FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9544, 601 aa 1>>>pF1KB9544 601 - 601 aa - 601 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7699+/-0.000344; mu= 4.2886+/- 0.022 mean_var=206.3536+/-42.285, 0's: 0 Z-trim(121.6): 68 B-trim: 1012 in 1/58 Lambda= 0.089283 statistics sampled from 38343 (38427) to 38343 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.451), width: 16 Scan time: 10.250 The best scores are: opt bits E(85289) NP_001003681 (OMIM: 604702) HMG domain-containing ( 601) 3880 512.4 1.7e-144 XP_006724163 (OMIM: 604702) PREDICTED: HMG domain- ( 644) 3825 505.4 2.4e-142 XP_006724164 (OMIM: 604702) PREDICTED: HMG domain- ( 603) 3466 459.1 1.9e-128 XP_006724165 (OMIM: 604702) PREDICTED: HMG domain- ( 492) 3172 421.2 4.1e-117 >>NP_001003681 (OMIM: 604702) HMG domain-containing prot (601 aa) initn: 3880 init1: 3880 opt: 3880 Z-score: 2715.2 bits: 512.4 E(85289): 1.7e-144 Smith-Waterman score: 3880; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:1-601) 10 20 30 40 50 60 pF1KB9 MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG 550 560 570 580 590 600 pF1KB9 L : NP_001 L >>XP_006724163 (OMIM: 604702) PREDICTED: HMG domain-cont (644 aa) initn: 3822 init1: 3822 opt: 3825 Z-score: 2676.5 bits: 505.4 E(85289): 2.4e-142 Smith-Waterman score: 3825; 99.2% identity (99.5% similar) in 598 aa overlap (4-601:47-644) 10 20 30 pF1KB9 MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREK : . .:::::::::::::::::::::::: XP_006 VCALGSTEAPWPLALFSPSPRWRRSAALRRDPGEPSEDCFDGDHTFEDIGLAAGRSQREK 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 KRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYGDISSLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYGDISSLES 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 SQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVS 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB9 GSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQY 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 PSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB9 FAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEK 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB9 HKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKK 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB9 EEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDK 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB9 LIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASP 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB9 AKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSIICALGPLACLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSIICALGPLACLT 560 570 580 590 600 610 580 590 600 pF1KB9 TQLPELNGCPKQVLSNTLDNIAYIMPGL :::::::::::::::::::::::::::: XP_006 TQLPELNGCPKQVLSNTLDNIAYIMPGL 620 630 640 >>XP_006724164 (OMIM: 604702) PREDICTED: HMG domain-cont (603 aa) initn: 3463 init1: 3463 opt: 3466 Z-score: 2427.0 bits: 459.1 E(85289): 1.9e-128 Smith-Waterman score: 3466; 99.1% identity (99.4% similar) in 543 aa overlap (4-546:47-589) 10 20 30 pF1KB9 MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREK : . .:::::::::::::::::::::::: XP_006 VCALGSTEAPWPLALFSPSPRWRRSAALRRDPGEPSEDCFDGDHTFEDIGLAAGRSQREK 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 KRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYGDISSLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYGDISSLES 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 SQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVS 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB9 GSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQY 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 PSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB9 FAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEK 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB9 HKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKK 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB9 EEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDK 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB9 LIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASP 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB9 AKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSIICALGPLACLT ::::::::::::::::::::::::::::::::: XP_006 AKAPETEPIDVAAHLQLLGESLSLIGHRLQETESNTLDNIAYIMPGL 560 570 580 590 600 580 590 600 pF1KB9 TQLPELNGCPKQVLSNTLDNIAYIMPGL >>XP_006724165 (OMIM: 604702) PREDICTED: HMG domain-cont (492 aa) initn: 3172 init1: 3172 opt: 3172 Z-score: 2223.5 bits: 421.2 E(85289): 4.1e-117 Smith-Waterman score: 3172; 100.0% identity (100.0% similar) in 492 aa overlap (110-601:1-492) 80 90 100 110 120 130 pF1KB9 SDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSS :::::::::::::::::::::::::::::: XP_006 MDLLKAITSPLAAGSKPSKKTGEKSSGSSS 10 20 30 140 150 160 170 180 190 pF1KB9 HSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPK 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB9 EKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAH 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB9 SSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB9 KKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB9 GLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB9 KLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQ 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB9 KKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLL 400 410 420 430 440 450 560 570 580 590 600 pF1KB9 DSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPGL :::::::::::::::::::::::::::::::::::::::::: XP_006 DSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPGL 460 470 480 490 601 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:07:57 2016 done: Fri Nov 4 17:07:59 2016 Total Scan time: 10.250 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]