FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9603, 345 aa 1>>>pF1KB9603 345 - 345 aa - 345 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3193+/-0.00089; mu= -4.7374+/- 0.054 mean_var=302.7210+/-61.202, 0's: 0 Z-trim(116.9): 67 B-trim: 0 in 0/50 Lambda= 0.073715 statistics sampled from 17475 (17542) to 17475 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.539), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS10959.1 FOXL1 gene_id:2300|Hs108|chr16 ( 345) 2394 267.3 1.4e-71 CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 ( 553) 637 80.6 3.4e-15 CCDS3105.1 FOXL2 gene_id:668|Hs108|chr3 ( 376) 607 77.3 2.3e-14 CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 ( 501) 606 77.3 3.1e-14 CCDS35078.1 FOXE1 gene_id:2304|Hs108|chr9 ( 373) 593 75.8 6.5e-14 CCDS2117.1 FOXD4L1 gene_id:200350|Hs108|chr2 ( 408) 569 73.2 4.1e-13 CCDS34975.1 FOXD4 gene_id:2298|Hs108|chr9 ( 439) 566 73.0 5.4e-13 CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 ( 330) 556 71.8 9.1e-13 CCDS4372.1 FOXI1 gene_id:2299|Hs108|chr5 ( 378) 552 71.4 1.4e-12 CCDS75259.1 FOXD1 gene_id:2297|Hs108|chr5 ( 465) 546 70.8 2.5e-12 CCDS30708.1 FOXD2 gene_id:2306|Hs108|chr1 ( 495) 546 70.9 2.6e-12 CCDS43833.1 FOXD4L3 gene_id:286380|Hs108|chr9 ( 417) 544 70.6 2.6e-12 CCDS43826.1 FOXD4L6 gene_id:653404|Hs108|chr9 ( 417) 544 70.6 2.6e-12 CCDS47977.1 FOXD4L5 gene_id:653427|Hs108|chr9 ( 416) 539 70.1 3.8e-12 CCDS75845.1 FOXD4L4 gene_id:349334|Hs108|chr9 ( 416) 539 70.1 3.8e-12 CCDS77433.1 FOXI3 gene_id:344167|Hs108|chr2 ( 420) 539 70.1 3.8e-12 CCDS550.1 FOXE3 gene_id:2301|Hs108|chr1 ( 319) 516 67.5 1.7e-11 CCDS35045.1 FOXB2 gene_id:442425|Hs108|chr9 ( 432) 516 67.6 2.1e-11 CCDS10957.2 FOXF1 gene_id:2294|Hs108|chr16 ( 379) 513 67.3 2.4e-11 CCDS9665.1 FOXA1 gene_id:3169|Hs108|chr14 ( 472) 515 67.6 2.4e-11 CCDS7655.2 FOXI2 gene_id:399823|Hs108|chr10 ( 318) 508 66.7 3e-11 CCDS32255.1 FOXB1 gene_id:27023|Hs108|chr15 ( 325) 506 66.5 3.6e-11 CCDS624.1 FOXD3 gene_id:27022|Hs108|chr1 ( 478) 508 66.8 4.1e-11 CCDS13147.1 FOXA2 gene_id:3170|Hs108|chr20 ( 457) 504 66.4 5.4e-11 CCDS46585.1 FOXA2 gene_id:3170|Hs108|chr20 ( 463) 504 66.4 5.4e-11 >>CCDS10959.1 FOXL1 gene_id:2300|Hs108|chr16 (345 aa) initn: 2394 init1: 2394 opt: 2394 Z-score: 1398.8 bits: 267.3 E(32554): 1.4e-71 Smith-Waterman score: 2394; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 GSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAA 250 260 270 280 290 300 310 320 330 340 pF1KB9 SSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ ::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ 310 320 330 340 >>CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 (553 aa) initn: 632 init1: 562 opt: 637 Z-score: 386.2 bits: 80.6 E(32554): 3.4e-15 Smith-Waterman score: 671; 42.6% identity (64.4% similar) in 298 aa overlap (49-319:78-367) 20 30 40 50 60 70 pF1KB9 YLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQF ::::::::::.::::.::....:::::::: CCDS44 SHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQF 50 60 70 80 90 100 80 90 100 110 120 130 pF1KB9 IMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNY ::::::::.::.::::::::::::::.:::::::. .::::::::::: .:::::.. CCDS44 IMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSF 110 120 130 140 150 160 140 150 160 170 180 pF1KB9 RRRKRKPKPGPGAPEAKRPRAETH--------QRSAEAQPEAGSG-AGGSGPAISRLQ-- ::.:. : : . :. . . : .. : :: ..: : : : :.: CCDS44 LRRRRRFKK-KDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDI 170 180 190 200 210 220 190 200 210 220 230 pF1KB9 -----AAPAGPSPLLDGPSPPAPLH------WPGTASPNEDAGDAAQGAAAVAVGQAAR- . :. :.:: :: : : : ::. .... ..:.. . .:: CCDS44 KTENGTCPSPPQPL----SPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARP 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB9 -TGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGG--AKPGPGGR . :: : : . :.: .:..::.:.:... .:. .. :: .: :. . ..: CCDS44 LSLDGADSAPPPPAPSAPPPH-HSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSR 290 300 310 320 330 340 300 310 320 330 340 pF1KB9 LG-ASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ : : :: .. : ..::. .: : CCDS44 AGIAPPLALGA--YSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQA 350 360 370 380 390 >>CCDS3105.1 FOXL2 gene_id:668|Hs108|chr3 (376 aa) initn: 681 init1: 557 opt: 607 Z-score: 371.2 bits: 77.3 E(32554): 2.3e-14 Smith-Waterman score: 612; 38.8% identity (58.7% similar) in 312 aa overlap (22-316:29-319) 10 20 30 40 50 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYS :: : : . ... .: . . :::::: CCDS31 MMASYPEPEDAAGALLAPETGRTVKEPEGP--PPSPGKGGGGGGGTAPEKPDPAQKPPYS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 YIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE :.:::::::... :.:.::.::::.:. .::::. :..:::::::::::::.::.::::: CCDS31 YVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPRE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 KGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAG : ::.:::::: : ::::.::::::.: .: :: .: . ... :: CCDS31 GGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPF-------RP-PPAHFQPGKGLFGAG 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLH-------WPGTASPNEDAGDAAQGAA ..::: : : :. : . : .:: :. :: :. . : :: CCDS31 GAAGGCGVA----GAGADGYGYL----APPKYLQSGFLNNSWPLPQPPSPMPYASCQMAA 180 190 200 210 220 230 240 250 260 270 pF1KB9 AVAVGQAARTGDGPGSP---------LRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPS :.:.. :: .. ::::: ::. .: . .: .. . . . ::. CCDS31 AAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB9 GDELLGGAKPGPGGR-LGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQ . .: : .. : : ::. :: ... : CCDS31 APPPPPHPHPHPHAHHLHA---AAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTS 290 300 310 320 330 340 pF1KB9 VPDTVLHFQ CCDS31 APGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL 340 350 360 370 >>CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 (501 aa) initn: 606 init1: 560 opt: 606 Z-score: 369.0 bits: 77.3 E(32554): 3.1e-14 Smith-Waterman score: 644; 41.7% identity (61.0% similar) in 336 aa overlap (14-333:35-339) 10 20 30 40 pF1KB9 MSHLFDPRLPALAASPM-LYLYGPER--PGLPLAFAPAAALAA :::: .: ::. :. ..:: CCDS10 YSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 SGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHN .. . ::::::::::.::::.:::...::::::::::::::::..:.:::::::::: CCDS10 AAPKDLV-KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAE ::::.:::::::. .::::::::::: .:::::.. ::.:. : . : :. :: CCDS10 LSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKE-KEERA- 130 140 150 160 170 180 170 180 190 200 210 pF1KB9 THQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLL----DGPSPPAP-LHWPGTASPN : . : : :..:: :: .: :: . .. :: : . : ::. CCDS10 -HLK--EPPPAASKGA----PATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPE 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 EDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKP .: ::. :.. : . :: . : . :. .:.. .::...:.. . .: CCDS10 ----SALQGSPRSAASTPAGSPDG-SLPEHHAA--APNGL---PGFSVENIMTLRT--SP 240 250 260 270 280 280 290 300 310 320 pF1KB9 PSGDELLGGAKPGPGGRLGASL--LAASSSLRPPFNASLMLDPHVQG------GFYQLGI :.: :: :: :: : . :: . :: . . .: .:: : :: .. CCDS10 PGG-ELSPGA-----GRAGLVVPPLALPYAAAPP---AAYGQPCAQGLEAGAAGGYQCSM 290 300 310 320 330 330 340 pF1KB9 PFLSYFPLQVPDTVLHFQ .: . CCDS10 RAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHG 340 350 360 370 380 390 >>CCDS35078.1 FOXE1 gene_id:2304|Hs108|chr9 (373 aa) initn: 625 init1: 515 opt: 593 Z-score: 363.2 bits: 75.8 E(32554): 6.5e-14 Smith-Waterman score: 599; 39.5% identity (61.1% similar) in 296 aa overlap (27-307:30-306) 10 20 30 40 50 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRA-ETPQ---KPPYS :.: . :.. .:.:: . : ::::: CCDS35 MTAESGPPPPQPEVLATVKEERGETAAGAGVP---GEATGRGAGGRRRKRPLQRGKPPYS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 YIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE ::::::::: :::.:.::.:::.:: .:::::.:: . :::::::::.:::::.:.::: CCDS35 YIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPRE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 KGRPGKGSYWTLDPRCLDMFENGNY-RRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEA ::::::.::.::: ::::.:.. ::::: . .. : : . .: : : CCDS35 AGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAA 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 GSGAGGSGPAISRLQAAPAGPSPLLDGPSPPA-----PLHWPGTA-SPNEDAGDAAQGAA .. :. :: : : :. . : .::. :...:... .: . : . . CCDS35 AAIFPGAVPA-----ARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 AVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAK . .: : .:::. :: ..: .. . :: : .: . . ..: CCDS35 SPELGPAP---SGPGGSCAFASAGAPATTTGYQP-------AGCTGARPANPSAY-AAAY 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 PGPGGRL----GASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVL :: : :....::.. : : CCDS35 AGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYN 290 300 310 320 330 340 >>CCDS2117.1 FOXD4L1 gene_id:200350|Hs108|chr2 (408 aa) initn: 540 init1: 510 opt: 569 Z-score: 348.9 bits: 73.2 E(32554): 4.1e-13 Smith-Waterman score: 569; 40.5% identity (57.2% similar) in 306 aa overlap (22-311:78-368) 10 20 30 40 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPG-LPLAF-APAAALAASGRAETPQK :: :. . : :: . ::: :. : : CCDS21 QKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAK 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB9 PPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVK :::::::::.::: ..:..:.::.:: :: :::.:. . .::::::::::::::::: CCDS21 PPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVK 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB9 VPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAKRPRAETHQRSA .::: :.::::.::.::: :::.::.. ::::: . . ::: . .: ..: CCDS21 IPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGA-HLPHPFPLPAAHAA 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB9 EAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAA .:. : :. ::. : .:.. : : : :: : .. : :: CCDS21 LHNPRPGPLLGA--PALP--QPVPGAYPNTAPGRRPYALLH-PHPPRYLLLSAPAYAGAP 230 240 250 260 270 280 230 240 250 260 270 pF1KB9 AVAVGQAARTGDGPGS-P-LRPASRSSPKSSDKSK---------SFSIDSILAGKQGQKP : : : ::. : :.:. .: :. ::::.::. : .: CCDS21 KKAEGADLAT---PGTLPVLQPSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGT 290 300 310 320 330 280 290 300 310 320 330 pF1KB9 PSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPL ... : .: . :: ::: : :. CCDS21 GAAQSL------SPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAP 340 350 360 370 380 390 340 pF1KB9 QVPDTVLHFQ CCDS21 VGRVGAAAVSGGGRGL 400 >>CCDS34975.1 FOXD4 gene_id:2298|Hs108|chr9 (439 aa) initn: 656 init1: 513 opt: 566 Z-score: 346.8 bits: 73.0 E(32554): 5.4e-13 Smith-Waterman score: 585; 39.1% identity (56.8% similar) in 338 aa overlap (14-305:64-397) 10 20 30 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAF-----APAAAL : : .. : :. : : :: . CCDS34 EDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSA 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB9 AASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIR ::: :. : ::: ::::::.::: ..:..:.::.:: :: ::::.:. . .:::::: CCDS34 AASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIR 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB9 HNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAK :::::::::::.::: ::::::.::.::: :::.::.. ::::: . .: ::: . CCDS34 HNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGA-HLP 160 170 180 190 200 210 160 170 180 190 200 pF1KB9 RPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAP-AGPS--PL-LDGPSPPAPL--HWP .: ..: .:. : :. .: : : .::. : : : :: : : CCDS34 HPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAP 220 230 240 250 260 270 210 220 230 240 250 pF1KB9 GTA-SPNEDAG-DAAQGAA--------AVAVGQAART------GDGPGSPLRPASRSS-- . : .:.. : : : : ....:. ::. .:. : :: . ..: CCDS34 AYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGE 280 290 300 310 320 330 260 270 280 290 pF1KB9 ---------PKSSDKSKSFSID-----SILAGKQGQKPPSGDELLGGAKPGPGGRLGASL :. . : : .:: : :. . .. .: : :. ::. : CCDS34 RVQGLRRVCPRPRGATAPCSSDRQACRTIL---QQQQRHQEEDCANGCAPTKGAVLGGHL 340 350 360 370 380 300 310 320 330 340 pF1KB9 LAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ :::. :: CCDS34 SAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS 390 400 410 420 430 >>CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 (330 aa) initn: 559 init1: 538 opt: 556 Z-score: 342.7 bits: 71.8 E(32554): 9.1e-13 Smith-Waterman score: 601; 41.0% identity (58.7% similar) in 317 aa overlap (47-334:16-324) 20 30 40 50 60 70 pF1KB9 MLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIY : :::::::::::::::..: ::.::.::: CCDS13 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIY 10 20 30 40 80 90 100 110 120 130 pF1KB9 QFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENG ..:: :: ::. :: :::::::::::::.:::::::. .::::::::::: : ::::.: CCDS13 RYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHG 50 60 70 80 90 100 140 150 160 170 180 pF1KB9 NYRRRKRKPKPGPGAPEAKRP-RAETHQRSAEAQ----PEAGSGAGGSGP-------AIS .. ::.:. :: .. : .:. : .: :.: .: : : ..: CCDS13 SFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLS 110 120 130 140 150 160 190 200 210 220 230 pF1KB9 R---LQAAPAGPSP-LLDG-PSPPA-P--LHWPGTASPNEDAGDAAQGAAAVAVGQAART . : ::. : :: : :: : . : : :.: :..... : : : CCDS13 FGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGE-LPVATSSSSCPAFGFPAGF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB9 GDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGAS ... . :. ::.:. :. . : .: : . ..::..: :.:. CCDS13 SEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADP-GLEHLLASAAPSPAPP---- 230 240 250 260 270 300 310 320 330 340 pF1KB9 LLAASSSLRPPFN-ASLMLDPHVQGGF-------YQLGI-PFLSYFPLQVPDTVLHFQ . .::: :. . .: : ::: : ::. : : : CCDS13 --TPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE 280 290 300 310 320 330 >>CCDS4372.1 FOXI1 gene_id:2299|Hs108|chr5 (378 aa) initn: 555 init1: 493 opt: 552 Z-score: 339.6 bits: 71.4 E(32554): 1.4e-12 Smith-Waterman score: 566; 38.0% identity (58.0% similar) in 324 aa overlap (7-312:74-364) 10 20 30 pF1KB9 MSHLFDPRLPALAASPML-YLYGPERPGLP----LA : ::. :::.: :: .:: :: :. CCDS43 PQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLG 50 60 70 80 90 100 40 50 60 70 80 pF1KB9 FAPAAALAASGRAETPQ--KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDN . . : .. : . .::::: :::::::. ::..:.::. :::.. : ::::. . CCDS43 GSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKS 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB9 RQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGP . :::::::::::::::: ::::.. ::::.:::::: : ::.:::.::.. CCDS43 KAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR------- 170 180 190 200 210 150 160 170 180 190 200 pF1KB9 GAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWP :: . . .. : .. :. ..: .. :. .::: :: . : CCDS43 -----KRKSDVSSSTASLALEKTESSLPVDSPKTTE-------PQDILDGASPGGTTSSP 220 230 240 250 260 210 220 230 240 250 260 pF1KB9 GTASPNEDAGDAAQGAAAVAVGQAARTGDGPGS-PL-RPASRSSPKSSDKS-------KS :. . : . .. : .: .: : :: :. ::. :::. .: CCDS43 -EKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGL--SPEPSDKTGQNSLTFNS 270 280 290 300 310 320 270 280 290 300 310 pF1KB9 FSIDSILAGKQGQKPPSGDELLGGAKPGPGGRL--GASLLAASSSLRPPFNASLMLDPHV :: . :....: .:: :.: : . : :.:.: :.. : : :. CCDS43 FSPLTNLSNHSG----GGD----WANPMPTNMLSYGGSVL---SQFSPHFYNSVNTSGVL 330 340 350 360 370 320 330 340 pF1KB9 QGGFYQLGIPFLSYFPLQVPDTVLHFQ CCDS43 YPREGTEV >>CCDS75259.1 FOXD1 gene_id:2297|Hs108|chr5 (465 aa) initn: 531 init1: 492 opt: 546 Z-score: 334.9 bits: 70.8 E(32554): 2.5e-12 Smith-Waterman score: 562; 40.7% identity (59.0% similar) in 317 aa overlap (39-306:115-418) 10 20 30 40 50 60 pF1KB9 LPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQ-KPPYSYIALIAMAIQDAPE :.:: :..: ::::::::::.::: ..:. CCDS75 GSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSG-AKNPLVKPPYSYIALITMAILQSPK 90 100 110 120 130 140 70 80 90 100 110 120 pF1KB9 QRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDP .:.::. : .:: :::.:... .:::::::::::::::::.::: : ::::.:::::: CCDS75 KRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDP 150 160 170 180 190 200 130 140 150 160 170 180 pF1KB9 RCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGA-GGSG-PAISR . :::.::.. ::... : : : : : .::. :.:: ::.: :: . CCDS75 ESADMFDNGSFLRRRKRFKRQPLLP----PNAA----AAESLLLRGAGAAGGAGDPAAAA 210 220 230 240 250 190 200 210 220 230 pF1KB9 LQAAPAGPSP-LLDGPSPPA---PLHWPGTASPNEDAGDAAQGAAAVAV----------- :: : : : .: . :. : : :. . :: .:::.: CCDS75 ALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSALFAAAAAAAAAAAFHPHSPPPPPPP 260 270 280 290 300 310 240 250 260 270 pF1KB9 -GQAA---RTGDG----------PGS-PLRPASRSSPKSSDKSKS-FSIDSILAGKQG-- : :: ::. : :: : :. ..: .: ..: :::.::..:. : CCDS75 HGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPGASALARSPFSIESIIGGSLGPA 320 330 340 350 360 370 280 290 300 310 pF1KB9 -------------QKPPSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQ : :: . . .: :.::. :. ::.... : CCDS75 AAAAAAAQAAAAAQASPSPSPV--AAPPAPGSSGGGC--AAQAAVGPAAALTRSLVAAAA 380 390 400 410 420 430 320 330 340 pF1KB9 GGFYQLGIPFLSYFPLQVPDTVLHFQ CCDS75 AAASSVSSSAALGTLHQGTALSSVENFTARISNC 440 450 460 345 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:37:57 2016 done: Fri Nov 4 17:37:58 2016 Total Scan time: 2.800 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]