FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9641, 322 aa
  1>>>pF1KB9641 322 - 322 aa - 322 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.4742+/-0.000392; mu= 8.9463+/- 0.025
 mean_var=266.8017+/-54.239, 0's: 0 Z-trim(121.4): 80  B-trim: 944 in 2/55
 Lambda= 0.078520
 statistics sampled from 37737 (37880) to 37737 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.444), width:  16
 Scan time:  9.030

The best scores are:                                      opt bits E(85289)
NP_005850 (OMIM: 600473,616158) transcriptional ac ( 322) 2151 256.4 5.7e-68
NP_150093 (OMIM: 608887) transcriptional activator ( 312)  753 98.0 2.6e-20


>>NP_005850 (OMIM: 600473,616158) transcriptional activa  (322 aa)
 initn: 2151 init1: 2151 opt: 2151  Z-score: 1341.3  bits: 256.4 E(85289): 5.7e-68
Smith-Waterman score: 2151; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)

               10        20        30        40        50        60
pF1KB9 MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 YAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 GSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEEPAELPEGTSLTVDNKRFFFDVGSNKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEEPAELPEGTSLTVDNKRFFFDVGSNKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GVFMRVSEVKPTYRNSITVPYKVWAKFGHTFCKYSEEMKKIQEKQREKRAACEQLHQQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GVFMRVSEVKPTYRNSITVPYKVWAKFGHTFCKYSEEMKKIQEKQREKRAACEQLHQQQQ
              250       260       270       280       290       300

              310       320  
pF1KB9 QQQEETAAATLLLQGEEEGEED
       ::::::::::::::::::::::
NP_005 QQQEETAAATLLLQGEEEGEED
              310       320  

>>NP_150093 (OMIM: 608887) transcriptional activator pro  (312 aa)
 initn: 1048 init1: 498 opt: 753  Z-score: 485.6  bits: 98.0 E(85289): 2.6e-20
Smith-Waterman score: 1270; 71.7% identity (83.6% similar) in 286 aa overlap (31-288:4-289)

               10        20        30        40        50        60
pF1KB9 MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQE
                                     : .:.  :::::  :   .. :: ..::::
NP_150                            MADGDSGSERGGGGGPCGFQPASRGGGEQETQE
                                          10        20        30   

               70        80        90       100       110       120
pF1KB9 LASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEH
       :::::.:::::::::::::::::::::::::::::.::::::::.::.:::: :::::::
NP_150 LASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEH
            40        50        60        70        80        90   

              130          140       150       160       170       
pF1KB9 YAQLGPSQPPDLAQAQDE---PRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRG
       :::::::.: .:: . .:   ::::::::::::::::::.::::::::::::::::::::
NP_150 YAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRG
           100       110       120       130       140       150   

              180        190       200       210                   
pF1KB9 -------PGLGSTQ-GQTIALPAQGLIEFRDALAKLIDDYGVEEE-----PA--------
              :: :. : :::::::::::::::::::::::::: :..     :.        
NP_150 GGGFGAGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGG
           160       170       180       190       200       210   

            220       230       240       250       260       270  
pF1KB9 ----ELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWAKFGHTFC
           :::::::.:::.:::::::: ::::::.:::::::.:::.::::.:.:.::: .::
NP_150 GLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFC
           220       230       240       250       260       270   

            280       290       300       310       320  
pF1KB9 KYSEEMKKIQEKQREKRAACEQLHQQQQQQQEETAAATLLLQGEEEGEED
       .:..:::.:::.::.:                                  
NP_150 RYADEMKEIQERQRDKLYERRGGGSGGGEESEGEEVDED           
           280       290       300       310             




322 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:55:49 2016 done: Fri Nov  4 17:55:50 2016
 Total Scan time:  9.030 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]