FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9620, 347 aa 1>>>pF1KB9620 347 - 347 aa - 347 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3052+/-0.000375; mu= -2.3391+/- 0.024 mean_var=399.4195+/-81.063, 0's: 0 Z-trim(125.4): 8 B-trim: 0 in 0/59 Lambda= 0.064174 statistics sampled from 49061 (49069) to 49061 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.575), width: 16 Scan time: 11.140 The best scores are: opt bits E(85289) NP_005345 (OMIM: 165162) transcription factor jun- ( 347) 2260 222.4 1.2e-57 NP_001273897 (OMIM: 165162) transcription factor j ( 304) 1966 195.1 1.7e-49 NP_002219 (OMIM: 165160) transcription factor AP-1 ( 331) 731 80.8 4.7e-15 NP_002220 (OMIM: 165161) transcription factor jun- ( 347) 660 74.2 4.6e-13 >>NP_005345 (OMIM: 165162) transcription factor jun-D is (347 aa) initn: 2260 init1: 2260 opt: 2260 Z-score: 1156.1 bits: 222.4 E(85289): 1.2e-57 Smith-Waterman score: 2260; 100.0% identity (100.0% similar) in 347 aa overlap (1-347:1-347) 10 20 30 40 50 60 pF1KB9 METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKV 250 260 270 280 290 300 310 320 330 340 pF1KB9 KTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY ::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY 310 320 330 340 >>NP_001273897 (OMIM: 165162) transcription factor jun-D (304 aa) initn: 1966 init1: 1966 opt: 1966 Z-score: 1009.7 bits: 195.1 E(85289): 1.7e-49 Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 304 aa overlap (44-347:1-304) 20 30 40 50 60 70 pF1KB9 LGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAAAPPPTPL :::::::::::::::::::::::::::::: NP_001 MMKKDALTLSLSEQVAAALKPAAAPPPTPL 10 20 30 80 90 100 110 120 130 pF1KB9 RADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLYPKVAASEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLYPKVAASEE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB9 QEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPV 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB9 YANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFG 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB9 ESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELAST 220 230 240 250 260 270 320 330 340 pF1KB9 ASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY :::::::::::::::::::::::::::::::::: NP_001 ASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY 280 290 300 >>NP_002219 (OMIM: 165160) transcription factor AP-1 [Ho (331 aa) initn: 868 init1: 502 opt: 731 Z-score: 391.3 bits: 80.8 E(85289): 4.7e-15 Smith-Waterman score: 989; 52.8% identity (71.8% similar) in 362 aa overlap (1-347:5-331) 10 20 30 40 50 pF1KB9 METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSE ::: :: : ... . :: : ...: : :...::.:.. NP_002 MTAKMETTFYDDALNASFLPSESGPYG-YSNPKIL---------------KQSMTLNLAD 10 20 30 40 60 70 80 90 100 110 pF1KB9 QVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQS-NGLVT :.. ::: ::: .. ::.:::.::::::::::::::::: :: .: NP_002 PVGS-LKPH-------LRAKNSD-------LLTSPDVGLLKLASPELERLIIQSSNGHIT 50 60 70 80 120 130 140 150 160 170 pF1KB9 TTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAG--GPS-GT :::: .::: :: ...:.. ::::::.:: .::.:: : . ..:: . .:: .:. .. NP_002 TTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVAS 90 100 110 120 130 140 180 190 200 210 220 pF1KB9 ATGSAPPGELAPAAAAPEAPVYANLSSYAGGA----GGAG--GAATVAFAAEPVPFPPPP ..:.. : .. :. : :::::::.. :: ::: ::: .:: :.: :: NP_002 VAGGSGSGGFS-ASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPP 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB9 P--PGALGP---PRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIA : . : ::: :::.::::::..: ::.::::::::..::::::::::.::::: NP_002 HHLPQQM-PVQHPRLQALKEEPQTVPEMP--GETPPLSPIDMESQERIKAERKRMRNRIA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB9 ASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQ ::::::::::::.::::::::::.::.::::::..::::::::::::..::::::::. NP_002 ASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLT 270 280 290 300 310 320 pF1KB9 HQVPAY .:. .. NP_002 QQLQTF 330 >>NP_002220 (OMIM: 165161) transcription factor jun-B [H (347 aa) initn: 605 init1: 545 opt: 660 Z-score: 355.6 bits: 74.2 E(85289): 4.6e-13 Smith-Waterman score: 804; 45.0% identity (66.7% similar) in 369 aa overlap (1-339:5-339) 10 20 30 40 50 pF1KB9 METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSE :: ::: :.. .. : : . .: :. . : : .:...:.. NP_002 MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKP---------------SLAVNLAD 10 20 30 40 60 70 80 90 100 110 pF1KB9 QVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGL-LKLASPELERLII-QSNGLV . :: .: : : .. :. : .: : : ::::: ::::::. .:::.. NP_002 PYRS-LKAPGARGPGP-EGGGGGSYFSGQG----SDTGASLKLASSELERLIVPNSNGVI 50 60 70 80 90 120 130 140 150 pF1KB9 TTTPTS-SQFLYPKVAAS------------EEQE-FAEGFVKALEDLHKQNQLGA-GAAA ::::: .:..::. ..: :::: ::.::::::.::::.:.. ... NP_002 TTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSL 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB9 AAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPVYANLSSYA------GGAGGAGGAATV .:... .::.:. .: :: :::.:::::. ::::.: :... NP_002 GATGGPPAGPGGVYAGPEPP------------PVYTNLSSYSPASASSGGAGAAVGTGS- 160 170 180 190 200 220 230 240 250 260 pF1KB9 AFAAEPVPFPPPPPPGALGPP------RLAA-LKDEPQTVPDVPSFGESPPLSPIDMDTQ .. . . . : :: : : : : :. .:.::::::.. : .::.:::.:. : NP_002 SYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQ 210 220 230 240 250 260 270 280 290 300 310 320 pF1KB9 ERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQ ::::.::::::::.::.::::::::::.:::.::::::..:. :.:::.::::::::::: NP_002 ERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQ 270 280 290 300 310 320 330 340 pF1KB9 KVLSHVNSGCQLLPQHQVPAY ::..::..::::: NP_002 KVMTHVSNGCQLLLGVKGHAF 330 340 347 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 12:12:56 2016 done: Sun Nov 6 12:12:58 2016 Total Scan time: 11.140 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]