FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9572, 788 aa 1>>>pF1KB9572 788 - 788 aa - 788 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6798+/-0.000409; mu= 0.7427+/- 0.025 mean_var=242.7117+/-49.836, 0's: 0 Z-trim(118.7): 90 B-trim: 423 in 2/55 Lambda= 0.082324 statistics sampled from 31872 (31962) to 31872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.375), width: 16 Scan time: 11.320 The best scores are: opt bits E(85289) XP_011542935 (OMIM: 605301) PREDICTED: transformin ( 788) 5129 622.9 1.6e-177 XP_011542934 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122 XP_005273682 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122 XP_011542933 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122 XP_005273685 (OMIM: 605301) PREDICTED: transformin ( 789) 3222 396.4 2.5e-109 XP_005273686 (OMIM: 605301) PREDICTED: transformin ( 781) 3221 396.3 2.7e-109 XP_011542936 (OMIM: 605301) PREDICTED: transformin ( 776) 3196 393.3 2.1e-108 NP_006274 (OMIM: 605301) transforming acidic coile ( 805) 3166 389.8 2.5e-107 XP_016869257 (OMIM: 605301) PREDICTED: transformin ( 748) 2822 348.9 4.7e-95 XP_016869258 (OMIM: 605301) PREDICTED: transformin ( 740) 2821 348.8 5.1e-95 XP_016869255 (OMIM: 605301) PREDICTED: transformin ( 777) 2792 345.3 5.8e-94 XP_016869256 (OMIM: 605301) PREDICTED: transformin ( 769) 2791 345.2 6.2e-94 XP_005273687 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76 XP_016869259 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76 XP_011542937 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76 XP_016869260 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76 XP_016869267 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65 XP_016869265 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65 NP_001317450 (OMIM: 605301) transforming acidic co ( 581) 1996 250.7 1.3e-65 XP_016869266 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65 XP_011542939 (OMIM: 605301) PREDICTED: transformin ( 366) 1956 245.8 2.5e-64 XP_011542940 (OMIM: 605301) PREDICTED: transformin ( 338) 1954 245.6 2.7e-64 XP_016869263 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60 NP_001139688 (OMIM: 605301) transforming acidic co ( 610) 1858 234.3 1.2e-60 XP_016869261 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60 XP_016869262 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60 XP_011542938 (OMIM: 605301) PREDICTED: transformin ( 367) 1568 199.7 1.8e-50 NP_001116296 (OMIM: 605301) transforming acidic co ( 395) 1568 199.8 1.9e-50 XP_006717615 (OMIM: 605302) PREDICTED: transformin (2903) 1003 133.2 1.5e-29 XP_006717617 (OMIM: 605302) PREDICTED: transformin (2887) 990 131.7 4.4e-29 XP_005269449 (OMIM: 605302) PREDICTED: transformin (2969) 990 131.7 4.5e-29 XP_011537435 (OMIM: 605302) PREDICTED: transformin ( 575) 971 129.0 5.8e-29 XP_011537436 (OMIM: 605302) PREDICTED: transformin ( 575) 971 129.0 5.8e-29 NP_001278808 (OMIM: 605302) transforming acidic co ( 575) 971 129.0 5.8e-29 XP_016870988 (OMIM: 605302) PREDICTED: transformin ( 634) 971 129.0 6.3e-29 XP_016870987 (OMIM: 605302) PREDICTED: transformin ( 679) 971 129.0 6.6e-29 XP_016870986 (OMIM: 605302) PREDICTED: transformin ( 679) 971 129.0 6.6e-29 XP_016870985 (OMIM: 605302) PREDICTED: transformin ( 683) 971 129.0 6.7e-29 XP_005269453 (OMIM: 605302) PREDICTED: transformin (2922) 982 130.8 8.6e-29 XP_016870984 (OMIM: 605302) PREDICTED: transformin ( 949) 971 129.1 8.6e-29 XP_016870983 (OMIM: 605302) PREDICTED: transformin ( 966) 971 129.1 8.8e-29 XP_016870982 (OMIM: 605302) PREDICTED: transformin ( 992) 971 129.1 9e-29 NP_996742 (OMIM: 605302) transforming acidic coile ( 996) 971 129.1 9e-29 NP_001278807 (OMIM: 605302) transforming acidic co (1008) 971 129.1 9.1e-29 NP_008928 (OMIM: 605302) transforming acidic coile (1026) 971 129.1 9.2e-29 XP_011537434 (OMIM: 605302) PREDICTED: transformin (1038) 971 129.1 9.3e-29 XP_016870981 (OMIM: 605302) PREDICTED: transformin (1043) 971 129.1 9.3e-29 XP_011537433 (OMIM: 605302) PREDICTED: transformin (1057) 971 129.1 9.4e-29 XP_016870980 (OMIM: 605302) PREDICTED: transformin (1074) 971 129.2 9.5e-29 NP_996743 (OMIM: 605302) transforming acidic coile (1094) 971 129.2 9.7e-29 >>XP_011542935 (OMIM: 605301) PREDICTED: transforming ac (788 aa) initn: 5129 init1: 5129 opt: 5129 Z-score: 3307.9 bits: 622.9 E(85289): 1.6e-177 Smith-Waterman score: 5129; 100.0% identity (100.0% similar) in 788 aa overlap (1-788:1-788) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL 730 740 750 760 770 780 pF1KB9 IAKLGKTD :::::::: XP_011 IAKLGKTD >>XP_011542934 (OMIM: 605301) PREDICTED: transforming ac (817 aa) initn: 3575 init1: 3575 opt: 3596 Z-score: 2323.7 bits: 440.8 E(85289): 1.1e-122 Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE 490 500 510 520 530 540 540 550 560 570 pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG :::::::::::::::::::::::::::::::::: XP_011 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK 730 740 750 760 770 780 760 770 780 pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD ::::::::::::::::::::::::::::::::::::: XP_011 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 790 800 810 >>XP_005273682 (OMIM: 605301) PREDICTED: transforming ac (817 aa) initn: 3575 init1: 3575 opt: 3596 Z-score: 2323.7 bits: 440.8 E(85289): 1.1e-122 Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE 490 500 510 520 530 540 540 550 560 570 pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG :::::::::::::::::::::::::::::::::: XP_005 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK 730 740 750 760 770 780 760 770 780 pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD ::::::::::::::::::::::::::::::::::::: XP_005 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 790 800 810 >>XP_011542933 (OMIM: 605301) PREDICTED: transforming ac (817 aa) initn: 3575 init1: 3575 opt: 3596 Z-score: 2323.7 bits: 440.8 E(85289): 1.1e-122 Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE 490 500 510 520 530 540 540 550 560 570 pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG :::::::::::::::::::::::::::::::::: XP_011 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK 730 740 750 760 770 780 760 770 780 pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD ::::::::::::::::::::::::::::::::::::: XP_011 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 790 800 810 >>XP_005273685 (OMIM: 605301) PREDICTED: transforming ac (789 aa) initn: 3194 init1: 3194 opt: 3222 Z-score: 2083.9 bits: 396.4 E(85289): 2.5e-109 Smith-Waterman score: 4687; 93.6% identity (94.6% similar) in 791 aa overlap (28-788:2-789) 10 20 30 40 50 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEG-DPEEEDSQAETKSLSFSSDSEG : ... :.: .: : :.. .::::: XP_005 MGGSHSQTPRGREPAGERHPRPTET---ASDSEG 10 20 30 60 70 80 90 100 110 pF1KB9 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB9 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB9 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB9 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB9 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEP 460 470 480 490 500 510 540 550 560 570 pF1KB9 ---------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSC ::::::::::::::::::::::::::::::::: XP_005 EEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSC 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 GGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK 640 650 660 670 680 690 700 710 720 730 740 750 pF1KB9 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR 700 710 720 730 740 750 760 770 780 pF1KB9 KEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD :::::::::::::::::::::::::::::::::::::: XP_005 KEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 760 770 780 >>XP_005273686 (OMIM: 605301) PREDICTED: transforming ac (781 aa) initn: 3198 init1: 3198 opt: 3221 Z-score: 2083.3 bits: 396.3 E(85289): 2.7e-109 Smith-Waterman score: 4686; 94.9% identity (95.3% similar) in 779 aa overlap (39-788:5-781) 10 20 30 40 50 60 pF1KB9 LSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAET : :.:.:. : :::::::::::::: XP_005 MFTLPSTLRSNAKTNHQS--SDSEGNFETPEAET 10 20 30 70 80 90 100 110 120 pF1KB9 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB9 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS 400 410 420 430 440 450 490 500 510 520 530 pF1KB9 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFEC 460 470 480 490 500 510 540 550 560 570 pF1KB9 ------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI :::::::::::::::::::::::::::::::::::::::::: XP_005 SNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 CLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 640 650 660 670 680 690 700 710 720 730 740 750 pF1KB9 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 700 710 720 730 740 750 760 770 780 pF1KB9 ERALQQKNQEIEELTKICDELIAKLGKTD ::::::::::::::::::::::::::::: XP_005 ERALQQKNQEIEELTKICDELIAKLGKTD 760 770 780 >>XP_011542936 (OMIM: 605301) PREDICTED: transforming ac (776 aa) initn: 3107 init1: 3107 opt: 3196 Z-score: 2067.3 bits: 393.3 E(85289): 2.1e-108 Smith-Waterman score: 5017; 98.5% identity (98.5% similar) in 788 aa overlap (1-788:1-776) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::: :::: XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCK 430 440 450 460 490 500 510 520 530 540 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB9 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB9 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB9 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB9 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL 710 720 730 740 750 760 pF1KB9 IAKLGKTD :::::::: XP_011 IAKLGKTD 770 >>NP_006274 (OMIM: 605301) transforming acidic coiled-co (805 aa) initn: 4660 init1: 3107 opt: 3166 Z-score: 2047.8 bits: 389.8 E(85289): 2.5e-107 Smith-Waterman score: 4949; 95.0% identity (95.0% similar) in 817 aa overlap (1-788:1-805) 10 20 30 40 50 60 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK :::::::::::::::::::::::::::::::::::::::::::: :::: NP_006 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCK 430 440 450 460 490 500 510 520 530 pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE 470 480 490 500 510 520 540 550 560 570 pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG :::::::::::::::::::::::::::::::::: NP_006 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG 530 540 550 560 570 580 580 590 600 610 620 630 pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 590 600 610 620 630 640 640 650 660 670 680 690 pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 650 660 670 680 690 700 700 710 720 730 740 750 pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK 710 720 730 740 750 760 760 770 780 pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD ::::::::::::::::::::::::::::::::::::: NP_006 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 770 780 790 800 >>XP_016869257 (OMIM: 605301) PREDICTED: transforming ac (748 aa) initn: 2726 init1: 2726 opt: 2822 Z-score: 1827.4 bits: 348.9 E(85289): 4.7e-95 Smith-Waterman score: 4643; 95.5% identity (96.6% similar) in 762 aa overlap (28-788:2-748) 10 20 30 40 50 pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEG-DPEEEDSQAETKSLSFSSDSEG : ... :.: .: : :.. .::::: XP_016 MGGSHSQTPRGREPAGERHPRPTET---ASDSEG 10 20 30 60 70 80 90 100 110 pF1KB9 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB9 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB9 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB9 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC ::::::::::::::::::::::::::::::::::::::::::::: ::: XP_016 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGC 400 410 420 430 480 490 500 510 520 530 pF1KB9 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIE 440 450 460 470 480 490 540 550 560 570 580 590 pF1KB9 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIIT 500 510 520 530 540 550 600 610 620 630 640 650 pF1KB9 KEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQ 560 570 580 590 600 610 660 670 680 690 700 710 pF1KB9 ALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH 620 630 640 650 660 670 720 730 740 750 760 770 pF1KB9 AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE 680 690 700 710 720 730 780 pF1KB9 LIAKLGKTD ::::::::: XP_016 LIAKLGKTD 740 >>XP_016869258 (OMIM: 605301) PREDICTED: transforming ac (740 aa) initn: 2730 init1: 2730 opt: 2821 Z-score: 1826.9 bits: 348.8 E(85289): 5.1e-95 Smith-Waterman score: 4642; 96.9% identity (97.3% similar) in 750 aa overlap (39-788:5-740) 10 20 30 40 50 60 pF1KB9 LSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAET : :.:.:. : :::::::::::::: XP_016 MFTLPSTLRSNAKTNHQS--SDSEGNFETPEAET 10 20 30 70 80 90 100 110 120 pF1KB9 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB9 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS :::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCKVKKHETQS 400 410 420 430 440 490 500 510 520 530 540 pF1KB9 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEKETCQKMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEKETCQKMEE 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB9 DGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWK 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB9 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVE 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB9 RSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB9 EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 690 700 710 720 730 740 788 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:25:10 2016 done: Fri Nov 4 17:25:12 2016 Total Scan time: 11.320 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]