FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9606, 359 aa 1>>>pF1KB9606 359 - 359 aa - 359 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0817+/-0.000738; mu= 6.6039+/- 0.045 mean_var=190.7908+/-37.218, 0's: 0 Z-trim(116.3): 5 B-trim: 0 in 0/54 Lambda= 0.092853 statistics sampled from 16895 (16897) to 16895 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.519), width: 16 Scan time: 3.480 The best scores are: opt bits E(32554) CCDS11495.1 HEXIM1 gene_id:10614|Hs108|chr17 ( 359) 2466 341.8 5.2e-94 CCDS11496.1 HEXIM2 gene_id:124790|Hs108|chr17 ( 286) 454 72.2 6e-13 >>CCDS11495.1 HEXIM1 gene_id:10614|Hs108|chr17 (359 aa) initn: 2466 init1: 2466 opt: 2466 Z-score: 1801.2 bits: 341.8 E(32554): 5.2e-94 Smith-Waterman score: 2466; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB9 MAEPFLSEYQHQPQTSNCTGAAAVQEELNPERPPGAEERVPEEDSRWQSRAFPQLGGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAEPFLSEYQHQPQTSNCTGAAAVQEELNPERPPGAEERVPEEDSRWQSRAFPQLGGRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEGEGSLESQPPPLQTQACPESSCLREGEKGQNGDDSSAGGDFPPPAEVEPTPEAELLAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PEGEGSLESQPPPLQTQACPESSCLREGEKGQNGDDSSAGGDFPPPAEVEPTPEAELLAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PCHDSEASKLGAPAAGGEEEWGQQQRQLGKKKHRRRPSKKKRHWKPYYKLTWEEKKKFDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PCHDSEASKLGAPAAGGEEEWGQQQRQLGKKKHRRRPSKKKRHWKPYYKLTWEEKKKFDE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KQSLRASRIRAEMFAKGQPVAPYNTTQFLMDDHDQEEPDLKTGLYSKRAAAKSDDTSDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KQSLRASRIRAEMFAKGQPVAPYNTTQFLMDDHDQEEPDLKTGLYSKRAAAKSDDTSDDD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FMEEGGEEDGGSDGMGGDGSEFLQRDFSETYERYHTESLQNMSKQELIKEYLELEKCLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FMEEGGEEDGGSDGMGGDGSEFLQRDFSETYERYHTESLQNMSKQELIKEYLELEKCLSR 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 MEDENNRLRLESKRLGGDDARVRELELELDRLRAENLQLLTENELHRQQERAPLSKFGD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEDENNRLRLESKRLGGDDARVRELELELDRLRAENLQLLTENELHRQQERAPLSKFGD 310 320 330 340 350 >>CCDS11496.1 HEXIM2 gene_id:124790|Hs108|chr17 (286 aa) initn: 749 init1: 396 opt: 454 Z-score: 345.9 bits: 72.2 E(32554): 6e-13 Smith-Waterman score: 683; 45.8% identity (64.3% similar) in 286 aa overlap (73-345:5-272) 50 60 70 80 90 pF1KB9 EDSRWQSRAFPQLGGRPGPEGEGSLESQPPPLQTQACPESSCLREGEK--GQNGDDSS-- : :: :: : : : :. .. CCDS11 MMATPNQTACNAESPVALEEAKTSGAPGSPQTPP 10 20 30 100 110 120 130 140 150 pF1KB9 ----AGGDFPPPAEVEPTPEAELLAQPCH----DSEASKLGAPAAGGEEEWGQQQRQLGK .::..: ..: : : :: .:.. . .: :: . . :.. CCDS11 ERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSP--GGC----SAEAVLAR 40 50 60 70 80 160 170 180 190 200 210 pF1KB9 KKHRRRPSKKKRHWKPYYKLTWEEKKKFDEKQSLRASRIRAEMFAKGQPVAPYNTTQFLM :::::::::.::::.:: .:.: ::.. ::.:: ::::.: ::::::::::::::::::: CCDS11 KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB9 DDHDQEEPDLKTGLYSKRAAAKSDDTSDDDFMEEGGEEDGGSDGMGGDGSEFLQRDFSET .:.: :::.: . . : :. : : : ::: : .:: ..::::: CCDS11 NDRDPEEPNLDV------PHGISHPGSS------GESEAGDSDGRGRAHGEFQRKDFSET 150 160 170 180 190 280 290 300 310 320 pF1KB9 YERYHTESLQNMSKQELIKEYLELEKCLSRMEDENNRLRLESKRLGGDDAR-VRELELEL :::.::::::. :::::...:::::: ::. :.:. ::. . : .. : :.:: :. CCDS11 YERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV 200 210 220 230 240 250 330 340 350 pF1KB9 DRLRAENLQLLTENELHRQQERAPLSKFGD .:::.:: .: ::.. CCDS11 QRLRTENQRLRQENQMWNREGCRCDEEPGT 260 270 280 359 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:38:33 2016 done: Fri Nov 4 17:38:34 2016 Total Scan time: 3.480 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]