FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9599, 439 aa 1>>>pF1KB9599 439 - 439 aa - 439 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5791+/-0.000333; mu= 4.8527+/- 0.021 mean_var=231.4173+/-50.017, 0's: 0 Z-trim(123.9): 142 B-trim: 2200 in 2/55 Lambda= 0.084309 statistics sampled from 44294 (44440) to 44294 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.521), width: 16 Scan time: 8.680 The best scores are: opt bits E(85289) NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 3023 380.1 6.3e-105 NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 2400 304.3 3.9e-82 NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 2370 300.6 4.9e-81 NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 1925 246.5 9.5e-65 NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 756 104.4 7e-22 NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 743 102.8 2e-21 NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 671 94.0 8.8e-19 NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 614 86.9 8e-17 NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 583 83.2 1.2e-15 NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 549 79.1 2e-14 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 523 76.1 2.6e-13 NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 517 75.2 2.9e-13 NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 512 74.7 6e-13 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 487 71.6 4.1e-12 NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 480 70.7 7.3e-12 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 475 70.1 1.1e-11 NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 475 70.1 1.2e-11 NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 461 68.5 4.1e-11 NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 458 68.1 5.4e-11 NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 458 68.1 5.4e-11 NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 451 67.2 8.8e-11 XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 449 67.0 1.1e-10 NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 449 67.0 1.2e-10 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 437 65.5 2.7e-10 NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 414 62.8 2.3e-09 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 394 60.3 1.1e-08 XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 377 58.3 5.8e-08 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 377 58.5 7e-08 NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 353 55.5 4.9e-07 XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 331 52.8 3e-06 XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 328 52.4 3.8e-06 NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 328 52.4 3.9e-06 NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 328 52.4 3.9e-06 XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 328 52.4 3.9e-06 NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 328 52.4 3.9e-06 XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 327 52.3 4.1e-06 XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 324 51.9 5e-06 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 324 51.9 5.1e-06 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 324 51.9 5.2e-06 NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 308 49.8 1.4e-05 XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 299 48.8 3.4e-05 XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 299 48.8 3.4e-05 XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 299 48.8 3.4e-05 XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 299 48.8 3.6e-05 XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 299 48.9 4.6e-05 XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 299 48.9 4.6e-05 XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 299 48.9 4.6e-05 NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 299 48.9 4.6e-05 XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 299 48.9 4.6e-05 XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 299 48.9 4.6e-05 >>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa) initn: 3023 init1: 3023 opt: 3023 Z-score: 2004.8 bits: 380.1 E(85289): 6.3e-105 Smith-Waterman score: 3023; 98.9% identity (99.3% similar) in 439 aa overlap (1-439:1-439) 10 20 30 40 50 60 pF1KB9 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQVARW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQVARW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSL ::::::::::::::: ::::: :::::::::::::::::::::::::::::::::::::: NP_997 PHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGRLLGAPAPPQ :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_997 DPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPAPPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 PVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLV :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 ILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTS 370 380 390 400 410 420 430 pF1KB9 PVFLVSPTPGSLAESAGPS :::::::::.::::::::: NP_997 PVFLVSPTPSSLAESAGPS 430 >>NP_954586 (OMIM: 611086) forkhead box protein D4-like (417 aa) initn: 2197 init1: 2197 opt: 2400 Z-score: 1595.5 bits: 304.3 E(85289): 3.9e-82 Smith-Waterman score: 2402; 87.4% identity (90.1% similar) in 404 aa overlap (1-400:1-395) 10 20 30 40 50 pF1KB9 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDE----EEAASQQFLEQSLQPGLQ :::::::::::::::::::::::::::::::::::::: :::::::::::::::::: NP_954 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMA ::::::::::::::::::::::::::::.::::::::::::::::::::: ::::::::: NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGN :::.::::::::::::::::::::: ::::::::::::::::::::::::::::.::::: NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGRLLGAP ::::::::::::::::::::::::.::: ::::::::::::::::::::::::: ::::: NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 APPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCS ::::::::::::::::::::::::::: ::::::::.::::::::::: ::::::::::: NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 PHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQ ::::::::::::::::::::::::::::: :::::::::::::.::::::::: ::::.: NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRICPRPRGATATCSSDHQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 ACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGG :: : : : : .:: : .:.. : : NP_954 ACCI-----PRPLPLCCK--CPPP--PLLGQFCSNSSSIRRRTAPTAALPPRARCWAGTC 370 380 390 400 410 420 430 pF1KB9 EGTSPVFLVSPTPGSLAESAGPS NP_954 RPRRPC >>NP_954714 (OMIM: 611085) forkhead box protein D4-like (416 aa) initn: 2176 init1: 2176 opt: 2370 Z-score: 1575.8 bits: 300.6 E(85289): 4.9e-81 Smith-Waterman score: 2370; 93.9% identity (95.9% similar) in 362 aa overlap (1-358:1-362) 10 20 30 40 50 pF1KB9 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDE----EEAASQQFLEQSLQPGLQ :::::::: ::::::::::::::::::::::::::::: :: : ::::::::::::: NP_954 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEARQQFLEQSLQPGLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMA ::::::::::::::::::::::::::::.::::::::::::::::::::: ::::::::: NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGN :::.::::::::::::::::::::: ::::::::::::::::::::::::::::.::::: NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGRLLGAP ::::::::::::::::::::::::.::: ::::::::::::::::::::::.:: ::::: NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 APPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCS ::::::::::::::::::::::::::: ::::::: .::::::::::::::::::::::: NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 PHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQ ::::::::::::::::::::::::::::: ::::::::::::::::::::::: ::::.: NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 ACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGG :: NP_954 ACCIPKPLPLCCKCPPPLLLGQFCSNSSSIRRTAPTAALPPRARCWAGTCRPRRRC 370 380 390 400 410 >>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa) initn: 1810 init1: 1503 opt: 1925 Z-score: 1283.4 bits: 246.5 E(85289): 9.5e-65 Smith-Waterman score: 1925; 92.4% identity (94.7% similar) in 303 aa overlap (1-299:1-302) 10 20 30 40 50 pF1KB9 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDE----EEAASQQFLEQSLQPGLQ :::::::: ::::::::::::::::::::::::::::: :: :::.::::::::::: NP_036 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMA :::::::::::::::::: ::::::::::::::::::::::::::::::: ::::::::: NP_036 VARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMA 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGN ::::::::::::::::::::::::: ::::::::::::::::::::::::::::.::::. NP_036 ILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGRLLGAP ::::::::::::::::::::::::.::: ::::::::::::::::::::::::: ::::: NP_036 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 APPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCS : :::::::::::::::::::::::::::::::::::::::::::::::::::. .: . NP_036 ALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQ : : NP_036 PSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS 300 310 320 330 340 350 >>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa) initn: 753 init1: 669 opt: 756 Z-score: 513.9 bits: 104.4 E(85289): 7e-22 Smith-Waterman score: 765; 40.7% identity (53.7% similar) in 447 aa overlap (10-434:42-450) 10 20 30 pF1KB9 MNLPRAERLRSTPQRSLRD--SDGEDGKIDVLGEEEDED :: : :. :: :.. . . :: NP_004 SSESSPAALSEADADIDVVGGGSGGGELPARSGP-RAPRDVLPHGHEPPAEEAEADLAED 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 EEEAASQQFLEQSLQPGLQVARWGGVALP-REHIEGGGGPSDPSEFGTEFRAPPRSAAAS :::... . : . .: .: : .:..::. :. :: ..::. NP_004 EEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPG-PG--------PPSGGAAT 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 EDARQP-AKPPSSYIALITMAILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHN :.: .::: ::::::::::::::.:::::: :: ::::::::: .:::::::::::: NP_004 ---RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHN 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 LSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPF ::::::::::::::: :::::::.::: : :::::::::::::::.: :: : : ::: NP_004 LSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR-QPLPPPH-PHPH 180 190 200 210 220 230 220 230 240 250 260 pF1KB9 PLP-----AAHAALHNPR---PG-RLLGAPAPPQ----PVPGAYPNTAPGRRPYALLHPH : : .. :: .: :: :: . :. :: : :: :. ::: NP_004 PHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPP---PGPAPHP--HPH 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB9 PPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSA : . . .: : : .. . :.: : : : : :. : : : NP_004 PHAFAFAAAAAAAPCQLSVPPGRAAAPPPGP---P--------TASVFAGAGSAPAPAPA 300 310 320 330 340 330 340 350 360 370 pF1KB9 LRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCA---NGCAP : .: : :: : :: :.. : : .: NP_004 ---SGSGPGPGPAGL----PAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKT 350 360 370 380 390 380 390 400 410 420 430 pF1KB9 TKGAVLGGHLSAASALLRYQAV-AEGSGLTSLAAPLGGEGT-SPVFLVSPTPGSLAESAG :. :: ..:. .. : : . : : .:::. .: : .. ::. :. NP_004 DAGGGAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLA 400 410 420 430 440 450 pF1KB9 PS NP_004 MLTAPALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF 460 470 480 490 >>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa) initn: 728 init1: 626 opt: 743 Z-score: 505.7 bits: 102.8 E(85289): 2e-21 Smith-Waterman score: 765; 42.3% identity (58.7% similar) in 421 aa overlap (14-415:53-444) 10 20 30 40 pF1KB9 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAAS .: :. ::: ... : ::::.:. : NP_004 GEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYAGED-ELEDLEEEEDDDDILLAP 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB9 QQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQP- . :: : .:.. :::: . . :. :. :..: NP_004 PAGGSPA-PPGPAPAAGAGAG-------GGGGGGGAGGGGS----------AGSGAKNPL 90 100 110 120 110 120 130 140 150 160 pF1KB9 AKPPSSYIALITMAILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCF .::: ::::::::::::::.:::::: :: ::::::::: .::::::::::::::::::: NP_004 VKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 VKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPT--PGAHLPHPFPLPAA :::::::: :::::::.::: : :::::::::::::::.: :: :.: . . : .: NP_004 VKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR-QPLLPPNAAAAESLLLRGA 190 200 210 220 230 240 230 240 250 260 270 pF1KB9 HAA--LHNPRPGRLLGAPAPPQPVPGAYPNTAPGRRPYAL-LHPHPPRYLLLSAPAYAGA :: .: . : :::: : : :: . .: :.: : :. : :..: : :.: NP_004 GAAGGAGDPAAAAALFPPAPPPP-PHAY-GYGPYGCGYGLQLPPYAPPSALFAAAAAAAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 PKKAEGADLATPAPFPCCSPHLVLS-LGRRARVWRRHREADASLSALRVSC-KGSGERVQ : . .: : : :: . . :.: : .: : . : . : .: :..: .. NP_004 ---AAAFHPHSPPPPP--PPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPGAS 310 320 330 340 350 340 350 360 370 380 pF1KB9 GLRR----VCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANGCAPTKGAVLGG---- .: : . :. .: .. : .. : . : :: :. :: NP_004 ALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAP--GSSGGGCAAQ 360 370 380 390 400 410 390 400 410 420 430 pF1KB9 -HLSAASALLRYQAVAEGSGLTSLA--APLGGEGTSPVFLVSPTPGSLAESAGPS .. :.:: : ..: ... .:.. : :: NP_004 AAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC 420 430 440 450 460 >>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa) initn: 684 init1: 643 opt: 671 Z-score: 458.2 bits: 94.0 E(85289): 8.8e-19 Smith-Waterman score: 680; 39.6% identity (57.6% similar) in 389 aa overlap (61-436:106-460) 40 50 60 70 80 90 pF1KB9 GEEEDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPP :::. .: .::::. : :. : NP_036 QQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVG-GEEGGASGGGPGAGS--GSAGGLAP 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 RSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQN :. . .::: ::::::::::::::.:.::::::: :::.::::: .::::::: NP_036 -----SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQN 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 SIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAH :::::::::::::::::::: :::::::.::: :.:::::::::::::::.::: : NP_036 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQE---H 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 LPHPFPLPAAHAALHNPRPGRLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLS : . : . .. . :: .: : .: .: : : :: NP_036 LREQTALMMQSFGAYSLAAAA--GAAGPYGRPYGLHPAAAAG----AYSHP--------- 250 260 270 280 280 290 300 310 320 pF1KB9 APAYAGAPKKAEGADLATPAPFPCCSPHLVL----SLGRRARVWRRHREADASLSALRVS : : :.: : : : : : . : :::.: .. . .:. :... NP_036 AAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAF--GSQLGPGLQ-LQLN 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB9 CKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANGCAPTKGAVLG :.. . : . :.:: ... . : .. .. : : . . ..: : NP_036 SLGAAAAAAGTAGAA----GTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAG 350 360 370 380 390 400 390 400 410 420 430 pF1KB9 GHL-----SAASALLRYQAVAEGSGLTSLAAPLGGEGTS----PVFLVSPTPGSLAESAG : :.:...:: .......: . ::. :. :.. : : :.. . : NP_036 GTGGSGGGSTAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSV-PLSGQFLQPAA 410 420 430 440 450 460 pF1KB9 PS NP_036 SAAAAAAAAAQAKWPAQ 470 >>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa) initn: 563 init1: 518 opt: 614 Z-score: 423.0 bits: 86.9 E(85289): 8e-17 Smith-Waterman score: 616; 46.4% identity (62.0% similar) in 250 aa overlap (53-296:17-241) 30 40 50 60 70 80 pF1KB9 EDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQ-VARWGGVALPREHIEGGGGPSDPSE :.: :: : : : : : . . NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAA 10 20 30 40 90 100 110 120 130 pF1KB9 FGTEFRAPPRSAAASEDARQP---AKPPSSYIALITMAILQSPHKRLTLSGICAFISGRF : :: . . .. :.: .::: ::::::.::. ..: .::::..: ::. :: NP_036 -GRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB9 PYYCRKFP-AWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRR .: : : :::::::::.:::::::.::::: :::::::.::::. :::::::::::: NP_036 AFY-RDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRR 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB9 KRFQRHQ-PTPGAHLPHPFPLPAAHAALHNPRPGRLLGAPAPPQPVPGAYPNTAPGRRPY :::.: . :. .: : : ::: .: . : :: : .: ::. :: NP_036 KRFKRAELPAHAAAAPGP-PLPFPYAP-YAPAPGPALLVP-PPSAGPG------------ 170 180 190 200 260 270 280 290 300 310 pF1KB9 ALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREA : :: :. :. . .. . : : :..: : :::. NP_036 ----PSPPARLF-SVDSLVNL--QPELAGLGAPEP-PCCAAPDAAAAAFPPCAAAASPPL 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB9 DASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANG NP_036 YSQVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL 270 280 290 300 310 >>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa) initn: 543 init1: 518 opt: 583 Z-score: 401.7 bits: 83.2 E(85289): 1.2e-15 Smith-Waterman score: 583; 47.2% identity (66.2% similar) in 216 aa overlap (83-291:30-240) 60 70 80 90 100 110 pF1KB9 PGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDAR--QPAKPPSSYI :. .: :.:.. . : : .::: ::: NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYI 10 20 30 40 50 120 130 140 150 160 170 pF1KB9 ALITMAILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIRHNLSLNDCFVKIPREPG :::.::: ..:..::::.:: ::. :::.: . :::::::::.:::::.::::: : NP_004 ALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAG 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB9 RPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPG ::::::::.::: ..:::..::::::::::.: . . : :: :: . NP_004 RPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAA 120 130 140 150 160 170 240 250 260 270 280 pF1KB9 RLLGA-PAPPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPA----YAGAPKKAEGAD . :: :: : ::: . : : .: : :: : ..:. .. .:.. . . NP_004 IFPGAVPAARPPYPGA---VYAGYAPPSLAAP-PPVYYPAASPGPCRVFGLVPERPLSPE 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB9 LATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPR :. ::: NP_004 LG-PAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGS 240 250 260 270 280 290 >>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa) initn: 635 init1: 501 opt: 549 Z-score: 379.8 bits: 79.1 E(85289): 2e-14 Smith-Waterman score: 568; 38.1% identity (54.8% similar) in 341 aa overlap (64-397:14-305) 40 50 60 70 80 90 pF1KB9 EDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSA : : .. : :. : : :: . NP_005 MSHLFDPRLPALAASPMLYLYGPERPGLPLAF-----APAAAL 10 20 30 100 110 120 130 140 150 pF1KB9 AASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISGRFPYYCRKFPAWQNSIR ::: :. : ::: ::::::.::: ..:..:.::.:: :: :::.: . .:::::: NP_005 AASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 HNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGA-HLP :::::::::::.::: ::::::.::.::: :::.::.. ::::: . .: ::: . NP_005 HNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 HPFPLPAAHAALHNPRPGRLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAP .: ..: .:. : :. .: : : : : : : :: : : NP_005 RPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAP---AGPSPL-LDGPSPPAP--LHWP 160 170 180 190 200 280 290 300 310 320 330 pF1KB9 AYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGE . : .:.. : : : : ....:. ::. .:. : :: NP_005 GTA-SPNEDAG-DAAQGAA--------AVAVGQAART------GDGPGSPLR-------- 210 220 230 240 340 350 360 370 380 pF1KB9 RVQGLRRVCPRPRGATAPCSSDRQACRTI------LQQQQRHQEEDCANGCAPTKGAVLG : . ..: :::.. .: : :. . .. .: : :. :: NP_005 -----------PASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLG 250 260 270 280 290 390 400 410 420 430 pF1KB9 GHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPGSLAESAGPS . : :::. :: NP_005 ASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ 300 310 320 330 340 439 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:36:09 2016 done: Fri Nov 4 17:36:11 2016 Total Scan time: 8.680 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]