FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9623, 146 aa 1>>>pF1KB9623 146 - 146 aa - 146 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8489+/-0.000257; mu= 9.3027+/- 0.016 mean_var=73.3695+/-14.538, 0's: 0 Z-trim(121.5): 14 B-trim: 0 in 0/53 Lambda= 0.149733 statistics sampled from 38145 (38159) to 38145 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.447), width: 16 Scan time: 5.440 The best scores are: opt bits E(85289) NP_036449 (OMIM: 300402) protein LDOC1 [Homo sapie ( 146) 991 222.1 2.4e-58 NP_001071639 (OMIM: 300213) protein FAM127A [Homo ( 113) 432 101.3 4.4e-22 NP_001035242 (OMIM: 609810) retrotransposon-derive ( 325) 185 48.2 1.3e-05 NP_001171891 (OMIM: 609810) retrotransposon-derive ( 359) 185 48.2 1.4e-05 NP_001165909 (OMIM: 609810) retrotransposon-derive ( 401) 185 48.2 1.5e-05 NP_055883 (OMIM: 609810) retrotransposon-derived p ( 708) 185 48.3 2.5e-05 NP_001171890 (OMIM: 609810) retrotransposon-derive ( 742) 185 48.3 2.6e-05 NP_001165908 (OMIM: 609810) retrotransposon-derive ( 784) 185 48.3 2.8e-05 NP_001128360 (OMIM: 611896) retrotransposon-like p (1358) 185 48.4 4.5e-05 >>NP_036449 (OMIM: 300402) protein LDOC1 [Homo sapiens] (146 aa) initn: 991 init1: 991 opt: 991 Z-score: 1168.3 bits: 222.1 E(85289): 2.4e-58 Smith-Waterman score: 991; 100.0% identity (100.0% similar) in 146 aa overlap (1-146:1-146) 10 20 30 40 50 60 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRA 70 80 90 100 110 120 130 140 pF1KB9 FLDEMKQCFGWDDDEDDDDEEEEDDY :::::::::::::::::::::::::: NP_036 FLDEMKQCFGWDDDEDDDDEEEEDDY 130 140 >>NP_001071639 (OMIM: 300213) protein FAM127A [Homo sapi (113 aa) initn: 426 init1: 426 opt: 432 Z-score: 517.5 bits: 101.3 E(85289): 4.4e-22 Smith-Waterman score: 432; 58.7% identity (82.7% similar) in 104 aa overlap (37-136:9-112) 10 20 30 40 50 60 pF1KB9 LLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPS----CPVPFPETFNGESS .: : .:: . :.::::::.:... NP_001 MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTD 10 20 30 70 80 90 100 110 120 pF1KB9 RLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFL :::::::::.:::.:.:: : .::.::.:::. ::: : .::.:::. .::.:.:::.:: NP_001 RLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFL 40 50 60 70 80 90 130 140 pF1KB9 DEMKQCFGWDDDEDDDDEEEEDDY :::. :::..::: NP_001 AEMKRVFGWEEDEDF 100 110 >>NP_001035242 (OMIM: 609810) retrotransposon-derived pr (325 aa) initn: 253 init1: 182 opt: 185 Z-score: 221.9 bits: 48.2 E(85289): 1.3e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:7-158) 10 20 30 40 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRP-PS------- ::: .. : . : ::..:. :.. :. : ..: .::.: : NP_001 MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIE 10 20 30 40 50 60 50 60 70 80 90 pF1KB9 -----------------CPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAF :: .:: :.:. . : :..: .: . : : ..: : NP_001 LRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCF 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 LISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY . :..::.: .:. .: . .. .: ::. :::. : NP_001 VTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGS 130 140 150 160 170 180 NP_001 VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERR 190 200 210 220 230 240 >>NP_001171891 (OMIM: 609810) retrotransposon-derived pr (359 aa) initn: 233 init1: 182 opt: 185 Z-score: 221.2 bits: 48.2 E(85289): 1.4e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:41-192) 10 20 30 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRL ::: .. : . : ::..:. :.. NP_001 PPPPNNNNNNNSKHTGHKSACVPNMTERRRDELSEEINNLREKVMKQSEENNNLQSQVQK 20 30 40 50 60 70 40 50 60 pF1KB9 LVCERASLLRQVRP-PS------------------------CPVPFPETFNGESSRLPEF :. : ..: .::.: : :: .:: :.:. . : : NP_001 LTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPF 80 90 100 110 120 130 70 80 90 100 110 120 pF1KB9 IVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQ ..: .: . : : ..: :. :..::.: .:. .: . .. .: ::. :::. NP_001 MAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKH 140 150 160 170 180 190 130 140 pF1KB9 CFGWDDDEDDDDEEEEDDY : NP_001 VFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQE 200 210 220 230 240 250 >>NP_001165909 (OMIM: 609810) retrotransposon-derived pr (401 aa) initn: 233 init1: 182 opt: 185 Z-score: 220.5 bits: 48.2 E(85289): 1.5e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:83-234) 10 20 30 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRL ::: .. : . : ::..:. :.. NP_001 PPPPNNNNNNNSKHTGHKSACVPNMTERRRDELSEEINNLREKVMKQSEENNNLQSQVQK 60 70 80 90 100 110 40 50 60 pF1KB9 LVCERASLLRQVRP-PS------------------------CPVPFPETFNGESSRLPEF :. : ..: .::.: : :: .:: :.:. . : : NP_001 LTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPF 120 130 140 150 160 170 70 80 90 100 110 120 pF1KB9 IVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQ ..: .: . : : ..: :. :..::.: .:. .: . .. .: ::. :::. NP_001 MAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKH 180 190 200 210 220 230 130 140 pF1KB9 CFGWDDDEDDDDEEEEDDY : NP_001 VFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQE 240 250 260 270 280 290 >>NP_055883 (OMIM: 609810) retrotransposon-derived prote (708 aa) initn: 253 init1: 182 opt: 185 Z-score: 216.6 bits: 48.3 E(85289): 2.5e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:7-158) 10 20 30 40 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRP-PS------- ::: .. : . : ::..:. :.. :. : ..: .::.: : NP_055 MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIE 10 20 30 40 50 60 50 60 70 80 90 pF1KB9 -----------------CPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAF :: .:: :.:. . : :..: .: . : : ..: : NP_055 LRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCF 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 LISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY . :..::.: .:. .: . .. .: ::. :::. : NP_055 VTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGS 130 140 150 160 170 180 NP_055 VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERR 190 200 210 220 230 240 >>NP_001171890 (OMIM: 609810) retrotransposon-derived pr (742 aa) initn: 253 init1: 182 opt: 185 Z-score: 216.3 bits: 48.3 E(85289): 2.6e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:41-192) 10 20 30 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRL ::: .. : . : ::..:. :.. NP_001 PPPPNNNNNNNSKHTGHKSACVPNMTERRRDELSEEINNLREKVMKQSEENNNLQSQVQK 20 30 40 50 60 70 40 50 60 pF1KB9 LVCERASLLRQVRP-PS------------------------CPVPFPETFNGESSRLPEF :. : ..: .::.: : :: .:: :.:. . : : NP_001 LTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPF 80 90 100 110 120 130 70 80 90 100 110 120 pF1KB9 IVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQ ..: .: . : : ..: :. :..::.: .:. .: . .. .: ::. :::. NP_001 MAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKH 140 150 160 170 180 190 130 140 pF1KB9 CFGWDDDEDDDDEEEEDDY : NP_001 VFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQE 200 210 220 230 240 250 >>NP_001165908 (OMIM: 609810) retrotransposon-derived pr (784 aa) initn: 253 init1: 182 opt: 185 Z-score: 215.9 bits: 48.3 E(85289): 2.8e-05 Smith-Waterman score: 186; 28.3% identity (52.0% similar) in 152 aa overlap (3-129:83-234) 10 20 30 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRL ::: .. : . : ::..:. :.. NP_001 PPPPNNNNNNNSKHTGHKSACVPNMTERRRDELSEEINNLREKVMKQSEENNNLQSQVQK 60 70 80 90 100 110 40 50 60 pF1KB9 LVCERASLLRQVRP-PS------------------------CPVPFPETFNGESSRLPEF :. : ..: .::.: : :: .:: :.:. . : : NP_001 LTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPF 120 130 140 150 160 170 70 80 90 100 110 120 pF1KB9 IVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQ ..: .: . : : ..: :. :..::.: .:. .: . .. .: ::. :::. NP_001 MAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKH 180 190 200 210 220 230 130 140 pF1KB9 CFGWDDDEDDDDEEEEDDY : NP_001 VFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQE 240 250 260 270 280 290 >>NP_001128360 (OMIM: 611896) retrotransposon-like prote (1358 aa) initn: 150 init1: 150 opt: 185 Z-score: 212.1 bits: 48.4 E(85289): 4.5e-05 Smith-Waterman score: 185; 30.6% identity (60.3% similar) in 121 aa overlap (9-129:163-278) 10 20 30 pF1KB9 MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERA : :.. .: .. ..: :: : : :. NP_001 EEQEAHTDLKESGREETPQEQNQTEHSTAELMAMVRSIISLYFRMQDLKEQQR--VAEEI 140 150 160 170 180 190 40 50 60 70 80 90 pF1KB9 SLLRQVRPPSCPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTG :.. . . .: :. :.:. .. :::: . : :: ..:...:. :.: NP_001 -LIKGIN--AGQLPAPKHFSGDRREFHEFIVLCQLTLQSYPRMFYNDRLRVGYVINHLSG 200 210 220 230 240 100 110 120 130 140 pF1KB9 EAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY : ::. .. .::..::. :::. :.. : NP_001 LALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRVAEEAMFTIRQGGRSATEYIDE 250 260 270 280 290 300 NP_001 FQSLVPILGWPDEVLQAHLCQGLNEEIRHYLFRVPQPDSLDSLIVLILQIEEKLAERRAM 310 320 330 340 350 360 146 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:46:16 2016 done: Fri Nov 4 17:46:17 2016 Total Scan time: 5.440 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]