FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9574, 380 aa 1>>>pF1KB9574 380 - 380 aa - 380 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6754+/-0.000347; mu= 7.5230+/- 0.022 mean_var=169.8909+/-32.704, 0's: 0 Z-trim(120.7): 49 B-trim: 150 in 1/56 Lambda= 0.098399 statistics sampled from 36307 (36377) to 36307 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.427), width: 16 Scan time: 9.220 The best scores are: opt bits E(85289) NP_005243 (OMIM: 164810) proto-oncogene c-Fos [Hom ( 380) 2507 367.6 2.8e-101 NP_005244 (OMIM: 601575) fos-related antigen 2 [Ho ( 326) 630 101.0 4e-21 XP_016859226 (OMIM: 601575) PREDICTED: fos-related ( 287) 591 95.5 1.7e-19 NP_006723 (OMIM: 164772) protein fosB isoform 1 [H ( 338) 484 80.3 7.2e-15 NP_005429 (OMIM: 136515) fos-related antigen 1 iso ( 271) 468 78.0 2.9e-14 NP_001287785 (OMIM: 136515) fos-related antigen 1 ( 205) 462 77.0 4.3e-14 XP_005264288 (OMIM: 601575) PREDICTED: fos-related ( 205) 457 76.3 7e-14 XP_005258748 (OMIM: 164772) PREDICTED: protein fos ( 237) 451 75.5 1.4e-13 XP_006712039 (OMIM: 601575) PREDICTED: fos-related ( 343) 444 74.7 3.7e-13 XP_006712040 (OMIM: 601575) PREDICTED: fos-related ( 304) 405 69.1 1.6e-11 NP_001193417 (OMIM: 603148) cyclic AMP-dependent t ( 124) 260 48.2 1.3e-05 NP_001193413 (OMIM: 603148) cyclic AMP-dependent t ( 124) 260 48.2 1.3e-05 XP_011507881 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 260 48.3 1.7e-05 NP_001025458 (OMIM: 603148) cyclic AMP-dependent t ( 181) 260 48.3 1.7e-05 XP_005273203 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 260 48.3 1.7e-05 NP_001665 (OMIM: 603148) cyclic AMP-dependent tran ( 181) 260 48.3 1.7e-05 XP_016876462 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 255 47.6 2.5e-05 NP_001128519 (OMIM: 608657) jun dimerization prote ( 163) 255 47.6 2.5e-05 NP_569736 (OMIM: 608657) jun dimerization protein ( 163) 255 47.6 2.5e-05 XP_016876463 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 255 47.6 2.5e-05 XP_005267389 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 255 47.6 2.5e-05 NP_001128520 (OMIM: 608657) jun dimerization prote ( 163) 255 47.6 2.5e-05 XP_016876464 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 255 47.6 2.5e-05 NP_001128521 (OMIM: 608657) jun dimerization prote ( 174) 255 47.6 2.7e-05 XP_016876461 (OMIM: 608657) PREDICTED: jun dimeriz ( 174) 255 47.6 2.7e-05 XP_016876460 (OMIM: 608657) PREDICTED: jun dimeriz ( 206) 255 47.6 3e-05 NP_001107643 (OMIM: 164772) protein fosB isoform 2 ( 302) 242 45.9 0.00015 NP_001287786 (OMIM: 136515) fos-related antigen 1 ( 169) 218 42.3 0.001 NP_001287773 (OMIM: 136515) fos-related antigen 1 ( 235) 213 41.7 0.0021 >>NP_005243 (OMIM: 164810) proto-oncogene c-Fos [Homo sa (380 aa) initn: 2507 init1: 2507 opt: 2507 Z-score: 1939.3 bits: 367.6 E(85289): 2.8e-101 Smith-Waterman score: 2507; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRK 310 320 330 340 350 360 370 380 pF1KB9 GSSSNEPSSDSLSSPTLLAL :::::::::::::::::::: NP_005 GSSSNEPSSDSLSSPTLLAL 370 380 >>NP_005244 (OMIM: 601575) fos-related antigen 2 [Homo s (326 aa) initn: 703 init1: 560 opt: 630 Z-score: 500.1 bits: 101.0 E(85289): 4e-21 Smith-Waterman score: 817; 43.4% identity (65.4% similar) in 396 aa overlap (2-380:1-326) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF :.. . .... .::: ::.::: : :.:.:: :. . : : .:. :.. : NP_005 MYQDYPGNFD-TSSRGSSGSPA-------H--AESYSSGGG--GQQKFRVDMPGSGSAF 10 20 30 40 70 80 90 100 110 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFG-VPA----PSAGAYSRAGVVKTM :::..::.:: ::::.:::....:.. :. ::.. .:. :. : : ::.::. NP_005 IPTINAITTSQDLQWMVQPTVITSMSNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDE . ..::: . :::::::::::::::::::.:::::::::::::. :::::..::.: NP_005 ----GTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEE 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 KSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPES ::.:: :::.: ::::::::.:.:: :.::: ::: .: NP_005 KSGLQKEIAELQKEKEKLEFMLVAHGPVCKIS-----PEERR--------------SP-- 170 180 190 200 240 250 260 270 280 290 pF1KB9 EEAFTLPLLNDPEPKPSVEPVKS----ISSMELKTEPFDDFLFPASSRPSGSETARSV-P : :...:..: .... .: ::... :.:: . ... ::: NP_005 -------------PAPGLQPMRSGGGSVGAVVVKQEPLEE-DSPSSSSAGLDKAQRSVIK 210 220 230 240 300 310 320 330 340 pF1KB9 DMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYP---- ....:.::. ::::. :. ::: ::. : ::..::::: NP_005 PISIAGGFYGE--EPLHT------PI----------VVTSTPAVTPGTSNLVFTYPSVLE 250 260 270 280 350 360 370 380 pF1KB9 -EADSFPS--CAAAHRKGSSSNEPSSDSLSSPTLLAL :. . :: :. :::..:::.. :::::.::::::: NP_005 QESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL 290 300 310 320 >>XP_016859226 (OMIM: 601575) PREDICTED: fos-related ant (287 aa) initn: 676 init1: 533 opt: 591 Z-score: 471.0 bits: 95.5 E(85289): 1.7e-19 Smith-Waterman score: 759; 45.0% identity (66.1% similar) in 342 aa overlap (56-380:4-287) 30 40 50 60 70 80 pF1KB9 SLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSV :.. ::::..::.:: ::::.:::....:. XP_016 MPGSGSAFIPTINAITTSQDLQWMVQPTVITSM 10 20 30 90 100 110 120 130 140 pF1KB9 APSQTRAPHPFG-VPA----PSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKR . :. ::.. .:. :. : : ::.::. . ..::: . ::::::::::: XP_016 SNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI----GTTVGRRRRDEQLSPEEEEKR 40 50 60 70 80 150 160 170 180 190 200 pF1KB9 RIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAH ::::::::.:::::::::::::. :::::..::.:::.:: :::.: ::::::::.:.:: XP_016 RIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAH 90 100 110 120 130 140 210 220 230 240 250 pF1KB9 RPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKS-- :.::: ::: .: : :...:..: XP_016 GPVCKIS-----PEERR--------------SP---------------PAPGLQPMRSGG 150 160 170 260 270 280 290 300 310 pF1KB9 --ISSMELKTEPFDDFLFPASSRPSGSETARSV-PDMDLSGSFYAADWEPLHSGSLGMGP .... .: ::... :.:: . ... ::: ....:.::. ::::. : XP_016 GSVGAVVVKQEPLEE-DSPSSSSAGLDKAQRSVIKPISIAGGFYGE--EPLHT------P 180 190 200 210 220 320 330 340 350 360 pF1KB9 MATELEPLCTPVVTCTPSCTAYTSSFVFTYP-----EADSFPS--CAAAHRKGSSSNEPS . ::: ::. : ::..::::: :. . :: :. :::..:::.. : XP_016 I----------VVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQS 230 240 250 260 270 370 380 pF1KB9 SDSLSSPTLLAL ::::.::::::: XP_016 SDSLNSPTLLAL 280 >>NP_006723 (OMIM: 164772) protein fosB isoform 1 [Homo (338 aa) initn: 711 init1: 440 opt: 484 Z-score: 387.9 bits: 80.3 E(85289): 7.2e-15 Smith-Waterman score: 762; 42.8% identity (64.4% similar) in 404 aa overlap (2-380:1-338) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF ::..: .::. :.::::: ::... : : : .:::.: . . .:. :. :. ..: NP_006 MFQAFPGDYD-SGSRCSS-SPSAE--SQYLSSVDSFGSPPTAAASQE-CAGLGEMPGSF 10 20 30 40 50 70 80 90 100 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQ-----TRAP--HPFGVPA-----PSAGAYSR .::::::.:: ::::::::.:.::.: :: .. : :. .:. :. ..:: NP_006 VPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSS 60 70 80 90 100 110 110 120 130 140 150 pF1KB9 AGVVKT---MTGGRAQSIG---------RRGKVEQLSPEEEEKRRIRRERNKMAAAKCRN .:. . :.: ... : :: . : :.::::::::.::::::.::::::: NP_006 GGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 RRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEM ::::::: :::::::::.::. :..:::.: ::::.:::.:.::.:.:::: . : : NP_006 RRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEG-PGPG 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 SVASL-DLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFP .: . :: : ..: .:..:. :: : : : :: NP_006 PLAEVRDLPG-----SAPAKEDGFSW-LLPPPPPPPL---------------PF------ 240 250 260 280 290 300 310 320 330 pF1KB9 ASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCT .:....: .:..:... :: .: .:. :::. :: NP_006 --------QTSQDAPP-NLTASLFT------HSEVQVLG------DPF--PVVN--PS-- 270 280 290 340 350 360 370 380 pF1KB9 AYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL ::::::.: ::...: :.:.: :.:..:: : :.::.:::: NP_006 -YTSSFVLTCPEVSAF---AGAQRT-SGSDQPS-DPLNSPSLLAL 300 310 320 330 >>NP_005429 (OMIM: 136515) fos-related antigen 1 isoform (271 aa) initn: 677 init1: 422 opt: 468 Z-score: 376.9 bits: 78.0 E(85289): 2.9e-14 Smith-Waterman score: 603; 41.7% identity (57.7% similar) in 324 aa overlap (59-380:36-271) 30 40 50 60 70 80 pF1KB9 YYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPS ...:.....: : .:::.::: ... :: NP_005 GEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG---PS 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB9 QTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNK . :.:. : : : ::.... : .. :: ::.::::::.::.:::::: NP_005 SY--PRPLTYPQYSP-PQPRPGVIRAL--GPPPGV-RRRPCEQISPEEEERRRVRRERNK 70 80 90 100 110 150 160 170 180 190 200 pF1KB9 MAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPD .:::::::::.:::: ::::::.::::::.:: :: .: :.::.::..: :::: ::::. NP_005 LAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPE 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB9 DLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEP :. ::. ...: NP_005 G---------AKEGDTGSTSGTSSP----------------------------------- 180 190 270 280 290 300 310 320 pF1KB9 FDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVV :: :: :: ..:: : ::. : : : ::.. NP_005 ------PAPCRP--------VPCISLS---------P--------GPV-LEPEALHTPTL 200 210 220 330 340 350 360 370 380 pF1KB9 TCTPSCTAYTSSFVFTYPEADSFPS-CAAAHRKGSSSN-EPSSDSLSSPTLLAL ::: : .: :.::::: : : ::.::::.:::. .:::: :.::::::: NP_005 MTTPSLTPFTPSLVFTYP---STPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL 230 240 250 260 270 >>NP_001287785 (OMIM: 136515) fos-related antigen 1 isof (205 aa) initn: 594 init1: 423 opt: 462 Z-score: 374.0 bits: 77.0 E(85289): 4.3e-14 Smith-Waterman score: 531; 43.2% identity (56.1% similar) in 287 aa overlap (96-380:5-205) 70 80 90 100 110 120 pF1KB9 AISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGR :: :.::.: . .: :: :: . NP_001 MFRDFGEPGPSSG--NGGGY-----GGPAQPPAA 10 20 130 140 150 160 170 180 pF1KB9 RGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIAN ..:.::::::.::.::::::.:::::::::.:::: ::::::.::::::.:: :: . NP_001 AQAAQQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEE 30 40 50 60 70 80 190 200 210 220 230 240 pF1KB9 LLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLN : :.::.::..: :::: ::::. :. ::. ...: NP_001 LQKQKERLELVLEAHRPICKIPEG---------AKEGDTGSTSGTSSP------------ 90 100 110 120 250 260 270 280 290 300 pF1KB9 DPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEP :: :: :: ..:: : NP_001 -----------------------------PAPCRP--------VPCISLS---------P 130 140 310 320 330 340 350 360 pF1KB9 LHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPS-CAAAHRKGSSS ::. : : : ::.. ::: : .: :.::::: : : ::.::::.::: NP_001 --------GPV-LEPEALHTPTLMTTPSLTPFTPSLVFTYP---STPEPCASAHRKSSSS 150 160 170 180 370 380 pF1KB9 N-EPSSDSLSSPTLLAL . .:::: :.::::::: NP_001 SGDPSSDPLGSPTLLAL 190 200 >>XP_005264288 (OMIM: 601575) PREDICTED: fos-related ant (205 aa) initn: 453 init1: 396 opt: 457 Z-score: 370.1 bits: 76.3 E(85289): 7e-14 Smith-Waterman score: 476; 49.1% identity (73.7% similar) in 175 aa overlap (2-171:1-158) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF :.. . .... .::: ::.::: : :.:.:: :. . : : .:. :.. : XP_005 MYQDYPGNFD-TSSRGSSGSPA-------H--AESYSSGGG--GQQKFRVDMPGSGSAF 10 20 30 40 70 80 90 100 110 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFG-VPA----PSAGAYSRAGVVKTM :::..::.:: ::::.:::....:.. :. ::.. .:. :. : : ::.::. XP_005 IPTINAITTSQDLQWMVQPTVITSMSNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDE . ..::: . :::::::::::::::::::.:::::::::::::. ::::..: XP_005 ----GTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAEASQKLMT 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 KSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPES XP_005 FVRPLRQTETVFHSGICCPLLNEALARDRGAGGGEVRPAEGDC 170 180 190 200 >>XP_005258748 (OMIM: 164772) PREDICTED: protein fosB is (237 aa) initn: 699 init1: 434 opt: 451 Z-score: 364.7 bits: 75.5 E(85289): 1.4e-13 Smith-Waterman score: 672; 51.3% identity (73.9% similar) in 234 aa overlap (2-211:1-229) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF ::..: .::. :.::::: ::... : : : .:::.: . . .:. :. :. ..: XP_005 MFQAFPGDYD-SGSRCSS-SPSAE--SQYLSSVDSFGSPPTAAASQE-CAGLGEMPGSF 10 20 30 40 50 70 80 90 100 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQ-----TRAP--HPFGVPA-----PSAGAYSR .::::::.:: ::::::::.:.::.: :: .. : :. .:. :. ..:: XP_005 VPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSS 60 70 80 90 100 110 110 120 130 140 150 pF1KB9 AGVVKT---MTGGRAQSIG---------RRGKVEQLSPEEEEKRRIRRERNKMAAAKCRN .:. . :.: ... : :: . : :.::::::::.::::::.::::::: XP_005 GGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 RRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEM ::::::: :::::::::.::. :..:::.: ::::.:::.:.::.:.:::: . : XP_005 RRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 SVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPA XP_005 LAE >>XP_006712039 (OMIM: 601575) PREDICTED: fos-related ant (343 aa) initn: 689 init1: 383 opt: 444 Z-score: 357.1 bits: 74.7 E(85289): 3.7e-13 Smith-Waterman score: 773; 41.6% identity (62.7% similar) in 413 aa overlap (2-380:1-343) 10 20 30 40 50 60 pF1KB9 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF :.. . .... .::: ::.::: : :.:.:: :. . : : .:. :.. : XP_006 MYQDYPGNFD-TSSRGSSGSPA-------H--AESYSSGGG--GQQKFRVDMPGSGSAF 10 20 30 40 70 80 90 100 110 pF1KB9 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFG-VPA----PSAGAYSRAGVVKTM :::..::.:: ::::.:::....:.. :. ::.. .:. :. : : ::.::. XP_006 IPTINAITTSQDLQWMVQPTVITSMSNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI 50 60 70 80 90 100 120 130 140 150 160 pF1KB9 TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQA-------- . ..::: . :::::::::::::::::::.:::::::::::::. ::: XP_006 ----GTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAIGPWQVAV 110 120 130 140 150 160 170 180 190 200 210 pF1KB9 ---------ETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSV ::..::.:::.:: :::.: ::::::::.:.:: :.::: ::: XP_006 PHIPLFPWQETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKIS-----PEERR- 170 180 190 200 210 220 230 240 250 260 270 pF1KB9 ASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKS----ISSMELKTEPFDDFLF .: : :...:..: .... .: ::... XP_006 -------------SP---------------PAPGLQPMRSGGGSVGAVVVKQEPLEE-DS 220 230 240 280 290 300 310 320 330 pF1KB9 PASSRPSGSETARSV-PDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPS :.:: . ... ::: ....:.::. ::::. :. ::: ::. XP_006 PSSSSAGLDKAQRSVIKPISIAGGFYGE--EPLHT------PI----------VVTSTPA 250 260 270 280 340 350 360 370 380 pF1KB9 CTAYTSSFVFTYP-----EADSFPS--CAAAHRKGSSSNEPSSDSLSSPTLLAL : ::..::::: :. . :: :. :::..:::.. :::::.::::::: XP_006 VTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL 290 300 310 320 330 340 >>XP_006712040 (OMIM: 601575) PREDICTED: fos-related ant (304 aa) initn: 662 init1: 356 opt: 405 Z-score: 327.9 bits: 69.1 E(85289): 1.6e-11 Smith-Waterman score: 715; 42.9% identity (63.0% similar) in 359 aa overlap (56-380:4-304) 30 40 50 60 70 80 pF1KB9 SLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSV :.. ::::..::.:: ::::.:::....:. XP_006 MPGSGSAFIPTINAITTSQDLQWMVQPTVITSM 10 20 30 90 100 110 120 130 140 pF1KB9 APSQTRAPHPFG-VPA----PSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKR . :. ::.. .:. :. : : ::.::. . ..::: . ::::::::::: XP_006 SNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI----GTTVGRRRRDEQLSPEEEEKR 40 50 60 70 80 150 160 170 180 pF1KB9 RIRRERNKMAAAKCRNRRRELTDTLQA-----------------ETDQLEDEKSALQTEI ::::::::.:::::::::::::. ::: ::..::.:::.:: :: XP_006 RIRRERNKLAAAKCRNRRRELTEKLQAIGPWQVAVPHIPLFPWQETEELEEEKSGLQKEI 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB9 ANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPL :.: ::::::::.:.:: :.::: ::: .: XP_006 AELQKEKEKLEFMLVAHGPVCKIS-----PEERR--------------SP---------- 150 160 170 250 260 270 280 290 pF1KB9 LNDPEPKPSVEPVKS----ISSMELKTEPFDDFLFPASSRPSGSETARSV-PDMDLSGSF : :...:..: .... .: ::... :.:: . ... ::: ....:.: XP_006 -----PAPGLQPMRSGGGSVGAVVVKQEPLEE-DSPSSSSAGLDKAQRSVIKPISIAGGF 180 190 200 210 220 230 300 310 320 330 340 350 pF1KB9 YAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYP-----EADSFPS :. ::::. :. ::: ::. : ::..::::: :. . :: XP_006 YGE--EPLHT------PI----------VVTSTPAVTPGTSNLVFTYPSVLEQESPASPS 240 250 260 270 360 370 380 pF1KB9 --CAAAHRKGSSSNEPSSDSLSSPTLLAL :. :::..:::.. :::::.::::::: XP_006 ESCSKAHRRSSSSGDQSSDSLNSPTLLAL 280 290 300 380 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:15:32 2016 done: Fri Nov 4 00:15:33 2016 Total Scan time: 9.220 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]