FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9584, 270 aa
1>>>pF1KB9584 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8436+/-0.000366; mu= 0.9166+/- 0.023
mean_var=268.7335+/-54.966, 0's: 0 Z-trim(122.7): 19 B-trim: 0 in 0/52
Lambda= 0.078237
statistics sampled from 41353 (41376) to 41353 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.485), width: 16
Scan time: 6.920
The best scores are: opt bits E(85289)
NP_001161860 (OMIM: 602937,614431,614433) cbp/p300 ( 270) 1944 231.8 1.1e-60
NP_006070 (OMIM: 602937,614431,614433) cbp/p300-in ( 270) 1944 231.8 1.1e-60
NP_001161861 (OMIM: 602937,614431,614433) cbp/p300 ( 275) 1944 231.8 1.1e-60
NP_001138359 (OMIM: 300149) cbp/p300-interacting t ( 193) 258 41.3 0.0016
NP_004134 (OMIM: 300149) cbp/p300-interacting tran ( 193) 258 41.3 0.0016
NP_001138358 (OMIM: 300149) cbp/p300-interacting t ( 193) 258 41.3 0.0016
XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-in ( 219) 258 41.4 0.0018
NP_001138357 (OMIM: 300149) cbp/p300-interacting t ( 219) 258 41.4 0.0018
>>NP_001161860 (OMIM: 602937,614431,614433) cbp/p300-int (270 aa)
initn: 1944 init1: 1944 opt: 1944 Z-score: 1210.7 bits: 231.8 E(85289): 1.1e-60
Smith-Waterman score: 1944; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KB9 MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRI
190 200 210 220 230 240
250 260 270
pF1KB9 KELPELWLGQNEFDFMTDFVCKQQPSRVSC
::::::::::::::::::::::::::::::
NP_001 KELPELWLGQNEFDFMTDFVCKQQPSRVSC
250 260 270
>>NP_006070 (OMIM: 602937,614431,614433) cbp/p300-intera (270 aa)
initn: 1944 init1: 1944 opt: 1944 Z-score: 1210.7 bits: 231.8 E(85289): 1.1e-60
Smith-Waterman score: 1944; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KB9 MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRI
190 200 210 220 230 240
250 260 270
pF1KB9 KELPELWLGQNEFDFMTDFVCKQQPSRVSC
::::::::::::::::::::::::::::::
NP_006 KELPELWLGQNEFDFMTDFVCKQQPSRVSC
250 260 270
>>NP_001161861 (OMIM: 602937,614431,614433) cbp/p300-int (275 aa)
initn: 1944 init1: 1944 opt: 1944 Z-score: 1210.6 bits: 231.8 E(85289): 1.1e-60
Smith-Waterman score: 1944; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:6-275)
10 20 30 40 50
pF1KB9 MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGLEMADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 IHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 LQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSST
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PGGSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEM
190 200 210 220 230 240
240 250 260 270
pF1KB9 GLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:::::::::::::::::::::::::::::::::::
NP_001 GLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
250 260 270
>>NP_001138359 (OMIM: 300149) cbp/p300-interacting trans (193 aa)
initn: 308 init1: 248 opt: 258 Z-score: 184.1 bits: 41.3 E(85289): 0.0016
Smith-Waterman score: 310; 36.0% identity (59.3% similar) in 172 aa overlap (89-259:48-189)
60 70 80 90 100 110
pF1KB9 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
:.. :... : :..:.:. . .
NP_001 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB9 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSG-GSSTPGGSGGSSTPG
. :: :: : : . .. :.. : ...: ...::: ::
NP_001 TKPPSFNLHPAP--HLLASM-------------HLQKLNSQYQGMAAATPG------QPG
80 90 100 110
180 190 200 210 220 230
pF1KB9 GSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGL
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::
NP_001 EAGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGL
120 130 140 150 160
240 250 260 270
pF1KB9 DRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:: .:::::::::::::: .::
NP_001 DRANELPELWLGQNEFDFTADFPSSC
170 180 190
>>NP_004134 (OMIM: 300149) cbp/p300-interacting transact (193 aa)
initn: 308 init1: 248 opt: 258 Z-score: 184.1 bits: 41.3 E(85289): 0.0016
Smith-Waterman score: 310; 36.0% identity (59.3% similar) in 172 aa overlap (89-259:48-189)
60 70 80 90 100 110
pF1KB9 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
:.. :... : :..:.:. . .
NP_004 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB9 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSG-GSSTPGGSGGSSTPG
. :: :: : : . .. :.. : ...: ...::: ::
NP_004 TKPPSFNLHPAP--HLLASM-------------HLQKLNSQYQGMAAATPG------QPG
80 90 100 110
180 190 200 210 220 230
pF1KB9 GSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGL
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::
NP_004 EAGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGL
120 130 140 150 160
240 250 260 270
pF1KB9 DRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:: .:::::::::::::: .::
NP_004 DRANELPELWLGQNEFDFTADFPSSC
170 180 190
>>NP_001138358 (OMIM: 300149) cbp/p300-interacting trans (193 aa)
initn: 308 init1: 248 opt: 258 Z-score: 184.1 bits: 41.3 E(85289): 0.0016
Smith-Waterman score: 310; 36.0% identity (59.3% similar) in 172 aa overlap (89-259:48-189)
60 70 80 90 100 110
pF1KB9 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
:.. :... : :..:.:. . .
NP_001 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB9 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSG-GSSTPGGSGGSSTPG
. :: :: : : . .. :.. : ...: ...::: ::
NP_001 TKPPSFNLHPAP--HLLASM-------------HLQKLNSQYQGMAAATPG------QPG
80 90 100 110
180 190 200 210 220 230
pF1KB9 GSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGL
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::
NP_001 EAGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGL
120 130 140 150 160
240 250 260 270
pF1KB9 DRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:: .:::::::::::::: .::
NP_001 DRANELPELWLGQNEFDFTADFPSSC
170 180 190
>>XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-intera (219 aa)
initn: 308 init1: 248 opt: 258 Z-score: 183.4 bits: 41.4 E(85289): 0.0018
Smith-Waterman score: 310; 36.0% identity (59.3% similar) in 172 aa overlap (89-259:74-215)
60 70 80 90 100 110
pF1KB9 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
:.. :... : :..:.:. . .
XP_011 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSG-GSSTPGGSGGSSTPG
. :: :: : : . .. :.. : ...: ...::: ::
XP_011 TKPPSFNLHPAP--HLLASM-------------HLQKLNSQYQGMAAATPG------QPG
110 120 130 140
180 190 200 210 220 230
pF1KB9 GSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGL
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::
XP_011 EAGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGL
150 160 170 180 190
240 250 260 270
pF1KB9 DRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:: .:::::::::::::: .::
XP_011 DRANELPELWLGQNEFDFTADFPSSC
200 210
>>NP_001138357 (OMIM: 300149) cbp/p300-interacting trans (219 aa)
initn: 308 init1: 248 opt: 258 Z-score: 183.4 bits: 41.4 E(85289): 0.0018
Smith-Waterman score: 310; 36.0% identity (59.3% similar) in 172 aa overlap (89-259:74-215)
60 70 80 90 100 110
pF1KB9 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
:.. :... : :..:.:. . .
NP_001 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSG-GSSTPGGSGGSSTPG
. :: :: : : . .. :.. : ...: ...::: ::
NP_001 TKPPSFNLHPAP--HLLASM-------------HLQKLNSQYQGMAAATPG------QPG
110 120 130 140
180 190 200 210 220 230
pF1KB9 GSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGL
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.::
NP_001 EAGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGL
150 160 170 180 190
240 250 260 270
pF1KB9 DRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
:: .:::::::::::::: .::
NP_001 DRANELPELWLGQNEFDFTADFPSSC
200 210
270 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:29:40 2016 done: Fri Nov 4 17:29:41 2016
Total Scan time: 6.920 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]