTGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSL 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYY ::::::.:::::: .:::::::::::::::::::: :::.:.:::::::::::::::::: XP_005 IPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYY 60 70 80 90 100 110 130 140 150 160 170 pF1KB9 CVKFRKGSPD-TEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDI :::::::::: .:::::::::::::::::::::::::.::::.::::::::::::::::: XP_005 CVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 TLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPL ::::::::::::::::::::.:.::::::::::.::::: :::::::::.::.::::::: XP_005 TLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 RGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETAS ::::::::.:::::::::::::.:::::.:::::: .:::. :::::::::::::::::: XP_005 RGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETAS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 TVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNT :. ::::::::::::::::. :::::: :::::::::: :::::. :..::: ::.::. XP_005 TLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDI 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 AAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREI . : . . . ... . ::... ..:.:. XP_005 THEAALAPTAPLLVALLLGPKLLLVVGVSAIYICWKQKA 360 370 380 390 420 430 440 450 460 470 pF1KB9 TQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNR 503 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:08:01 2016 done: Fri Nov 4 00:08:03 2016 Total Scan time: 8.840 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]