FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9593, 330 aa 1>>>pF1KB9593 330 - 330 aa - 330 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0444+/-0.000322; mu= -5.0631+/- 0.020 mean_var=266.3602+/-53.924, 0's: 0 Z-trim(124.8): 133 B-trim: 0 in 0/58 Lambda= 0.078585 statistics sampled from 47008 (47153) to 47008 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.553), width: 16 Scan time: 9.350 The best scores are: opt bits E(85289) NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 2373 281.4 1.8e-75 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 655 86.8 1.1e-16 NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 623 83.1 1.3e-15 NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 584 78.7 2.8e-14 NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 565 76.4 8.8e-14 NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 556 75.4 1.9e-13 NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 556 75.5 2e-13 NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 555 75.4 2.2e-13 NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 557 75.6 2.2e-13 NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 552 75.0 3e-13 NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 519 71.3 4e-12 NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 517 71.1 4.7e-12 NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 514 70.8 6.2e-12 NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 514 70.8 6.6e-12 NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 507 70.0 1.1e-11 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 505 69.7 1.1e-11 NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 503 69.5 1.4e-11 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 494 68.4 2.5e-11 XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 491 68.1 3.8e-11 NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 491 68.2 4e-11 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 487 67.6 4.6e-11 NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 473 66.1 1.6e-10 NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 473 66.1 1.6e-10 NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 471 65.9 1.7e-10 NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 465 65.2 3.2e-10 XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 437 62.1 3.2e-09 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 437 62.2 4e-09 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 430 61.2 4.4e-09 NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 390 56.8 1.5e-07 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 363 53.7 1.1e-06 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 363 53.7 1.1e-06 XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 363 53.7 1.1e-06 NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 347 51.8 2.7e-06 XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 345 51.7 4.7e-06 NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 345 51.7 4.8e-06 NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 345 51.7 4.8e-06 NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 345 51.7 4.8e-06 XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 345 51.7 4.8e-06 XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 345 51.7 4.8e-06 NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 322 48.9 1.6e-05 NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 301 46.6 0.00012 XP_011519236 (OMIM: 602341) PREDICTED: forkhead bo ( 433) 283 44.6 0.00047 XP_011519237 (OMIM: 602341) PREDICTED: forkhead bo ( 422) 281 44.3 0.00054 NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 281 44.4 0.00061 NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 276 43.8 0.00081 XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 276 43.8 0.00081 XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 276 43.8 0.00081 XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 276 43.8 0.00081 XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 276 43.8 0.00081 XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 276 43.8 0.00081 >>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa) initn: 2373 init1: 2373 opt: 2373 Z-score: 1476.0 bits: 281.4 E(85289): 1.8e-75 Smith-Waterman score: 2373; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB9 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TTDGRPRPPMEPKEISTPKPACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TTDGRPRPPMEPKEISTPKPACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWV 250 260 270 280 290 300 310 320 330 pF1KB9 AGGFPVQGGSGYPLGLTPCLYRTPGMFFFE :::::::::::::::::::::::::::::: NP_004 AGGFPVQGGSGYPLGLTPCLYRTPGMFFFE 310 320 330 >>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa) initn: 658 init1: 571 opt: 655 Z-score: 420.2 bits: 86.8 E(85289): 1.1e-16 Smith-Waterman score: 684; 44.6% identity (62.2% similar) in 278 aa overlap (8-282:65-301) 10 20 30 pF1KB9 MQQQPLPGPGAPTTEP---TKPPYSYIALIAMAIQSS :: .: .: .::::::::::.::::.. NP_001 GGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNA 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB9 PGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTL : .. ::.:::..:: :: ::: :. :::::::::::::::::::::::.:::::::::: NP_001 PDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTL 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB9 DPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSF ::: ..:::.:::::::::: .. . .: .. : ..: : ::: NP_001 DPDSYNMFENGSFLRRRRRFKKKDA-------VKDKEEKDRLHLKEPPPP----GRQ--- 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 PPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGELPVATSSSS :: : : . :. : .: ::.. ..:.: . .::. : : .. NP_001 PP--PAPPEQADGNAPGPQP-------------PPVRIQDIKTENGTCPSP-PQPLSPAA 210 220 230 240 220 230 240 250 260 270 pF1KB9 CPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAP . : :. . :: ... . . : : :: . : .:. ::: :: : NP_001 ALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLD---GAD--------SAPP 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE ::: .:: NP_001 PPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAY 300 310 320 330 340 350 >>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa) initn: 622 init1: 570 opt: 623 Z-score: 401.2 bits: 83.1 E(85289): 1.3e-15 Smith-Waterman score: 644; 37.7% identity (60.5% similar) in 342 aa overlap (9-318:64-402) 10 20 30 pF1KB9 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQR :.:: . .::::::::::.::::..: .. NP_005 MASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPK-DLVKPPYSYIALITMAIQNAPEKK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB9 ATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDC ::.:::..:: :: :::.:. :::::::::::::::::::::::.::::::::::::: NP_005 ITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDS 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB9 HDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPEL ..:::.:::::::::: .. .. . :. .. : :.. :..:. . . . . . NP_005 YNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVV 160 170 180 190 200 210 160 170 180 190 200 pF1KB9 PDPKGLSFGGLVGAMPASMCPATT-DGRPRP----PMEPKEISTPK--PACPGELP---- .. : . : . .. : .. .: :: : . : :. : :. :: NP_005 IKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGFSV 220 230 240 250 260 270 210 220 230 240 250 pF1KB9 --VATSSSSCPAFGFPAGFSEAE--------SFNKAPTPVLS-P-----ESGIGSSYQCR . : .: :. . : ..: . :: . . : :.: ...::: NP_005 ENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCS 280 290 300 310 320 330 260 270 280 290 300 pF1KB9 LQALNFCMGAD-PGLEHLLASAAPSPA---PPTPPGSLRAPLPLPTDHKEPWVAGGFPVQ ..:... ::. :. :. . : . : :. : : . : : . .. .: : : NP_005 MRAMSLYTGAERPA--HMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQ 340 350 360 370 380 390 310 320 330 pF1KB9 G-GSGYPLGLTPCLYRTPGMFFFE : .: . : NP_005 HHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNV 400 410 420 430 440 450 >>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa) initn: 552 init1: 500 opt: 584 Z-score: 377.4 bits: 78.7 E(85289): 2.8e-14 Smith-Waterman score: 611; 40.2% identity (57.9% similar) in 323 aa overlap (5-318:110-410) 10 20 30 pF1KB9 MQQQPLPGP---GAPTTEP-TKPPYSYIALIAMA : ::: :: : : .::::::::::.:: NP_004 GEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPLVKPPYSYIALITMA 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB9 IQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGS : .:: .: ::: : ..: ::: .::.. :.::::::::::::.::::.::. .::::. NP_004 ILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGN 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB9 YWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGR ::::::. :::..:::::::.:: :: : . ::. . : :.: NP_004 YWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGA---- 200 210 220 230 240 250 160 170 180 190 200 pF1KB9 QCSFPPELPDPKGLSFG-GLVGAMPASMCPATTDGRPRPPMEPKEIS--TPKPACPGELP : : . . ..: :: :.:: : . :.: .:. .. . : : .: NP_004 ---FLPGFAAYGAYGYGYGL--ALPAYGAPPPGPA-PHPHPHPHAFAFAAAAAAAPCQLS 260 270 280 290 300 210 220 230 240 250 260 pF1KB9 VATSSSSCPAFGFPAG--FSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGL : . .. : : :.. :. : : ::.: .: :: : . .: .::. : NP_004 VPPGRAAAPPPGPPTASVFAGAGS---APAP--APASGSGPGPGP--AGLPAFLGAELGC 310 320 330 340 350 360 270 280 290 300 310 320 pF1KB9 EHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPG . : : : .::. . : : . . ..:: ::.: : : NP_004 AK--AFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGG---AGGGGAGAGQRPSFSIDHI 370 380 390 400 410 330 pF1KB9 MFFFE NP_004 MGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALL 420 430 440 450 460 470 >>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa) initn: 523 init1: 492 opt: 565 Z-score: 368.4 bits: 76.4 E(85289): 8.8e-14 Smith-Waterman score: 573; 39.5% identity (55.7% similar) in 291 aa overlap (5-288:55-309) 10 20 30 pF1KB9 MQQQPLPGPGAPTTEPT---KPPYSYIALIAMAI : :::: .: :::::::::::::. NP_036 SGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMAL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 QSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSY .::.: ::..:::.: :::::: . :::::::::.::.:::::::. .::::.: NP_036 AHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 WTLDPDCHDMFEHGSFLRRRRRFTR-QTGAEGTRGPAKARRGPLRATSQDPGVPNATTGR ::::: :::..:::::::.:: : . :... .:. : . :: : . NP_036 WTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPG-PALLVPP 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 QCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGELPVAT . : : . .: .::. .: . : :.: : : . .:. NP_036 PSAGPGPSPPARLFSVDSLVNLQPE----LAGLGAPEP-----------PCCAAPDAAAA 210 220 230 240 220 230 240 250 260 270 pF1KB9 SSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLA . : : . : .:.. .. :. : : : . :.: ::: NP_036 AFPPCAAAASPPLYSQVP--DRLVLPATRP--GPGP------------LPAEP----LLA 250 260 270 280 280 290 300 310 320 pF1KB9 SAAPSPA-PPTPPGS--LRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMF :.:. : : :: :: : NP_036 LAGPAAALGPLSPGEAYLRQPGFASGLERYL 290 300 310 >>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa) initn: 559 init1: 538 opt: 556 Z-score: 362.4 bits: 75.4 E(85289): 1.9e-13 Smith-Waterman score: 601; 41.0% identity (58.7% similar) in 317 aa overlap (16-324:47-334) 10 20 30 40 pF1KB9 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIY : :::::::::::::::..: ::.::.::: NP_005 MLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIY 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB9 RYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHG ..:: :: ::. :: :::::::::::::.:::::::. .::::::::::: : ::::.: NP_005 QFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENG 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB9 SFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLS .. ::.:. :: .. : .:. : .: :.: .: : : ..: NP_005 NYRRRKRKPKPGPGAPEAKRP-RAETHQRSAEAQ----PEAGSGAGGSGP-------AIS 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 FGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGE-LPVATSSSSCPAFGFPAGF . : ::. : :: : :: : . : : :.: :..... : : : NP_005 R---LQAAPAGPSP-LLDG-PSPPA-P--LHWPGTASPNEDAGDAAQGAAAVAVGQAART 190 200 210 220 230 230 240 250 260 270 pF1KB9 SEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADP-GLEHLLASAAPSPAPP---- ... . :. ::.:. :. . : .: : . ..::..: :.:. NP_005 GDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGAS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 --TPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE . .::: :. . .: : ::: : ::. : : : NP_005 LLAASSSLRPPFN-ASLMLDPHVQGGF-------YQLGI-PFLSYFPLQVPDTVLHFQ 300 310 320 330 340 >>NP_075555 (OMIM: 110100,605597,608996) forkhead box pr (376 aa) initn: 556 init1: 471 opt: 556 Z-score: 361.9 bits: 75.5 E(85289): 2e-13 Smith-Waterman score: 560; 36.2% identity (55.3% similar) in 340 aa overlap (5-321:32-360) 10 20 pF1KB9 MQQQPLPGPG-------APTT-EPT-KPPYSYIA : :: : :: .:. ::::::.: NP_075 MASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVA 10 20 30 40 50 60 30 40 50 60 70 80 pF1KB9 LIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRK ::::::. : .: ::::::.::...: ::..:. ::::::::::::::::.::::. NP_075 LIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGG 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 PGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTR-GPAKARRGPLRATSQDPGVP ::.:::::: :.::::.:.. :::::. : .. :.:. : :.. :: NP_075 ERKGNYWTLDPACEDMFEKGNY-RRRRRMKRPFRPPPAHFQPGKGLFGAGGAAG-GCGVA 130 140 150 160 170 150 160 170 180 190 pF1KB9 NATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCP-----ATTDGRPRPPMEPKEISTPK .: . . : :: :. : : .. : . : :. . .. NP_075 GAGADGYGYLAP----PKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAG 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB9 PACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCM :. :: :. . .. :: .. . .....:. : :.. .:.:. . NP_075 PGSPGAAAVVKGLAG-PAASY-GPYTRVQSMA-LPPGVVNSYNGLGGPPAAPPPPPH--P 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB9 GADPGLEHLLASAAPSPAPP------TPPGSLR--APLPLPTDHKEPWVAGGFPVQGGSG : .:: :.::: :::: :::.: .: : : :. . NP_075 HPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQ 300 310 320 330 340 350 320 330 pF1KB9 YPLGLTPCLYRTPGMFFFE :.. : : NP_075 PELAMMHCSYWDHDSKTGALHSRLDL 360 370 >>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa) initn: 524 init1: 489 opt: 555 Z-score: 361.3 bits: 75.4 E(85289): 2.2e-13 Smith-Waterman score: 555; 36.7% identity (57.2% similar) in 313 aa overlap (18-315:53-344) 10 20 30 40 pF1KB9 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRY :::::::::::::: .: .: ::.:::.. NP_004 GETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKF 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB9 IMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSF : :: ::: : :::::::::.::.::.:.::. .::::.::.:::. .:::: ::: NP_004 ITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSF 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB9 LRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFG ::::.:: : .. . :: . . :.. .. :. . : : : .. NP_004 LRRRKRFKR---SDLSTYPAYMHDAAAAAAAAAAAAAAAAI-FPGAVPAARPPYPGAVYA 150 160 170 180 190 170 180 190 200 210 pF1KB9 GL----VGAMPASMCPATTDGR-------PRPPMEPKEISTPKPACPGELPVATSSSSCP : ..: : . ::.. : :. :. : :.. : :. :: : .:.. : NP_004 GYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSP-ELG-PAPSGPGG-SCAFASAGAP 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 AF--GF-PAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAA : :. ::: . :. : :. . .: ..: .:: . ..:.:. NP_004 ATTTGYQPAGCTGARPAN--PSAYAAAYAGPDGAYP---------QGAGSA---IFAAAG 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 PSPAPPTPP-GSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE .: .:: :. . . .: : : . :. : : NP_004 RLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAA 310 320 330 340 350 360 NP_004 YPGGIDRFVSAM 370 >>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa) initn: 539 init1: 500 opt: 557 Z-score: 361.2 bits: 75.6 E(85289): 2.2e-13 Smith-Waterman score: 570; 39.2% identity (57.3% similar) in 309 aa overlap (10-284:116-405) 10 20 30 pF1KB9 MQQQPLPGPGAPTTEP-TKPPYSYIALIAMAIQSSPGQR :. . .: .::::::::::.::: .:: .: NP_004 SPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKR 90 100 110 120 130 140 40 50 60 70 80 90 pF1KB9 ATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDC ::: : ..: ::: .::.. :.::::::::::::.::::.::. .::::.::::::. NP_004 LTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPES 150 160 170 180 190 200 100 110 120 130 140 pF1KB9 HDMFEHGSFLRRRRRFTRQ-----------------TGAEGTRG-PAKARRGPLRATSQD :::..:::::::.:: :: .:: : : :: : : NP_004 ADMFDNGSFLRRRKRFKRQPLLPPNAAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPP 210 220 230 240 250 260 150 160 170 180 190 pF1KB9 P---GVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEIST : : : ..:: : :..: .. ..: :.. : . : : :.. NP_004 PHAYGYGPYGCGYGLQLPPYAP-PSALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELAR 270 280 290 300 310 320 200 210 220 230 240 pF1KB9 ------PKP---ACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSY :.: : :: ::....... :. : .. ..: .: :: ::.: NP_004 TAFGYRPHPLGAALPGPLPASAAKAGGPG---------ASALARSP---FSIESIIGGSL 330 340 350 360 370 250 260 270 280 290 300 pF1KB9 QCRLQALNFCMGADPGLEHLLASAAPSPAP---PTPPGSLRAPLPLPTDHKEPWVAGGFP : ..: :.:.:::.: : ::: NP_004 GPAAAAAAAAQAAAA------AQASPSPSPVAAPPAPGSSGGGCAAQAAVGPAAALTRSL 380 390 400 410 420 310 320 330 pF1KB9 VQGGSGYPLGLTPCLYRTPGMFFFE NP_004 VAAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC 430 440 450 460 >>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa) initn: 558 init1: 516 opt: 552 Z-score: 359.0 bits: 75.0 E(85289): 3e-13 Smith-Waterman score: 560; 39.9% identity (59.0% similar) in 288 aa overlap (15-285:104-361) 10 20 30 40 pF1KB9 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGI .:.::::::::::.::: .:: .: ::::: NP_036 IEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGI 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB9 YRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEH .: ::: .::.. :.::::::::::::.::::.::. .::::.::.::: .:::.. NP_036 CAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDN 140 150 160 170 180 190 110 120 130 140 150 160 pF1KB9 GSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGL :::::::.:: :. . :.. : .:. ..: :. : : ::.: NP_036 GSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPR-PGPLLG-----APALPQP--- 200 210 220 230 240 170 180 190 200 210 pF1KB9 SFGGLVGAMPASMCPATTDG---RPRPPM-----EPKEISTPKPA------CPGELPVAT . ::.: . :. .:.:: : ..:: : :: ::: NP_036 ----VPGAYPNTA-PGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ 250 260 270 280 290 220 230 240 250 260 pF1KB9 SSSSCPAFGFPAGFSEAESFNKAPTPVLSPESG--IGSSYQCRLQALNFCMGADPGLEHL :..: : . :.... :: .: :. : . .:.. :: : . NP_036 -----PSLG-PQPWEEGKGLA-------SPPGGGCISFSIESIMQGVR---GAGTGAAQS 300 310 320 330 340 270 280 290 300 310 320 pF1KB9 LASAAPSPAPPTP-PGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMF :. .: : : :.:: NP_036 LSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSG 350 360 370 380 390 400 330 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:34:16 2016 done: Fri Nov 4 17:34:18 2016 Total Scan time: 9.350 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]