FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9636, 272 aa 1>>>pF1KB9636 272 - 272 aa - 272 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6436+/-0.000734; mu= 11.4727+/- 0.045 mean_var=142.2726+/-28.602, 0's: 0 Z-trim(114.3): 28 B-trim: 0 in 0/52 Lambda= 0.107526 statistics sampled from 14871 (14899) to 14871 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.458), width: 16 Scan time: 2.840 The best scores are: opt bits E(32554) CCDS5186.1 OLIG3 gene_id:167826|Hs108|chr6 ( 272) 1827 294.0 7.6e-80 CCDS13620.1 OLIG2 gene_id:10215|Hs108|chr21 ( 323) 613 105.7 4.2e-23 CCDS6179.1 BHLHE22 gene_id:27319|Hs108|chr8 ( 381) 379 69.5 4e-12 >>CCDS5186.1 OLIG3 gene_id:167826|Hs108|chr6 (272 aa) initn: 1827 init1: 1827 opt: 1827 Z-score: 1547.0 bits: 294.0 E(32554): 7.6e-80 Smith-Waterman score: 1827; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272) 10 20 30 40 50 60 pF1KB9 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 AKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 LSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 VHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCP 190 200 210 220 230 240 250 260 270 pF1KB9 CTICQMPPPPHLSALSTANMARLSAESKDLLK :::::::::::::::::::::::::::::::: CCDS51 CTICQMPPPPHLSALSTANMARLSAESKDLLK 250 260 270 >>CCDS13620.1 OLIG2 gene_id:10215|Hs108|chr21 (323 aa) initn: 924 init1: 554 opt: 613 Z-score: 528.2 bits: 105.7 E(32554): 4.2e-23 Smith-Waterman score: 912; 50.2% identity (70.9% similar) in 323 aa overlap (1-268:1-323) 10 20 30 40 50 pF1KB9 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKM--------- :.::.: :::: :::. :...: . . . . ::: .: .. CCDS13 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG 10 20 30 40 50 60 60 70 80 90 pF1KB9 -----PGESLSRAGAKA-----------AGESSKYKIKKQLSEQDLQQLRLKINGRERKR ::..:. .: :. :. :: : :::..: .:::::::::.::::: CCDS13 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 MHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGH :::::.:::::::::::::::::::::::::::::::::::::.:::::::::.:::::: CCDS13 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH 130 140 150 160 170 180 160 170 180 190 200 pF1KB9 HSAFH---CGTVGHSA------GHPAHAANSVH-PV--HPIL---GGALSSGNASSPLSA :..:: :: ..::: .::: ::...: :. :::: ..: ... :.. .:. CCDS13 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS 190 200 210 220 230 240 210 220 230 240 pF1KB9 ASLP-----AIGTIRPPHSLLKAPSTPPALQLGSG---------FQHWAGLPCPCTICQM :::: ..:.:::::.:::.::. : ::.: ::::.:.::::..::. CCDS13 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV 250 260 270 280 290 300 250 260 270 pF1KB9 PPPPH-LSALSTANMARLSAESKDLLK ::: : .::...... ::....: CCDS13 PPPHHHVSAMGAGSLPRLTSDAK 310 320 >>CCDS6179.1 BHLHE22 gene_id:27319|Hs108|chr8 (381 aa) initn: 391 init1: 327 opt: 379 Z-score: 331.1 bits: 69.5 E(32554): 4e-12 Smith-Waterman score: 379; 50.3% identity (73.2% similar) in 153 aa overlap (53-205:217-356) 30 40 50 60 70 80 pF1KB9 RDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQ : : : .:..... ::. : .: :: . CCDS61 AHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSK---EQ--K 190 200 210 220 230 240 90 100 110 120 130 140 pF1KB9 QLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLE :::.::.:::.:::::: :.: :: :.::::.:::::::::::::::.::::: ...:: CCDS61 ALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALE 250 260 270 280 290 300 150 160 170 180 190 200 pF1KB9 EMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAAS ::.:::. . :. :. ... ::. : :: .:: ::. .. :. :.::. CCDS61 EMRRLVAYLNQGQ--AISAASLPSSAAAAAAAAA----LHPALGAYEQA--AGYPFSAGL 310 320 330 340 350 210 220 230 240 250 260 pF1KB9 LPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMAR :: CCDS61 PPAASCPEKCALFNSVSSSLCKQCTEKP 360 370 380 272 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:53:54 2016 done: Fri Nov 4 17:53:54 2016 Total Scan time: 2.840 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]