FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9573, 375 aa 1>>>pF1KB9573 375 - 375 aa - 375 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2705+/-0.000383; mu= -4.0942+/- 0.024 mean_var=307.9530+/-61.542, 0's: 0 Z-trim(122.7): 7 B-trim: 376 in 1/56 Lambda= 0.073086 statistics sampled from 41367 (41375) to 41367 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.485), width: 16 Scan time: 9.840 The best scores are: opt bits E(85289) NP_003463 (OMIM: 125264) protein DEK isoform 1 [Ho ( 375) 2379 263.8 4.5e-70 XP_016866762 (OMIM: 125264) PREDICTED: protein DEK ( 380) 2365 262.4 1.3e-69 NP_001128181 (OMIM: 125264) protein DEK isoform 2 ( 341) 1865 209.6 8.7e-54 >>NP_003463 (OMIM: 125264) protein DEK isoform 1 [Homo s (375 aa) initn: 2379 init1: 2379 opt: 2379 Z-score: 1378.9 bits: 263.8 E(85289): 4.5e-70 Smith-Waterman score: 2379; 99.5% identity (100.0% similar) in 375 aa overlap (1-375:1-375) 10 20 30 40 50 60 pF1KB9 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSLKKNVGQFSGFPFEKGSAQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_003 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESSEDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 310 320 330 340 350 360 370 pF1KB9 ERKDFIKTTVKELIS ::::::::::::::: NP_003 ERKDFIKTTVKELIS 370 >>XP_016866762 (OMIM: 125264) PREDICTED: protein DEK iso (380 aa) initn: 2594 init1: 2365 opt: 2365 Z-score: 1370.9 bits: 262.4 E(85289): 1.3e-69 Smith-Waterman score: 2365; 99.2% identity (100.0% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB9 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSLKKNVGQFSGFPFEKGSAQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_016 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESSEDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 310 320 330 340 350 360 370 pF1KB9 ERKDFIKTTVKELIS ::::::::::::. XP_016 ERKDFIKTTVKEVNISVFQV 370 380 >>NP_001128181 (OMIM: 125264) protein DEK isoform 2 [Hom (341 aa) initn: 1859 init1: 1859 opt: 1865 Z-score: 1086.6 bits: 209.6 E(85289): 8.7e-54 Smith-Waterman score: 2096; 90.4% identity (90.9% similar) in 375 aa overlap (1-375:1-341) 10 20 30 40 50 60 pF1KB9 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK------------ 10 20 30 40 70 80 90 100 110 120 pF1KB9 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV :::::::::::::::::::::::::::::::::::::: NP_001 ----------------------GKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 50 60 70 80 130 140 150 160 170 180 pF1KB9 SSLKKNVGQFSGFPFEKGSAQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB9 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 EESSEDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB9 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 270 280 290 300 310 320 370 pF1KB9 ERKDFIKTTVKELIS ::::::::::::::: NP_001 ERKDFIKTTVKELIS 330 340 375 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:25:41 2016 done: Fri Nov 4 17:25:42 2016 Total Scan time: 9.840 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]