FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9519, 373 aa
1>>>pF1KB9519 373 - 373 aa - 373 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6318+/-0.000407; mu= 20.5112+/- 0.025
mean_var=110.2677+/-29.438, 0's: 0 Z-trim(112.6): 448 B-trim: 1256 in 1/48
Lambda= 0.122138
statistics sampled from 20969 (21623) to 20969 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.254), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
NP_061842 (OMIM: 300253) probable G-protein couple ( 373) 2570 464.3 2e-130
XP_011529100 (OMIM: 300253) PREDICTED: probable G- ( 373) 2570 464.3 2e-130
XP_016867841 (OMIM: 605188) PREDICTED: probable G- ( 370) 1687 308.7 1.4e-83
NP_001139739 (OMIM: 605188) probable G-protein cou ( 370) 1687 308.7 1.4e-83
XP_005250508 (OMIM: 605188) PREDICTED: probable G- ( 370) 1687 308.7 1.4e-83
NP_061843 (OMIM: 605188) probable G-protein couple ( 370) 1687 308.7 1.4e-83
NP_001139737 (OMIM: 605188) probable G-protein cou ( 370) 1687 308.7 1.4e-83
NP_001139738 (OMIM: 605188) probable G-protein cou ( 370) 1687 308.7 1.4e-83
NP_061844 (OMIM: 605187) probable G-protein couple ( 375) 1379 254.4 3e-67
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 319 67.8 5.7e-11
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 319 67.8 5.9e-11
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 316 67.1 7.3e-11
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 308 65.8 2.1e-10
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 304 65.0 3.1e-10
XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 304 65.0 3.1e-10
NP_001309139 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 304 65.0 3.1e-10
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 304 65.0 3.1e-10
NP_000857 (OMIM: 182134) 5-hydroxytryptamine recep ( 366) 304 65.0 3.1e-10
NP_001309137 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 304 65.0 3.1e-10
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458) 303 65.0 4e-10
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 303 65.0 4e-10
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 302 64.7 4.1e-10
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 302 64.7 4.2e-10
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 298 64.1 7.6e-10
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 276 60.2 1.1e-08
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 272 59.5 1.8e-08
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 265 58.1 3.7e-08
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 265 58.1 3.7e-08
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 253 56.1 1.7e-07
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 251 55.7 2e-07
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 251 55.7 2e-07
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 251 55.8 2.2e-07
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 251 55.8 2.3e-07
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 251 55.8 2.4e-07
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 248 55.2 3.1e-07
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 248 55.2 3.1e-07
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 248 55.2 3.1e-07
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 248 55.2 3.1e-07
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471) 248 55.3 3.4e-07
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 243 54.1 4.9e-07
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 243 54.2 5e-07
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 243 54.2 5e-07
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 243 54.2 5.2e-07
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 244 54.5 5.2e-07
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 244 54.5 5.2e-07
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 244 54.6 5.4e-07
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 243 54.3 5.4e-07
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 243 54.3 5.5e-07
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 244 54.6 5.5e-07
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 244 54.6 5.5e-07
>>NP_061842 (OMIM: 300253) probable G-protein coupled re (373 aa)
initn: 2570 init1: 2570 opt: 2570 Z-score: 2462.5 bits: 464.3 E(85289): 2e-130
Smith-Waterman score: 2570; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGT
310 320 330 340 350 360
370
pF1KB9 GGAPAPREPYCVM
:::::::::::::
NP_061 GGAPAPREPYCVM
370
>>XP_011529100 (OMIM: 300253) PREDICTED: probable G-prot (373 aa)
initn: 2570 init1: 2570 opt: 2570 Z-score: 2462.5 bits: 464.3 E(85289): 2e-130
Smith-Waterman score: 2570; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGT
310 320 330 340 350 360
370
pF1KB9 GGAPAPREPYCVM
:::::::::::::
XP_011 GGAPAPREPYCVM
370
>>XP_016867841 (OMIM: 605188) PREDICTED: probable G-prot (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
XP_016 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
XP_016 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
XP_016 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
XP_016 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
XP_016 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
XP_016 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
XP_016 KSR---LPREPYCVI
360 370
>>NP_001139739 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
NP_001 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
NP_001 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
NP_001 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
NP_001 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
NP_001 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
NP_001 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
NP_001 KSR---LPREPYCVI
360 370
>>XP_005250508 (OMIM: 605188) PREDICTED: probable G-prot (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
XP_005 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
XP_005 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
XP_005 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
XP_005 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
XP_005 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
XP_005 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
XP_005 KSR---LPREPYCVI
360 370
>>NP_061843 (OMIM: 605188) probable G-protein coupled re (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
NP_061 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
NP_061 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
NP_061 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
NP_061 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
NP_061 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
NP_061 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
NP_061 KSR---LPREPYCVI
360 370
>>NP_001139737 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
NP_001 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
NP_001 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
NP_001 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
NP_001 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
NP_001 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
NP_001 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
NP_001 KSR---LPREPYCVI
360 370
>>NP_001139738 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1698 init1: 1293 opt: 1687 Z-score: 1621.6 bits: 308.7 E(85289): 1.4e-83
Smith-Waterman score: 1687; 62.4% identity (86.9% similar) in 375 aa overlap (1-373:1-370)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
::: . ... ::: .:..::. ::.:. ::..:: ..:.:..:...::.:::::
NP_001 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
::::: .: .:::.:::::. ::..::.::...:.::..::..:: :::.::::::::::
NP_001 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
::.::::::::.::.:.::: :::::.::::::::::::.:::::.:::::::: :.::
NP_001 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
:.:::.:::::.::... ::. :: ::..: . .:::::::.: :.:::::::::::.::
NP_001 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 AAANWIAGFGRGPMPPTLLGIRQNGHAASRR-LLGMDEVKGEKQLGRMFYAITLLFLLLW
:::::.::::::: ::::::::::.....:: :: .:: : ::...:::: .:.::: ::
NP_001 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA-PCW
.::.::::::::... .:: .:..:::::::::..::.::.. :..:..:. : :
NP_001 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCR
300 310 320 330 340 350
360 370
pF1KB9 GTGGAPAPREPYCVM
. :::::::.
NP_001 KSR---LPREPYCVI
360 370
>>NP_061844 (OMIM: 605187) probable G-protein coupled re (375 aa)
initn: 970 init1: 398 opt: 1379 Z-score: 1328.3 bits: 254.4 E(85289): 3e-67
Smith-Waterman score: 1379; 54.7% identity (83.4% similar) in 362 aa overlap (1-357:1-355)
10 20 30 40 50 60
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
:::.. :: .:. . .:. .::. :.:..:::::::....::...::.::.::::.
NP_061 MANAS-EP---GGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYL
10 20 30 40 50
70 80 90 100 110
pF1KB9 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFS---ALSCKIVAFMAVLFCFHAAFMLFCI
:::::::::.:. .:.: :. ..:.... . . ::.::..::.:.::::::::.:. .
NP_061 LLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 SVTRYMAIAHHRFYAKRMTLWTCAAV-ICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIF
.::::.:::::::::.:.. : :::. .: ::.:..: :::::.: : :. : .
NP_061 GVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCAL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 EHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPG
:.: : .:::.:.:::...::: :: .::.: . .:::.:...:::.:..:::::::
NP_061 EQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 ATGQAAANWIAGFGRGPMPPTLLGIRQNGHA-ASRRLLGMDEVKGEKQLGRMFYAITLLF
::::::::: ::::::: ::.:.::: : . ..:::: ..: : ::.: .::::.::::
NP_061 ATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 LLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA
::::.::.:: : ::.:. :::. ::...::..::::..::.::::.:..:. :.:..
NP_061 LLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQF
300 310 320 330 340 350
360 370
pF1KB9 PCWGTGGAPAPREPYCVM
::
NP_061 PCCQSPRTTQATHPCDLKGIGL
360 370
>>XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytrypta (456 aa)
initn: 238 init1: 179 opt: 319 Z-score: 317.9 bits: 67.8 E(85289): 5.7e-11
Smith-Waterman score: 326; 23.4% identity (54.3% similar) in 368 aa overlap (8-357:15-372)
10 20 30 40 50
pF1KB9 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERAL
:::.. . . . . .:. ... ...::... : : :. :
XP_006 MLSKITTKPETESIPEEMKQIVEEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 HKAPYYFLLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFM
. : :::..: .:: . . .:..: .. . : . . : :. ::: :..:
XP_006 QYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFST-ASIM
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 LFC-ISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFP-PVFDVGTYKFIREE
.: ::: ::.:: . . . : : ..: .:...:.: :. . : ..
XP_006 HLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKGIETDVDNPNN
120 130 140 150 160 170
180 190 200 210 220
pF1KB9 DQCIFEHRYFKANDTLG----FMLMLAVLMAA----THAVYGKLLLFEYRHRKMKPVQMV
:.. .. : .: :. ::..... ::. : : : :: : .
XP_006 ITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLV-----KNKPPQRL
180 190 200 210 220 230
230 240 250 260 270
pF1KB9 PAISQNWTFH---GPGATGQAAANWIAGFGRGPMPPT--LLGIRQNGHAASRRLLGM-DE
.. . .:. : .. . .: .. .: . .:... ... . . .:
XP_006 TWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDETLMRRTSTIGKKSVQTISNE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB9 VKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKAC--AVPHRYLATAVWMSFAQAAV
.. : :: .:. ::::.: :.... :. .: .. . : ::.......:
XP_006 QRASKVLGIVFF----LFLLMWCPFFITNITLVLCDSCNQTTLQMLLEIFVWIGYVSSGV
300 310 320 330 340 350
340 350 360 370
pF1KB9 NPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM
::.: :.:: .. . . :
XP_006 NPLVYTLFNKTFRDAFGRYITCNYRATKSVKTLRKRSSKIYFRNPMAENSKFFKKHGIRN
360 370 380 390 400 410
373 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:12:13 2016 done: Fri Nov 4 00:12:14 2016
Total Scan time: 7.830 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]