FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9635, 323 aa 1>>>pF1KB9635 323 - 323 aa - 323 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7429+/-0.000844; mu= 3.4112+/- 0.051 mean_var=249.6911+/-51.591, 0's: 0 Z-trim(116.7): 31 B-trim: 115 in 1/52 Lambda= 0.081166 statistics sampled from 17354 (17383) to 17354 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.534), width: 16 Scan time: 2.570 The best scores are: opt bits E(32554) CCDS13620.1 OLIG2 gene_id:10215|Hs108|chr21 ( 323) 2159 264.9 6.1e-71 CCDS5186.1 OLIG3 gene_id:167826|Hs108|chr6 ( 272) 613 83.8 1.7e-16 CCDS6179.1 BHLHE22 gene_id:27319|Hs108|chr8 ( 381) 455 65.4 8e-11 >>CCDS13620.1 OLIG2 gene_id:10215|Hs108|chr21 (323 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 1387.1 bits: 264.9 E(32554): 6.1e-71 Smith-Waterman score: 2159; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KB9 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV 250 260 270 280 290 300 310 320 pF1KB9 PPPHHHVSAMGAGSLPRLTSDAK ::::::::::::::::::::::: CCDS13 PPPHHHVSAMGAGSLPRLTSDAK 310 320 >>CCDS5186.1 OLIG3 gene_id:167826|Hs108|chr6 (272 aa) initn: 924 init1: 554 opt: 613 Z-score: 409.7 bits: 83.8 E(32554): 1.7e-16 Smith-Waterman score: 912; 50.2% identity (70.9% similar) in 323 aa overlap (1-323:1-268) 10 20 30 40 50 60 pF1KB9 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG :.::.: :::: :::. :...: . . . . ::: .: .. CCDS51 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKM--------- 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR ::..:. .: :. :. :: : :::..: .:::::::::.::::: CCDS51 -----PGESLSRAGAKA-----------AGESSKYKIKKQLSEQDLQQLRLKINGRERKR 60 70 80 90 130 140 150 160 170 180 pF1KB9 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH :::::.:::::::::::::::::::::::::::::::::::::.:::::::::.:::::: CCDS51 MHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS :..:: :: ..::: .::: ::...: :. :::: ..: ... :.. .:. CCDS51 HSAFH---CGTVGHSA------GHPAHAANSVH-PV--HPIL---GGALSSGNASSPLSA 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV :: ::..:.:::::.:::.::. : :: .:::::.:.::::..::. CCDS51 AS-----LPAIGTIRPPHSLLKAPSTPPALQLG---------SGFQHWAGLPCPCTICQM 210 220 230 240 310 320 pF1KB9 PPPHHHVSAMGAGSLPRLTSDAK ::: : .::...... ::....: CCDS51 PPPPH-LSALSTANMARLSAESKDLLK 250 260 270 >>CCDS6179.1 BHLHE22 gene_id:27319|Hs108|chr8 (381 aa) initn: 598 init1: 367 opt: 455 Z-score: 307.8 bits: 65.4 E(32554): 8e-11 Smith-Waterman score: 458; 44.2% identity (68.8% similar) in 224 aa overlap (23-241:167-372) 10 20 30 40 50 pF1KB9 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELS : : :..: ::. .. :. . . CCDS61 SVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGG----GGAKAAEGCSNAHLHGG 140 150 160 170 180 190 60 70 80 90 100 110 pF1KB9 AELR-GAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRL : . :..:..:. :.. :.:: ..:.: :...::...::.::.:.: . ::: CCDS61 ASVPPGGLGGGGGG-GSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ------KALRL 200 210 220 230 240 120 130 140 150 160 170 pF1KB9 KINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKR .::.:::.:::::: :.: :: :.::::.:::::::::::::::.::::: ...::::.: CCDS61 NINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRR 250 260 270 280 290 300 180 190 200 210 220 pF1KB9 LVSEIYGGH--HAGFHPSACGGLAHSAPLPAATAHPAAAAH--AAHHPAVHHPILPPAAA ::. . :. :. ::. .. : .: : ::: .:. :: .: :::::. CCDS61 LVAYLNQGQAISAASLPSSAAAAAAAAAL-----HPALGAYEQAAGYP--FSAGLPPAAS 310 320 330 340 350 230 240 250 260 270 280 pF1KB9 AAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQH : .:::. CCDS61 CPEKCALFNSVSSSLCKQCTEKP 360 370 380 323 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 01:04:31 2016 done: Tue Nov 8 01:04:32 2016 Total Scan time: 2.570 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]