FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9537, 395 aa 1>>>pF1KB9537 395 - 395 aa - 395 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5190+/-0.000752; mu= 15.5192+/- 0.045 mean_var=64.7127+/-13.111, 0's: 0 Z-trim(108.9): 20 B-trim: 63 in 1/48 Lambda= 0.159433 statistics sampled from 10500 (10516) to 10500 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.323), width: 16 Scan time: 2.920 The best scores are: opt bits E(32554) CCDS1561.1 JMJD4 gene_id:65094|Hs108|chr1 ( 463) 2796 651.7 3.9e-187 CCDS59203.1 JMJD4 gene_id:65094|Hs108|chr1 ( 447) 2060 482.4 3.5e-136 CCDS42384.1 JMJD6 gene_id:23210|Hs108|chr17 ( 403) 296 76.6 4.4e-14 CCDS42383.1 JMJD6 gene_id:23210|Hs108|chr17 ( 414) 296 76.6 4.5e-14 >>CCDS1561.1 JMJD4 gene_id:65094|Hs108|chr1 (463 aa) initn: 2796 init1: 2796 opt: 2796 Z-score: 3473.1 bits: 651.7 E(32554): 3.9e-187 Smith-Waterman score: 2796; 100.0% identity (100.0% similar) in 391 aa overlap (5-395:73-463) 10 20 30 pF1KB9 MRAGPGRVAFVSEPGAFSYADFVRGFLLPNLPCV :::::::::::::::::::::::::::::: CCDS15 VLSWMDRETRALADSHFRGLGVDVPGVGQAPGRVAFVSEPGAFSYADFVRGFLLPNLPCV 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB9 FSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 FSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYI 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB9 TYWKEYIQAGYSSPRGCLYLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 TYWKEYIQAGYSSPRGCLYLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRF 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB9 VYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 VYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALC 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB9 DTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 DTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRF 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB9 LQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLREAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 LQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLREAA 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB9 AEDGAGLGFEQAAFDVGRITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 AEDGAGLGFEQAAFDVGRITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAA 410 420 430 440 450 460 pF1KB9 P : CCDS15 P >>CCDS59203.1 JMJD4 gene_id:65094|Hs108|chr1 (447 aa) initn: 2060 init1: 2060 opt: 2060 Z-score: 2558.4 bits: 482.4 E(32554): 3.5e-136 Smith-Waterman score: 2613; 95.9% identity (95.9% similar) in 391 aa overlap (5-395:73-447) 10 20 30 pF1KB9 MRAGPGRVAFVSEPGAFSYADFVRGFLLPNLPCV :::::::::::::::::::::::::::::: CCDS59 VLSWMDRETRALADSHFRGLGVDVPGVGQAPGRVAFVSEPGAFSYADFVRGFLLPNLPCV 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB9 FSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYI 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB9 TYWKEYIQAGYSSPRGCLYLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TYWKEYIQAGYSSPRGCLYLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRF 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB9 VYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALC 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB9 DTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRF 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB9 LQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLREAA :::::::::::: :::::::::::::::::::::::::::::::: CCDS59 LQQELCAVQEEV----------------IMRSCSGINFEEFYHFLKVIAEKRLLVLREAA 350 360 370 380 340 350 360 370 380 390 pF1KB9 AEDGAGLGFEQAAFDVGRITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 AEDGAGLGFEQAAFDVGRITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAA 390 400 410 420 430 440 pF1KB9 P : CCDS59 P >>CCDS42384.1 JMJD6 gene_id:23210|Hs108|chr17 (403 aa) initn: 288 init1: 165 opt: 296 Z-score: 366.3 bits: 76.6 E(32554): 4.4e-14 Smith-Waterman score: 336; 31.1% identity (56.3% similar) in 270 aa overlap (17-272:54-298) 10 20 30 40 pF1KB9 MRAGPGRVAFVSEPGAFSYADFVRGFLLPNLPCVFSSAFTQGWGSR .: .::. . : : :. .: .::... CCDS42 LDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFVERYERPYKPVVLLNA-QEGWSAQ 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB9 RRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYITYWKEYIQAGYS ..:. ...: : : . .:: : :.. . .: .. :: ::... . CCDS42 EKWT-------LERLKRKYRN---QKFKCG--EDNDGYSVKMKMKYYI----EYMESTRD 90 100 110 120 110 120 130 140 150 160 pF1KB9 -SPRGCLYLKD----WHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRFVYAGPAG :: ::. : : : .:: . .: .:..: : .. ::. :: CCDS42 DSP---LYIFDSSYGEHPKRRKLLED-YKVPKFFTDD-LFQYAGEKRRPPYRWFVMGPPR 130 140 150 160 170 180 170 180 190 200 210 pF1KB9 SWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEAL----RDRHGNLPYDVTSPALCDTH : . .: : . . .:.. : :.:.: ::: . . : ::. :: .. . . CCDS42 SGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWF---NV 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 LHPRNQLAG-PP----LEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMW ..::.:: :: ::: :. :: ::::.:: : : ::: ::.:..:.... :. .: CCDS42 IYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVW 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 RFLQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLRE CCDS42 HKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQESTGIASDSSSDSSSSSSSSSSDSD 300 310 320 330 340 350 >>CCDS42383.1 JMJD6 gene_id:23210|Hs108|chr17 (414 aa) initn: 288 init1: 165 opt: 296 Z-score: 366.1 bits: 76.6 E(32554): 4.5e-14 Smith-Waterman score: 336; 31.1% identity (56.3% similar) in 270 aa overlap (17-272:54-298) 10 20 30 40 pF1KB9 MRAGPGRVAFVSEPGAFSYADFVRGFLLPNLPCVFSSAFTQGWGSR .: .::. . : : :. .: .::... CCDS42 LDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFVERYERPYKPVVLLNA-QEGWSAQ 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB9 RRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYITYWKEYIQAGYS ..:. ...: : : . .:: : :.. . .: .. :: ::... . CCDS42 EKWT-------LERLKRKYRN---QKFKCG--EDNDGYSVKMKMKYYI----EYMESTRD 90 100 110 120 110 120 130 140 150 160 pF1KB9 -SPRGCLYLKD----WHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRFVYAGPAG :: ::. : : : .:: . .: .:..: : .. ::. :: CCDS42 DSP---LYIFDSSYGEHPKRRKLLED-YKVPKFFTDD-LFQYAGEKRRPPYRWFVMGPPR 130 140 150 160 170 180 170 180 190 200 210 pF1KB9 SWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEAL----RDRHGNLPYDVTSPALCDTH : . .: : . . .:.. : :.:.: ::: . . : ::. :: .. . . CCDS42 SGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWF---NV 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 LHPRNQLAG-PP----LEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMW ..::.:: :: ::: :. :: ::::.:: : : ::: ::.:..:.... :. .: CCDS42 IYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVW 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 RFLQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLRE CCDS42 HKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQESTGIASDSSSDSSSSSSSSSSDSD 300 310 320 330 340 350 395 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:19:42 2016 done: Sat Nov 5 02:19:43 2016 Total Scan time: 2.920 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]