FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9577, 1211 aa 1>>>pF1KB9577 1211 - 1211 aa - 1211 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4743+/-0.000425; mu= 21.2166+/- 0.027 mean_var=73.4169+/-14.955, 0's: 0 Z-trim(110.5): 72 B-trim: 0 in 0/51 Lambda= 0.149684 statistics sampled from 18755 (18830) to 18755 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.571), E-opt: 0.2 (0.221), width: 16 Scan time: 14.850 The best scores are: opt bits E(85289) NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isof (1211) 8085 1756.5 0 XP_005261980 (OMIM: 605794) PREDICTED: RNA helicas (1191) 7879 1712.0 0 XP_016884322 (OMIM: 605794) PREDICTED: RNA helicas (1210) 7517 1633.8 0 NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 i (1165) 7468 1623.2 0 NP_001157576 (OMIM: 605794) RNA helicase Mov10l1 i (1165) 7375 1603.1 0 XP_011529003 (OMIM: 605794) PREDICTED: RNA helicas (1074) 7159 1556.5 0 XP_011528998 (OMIM: 605794) PREDICTED: RNA helicas (1256) 7159 1556.5 0 XP_011528999 (OMIM: 605794) PREDICTED: RNA helicas (1236) 6953 1512.0 0 XP_011529001 (OMIM: 605794) PREDICTED: RNA helicas (1204) 6818 1482.9 0 XP_011529002 (OMIM: 605794) PREDICTED: RNA helicas (1204) 6818 1482.9 0 XP_011529004 (OMIM: 605794) PREDICTED: RNA helicas (1015) 5541 1207.0 0 XP_011529000 (OMIM: 605794) PREDICTED: RNA helicas (1209) 5191 1131.5 0 XP_016884323 (OMIM: 605794) PREDICTED: RNA helicas ( 738) 4597 1003.1 0 XP_011529006 (OMIM: 605794) PREDICTED: RNA helicas ( 690) 4590 1001.6 0 XP_016884326 (OMIM: 605794) PREDICTED: RNA helicas ( 611) 4030 880.6 0 XP_016884325 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 3644 797.3 0 XP_011529005 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 3644 797.3 0 XP_016884324 (OMIM: 605794) PREDICTED: RNA helicas ( 730) 3644 797.3 0 NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 i ( 338) 2254 496.9 8.9e-140 XP_016856808 (OMIM: 610742) PREDICTED: putative he ( 936) 932 211.7 1.8e-53 NP_001273001 (OMIM: 610742) putative helicase MOV- ( 947) 932 211.7 1.8e-53 XP_005270927 (OMIM: 610742) PREDICTED: putative he ( 947) 932 211.7 1.8e-53 XP_005270926 (OMIM: 610742) PREDICTED: putative he ( 947) 932 211.7 1.8e-53 XP_016856807 (OMIM: 610742) PREDICTED: putative he ( 947) 932 211.7 1.8e-53 NP_001308253 (OMIM: 610742) putative helicase MOV- (1003) 932 211.7 1.9e-53 NP_001123551 (OMIM: 610742) putative helicase MOV- (1003) 932 211.7 1.9e-53 NP_066014 (OMIM: 610742) putative helicase MOV-10 (1003) 932 211.7 1.9e-53 NP_002902 (OMIM: 601430) regulator of nonsense tra (1118) 410 99.0 1.8e-19 XP_016882595 (OMIM: 601430) PREDICTED: regulator o (1126) 410 99.0 1.8e-19 NP_001284478 (OMIM: 601430) regulator of nonsense (1129) 410 99.0 1.8e-19 XP_016882594 (OMIM: 601430) PREDICTED: regulator o (1137) 410 99.0 1.8e-19 XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 380 92.4 1.1e-17 XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 380 92.5 1.2e-17 NP_001073918 (OMIM: 601810,615156,615807) DNA repl (1060) 380 92.5 1.5e-17 XP_006717743 (OMIM: 601810,615156,615807) PREDICTE (1090) 380 92.6 1.5e-17 NP_001032412 (OMIM: 611265) helicase with zinc fin (2649) 332 82.4 4.2e-14 XP_006722278 (OMIM: 606699) PREDICTED: probable he (1735) 279 70.9 8.3e-11 XP_011523846 (OMIM: 606699) PREDICTED: probable he (1970) 279 70.9 9.2e-11 XP_006722277 (OMIM: 606699) PREDICTED: probable he (1970) 279 70.9 9.2e-11 XP_006722279 (OMIM: 606699) PREDICTED: probable he (1578) 263 67.4 8.5e-10 XP_016880967 (OMIM: 606699) PREDICTED: probable he (1551) 247 63.9 9.1e-09 NP_001317376 (OMIM: 606699) probable helicase with (1943) 247 64.0 1.1e-08 XP_016880966 (OMIM: 606699) PREDICTED: probable he (1707) 244 63.3 1.5e-08 NP_055692 (OMIM: 606699) probable helicase with zi (1942) 244 63.3 1.7e-08 XP_005257945 (OMIM: 606699) PREDICTED: probable he (1969) 244 63.3 1.7e-08 NP_208384 (OMIM: 611265) helicase with zinc finger (2080) 243 63.1 2.1e-08 XP_011543296 (OMIM: 600502,604320,616155) PREDICTE ( 582) 225 58.9 1.1e-07 XP_005274032 (OMIM: 600502,604320,616155) PREDICTE ( 617) 225 58.9 1.2e-07 XP_011516709 (OMIM: 602433,606002,608465) PREDICTE (2372) 204 54.8 8.1e-06 XP_011516708 (OMIM: 602433,606002,608465) PREDICTE (2413) 204 54.8 8.2e-06 >>NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isoform (1211 aa) initn: 8085 init1: 8085 opt: 8085 Z-score: 9427.5 bits: 1756.5 E(85289): 0 Smith-Waterman score: 8085; 100.0% identity (100.0% similar) in 1211 aa overlap (1-1211:1-1211) 10 20 30 40 50 60 pF1KB9 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 ALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPE 1150 1160 1170 1180 1190 1200 1210 pF1KB9 STGPEKHQEPS ::::::::::: NP_061 STGPEKHQEPS 1210 >>XP_005261980 (OMIM: 605794) PREDICTED: RNA helicase Mo (1191 aa) initn: 7879 init1: 7879 opt: 7879 Z-score: 9187.2 bits: 1712.0 E(85289): 0 Smith-Waterman score: 7879; 100.0% identity (100.0% similar) in 1179 aa overlap (33-1211:13-1191) 10 20 30 40 50 60 pF1KB9 SLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS :::::::::::::::::::::::::::::: XP_005 MSFLPVRSVIGGGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS 10 20 30 40 70 80 90 100 110 120 pF1KB9 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB9 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB9 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB9 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB9 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB9 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB9 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB9 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB9 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB9 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB9 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KB9 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRN 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KB9 VDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKAL 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KB9 LIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPEST 1130 1140 1150 1160 1170 1180 1210 pF1KB9 GPEKHQEPS ::::::::: XP_005 GPEKHQEPS 1190 >>XP_016884322 (OMIM: 605794) PREDICTED: RNA helicase Mo (1210 aa) initn: 7559 init1: 7159 opt: 7517 Z-score: 8764.6 bits: 1633.8 E(85289): 0 Smith-Waterman score: 7584; 92.8% identity (92.8% similar) in 1256 aa overlap (1-1211:1-1210) 10 20 30 40 50 60 pF1KB9 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB9 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQ-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGD 1030 1040 1050 1060 1070 1080 1080 1090 pF1KB9 -------------------------------------VEKIRILLRNVDLMDIKVGSVEE ::::::::::::::::::::::: XP_016 TGASHAEHQVSFMKHVSLWCSHHQAELGKNPQNTEEKVEKIRILLRNVDLMDIKVGSVEE 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB9 FQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRD ::::::::::::: : XP_016 FQGQEYLVIIIST----------------------------------------------D 1150 1160 1170 1180 1190 1200 1210 pF1KB9 PCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS 1160 1170 1180 1190 1200 1210 >>NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 isofo (1165 aa) initn: 7468 init1: 7468 opt: 7468 Z-score: 8707.7 bits: 1623.2 E(85289): 0 Smith-Waterman score: 7468; 100.0% identity (100.0% similar) in 1122 aa overlap (33-1154:13-1134) 10 20 30 40 50 60 pF1KB9 SLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS :::::::::::::::::::::::::::::: NP_001 MSFLPVRSVIGGGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS 10 20 30 40 70 80 90 100 110 120 pF1KB9 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB9 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB9 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB9 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB9 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB9 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB9 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB9 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB9 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB9 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB9 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KB9 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRN 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KB9 VDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKAL 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KB9 LIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPEST :::::::::::: NP_001 LIVLGNPHVLVRLWRGGGRPLLPSGARIHRTREASGAQLICSG 1130 1140 1150 1160 >>NP_001157576 (OMIM: 605794) RNA helicase Mov10l1 isofo (1165 aa) initn: 7375 init1: 7375 opt: 7375 Z-score: 8599.1 bits: 1603.1 E(85289): 0 Smith-Waterman score: 7684; 96.2% identity (96.2% similar) in 1211 aa overlap (1-1211:1-1165) 10 20 30 40 50 60 pF1KB9 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPK :::::::::::::::::::::::::::: NP_001 RNVDLMDIKVGSVEEFQGQEYLVIIIST-------------------------------- 1090 1100 1150 1160 1170 1180 1190 1200 pF1KB9 ALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPE :::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------------DPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPE 1110 1120 1130 1140 1150 1210 pF1KB9 STGPEKHQEPS ::::::::::: NP_001 STGPEKHQEPS 1160 >>XP_011529003 (OMIM: 605794) PREDICTED: RNA helicase Mo (1074 aa) initn: 7159 init1: 7159 opt: 7159 Z-score: 8347.6 bits: 1556.5 E(85289): 0 Smith-Waterman score: 7159; 100.0% identity (100.0% similar) in 1072 aa overlap (1-1072:1-1072) 10 20 30 40 50 60 pF1KB9 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQES 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB9 RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPK >>XP_011528998 (OMIM: 605794) PREDICTED: RNA helicase Mo (1256 aa) initn: 7159 init1: 7159 opt: 7159 Z-score: 8346.6 bits: 1556.5 E(85289): 0 Smith-Waterman score: 7891; 96.4% identity (96.4% similar) in 1243 aa overlap (1-1198:1-1243) 10 20 30 40 50 60 pF1KB9 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPGRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAQKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB9 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQ-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGD 1030 1040 1050 1060 1070 1080 1080 1090 pF1KB9 -------------------------------------VEKIRILLRNVDLMDIKVGSVEE ::::::::::::::::::::::: XP_011 TGASHAEHQVSFMKHVSLWCSHHQAELGKNPQNTEEKVEKIRILLRNVDLMDIKVGSVEE 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB9 FQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRD 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KB9 PCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS ::::::::::::::::::::::::::::::::::::::::::: XP_011 PCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS 1210 1220 1230 1240 1250 >>XP_011528999 (OMIM: 605794) PREDICTED: RNA helicase Mo (1236 aa) initn: 6953 init1: 6953 opt: 6953 Z-score: 8106.3 bits: 1512.0 E(85289): 0 Smith-Waterman score: 7685; 96.3% identity (96.3% similar) in 1211 aa overlap (33-1198:13-1223) 10 20 30 40 50 60 pF1KB9 SLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS :::::::::::::::::::::::::::::: XP_011 MSFLPVRSVIGGGDTKLKTVRGVVTRYCSDYGMIDDMIYFSS 10 20 30 40 70 80 90 100 110 120 pF1KB9 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB9 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRCKELLLLCFSDFLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB9 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKRNSRRQLPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB9 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB9 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEE 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB9 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAE 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB9 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB9 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVK 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB9 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB9 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNP 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB9 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 pF1KB9 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQ---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGDTG 1010 1020 1030 1040 1050 1060 1080 1090 pF1KB9 -----------------------------------VEKIRILLRNVDLMDIKVGSVEEFQ ::::::::::::::::::::::::: XP_011 ASHAEHQVSFMKHVSLWCSHHQAELGKNPQNTEEKVEKIRILLRNVDLMDIKVGSVEEFQ 1070 1080 1090 1100 1110 1120 1100 1110 1120 1130 1140 1150 pF1KB9 GQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPC 1130 1140 1150 1160 1170 1180 1160 1170 1180 1190 1200 1210 pF1KB9 FGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS ::::::::::::::::::::::::::::::::::::::::: XP_011 FGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS 1190 1200 1210 1220 1230 >>XP_011529001 (OMIM: 605794) PREDICTED: RNA helicase Mo (1204 aa) initn: 6818 init1: 6818 opt: 6818 Z-score: 7948.9 bits: 1482.9 E(85289): 0 Smith-Waterman score: 7550; 96.2% identity (96.2% similar) in 1191 aa overlap (53-1198:1-1191) 30 40 50 60 70 80 pF1KB9 AGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSSDAVTSRVLLNVGQEVIAVVE :::::::::::::::::::::::::::::: XP_011 MIDDMIYFSSDAVTSRVLLNVGQEVIAVVE 10 20 30 90 100 110 120 130 140 pF1KB9 ENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIGCVTSLVEGAGCISQTTYFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIGCVTSLVEGAGCISQTTYFSL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 ESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKRVDKVCISSLCGRNGVLEESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKRVDKVCISSLCGRNGVLEESI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 FFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCMTLVKRRDAAPVHEATHFYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCMTLVKRRDAAPVHEATHFYGT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 ILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQNLVSCKLAGWDKSKQFRFQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQNLVSCKLAGWDKSKQFRFQM 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 LDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 ENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNPGRCKELLLLCFSDFLIGRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNPGRCKELLLLCFSDFLIGRYL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFLPQYPIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFLPQYPIPD 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 RLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEEIYAEMELKEYNMSGIILRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEEIYAEMELKEYNMSGIILRRN 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB9 GDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYISYVTEIHEEDVTLKINPEFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYISYVTEIHEEDVTLKINPEFEQ 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB9 AYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEEIILQSPQVTGNWNHAQDTKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEEIILQSPQVTGNWNHAQDTKS 580 590 600 610 620 630 690 700 710 720 730 740 pF1KB9 SGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEIQTPKARKMEFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEIQTPKARKMEFFN 640 650 660 670 680 690 750 760 770 780 790 800 pF1KB9 PVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPS 700 710 720 730 740 750 810 820 830 840 850 860 pF1KB9 NSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIIT 760 770 780 790 800 810 870 880 890 900 910 920 pF1KB9 TCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPV 820 830 840 850 860 870 930 940 950 960 970 980 pF1KB9 IKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLP 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KB9 SRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQ 940 950 960 970 980 990 1050 1060 1070 pF1KB9 VLRYCCLLAHSISSQVSASDIGVITPYRKQ------------------------------ :::::::::::::::::::::::::::::: XP_011 VLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGDTGASHAEHQVSFMKHVSLWCSH 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 pF1KB9 ---------------VEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFE ::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQAELGKNPQNTEEKVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFE 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLP 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 pF1KB9 PALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS ::::::::::::::::::::: XP_011 PALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS 1180 1190 1200 >>XP_011529002 (OMIM: 605794) PREDICTED: RNA helicase Mo (1204 aa) initn: 6818 init1: 6818 opt: 6818 Z-score: 7948.9 bits: 1482.9 E(85289): 0 Smith-Waterman score: 7550; 96.2% identity (96.2% similar) in 1191 aa overlap (53-1198:1-1191) 30 40 50 60 70 80 pF1KB9 AGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSSDAVTSRVLLNVGQEVIAVVE :::::::::::::::::::::::::::::: XP_011 MIDDMIYFSSDAVTSRVLLNVGQEVIAVVE 10 20 30 90 100 110 120 130 140 pF1KB9 ENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIGCVTSLVEGAGCISQTTYFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENKVSNGLKAIRVEAVSDKWEDDSRNHGSPSDCGPRVLIGCVTSLVEGAGCISQTTYFSL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 ESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKRVDKVCISSLCGRNGVLEESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKRVDKVCISSLCGRNGVLEESI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 FFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCMTLVKRRDAAPVHEATHFYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCMTLVKRRDAAPVHEATHFYGT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 ILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQNLVSCKLAGWDKSKQFRFQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQNLVSCKLAGWDKSKQFRFQM 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 LDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 ENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNPGRCKELLLLCFSDFLIGRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNPGRCKELLLLCFSDFLIGRYL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFLPQYPIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFLPQYPIPD 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 RLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEEIYAEMELKEYNMSGIILRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLRKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEEIYAEMELKEYNMSGIILRRN 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB9 GDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYISYVTEIHEEDVTLKINPEFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYISYVTEIHEEDVTLKINPEFEQ 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB9 AYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEEIILQSPQVTGNWNHAQDTKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVLFPEEIILQSPQVTGNWNHAQDTKS 580 590 600 610 620 630 690 700 710 720 730 740 pF1KB9 SGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEIQTPKARKMEFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEIQTPKARKMEFFN 640 650 660 670 680 690 750 760 770 780 790 800 pF1KB9 PVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPS 700 710 720 730 740 750 810 820 830 840 850 860 pF1KB9 NSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIIT 760 770 780 790 800 810 870 880 890 900 910 920 pF1KB9 TCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPV 820 830 840 850 860 870 930 940 950 960 970 980 pF1KB9 IKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLP 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KB9 SRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQ 940 950 960 970 980 990 1050 1060 1070 pF1KB9 VLRYCCLLAHSISSQVSASDIGVITPYRKQ------------------------------ :::::::::::::::::::::::::::::: XP_011 VLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGDTGASHAEHQVSFMKHVSLWCSH 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 pF1KB9 ---------------VEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFE ::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQAELGKNPQNTEEKVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFE 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KB9 DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLP 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 pF1KB9 PALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS ::::::::::::::::::::: XP_011 PALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS 1180 1190 1200 1211 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:26:58 2016 done: Fri Nov 4 17:27:00 2016 Total Scan time: 14.850 Total Display time: 0.600 Function used was FASTA [36.3.4 Apr, 2011]