FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9637, 411 aa 1>>>pF1KB9637 411 - 411 aa - 411 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.5375+/- 0.001; mu= -14.3141+/- 0.059 mean_var=645.0388+/-163.426, 0's: 0 Z-trim(116.2): 49 B-trim: 0 in 0/53 Lambda= 0.050499 statistics sampled from 16720 (16753) to 16720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.515), width: 16 Scan time: 3.270 The best scores are: opt bits E(32554) CCDS5203.1 PLAGL1 gene_id:5325|Hs108|chr6 ( 411) 2862 223.2 3.5e-58 CCDS5202.1 PLAGL1 gene_id:5325|Hs108|chr6 ( 463) 2862 223.3 3.8e-58 CCDS13197.1 PLAGL2 gene_id:5326|Hs108|chr20 ( 496) 1096 94.7 2.1e-19 CCDS47860.1 PLAG1 gene_id:5324|Hs108|chr8 ( 418) 1028 89.6 5.9e-18 CCDS6165.1 PLAG1 gene_id:5324|Hs108|chr8 ( 500) 1028 89.7 6.7e-18 >>CCDS5203.1 PLAGL1 gene_id:5325|Hs108|chr6 (411 aa) initn: 2862 init1: 2862 opt: 2862 Z-score: 1158.0 bits: 223.2 E(32554): 3.5e-58 Smith-Waterman score: 2862; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411) 10 20 30 40 50 60 pF1KB9 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 HAASSGDLTCGVCALELGSTEVLLDHLKAHAEEKPPSGTKEKKHQCDHCERCFYTRKDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 HAASSGDLTCGVCALELGSTEVLLDHLKAHAEEKPPSGTKEKKHQCDHCERCFYTRKDVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMKESLQTGDLLSTFHTISPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 RHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMKESLQTGDLLSTFHTISPSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 QLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 QLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVSPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 SPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KGNAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 KGNAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLP 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 HRLSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAGTGSAILPHFHHAFR ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 HRLSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAGTGSAILPHFHHAFR 370 380 390 400 410 >>CCDS5202.1 PLAGL1 gene_id:5325|Hs108|chr6 (463 aa) initn: 2862 init1: 2862 opt: 2862 Z-score: 1157.4 bits: 223.3 E(32554): 3.8e-58 Smith-Waterman score: 2862; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:53-463) 10 20 30 pF1KB9 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQ :::::::::::::::::::::::::::::: CCDS52 NYSHSRERPYKCVQPDCGKAFVSRYKLMRHMATHSPQKSHQCAHCEKTFNRKDHLKNHLQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 THDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 THDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 AEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 AEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRH 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 TKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 TKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHS 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB9 LTLSPPEQAAQPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 LTLSPPEQAAQPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB9 KGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTIPASLDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 KGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTIPASLDLSP 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 LLGFWQLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTVSLGQLPLPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 LLGFWQLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTVSLGQLPLPPI 390 400 410 420 430 440 400 410 pF1KB9 PHVFSAGTGSAILPHFHHAFR ::::::::::::::::::::: CCDS52 PHVFSAGTGSAILPHFHHAFR 450 460 >>CCDS13197.1 PLAGL2 gene_id:5326|Hs108|chr20 (496 aa) initn: 588 init1: 473 opt: 1096 Z-score: 461.7 bits: 94.7 E(32554): 2.1e-19 Smith-Waterman score: 1096; 46.1% identity (68.2% similar) in 421 aa overlap (1-411:89-496) 10 20 30 pF1KB9 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQ ::::: :: ::: .:.: :.:::::.:::: CCDS13 SLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQ 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB9 THDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAH :::::: :. : ::::.::: :::.::::.::::::::.: :: . ::..::.::::: CCDS13 THDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAH 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB9 AEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRH .. . .:.::::: ::::.: :::::::::::::::: ::::::.:::::::::::::: CCDS13 SR-RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRH 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB9 TKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHS .::.:::::.: . . :.:. . . : . ..: : . ... : ....:. . CCDS13 VKKSHSQELLKIKTEPVDMLGLL-SCSSTVSVKEELSPVLCMASRDVMG-TKAFPGML-P 240 250 260 270 280 290 220 230 240 250 260 pF1KB9 LTLSPPEQAAQPMQPLPESLA--SL-----HP-SVSPGSPPPPLPNHKYNTTSTSYSPLA . . . ..: .:.::. .: .: :: : : :: ::. :::: : CCDS13 MGMYGAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPP-KYQLGSTSYLP-D 300 310 320 330 340 350 270 280 290 300 310 320 pF1KB9 SLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTI .:: :... .: : .: :. . :: .: : . .. : : ::. . CCDS13 KLP-KVEVDSFLA-ELPGSLSLSSAE-PQPASPQPAAAAALLDEALLAKS-PANLSEALC 360 370 380 390 400 330 340 350 360 370 380 pF1KB9 PASLDLSPLLGFW--QLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTV :..:.: :::: .::: .. :. ... . .:. : :. : : :. : : : . CCDS13 AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPL-LTTLQAQPQDSPGAGGPL 410 420 430 440 450 460 390 400 410 pF1KB9 SLGQLPLPPIPHVFSAGTGSAILPHFHHAFR ..: :: .: ::..: .:. ::.::.::. CCDS13 NFG--PLHSLPPVFTSGLSSTTLPRFHQAFQ 470 480 490 >>CCDS47860.1 PLAG1 gene_id:5324|Hs108|chr8 (418 aa) initn: 957 init1: 487 opt: 1028 Z-score: 435.8 bits: 89.6 E(32554): 5.9e-18 Smith-Waterman score: 1041; 44.3% identity (66.5% similar) in 427 aa overlap (1-411:1-418) 10 20 30 40 50 60 pF1KB9 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLAL ::::::.:.:.: .::: :.:::::::::.:::::: .: ::::::.::: ::.:::::: CCDS47 MATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 HAASSGDLTCGVCALELGSTEVLLDHLKAHAEEKPPSGTKEKKHQCDHCERCFYTRKDVR :::.:::::: :: . :: :::.:::.:: : .:.:::::::.::.: :::::::: CCDS47 HAATSGDLTCKVCLQTFESTGVLLEHLKSHAG-KSSGGVKEKKHQCEHCDRRFYTRKDVR 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 RHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMKESLQTGDLLSTFHTISPSF ::.::::: ::::::.:::::::::::::: ::.:.:::.: . . :.:. : : . : CCDS47 RHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPF-TCNVSV 120 130 140 150 160 170 190 200 210 220 230 pF1KB9 QLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVS-P .: :: . : .: :.. . .. . : :. : . ...: ... : CCDS47 PIKDELLPVMSLPSSEL--LSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 GSPPPPLPNH----KYNTTSTSYS---PLASLPLKADTKGFCNISLFEDLPL--QEPQSP . :.: :: .::::. : :::.. ... . : .: :. :. CCDS47 IDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL-MELQGGVPSSSQDSQAS 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 QKLNPGFDLAKGN----AGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTF .. . :.: :. :: ..: : . . :. :: ::.: :..: : : : . CCDS47 SSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPA-LDFSQLFNFIPLNGPP-YNPL 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB9 GNSTLALGPGESLPHR-LSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAG-TGSAILP . ..:... .. : .: : : :. .:..::.: . .:... . :. :: CCDS47 SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLH--SLSAAFTSSLSTSTTLP 360 370 380 390 400 410 410 pF1KB9 HFHHAFR .::.::. CCDS47 RFHQAFQ >>CCDS6165.1 PLAG1 gene_id:5324|Hs108|chr8 (500 aa) initn: 957 init1: 487 opt: 1028 Z-score: 434.9 bits: 89.7 E(32554): 6.7e-18 Smith-Waterman score: 1041; 44.3% identity (66.5% similar) in 427 aa overlap (1-411:83-500) 10 20 30 pF1KB9 MATHSPQKSHQCAHCEKTFNRKDHLKNHLQ ::::::.:.:.: .::: :.:::::::::. CCDS61 SYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLH 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB9 THDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAH :::::: .: ::::::.::: ::.:::::::::.:::::: :: . :: :::.:::.: CCDS61 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB9 AEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRH : : .:.:::::::.::.: ::::::::::.::::: ::::::.:::::::::::::: CCDS61 AG-KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRH 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB9 TKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHS ::.:.:::.: . . :.:. : : . : .: :: . : .: :.. . .. CCDS61 MKKSHNQELLKVKTEPVDFLDPF-TCNVSVPIKDELLPVMSLPSSEL--LSKPFTNTLQL 240 250 260 270 280 220 230 240 250 260 pF1KB9 LTLSPPEQAAQPMQPLPESLASLHPSVS-PGSPPPPLPNH----KYNTTSTSYS---PLA . : :. : . ...: ... : . :.: :: .::::. : CCDS61 NLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEK 290 300 310 320 330 340 270 280 290 300 310 pF1KB9 SLPLKADTKGFCNISLFEDLPL--QEPQSPQKLNPGFDLAKGN----AGKVNLPKELPAD :::.. ... . : .: :. :. .. . :.: :. :: ..: : . CCDS61 EQPLKGEIESYL-MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISI 350 360 370 380 390 400 320 330 340 350 360 370 pF1KB9 AVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLPHR-LSCLGQQQQEPPL . :. :: ::.: :..: : : : .. ..:... .. : .: : : :. CCDS61 SDPLNTPA-LDFSQLFNFIPLNGPP-YNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQD 410 420 430 440 450 460 380 390 400 410 pF1KB9 AMGTVSLGQLPLPPIPHVFSAG-TGSAILPHFHHAFR .:..::.: . .:... . :. ::.::.::. CCDS61 PANTIGLGSLH--SLSAAFTSSLSTSTTLPRFHQAFQ 470 480 490 500 411 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:54:26 2016 done: Fri Nov 4 17:54:26 2016 Total Scan time: 3.270 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]