FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9521, 588 aa 1>>>pF1KB9521 588 - 588 aa - 588 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9674+/-0.00078; mu= 13.2984+/- 0.048 mean_var=141.5187+/-30.594, 0's: 0 Z-trim(113.1): 27 B-trim: 1427 in 2/50 Lambda= 0.107812 statistics sampled from 13729 (13753) to 13729 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.422), width: 16 Scan time: 4.150 The best scores are: opt bits E(32554) CCDS8563.1 GPR162 gene_id:27239|Hs108|chr12 ( 588) 4003 634.1 1.5e-181 CCDS44819.1 GPR162 gene_id:27239|Hs108|chr12 ( 304) 2092 336.6 2.7e-92 CCDS64.1 GPR153 gene_id:387509|Hs108|chr1 ( 609) 969 162.2 1.7e-39 >>CCDS8563.1 GPR162 gene_id:27239|Hs108|chr12 (588 aa) initn: 4003 init1: 4003 opt: 4003 Z-score: 3373.1 bits: 634.1 E(32554): 1.5e-181 Smith-Waterman score: 4003; 99.8% identity (99.8% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB9 MARGGAGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MARGGAGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 LMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 WPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 WPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARRVGGGGGTKAGGPGALGTRPAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 VCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARRVGGGGGTKAGGPGALGTRPAFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VPAIVVEDARGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 VPAIVVEDARGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 APPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMSEEDGDDDGGCDDYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 APPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMSEEDGDDDGGCDDYA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EGRVCKVRFDANGATGPGSRDPAQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 EGRVCKVRFDANGATGPGSRDPAQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 STPREPGSFLHKWSSSDDIRVLPAQSRALGGPPEYLGQGHRLEDEEDEEEAEGGGLASLR :::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: CCDS85 STPREPGSFLHKWSSSDDIRVLPAQSRALGGPPEYLGQRHRLEDEEDEEEAEGGGLASLR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QFLESGVLGSGGGPPRGPGFFREEITTFIDETPLPSPTASPGHSPRRPRPLGLSPRRLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 QFLESGVLGSGGGPPRGPGFFREEITTFIDETPLPSPTASPGHSPRRPRPLGLSPRRLSL 490 500 510 520 530 540 550 560 570 580 pF1KB9 GSPESRAVGLPLGLSAGRRCSLTGGEESARAWGGSWGPGNPIFPQLTL :::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 GSPESRAVGLPLGLSAGRRCSLTGGEESARAWGGSWGPGNPIFPQLTL 550 560 570 580 >>CCDS44819.1 GPR162 gene_id:27239|Hs108|chr12 (304 aa) initn: 2092 init1: 2092 opt: 2092 Z-score: 1770.6 bits: 336.6 E(32554): 2.7e-92 Smith-Waterman score: 2092; 99.7% identity (99.7% similar) in 299 aa overlap (290-588:6-304) 260 270 280 290 300 310 pF1KB9 SESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDSAPPWMVLAVLWCSMAQTLL :::::::::::::::::::::::::::::: CCDS44 MLSTGVVSFFSLKSDSAPPWMVLAVLWCSMAQTLL 10 20 30 320 330 340 350 360 370 pF1KB9 LPSFIWSCERYRADVRTVWEQCVAIMSEEDGDDDGGCDDYAEGRVCKVRFDANGATGPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPSFIWSCERYRADVRTVWEQCVAIMSEEDGDDDGGCDDYAEGRVCKVRFDANGATGPGS 40 50 60 70 80 90 380 390 400 410 420 430 pF1KB9 RDPAQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIFSTPREPGSFLHKWSSSDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RDPAQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIFSTPREPGSFLHKWSSSDDI 100 110 120 130 140 150 440 450 460 470 480 490 pF1KB9 RVLPAQSRALGGPPEYLGQGHRLEDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPG ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS44 RVLPAQSRALGGPPEYLGQRHRLEDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPG 160 170 180 190 200 210 500 510 520 530 540 550 pF1KB9 FFREEITTFIDETPLPSPTASPGHSPRRPRPLGLSPRRLSLGSPESRAVGLPLGLSAGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FFREEITTFIDETPLPSPTASPGHSPRRPRPLGLSPRRLSLGSPESRAVGLPLGLSAGRR 220 230 240 250 260 270 560 570 580 pF1KB9 CSLTGGEESARAWGGSWGPGNPIFPQLTL ::::::::::::::::::::::::::::: CCDS44 CSLTGGEESARAWGGSWGPGNPIFPQLTL 280 290 300 >>CCDS64.1 GPR153 gene_id:387509|Hs108|chr1 (609 aa) initn: 945 init1: 692 opt: 969 Z-score: 822.5 bits: 162.2 E(32554): 1.7e-39 Smith-Waterman score: 1611; 47.0% identity (71.2% similar) in 593 aa overlap (8-579:2-564) 10 20 30 40 50 60 pF1KB9 MARGGAGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHI ..: : ..:..::.:: :.:::::: :::..:::.: ::::.::: ::.::. CCDS64 MSDERRLPGSAVGWLVCGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHM 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 LMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVR : .:::..:..::::::: :..:::..:::::::.:::.:::::.:.:::::::::: CCDS64 LNVAVPIATYSVVQLRRQ-RPDFEWNEGLCKVFVSTFYTLTLATCFSVTSLSYHRMWMVC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 WPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFG ::::::::::::::.:.::::::::::::.::..:::...::.:..::.:::..:::::: CCDS64 WPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 VCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARRVGGGGGTKAGGPGALGTRPAFE ::: ::. :...::..:.::...::: .. .::: : :: CCDS64 VCFLLLVGGSVAMGVICTAIALFQTLAVQ--VGRQA------------------DRRAFT 180 190 200 210 250 260 270 280 290 300 pF1KB9 VPAIVVEDARGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDS ::.::::::.::::::.:::: ::::::.:.::..:::.:: : : :.::::: ::..:. CCDS64 VPTIVVEDAQGKRRSSIDGSEPAKTSLQTTGLVTTIVFIYDCLMGFPVLVVSFSSLRADA 220 230 240 250 260 270 310 320 330 340 350 pF1KB9 APPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMS-EEDGDDD----GG . :::.: :::::.::.:::: :.:.:.:::::...: :.:.:.:. .:..::. :: CCDS64 SAPWMALCVLWCSVAQALLLPVFLWACDRYRADLKAVREKCMALMANDEESDDETSLEGG 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB9 CD-DYAEGRVCKVRFDANGATGPGSRDPAQVKLLPGRHMLFP--PLE--RVHYLQVPLSR . : . : . .. .. : : .:.: ::. ...::::: .: CCDS64 ISPDLVLERSLDYGYGGDFVALDRMAKYEISALEGGLPQLYPLRPLQEDKMQYLQVPPTR 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 RLSHDETNIFSTPREPGSFLHKWSSSDDIRVLPAQSRALGGPPEYLGQGHRLEDEEDEEE :.:::....... : .:: .:.:..:. .: :. .:: . .. . .. . CCDS64 RFSHDDADVWAAVPLP-AFLPRWGSGEDLAAL-AHLVLPAGPERRRASLLAFAEDAPPSR 400 410 420 430 440 450 480 490 500 510 520 pF1KB9 AE---GGGLASLR-QFLESGVLG---SGGGPPR---GPGFFREEITTFIDETPLPSPTAS :. . .: ::: . :.:: : : : :: ::: . . : : . CCDS64 ARRRSAESLLSLRPSALDSGPRGARDSPPGSPRRRPGPGPRSASASLLPDAFALTAFECE 460 470 480 490 500 510 530 540 550 560 570 pF1KB9 PGHSPRRPRPLGLSPRRLSLGSPESRAVG-LPLGLSAGRRCSLTGGEESARAWGGSWGPG : : : :. .: ..:.. : : :...: : . ::.. .:: :: CCDS64 PQALRRPPGPFPAAP-----AAPDGADPGEAPTPPSSAQRSP--GPRPSAHSHAGSLRPG 520 530 540 550 560 580 pF1KB9 NPIFPQLTL CCDS64 LSASWGEPGGLRAAGGGGSTSSFLSSPSESSGYATLHSDSLGSAS 570 580 590 600 588 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:06:49 2016 done: Fri Nov 4 17:06:50 2016 Total Scan time: 4.150 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]