FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9603, 345 aa 1>>>pF1KB9603 345 - 345 aa - 345 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0830+/-0.000354; mu= -9.2147+/- 0.022 mean_var=331.0610+/-67.400, 0's: 0 Z-trim(124.2): 134 B-trim: 0 in 0/59 Lambda= 0.070489 statistics sampled from 45196 (45332) to 45196 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.532), width: 16 Scan time: 8.940 The best scores are: opt bits E(85289) NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 2394 256.4 6.6e-68 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 637 77.9 5.8e-14 NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 607 74.7 3.6e-13 NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 606 74.7 4.8e-13 NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 593 73.3 9.5e-13 NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 569 70.9 5.6e-12 NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 566 70.6 7.3e-12 NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 556 69.5 1.2e-11 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 552 69.1 1.7e-11 NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 546 68.6 3.1e-11 NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 546 68.6 3.3e-11 NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 544 68.3 3.3e-11 NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 539 67.8 4.7e-11 NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 539 67.8 4.7e-11 NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 516 65.4 1.9e-10 XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 515 65.4 2.6e-10 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 513 65.2 2.7e-10 NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 515 65.4 2.8e-10 NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 508 64.7 4.6e-10 NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 504 64.3 5.9e-10 NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 504 64.3 6e-10 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 480 61.8 2.6e-09 NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 477 61.5 3.9e-09 NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 457 59.5 1.7e-08 NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 435 57.2 7e-08 NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 426 56.5 1.9e-07 NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 384 51.9 1.9e-06 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 381 51.8 3.2e-06 XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 373 51.0 7.2e-06 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 373 51.1 8.8e-06 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 361 49.8 1.7e-05 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 361 49.8 1.7e-05 XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 361 49.8 1.7e-05 XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 361 49.8 1.8e-05 NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 361 49.9 1.8e-05 NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 361 49.9 1.8e-05 NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 361 49.9 1.8e-05 XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 361 49.9 1.8e-05 XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 361 49.9 1.8e-05 XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 349 48.5 3.2e-05 XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 349 48.5 3.2e-05 XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 349 48.5 3.2e-05 XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 349 48.5 3.3e-05 XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 349 48.6 4.3e-05 XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 349 48.6 4.3e-05 XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 349 48.6 4.3e-05 NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 349 48.6 4.3e-05 XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 349 48.6 4.3e-05 XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 349 48.6 4.3e-05 NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 339 47.5 6.8e-05 >>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa) initn: 2394 init1: 2394 opt: 2394 Z-score: 1340.1 bits: 256.4 E(85289): 6.6e-68 Smith-Waterman score: 2394; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 GSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAA 250 260 270 280 290 300 310 320 330 340 pF1KB9 SSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ ::::::::::::::::::::::::::::::::::::::::::::: NP_005 SSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ 310 320 330 340 >>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa) initn: 632 init1: 562 opt: 637 Z-score: 371.6 bits: 77.9 E(85289): 5.8e-14 Smith-Waterman score: 671; 42.6% identity (64.4% similar) in 298 aa overlap (49-319:78-367) 20 30 40 50 60 70 pF1KB9 YLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQF ::::::::::.::::.::....:::::::: NP_001 SHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQF 50 60 70 80 90 100 80 90 100 110 120 130 pF1KB9 IMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNY ::::::::.::.::::::::::::::.:::::::. .::::::::::: .:::::.. NP_001 IMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSF 110 120 130 140 150 160 140 150 160 170 180 pF1KB9 RRRKRKPKPGPGAPEAKRPRAETH--------QRSAEAQPEAGSG-AGGSGPAISRLQ-- ::.:. : : . :. . . : .. : :: ..: : : : :.: NP_001 LRRRRRFKK-KDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDI 170 180 190 200 210 220 190 200 210 220 230 pF1KB9 -----AAPAGPSPLLDGPSPPAPLH------WPGTASPNEDAGDAAQGAAAVAVGQAAR- . :. :.:: :: : : : ::. .... ..:.. . .:: NP_001 KTENGTCPSPPQPL----SPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARP 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB9 -TGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGG--AKPGPGGR . :: : : . :.: .:..::.:.:... .:. .. :: .: :. . ..: NP_001 LSLDGADSAPPPPAPSAPPPH-HSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSR 290 300 310 320 330 340 300 310 320 330 340 pF1KB9 LG-ASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ : : :: .. : ..::. .: : NP_001 AGIAPPLALGA--YSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQA 350 360 370 380 390 >>NP_075555 (OMIM: 110100,605597,608996) forkhead box pr (376 aa) initn: 681 init1: 557 opt: 607 Z-score: 357.5 bits: 74.7 E(85289): 3.6e-13 Smith-Waterman score: 612; 38.8% identity (58.7% similar) in 312 aa overlap (22-316:29-319) 10 20 30 40 50 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYS :: : : . ... .: . . :::::: NP_075 MMASYPEPEDAAGALLAPETGRTVKEPEGP--PPSPGKGGGGGGGTAPEKPDPAQKPPYS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 YIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE :.:::::::... :.:.::.::::.:. .::::. :..:::::::::::::.::.::::: NP_075 YVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPRE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 KGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAG : ::.:::::: : ::::.::::::.: .: :: .: . ... :: NP_075 GGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPF-------RP-PPAHFQPGKGLFGAG 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLH-------WPGTASPNEDAGDAAQGAA ..::: : : :. : . : .:: :. :: :. . : :: NP_075 GAAGGCGVA----GAGADGYGYL----APPKYLQSGFLNNSWPLPQPPSPMPYASCQMAA 180 190 200 210 220 230 240 250 260 270 pF1KB9 AVAVGQAARTGDGPGSP---------LRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPS :.:.. :: .. ::::: ::. .: . .: .. . . . ::. NP_075 AAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB9 GDELLGGAKPGPGGR-LGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQ . .: : .. : : ::. :: ... : NP_075 APPPPPHPHPHPHAHHLHA---AAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTS 290 300 310 320 330 340 pF1KB9 VPDTVLHFQ NP_075 APGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL 340 350 360 370 >>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa) initn: 606 init1: 560 opt: 606 Z-score: 355.2 bits: 74.7 E(85289): 4.8e-13 Smith-Waterman score: 644; 41.7% identity (61.0% similar) in 336 aa overlap (14-333:35-339) 10 20 30 40 pF1KB9 MSHLFDPRLPALAASPM-LYLYGPER--PGLPLAFAPAAALAA :::: .: ::. :. ..:: NP_005 YSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 SGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHN .. . ::::::::::.::::.:::...::::::::::::::::..:.:::::::::: NP_005 AAPKDLV-KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAE ::::.:::::::. .::::::::::: .:::::.. ::.:. : . : :. :: NP_005 LSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKE-KEERA- 130 140 150 160 170 180 170 180 190 200 210 pF1KB9 THQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLL----DGPSPPAP-LHWPGTASPN : . : : :..:: :: .: :: . .. :: : . : ::. NP_005 -HLK--EPPPAASKGA----PATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPE 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 EDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKP .: ::. :.. : . :: . : . :. .:.. .::...:.. . .: NP_005 ----SALQGSPRSAASTPAGSPDG-SLPEHHAA--APNGL---PGFSVENIMTLRT--SP 240 250 260 270 280 280 290 300 310 320 pF1KB9 PSGDELLGGAKPGPGGRLGASL--LAASSSLRPPFNASLMLDPHVQG------GFYQLGI :.: :: :: :: : . :: . :: . . .: .:: : :: .. NP_005 PGG-ELSPGA-----GRAGLVVPPLALPYAAAPP---AAYGQPCAQGLEAGAAGGYQCSM 290 300 310 320 330 330 340 pF1KB9 PFLSYFPLQVPDTVLHFQ .: . NP_005 RAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHG 340 350 360 370 380 390 >>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa) initn: 625 init1: 515 opt: 593 Z-score: 349.8 bits: 73.3 E(85289): 9.5e-13 Smith-Waterman score: 599; 39.5% identity (61.1% similar) in 296 aa overlap (27-307:30-306) 10 20 30 40 50 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRA-ETPQ---KPPYS :.: . :.. .:.:: . : ::::: NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVP---GEATGRGAGGRRRKRPLQRGKPPYS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 YIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE ::::::::: :::.:.::.:::.:: .:::::.:: . :::::::::.:::::.:.::: NP_004 YIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPRE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 KGRPGKGSYWTLDPRCLDMFENGNY-RRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEA ::::::.::.::: ::::.:.. ::::: . .. : : . .: : : NP_004 AGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAA 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 GSGAGGSGPAISRLQAAPAGPSPLLDGPSPPA-----PLHWPGTA-SPNEDAGDAAQGAA .. :. :: : : :. . : .::. :...:... .: . : . . NP_004 AAIFPGAVPA-----ARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 AVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAK . .: : .:::. :: ..: .. . :: : .: . . ..: NP_004 SPELGPAP---SGPGGSCAFASAGAPATTTGYQP-------AGCTGARPANPSAY-AAAY 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 PGPGGRL----GASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVL :: : :....::.. : : NP_004 AGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYN 290 300 310 320 330 340 >>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa) initn: 540 init1: 510 opt: 569 Z-score: 336.1 bits: 70.9 E(85289): 5.6e-12 Smith-Waterman score: 569; 40.5% identity (57.2% similar) in 306 aa overlap (22-311:78-368) 10 20 30 40 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPG-LPLAF-APAAALAASGRAETPQK :: :. . : :: . ::: :. : : NP_036 QKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAK 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB9 PPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVK :::::::::.::: ..:..:.::.:: :: :::.:. . .::::::::::::::::: NP_036 PPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVK 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB9 VPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAKRPRAETHQRSA .::: :.::::.::.::: :::.::.. ::::: . . ::: . .: ..: NP_036 IPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGA-HLPHPFPLPAAHAA 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB9 EAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAA .:. : :. ::. : .:.. : : : :: : .. : :: NP_036 LHNPRPGPLLGA--PALP--QPVPGAYPNTAPGRRPYALLH-PHPPRYLLLSAPAYAGAP 230 240 250 260 270 280 230 240 250 260 270 pF1KB9 AVAVGQAARTGDGPGS-P-LRPASRSSPKSSDKSK---------SFSIDSILAGKQGQKP : : : ::. : :.:. .: :. ::::.::. : .: NP_036 KKAEGADLAT---PGTLPVLQPSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGT 290 300 310 320 330 280 290 300 310 320 330 pF1KB9 PSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPL ... : .: . :: ::: : :. NP_036 GAAQSL------SPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAP 340 350 360 370 380 390 340 pF1KB9 QVPDTVLHFQ NP_036 VGRVGAAAVSGGGRGL 400 >>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa) initn: 656 init1: 513 opt: 566 Z-score: 334.0 bits: 70.6 E(85289): 7.3e-12 Smith-Waterman score: 585; 39.1% identity (56.8% similar) in 338 aa overlap (14-305:64-397) 10 20 30 pF1KB9 MSHLFDPRLPALAASPMLYLYGPERPGLPLAF-----APAAAL : : .. : :. : : :: . NP_997 EDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSA 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB9 AASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIR ::: :. : ::: ::::::.::: ..:..:.::.:: :: ::::.:. . .:::::: NP_997 AASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIR 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB9 HNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAK :::::::::::.::: ::::::.::.::: :::.::.. ::::: . .: ::: . NP_997 HNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGA-HLP 160 170 180 190 200 210 160 170 180 190 200 pF1KB9 RPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAP-AGPS--PL-LDGPSPPAPL--HWP .: ..: .:. : :. .: : : .::. : : : :: : : NP_997 HPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAP 220 230 240 250 260 270 210 220 230 240 250 pF1KB9 GTA-SPNEDAG-DAAQGAA--------AVAVGQAART------GDGPGSPLRPASRSS-- . : .:.. : : : : ....:. ::. .:. : :: . ..: NP_997 AYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGE 280 290 300 310 320 330 260 270 280 290 pF1KB9 ---------PKSSDKSKSFSID-----SILAGKQGQKPPSGDELLGGAKPGPGGRLGASL :. . : : .:: : :. . .. .: : :. ::. : NP_997 RVQGLRRVCPRPRGATAPCSSDRQACRTIL---QQQQRHQEEDCANGCAPTKGAVLGGHL 340 350 360 370 380 300 310 320 330 340 pF1KB9 LAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ :::. :: NP_997 SAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS 390 400 410 420 430 >>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa) initn: 559 init1: 538 opt: 556 Z-score: 330.2 bits: 69.5 E(85289): 1.2e-11 Smith-Waterman score: 601; 41.0% identity (58.7% similar) in 317 aa overlap (47-334:16-324) 20 30 40 50 60 70 pF1KB9 MLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIY : :::::::::::::::..: ::.::.::: NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIY 10 20 30 40 80 90 100 110 120 130 pF1KB9 QFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENG ..:: :: ::. :: :::::::::::::.:::::::. .::::::::::: : ::::.: NP_004 RYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHG 50 60 70 80 90 100 140 150 160 170 180 pF1KB9 NYRRRKRKPKPGPGAPEAKRP-RAETHQRSAEAQ----PEAGSGAGGSGP-------AIS .. ::.:. :: .. : .:. : .: :.: .: : : ..: NP_004 SFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLS 110 120 130 140 150 160 190 200 210 220 230 pF1KB9 R---LQAAPAGPSP-LLDG-PSPPA-P--LHWPGTASPNEDAGDAAQGAAAVAVGQAART . : ::. : :: : :: : . : : :.: :..... : : : NP_004 FGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGE-LPVATSSSSCPAFGFPAGF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB9 GDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGAS ... . :. ::.:. :. . : .: : . ..::..: :.:. NP_004 SEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADP-GLEHLLASAAPSPAPP---- 230 240 250 260 270 300 310 320 330 340 pF1KB9 LLAASSSLRPPFN-ASLMLDPHVQGGF-------YQLGI-PFLSYFPLQVPDTVLHFQ . .::: :. . .: : ::: : ::. : : : NP_004 --TPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE 280 290 300 310 320 330 >>NP_036320 (OMIM: 274600,600791,601093) forkhead box pr (378 aa) initn: 555 init1: 493 opt: 552 Z-score: 327.2 bits: 69.1 E(85289): 1.7e-11 Smith-Waterman score: 566; 38.0% identity (58.0% similar) in 324 aa overlap (7-312:74-364) 10 20 30 pF1KB9 MSHLFDPRLPALAASPML-YLYGPERPGLP----LA : ::. :::.: :: .:: :: :. NP_036 PQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLG 50 60 70 80 90 100 40 50 60 70 80 pF1KB9 FAPAAALAASGRAETPQ--KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDN . . : .. : . .::::: :::::::. ::..:.::. :::.. : ::::. . NP_036 GSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKS 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB9 RQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGP . :::::::::::::::: ::::.. ::::.:::::: : ::.:::.::.. NP_036 KAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR------- 170 180 190 200 210 150 160 170 180 190 200 pF1KB9 GAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWP :: . . .. : .. :. ..: .. :. .::: :: . : NP_036 -----KRKSDVSSSTASLALEKTESSLPVDSPKTTE-------PQDILDGASPGGTTSSP 220 230 240 250 260 210 220 230 240 250 260 pF1KB9 GTASPNEDAGDAAQGAAAVAVGQAARTGDGPGS-PL-RPASRSSPKSSDKS-------KS :. . : . .. : .: .: : :: :. ::. :::. .: NP_036 -EKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGL--SPEPSDKTGQNSLTFNS 270 280 290 300 310 320 270 280 290 300 310 pF1KB9 FSIDSILAGKQGQKPPSGDELLGGAKPGPGGRL--GASLLAASSSLRPPFNASLMLDPHV :: . :....: .:: :.: : . : :.:.: :.. : : :. NP_036 FSPLTNLSNHSG----GGD----WANPMPTNMLSYGGSVL---SQFSPHFYNSVNTSGVL 330 340 350 360 370 320 330 340 pF1KB9 QGGFYQLGIPFLSYFPLQVPDTVLHFQ NP_036 YPREGTEV >>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa) initn: 531 init1: 492 opt: 546 Z-score: 322.7 bits: 68.6 E(85289): 3.1e-11 Smith-Waterman score: 562; 40.7% identity (59.0% similar) in 317 aa overlap (39-306:115-418) 10 20 30 40 50 60 pF1KB9 LPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQ-KPPYSYIALIAMAIQDAPE :.:: :..: ::::::::::.::: ..:. NP_004 GSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSG-AKNPLVKPPYSYIALITMAILQSPK 90 100 110 120 130 140 70 80 90 100 110 120 pF1KB9 QRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDP .:.::. : .:: :::.:... .:::::::::::::::::.::: : ::::.:::::: NP_004 KRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDP 150 160 170 180 190 200 130 140 150 160 170 180 pF1KB9 RCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGA-GGSG-PAISR . :::.::.. ::... : : : : : .::. :.:: ::.: :: . NP_004 ESADMFDNGSFLRRRKRFKRQPLLP----PNAA----AAESLLLRGAGAAGGAGDPAAAA 210 220 230 240 250 190 200 210 220 230 pF1KB9 LQAAPAGPSP-LLDGPSPPA---PLHWPGTASPNEDAGDAAQGAAAVAV----------- :: : : : .: . :. : : :. . :: .:::.: NP_004 ALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSALFAAAAAAAAAAAFHPHSPPPPPPP 260 270 280 290 300 310 240 250 260 270 pF1KB9 -GQAA---RTGDG----------PGS-PLRPASRSSPKSSDKSKS-FSIDSILAGKQG-- : :: ::. : :: : :. ..: .: ..: :::.::..:. : NP_004 HGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPGASALARSPFSIESIIGGSLGPA 320 330 340 350 360 370 280 290 300 310 pF1KB9 -------------QKPPSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQ : :: . . .: :.::. :. ::.... : NP_004 AAAAAAAQAAAAAQASPSPSPV--AAPPAPGSSGGGC--AAQAAVGPAAALTRSLVAAAA 380 390 400 410 420 430 320 330 340 pF1KB9 GGFYQLGIPFLSYFPLQVPDTVLHFQ NP_004 AAASSVSSSAALGTLHQGTALSSVENFTARISNC 440 450 460 345 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:37:58 2016 done: Fri Nov 4 17:37:59 2016 Total Scan time: 8.940 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]