FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9557, 2004 aa 1>>>pF1KB9557 2004 - 2004 aa - 2004 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 20.2670+/-0.000585; mu= -45.6603+/- 0.037 mean_var=907.9129+/-183.424, 0's: 0 Z-trim(124.3): 78 B-trim: 22 in 1/56 Lambda= 0.042565 statistics sampled from 45524 (45605) to 45524 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.535), width: 16 Scan time: 19.080 The best scores are: opt bits E(85289) NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 13592 851.7 0 XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 13592 851.7 0 XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 13592 851.7 0 XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 10220 644.6 3.1e-183 XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 10220 644.6 3.1e-183 XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 10220 644.6 3.1e-183 XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 10220 644.6 3.1e-183 NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 5590 360.1 5.5e-98 XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 2746 185.6 4.5e-45 XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 2035 142.0 5.9e-32 NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 2035 142.0 5.9e-32 XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 1795 127.2 1.5e-27 XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 1774 125.9 3.8e-27 XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 1774 125.9 3.8e-27 NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 1774 125.9 3.8e-27 XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 1774 125.9 3.8e-27 XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 1776 126.1 3.9e-27 NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 1776 126.1 3.9e-27 XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 1776 126.1 3.9e-27 XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 1776 126.1 3.9e-27 XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 1776 126.1 3.9e-27 XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 1776 126.1 3.9e-27 NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1222 91.8 2e-17 XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1209 90.9 2.4e-17 NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1215 91.3 2.4e-17 NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1209 91.0 3.3e-17 NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1210 91.1 3.8e-17 NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1209 91.0 4.2e-17 XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 1049 81.1 2e-14 XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 1049 81.1 2e-14 NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 1049 81.1 2.9e-14 NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 1005 78.4 1.9e-13 NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 1005 78.5 2e-13 NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 1005 78.5 2.1e-13 XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 1005 78.5 2.1e-13 NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 1005 78.5 2.2e-13 NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 995 77.8 3e-13 XP_016873590 (OMIM: 601671) PREDICTED: zinc finger ( 385) 496 47.1 0.00042 NP_001317237 (OMIM: 601671) zinc finger protein ub ( 405) 496 47.2 0.00044 XP_016877159 (OMIM: 601672) PREDICTED: zinc finger ( 378) 491 46.8 0.00051 NP_001267471 (OMIM: 601672) zinc finger protein DP ( 378) 491 46.8 0.00051 XP_016873591 (OMIM: 601671) PREDICTED: zinc finger ( 371) 489 46.7 0.00055 XP_005259349 (OMIM: 601670) PREDICTED: zinc finger ( 369) 488 46.6 0.00057 NP_006259 (OMIM: 601671) zinc finger protein ubi-d ( 391) 489 46.7 0.00058 XP_005259346 (OMIM: 601670) PREDICTED: zinc finger ( 397) 488 46.7 0.00061 NP_001128628 (OMIM: 601670) zinc finger protein ne ( 332) 482 46.3 0.00067 XP_005259347 (OMIM: 601670) PREDICTED: zinc finger ( 388) 482 46.3 0.00077 NP_001128627 (OMIM: 601670) zinc finger protein ne ( 414) 482 46.3 0.00082 NP_579866 (OMIM: 613069) PHD finger protein 10 iso ( 496) 428 43.0 0.0095 NP_060758 (OMIM: 613069) PHD finger protein 10 iso ( 498) 428 43.0 0.0095 >>NP_006757 (OMIM: 601408,616268) histone acetyltransfer (2004 aa) initn: 13592 init1: 13592 opt: 13592 Z-score: 4529.8 bits: 851.7 E(85289): 0 Smith-Waterman score: 13592; 100.0% identity (100.0% similar) in 2004 aa overlap (1-2004:1-2004) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB9 PSHHSYMNAAGVPKQSLNGPYMRR :::::::::::::::::::::::: NP_006 PSHHSYMNAAGVPKQSLNGPYMRR 1990 2000 >>XP_016869352 (OMIM: 601408,616268) PREDICTED: histone (2004 aa) initn: 13592 init1: 13592 opt: 13592 Z-score: 4529.8 bits: 851.7 E(85289): 0 Smith-Waterman score: 13592; 100.0% identity (100.0% similar) in 2004 aa overlap (1-2004:1-2004) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB9 PSHHSYMNAAGVPKQSLNGPYMRR :::::::::::::::::::::::: XP_016 PSHHSYMNAAGVPKQSLNGPYMRR 1990 2000 >>XP_016869353 (OMIM: 601408,616268) PREDICTED: histone (2004 aa) initn: 13592 init1: 13592 opt: 13592 Z-score: 4529.8 bits: 851.7 E(85289): 0 Smith-Waterman score: 13592; 100.0% identity (100.0% similar) in 2004 aa overlap (1-2004:1-2004) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB9 PSHHSYMNAAGVPKQSLNGPYMRR :::::::::::::::::::::::: XP_016 PSHHSYMNAAGVPKQSLNGPYMRR 1990 2000 >>XP_011542961 (OMIM: 601408,616268) PREDICTED: histone (2041 aa) initn: 12572 init1: 10218 opt: 10220 Z-score: 3410.6 bits: 644.6 E(85289): 3.1e-183 Smith-Waterman score: 13401; 97.5% identity (97.5% similar) in 2043 aa overlap (6-2004:6-2041) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP ::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_011 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNR-------SKGPFSKVRTGP 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 420 430 440 450 460 470 490 pF1KB9 DMELFRDIQEQALQ--------------------------------------------KV :::::::::::::: :: XP_011 DMELFRDIQEQALQTCAVVVMCKQLYWNWISTFTSGIRLEEQRAADGKTLKQQTVPQQKV 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB9 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB9 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY 600 610 620 630 640 650 620 630 640 650 660 670 pF1KB9 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA 660 670 680 690 700 710 680 690 700 710 720 730 pF1KB9 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM 720 730 740 750 760 770 740 750 760 770 780 790 pF1KB9 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE 780 790 800 810 820 830 800 810 820 830 840 850 pF1KB9 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL 840 850 860 870 880 890 860 870 880 890 900 910 pF1KB9 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES 900 910 920 930 940 950 920 930 940 950 960 970 pF1KB9 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG 960 970 980 990 1000 1010 980 990 1000 1010 1020 1030 pF1KB9 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE 1020 1030 1040 1050 1060 1070 1040 1050 1060 1070 1080 1090 pF1KB9 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC 1080 1090 1100 1110 1120 1130 1100 1110 1120 1130 1140 1150 pF1KB9 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK 1140 1150 1160 1170 1180 1190 1160 1170 1180 1190 1200 1210 pF1KB9 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED 1200 1210 1220 1230 1240 1250 1220 1230 1240 1250 1260 1270 pF1KB9 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1260 1270 1280 1290 1300 1310 1280 1290 1300 1310 1320 1330 pF1KB9 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1320 1330 1340 1350 1360 1370 1340 1350 1360 1370 1380 1390 pF1KB9 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH 1380 1390 1400 1410 1420 1430 1400 1410 1420 1430 1440 1450 pF1KB9 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1440 1450 1460 1470 1480 1490 1460 1470 1480 1490 1500 1510 pF1KB9 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ 1500 1510 1520 1530 1540 1550 1520 1530 1540 1550 1560 1570 pF1KB9 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS 1560 1570 1580 1590 1600 1610 1580 1590 1600 1610 1620 1630 pF1KB9 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ 1620 1630 1640 1650 1660 1670 1640 1650 1660 1670 1680 1690 pF1KB9 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP 1680 1690 1700 1710 1720 1730 1700 1710 1720 1730 1740 1750 pF1KB9 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL 1740 1750 1760 1770 1780 1790 1760 1770 1780 1790 1800 1810 pF1KB9 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL 1800 1810 1820 1830 1840 1850 1820 1830 1840 1850 1860 1870 pF1KB9 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG 1860 1870 1880 1890 1900 1910 1880 1890 1900 1910 1920 1930 pF1KB9 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY 1920 1930 1940 1950 1960 1970 1940 1950 1960 1970 1980 1990 pF1KB9 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS 1980 1990 2000 2010 2020 2030 2000 pF1KB9 LNGPYMRR :::::::: XP_011 LNGPYMRR 2040 >>XP_011542960 (OMIM: 601408,616268) PREDICTED: histone (2048 aa) initn: 10218 init1: 10218 opt: 10220 Z-score: 3410.5 bits: 644.6 E(85289): 3.1e-183 Smith-Waterman score: 13410; 97.8% identity (97.8% similar) in 2036 aa overlap (13-2004:13-2048) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 pF1KB9 DMELFRDIQEQALQ--------------------------------------------KV :::::::::::::: :: XP_011 DMELFRDIQEQALQTCAVVVMCKQLYWNWISTFTSGIRLEEQRAADGKTLKQQTVPQQKV 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB9 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB9 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB9 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB9 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB9 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE 790 800 810 820 830 840 800 810 820 830 840 850 pF1KB9 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL 850 860 870 880 890 900 860 870 880 890 900 910 pF1KB9 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES 910 920 930 940 950 960 920 930 940 950 960 970 pF1KB9 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KB9 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KB9 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB9 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KB9 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KB9 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1270 1280 1290 1300 1310 1320 1280 1290 1300 1310 1320 1330 pF1KB9 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1330 1340 1350 1360 1370 1380 1340 1350 1360 1370 1380 1390 pF1KB9 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH 1390 1400 1410 1420 1430 1440 1400 1410 1420 1430 1440 1450 pF1KB9 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1450 1460 1470 1480 1490 1500 1460 1470 1480 1490 1500 1510 pF1KB9 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ 1510 1520 1530 1540 1550 1560 1520 1530 1540 1550 1560 1570 pF1KB9 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KB9 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KB9 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KB9 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KB9 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KB9 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KB9 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KB9 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS 1990 2000 2010 2020 2030 2040 2000 pF1KB9 LNGPYMRR :::::::: XP_011 LNGPYMRR >>XP_011542958 (OMIM: 601408,616268) PREDICTED: histone (2048 aa) initn: 10218 init1: 10218 opt: 10220 Z-score: 3410.5 bits: 644.6 E(85289): 3.1e-183 Smith-Waterman score: 13410; 97.8% identity (97.8% similar) in 2036 aa overlap (13-2004:13-2048) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 pF1KB9 DMELFRDIQEQALQ--------------------------------------------KV :::::::::::::: :: XP_011 DMELFRDIQEQALQTCAVVVMCKQLYWNWISTFTSGIRLEEQRAADGKTLKQQTVPQQKV 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB9 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB9 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB9 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB9 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB9 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE 790 800 810 820 830 840 800 810 820 830 840 850 pF1KB9 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL 850 860 870 880 890 900 860 870 880 890 900 910 pF1KB9 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES 910 920 930 940 950 960 920 930 940 950 960 970 pF1KB9 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KB9 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KB9 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB9 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KB9 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KB9 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1270 1280 1290 1300 1310 1320 1280 1290 1300 1310 1320 1330 pF1KB9 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1330 1340 1350 1360 1370 1380 1340 1350 1360 1370 1380 1390 pF1KB9 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH 1390 1400 1410 1420 1430 1440 1400 1410 1420 1430 1440 1450 pF1KB9 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1450 1460 1470 1480 1490 1500 1460 1470 1480 1490 1500 1510 pF1KB9 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ 1510 1520 1530 1540 1550 1560 1520 1530 1540 1550 1560 1570 pF1KB9 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KB9 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KB9 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KB9 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KB9 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KB9 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KB9 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KB9 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS 1990 2000 2010 2020 2030 2040 2000 pF1KB9 LNGPYMRR :::::::: XP_011 LNGPYMRR >>XP_011542959 (OMIM: 601408,616268) PREDICTED: histone (2048 aa) initn: 10218 init1: 10218 opt: 10220 Z-score: 3410.5 bits: 644.6 E(85289): 3.1e-183 Smith-Waterman score: 13410; 97.8% identity (97.8% similar) in 2036 aa overlap (13-2004:13-2048) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 pF1KB9 DMELFRDIQEQALQ--------------------------------------------KV :::::::::::::: :: XP_011 DMELFRDIQEQALQTCAVVVMCKQLYWNWISTFTSGIRLEEQRAADGKTLKQQTVPQQKV 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB9 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQH 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB9 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFY 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB9 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQA 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB9 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRM 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB9 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEE 790 800 810 820 830 840 800 810 820 830 840 850 pF1KB9 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSL 850 860 870 880 890 900 860 870 880 890 900 910 pF1KB9 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTES 910 920 930 940 950 960 920 930 940 950 960 970 pF1KB9 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEG 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KB9 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTE 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KB9 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB9 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KB9 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KB9 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1270 1280 1290 1300 1310 1320 1280 1290 1300 1310 1320 1330 pF1KB9 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1330 1340 1350 1360 1370 1380 1340 1350 1360 1370 1380 1390 pF1KB9 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH 1390 1400 1410 1420 1430 1440 1400 1410 1420 1430 1440 1450 pF1KB9 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1450 1460 1470 1480 1490 1500 1460 1470 1480 1490 1500 1510 pF1KB9 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQ 1510 1520 1530 1540 1550 1560 1520 1530 1540 1550 1560 1570 pF1KB9 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGS 1570 1580 1590 1600 1610 1620 1580 1590 1600 1610 1620 1630 pF1KB9 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQ 1630 1640 1650 1660 1670 1680 1640 1650 1660 1670 1680 1690 pF1KB9 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPP 1690 1700 1710 1720 1730 1740 1700 1710 1720 1730 1740 1750 pF1KB9 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKL 1750 1760 1770 1780 1790 1800 1760 1770 1780 1790 1800 1810 pF1KB9 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNL 1810 1820 1830 1840 1850 1860 1820 1830 1840 1850 1860 1870 pF1KB9 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYG 1870 1880 1890 1900 1910 1920 1880 1890 1900 1910 1920 1930 pF1KB9 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSY 1930 1940 1950 1960 1970 1980 1940 1950 1960 1970 1980 1990 pF1KB9 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQS 1990 2000 2010 2020 2030 2040 2000 pF1KB9 LNGPYMRR :::::::: XP_011 LNGPYMRR >>NP_001292807 (OMIM: 601408,616268) histone acetyltrans (815 aa) initn: 5628 init1: 5590 opt: 5590 Z-score: 1880.1 bits: 360.1 E(85289): 5.5e-98 Smith-Waterman score: 5590; 100.0% identity (100.0% similar) in 813 aa overlap (1-813:1-813) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP ::::::::::::::::::::::::::::::::: NP_001 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVRA 790 800 810 850 860 870 880 890 900 pF1KB9 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG >>XP_016871493 (OMIM: 603736,605880,606170) PREDICTED: h (2019 aa) initn: 4132 init1: 1061 opt: 2746 Z-score: 930.2 bits: 185.6 E(85289): 4.5e-45 Smith-Waterman score: 5852; 47.6% identity (64.4% similar) in 2271 aa overlap (1-2004:1-2019) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::.:.:::::::::::::.:::.:::::.::: :::::::.::.. XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE :::.:::: ::::::::::.. :: ..:. .. .:::::::..::.::: : XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK .::.::.::..:..:.:... .. : :.:.:::. :::...:::::::: ::.: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC . . : . : : ::::::::::::.: :.:::::::::::::.:::::::::.:: XP_016 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM ::::.::::::::: ::::. :::::::::::::::.:: ::.::::::::::::::::: XP_016 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT :::::::.::::::::::.:::.:::::::..:::::::::..:::::::.::.. : XP_016 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 300 310 320 330 340 350 350 360 370 380 390 pF1KB9 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- ..: .. : .::::.: :. . .:. ..: . :. : : XP_016 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 360 370 380 390 400 410 400 410 420 430 440 pF1KB9 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKR---------- : .:: ::::::::::::::::::::::..:::..:.:..:: ::. XP_016 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSH 420 430 440 450 460 470 450 pF1KB9 ----------------------------GNRKSST-------------------SDWPTD ...:::: :. :. XP_016 VLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN 480 490 500 510 520 530 pF1KB9 NQ-----DG--------------------------------------------------- .: :: XP_016 SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRF 540 550 560 570 580 590 460 pF1KB9 --------W------------------------------------------------DG- : :: XP_016 ISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGR 600 610 620 630 640 650 470 480 490 500 pF1KB9 ---------------KQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQV :::. . ..:.....::.:...:.. :: . .:. . . XP_016 IKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG 660 670 680 690 700 710 510 520 530 540 550 560 pF1KB9 RCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPP : :::::::::::.:::::::::::.:::::::::::::::::..:: .: ::::::::: XP_016 RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPP 720 730 740 750 760 770 570 580 590 600 610 620 pF1KB9 ANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGC ::::::....:::: XP_016 ANEIYRRKDLSVFE---------------------------------------------- 780 790 630 640 650 660 670 680 pF1KB9 HLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDL :: ::::::::::::.::.::.:.::::::::::::.::::::::::::::: XP_016 --------EKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDL 800 810 820 830 840 690 700 710 720 730 740 pF1KB9 GRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI :::::.::::::::: :::.....:::: .:. ::.::.::..::.::.:.: :. .::: XP_016 GRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 850 860 870 880 890 900 750 760 770 780 790 800 pF1KB9 IRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGEN--EEPQC ::::::: .:: ::. : ..::. :::::...::..:::::.: .:.: :. .: XP_016 IRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 910 920 930 940 950 960 810 820 830 840 850 860 pF1KB9 QERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSR :.: :: :... ...: : ::. : . XP_016 WEKE--------------EQ-----------EILSTRANSRQS---------PAKVQSKN 970 980 870 880 890 900 910 920 pF1KB9 RGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASE . . ..: . :.. . : : . :: .:. : :. : .:. :.::. : XP_016 KYLHSPESRPVT---GERGQLLELSKESSEEEEE--EEDEEEEEEEEEEEEDEEE----E 990 1000 1010 1020 1030 1040 930 940 950 960 970 980 pF1KB9 EQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGF :. XP_016 EE---------------------------------------------------------- 990 1000 1010 1020 1030 1040 pF1KB9 SESSEEEEEPESPRSSSPPILTKP---TLKRKKPFLHRRRRVRKRKHHNSSVVTETISET ::::: : .:::: :::: ..:::.::. ...: :::.. ::::.::::::: XP_016 ----EEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISET 1050 1060 1070 1080 1090 1050 1060 1070 1080 1090 1100 pF1KB9 TEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSK ::::.:::..:: :::::.:::: :: : ::: . :. :.. : ..: XP_016 TEVLNEPFDNSDEERPMPQLEPTCEI---EVEEDGRKPVLRKAFQH---------QPGKK 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB9 RKSKDEEEDEESDDADDTPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKP :.. :.::. : : . : .: . :. ::: :. :::: .: XP_016 RQT----EEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGL 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KB9 IHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLP .:.. :: ::::. : . .:: .. ..:..:: : : . : : XP_016 SKWRQNKERKTGFKLNLYTPPETP----MEP-------DEQVTVEEQKETSEGKTS-PSP 1210 1220 1230 1240 1250 1230 1240 1250 1260 1270 pF1KB9 ----EERKEEEEMQAEAEEAEEGEEEDAASSEV-PAASPADSSNSPETETKEPEVEEEEE :: :: : :: .. : .: .. :. .: :. .:: : .: : ::::: XP_016 IRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEE 1260 1270 1280 1290 1300 1310 1280 1290 1300 1310 pF1KB9 KPRVSEEQRQS---EEE-----QQELEEPE-------------PEEEEDAAAETAQNDDH . . .::.. . :.. .:: :::: ::::. : ..:.:: XP_016 EEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDH 1320 1330 1340 1350 1360 1370 1320 1330 1340 1350 1360 1370 pF1KB9 DADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD-- :::::::.:.::.. : :: : ::. :: ::.::: :.: .. . . . .: XP_016 DADDEDDSHMESAEV-EKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLT 1380 1390 1400 1410 1420 1380 1390 1400 1410 1420 pF1KB9 ----SEEEQPSHDTSVVSEQ----MAGSEDDHEEDSHTKEELIELKEEEEIPHS-ELDLE :: .. . : .: :. : . ........:: :.:: . : . :.: : XP_016 ASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGN--PATMEIDSE 1430 1440 1450 1460 1470 1480 1430 1440 1450 1460 1470 1480 pF1KB9 TVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQM-SMVEDCHASEHNSP ::::::::::: :::.. ..::: :: ::..::.::.::..::. . ..::. :.:.:: XP_016 TVQAVQSLTQE-SSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSP 1490 1500 1510 1520 1530 1540 1490 1500 1510 1520 1530 1540 pF1KB9 ISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHS .:::.:::.::::::.::.:::::..:.::::.:...:.::.:::::::::::::::::: XP_016 VSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHS 1550 1560 1570 1580 1590 1600 1550 1560 1570 1580 1590 1600 pF1KB9 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSS ::::::::::::::::::::::::::::::::::::::.:::.::::..:.::: ::::: XP_016 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSS-LTQSS 1610 1620 1630 1640 1650 1660 1610 1620 1630 1640 1650 1660 pF1KB9 CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP :.:::::.....::::.::.:.. .::.::::.::::::::..:: XP_016 CAVTQQMSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQ------------- 1670 1680 1690 1700 1710 1670 1680 1690 1700 1710 1720 pF1KB9 PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPE :.:::: .::: .. :::: XP_016 ---------------------------------------LAQCSMAANFTPPMQLAEIPE 1720 1730 1730 1740 1750 1760 1770 1780 pF1KB9 SGSTGNISIYERI-PGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYA . :..::..:::. .::::: : :::::::::::::::::..: :..::::: :::::: XP_016 T-SNANIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYA 1740 1750 1760 1770 1780 1790 1790 1800 1810 1820 1830 pF1KB9 TSVSLS----NTGLAQLAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATN .:.::: ::::.::. : : . : :::::::::::::. ::: :::: ::.:.: XP_016 NSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASN 1800 1810 1820 1830 1840 1850 1840 1850 1860 1870 1880 1890 pF1KB9 IGIPHTQRLQGQMPVKGHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQR ::: :.:::: :. :::::.:.::: : :.::.::.:.:::: . ::::. :.:..:: XP_016 IGISHSQRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQT-VAMQGPARTLTMQR 1860 1870 1880 1890 1900 1900 1910 1920 1930 1940 1950 pF1KB9 GMNMGVNLMPTPAYNVNS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQM ::::.:::::.::::::: ::::::::::.: :.::::::.:::: .::::: :::::: XP_016 GMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQM 1910 1920 1930 1940 1950 1960 1960 1970 1980 1990 2000 pF1KB9 QMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR ::::::.: :.::::: ::::::::.:.::.:::. :. :::::: :::: XP_016 QMGMMGTQPYAQQPMQTPPHGNMMYTAPGHHGYMNT-GMSKQSLNGSYMRR 1970 1980 1990 2000 2010 >>XP_016871494 (OMIM: 603736,605880,606170) PREDICTED: h (1890 aa) initn: 5014 init1: 1670 opt: 2035 Z-score: 694.7 bits: 142.0 E(85289): 5.9e-32 Smith-Waterman score: 6659; 53.8% identity (72.2% similar) in 2088 aa overlap (1-2004:1-1890) 10 20 30 40 50 60 pF1KB9 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI :::::::::::::::::.:.:::::::::::::.:::.:::::.::: :::::::.::.. XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE :::.:::: ::::::::::.. :: ..:. .. .:::::::..::.::: : XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK .::.::.::..:..:.:... .. : :.:.:::. :::...:::::::: ::.: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC . . : . : : ::::::::::::.: :.:::::::::::::.:::::::::.:: XP_016 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM ::::.::::::::: ::::. :::::::::::::::.:: ::.::::::::::::::::: XP_016 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT :::::::.::::::::::.:::.:::::::..:::::::::..:::::::.::.. : XP_016 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 300 310 320 330 340 350 350 360 370 380 390 pF1KB9 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- ..: .. : .::::.: :. . .:. ..: . :. : : XP_016 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB9 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKRGNRKSSTSD- : .:: ::::::::::::::::::::::..:::..:.:..:: ::. ..:.: .. XP_016 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSH 420 430 440 450 460 470 460 470 480 490 500 pF1KB9 -WPTDNQDGWDGKQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQVRCP ::.. . :::. . ..:.....::.:...:.. :: . .:. . . : : XP_016 VLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP 480 490 500 510 520 530 510 520 530 540 550 560 pF1KB9 SVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANE ::::::::::.:::::::::::.:::::::::::::::::..:: .: :::::::::::: XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE 540 550 560 570 580 590 570 580 590 600 610 620 pF1KB9 IYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLV :::....::::::::.: ::::::::::::::::::::::::::::::::.:: :::::: XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV 600 610 620 630 640 650 630 640 650 660 670 680 pF1KB9 GYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRL ::::::: ::::::::::::.::.::.:.::::::::::::.:::::::::::::::::: XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL 660 670 680 690 700 710 690 700 710 720 730 740 pF1KB9 SYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRR ::.::::::::: :::.....:::: .:. ::.::.::..::.::.:.: :. .:::::: XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR 720 730 740 750 760 770 750 760 770 780 790 800 pF1KB9 EKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGEN--EEPQCQER :::: .:: ::. : ..::. :::::...::..:::::.: .:.: :. .: :. XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK 780 790 800 810 820 830 810 820 830 840 850 860 pF1KB9 ELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGR : :: :... ...: : ::. : . . XP_016 E--------------EQ-----------EILSTRANSRQS---------PAKVQSKNKYL 840 850 860 870 880 890 900 910 920 pF1KB9 WGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQP . ..: . :.. . : : . :: .:. : :. : .:. :.::. ::. XP_016 HSPESRPVT---GERGQLLELSKESSEEEEE--EEDEEEEEEEEEEEEDEEE----EEE- 870 880 890 900 910 930 940 950 960 970 980 pF1KB9 SQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSES XP_016 ------------------------------------------------------------ 990 1000 1010 1020 1030 1040 pF1KB9 SEEEEEPESPRSSSPPILTKP---TLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEV ::::: : .:::: :::: ..:::.::. ...: :::.. ::::.:::::::::: XP_016 -EEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEV 920 930 940 950 960 970 1050 1060 1070 1080 1090 1100 pF1KB9 LDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKS :.:::..:: :::::.:::: :: : ::: . :. :.. : ..::.. XP_016 LNEPFDNSDEERPMPQLEPTCEI---EVEEDGRKPVLRKAFQH---------QPGKKRQT 980 990 1000 1010 1020 1110 1120 1130 1140 1150 1160 pF1KB9 KDEEEDEESDDADDTPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKPIHW :.::. : : . : .: . :. ::: :. :::: .: .: XP_016 ----EEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKW 1030 1040 1050 1060 1070 1170 1180 1190 1200 1210 1220 pF1KB9 KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLP--- .. :: ::::. : . .:: .. ..:..:: : : . : : XP_016 RQNKERKTGFKLNLYTPPETP----MEP-------DEQVTVEEQKETSEGKTS-PSPIRI 1080 1090 1100 1110 1120 1230 1240 1250 1260 1270 pF1KB9 -EERKEEEEMQAEAEEAEEGEEEDAASSEV-PAASPADSSNSPETETKEPEVEEEEEKPR :: :: : :: .. : .: .. :. .: :. .:: : .: : :::::. . XP_016 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1130 1140 1150 1160 1170 1180 1280 1290 1300 1310 pF1KB9 VSEEQRQS---EEE-----QQELEEPE-------------PEEEEDAAAETAQNDDHDAD .::.. . :.. .:: :::: ::::. : ..:.::::: XP_016 EGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1190 1200 1210 1220 1230 1240 1320 1330 1340 1350 1360 1370 pF1KB9 DEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD----- ::::.:.::.. : :: : ::. :: ::.::: :.: .. . . . .: XP_016 DEDDSHMESAEV-EKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASC 1250 1260 1270 1280 1290 1300 1380 1390 1400 1410 1420 pF1KB9 -SEEEQPSHDTSVVSEQ----MAGSEDDHEEDSHTKEELIELKEEEEIPHS-ELDLETVQ :: .. . : .: :. : . ........:: :.:: . : . :.: :::: XP_016 NSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGN--PATMEIDSETVQ 1310 1320 1330 1340 1350 1360 1430 1440 1450 1460 1470 1480 pF1KB9 AVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQM-SMVEDCHASEHNSPISS :::::::: :::.. ..::: :: ::..::.::.::..::. . ..::. :.:.::.:: XP_016 AVQSLTQE-SSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSS 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 1540 pF1KB9 VQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQV :.:::.::::::.::.:::::..:.::::.:...:.::.::::::::::::::::::::: XP_016 VHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQV 1420 1430 1440 1450 1460 1470 1550 1560 1570 1580 1590 1600 pF1KB9 VDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVV :::::::::::::::::::::::::::::::::::.:::.::::..:.::: ::::::.: XP_016 VDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSS-LTQSSCAV 1480 1490 1500 1510 1520 1530 1610 1620 1630 1640 1650 1660 pF1KB9 TQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQ ::::.....::::.::.:.. .::.::::.::::::::..:: XP_016 TQQMSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQ---------------- 1540 1550 1560 1570 1580 1670 1680 1690 1700 1710 1720 pF1KB9 PQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGS :.:::: .::: .. ::::. : XP_016 ------------------------------------LAQCSMAANFTPPMQLAEIPET-S 1590 1600 1730 1740 1750 1760 1770 1780 pF1KB9 TGNISIYERI-PGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSV ..::..:::. .::::: : :::::::::::::::::..: :..::::: ::::::.:. XP_016 NANIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYANSA 1610 1620 1630 1640 1650 1660 1790 1800 1810 1820 1830 pF1KB9 SLS----NTGLAQLAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGI ::: ::::.::. : : . : :::::::::::::. ::: :::: ::.:.:::: XP_016 SLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGI 1670 1680 1690 1700 1710 1720 1840 1850 1860 1870 1880 1890 pF1KB9 PHTQRLQGQMPVKGHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMN :.:::: :. :::::.:.::: : :.::.::.:.:::: . ::::. :.:..::::: XP_016 SHSQRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQT-VAMQGPARTLTMQRGMN 1730 1740 1750 1760 1770 1780 1900 1910 1920 1930 1940 1950 pF1KB9 MGVNLMPTPAYNVNS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMG :.:::::.::::::: ::::::::::.: :.::::::.:::: .::::: ::::::::: XP_016 MSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMG 1790 1800 1810 1820 1830 1840 1960 1970 1980 1990 2000 pF1KB9 MMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR :::.: :.::::: ::::::::.:.::.:::. :. :::::: :::: XP_016 MMGTQPYAQQPMQTPPHGNMMYTAPGHHGYMNT-GMSKQSLNGSYMRR 1850 1860 1870 1880 1890 2004 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:16:04 2016 done: Fri Nov 4 17:16:07 2016 Total Scan time: 19.080 Total Display time: 1.530 Function used was FASTA [36.3.4 Apr, 2011]