FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9649, 441 aa
  1>>>pF1KB9649 441 - 441 aa - 441 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.6813+/-0.000815; mu= 5.6134+/- 0.050
 mean_var=247.3238+/-50.350, 0's: 0 Z-trim(116.3): 52  B-trim: 0 in 0/54
 Lambda= 0.081553
 statistics sampled from 16872 (16924) to 16872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.52), width:  16
 Scan time:  3.850

The best scores are:                                      opt bits E(32554)
CCDS1654.1 SOX11 gene_id:6664|Hs108|chr2           ( 441) 2950 359.6 3.7e-99
CCDS4547.1 SOX4 gene_id:6659|Hs108|chr6            ( 474)  718 97.0 4.4e-20
CCDS12995.1 SOX12 gene_id:6666|Hs108|chr20         ( 315)  586 81.3 1.6e-15


>>CCDS1654.1 SOX11 gene_id:6664|Hs108|chr2                (441 aa)
 initn: 2950 init1: 2950 opt: 2950  Z-score: 1893.7  bits: 359.6 E(32554): 3.7e-99
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 441 aa overlap (1-441:1-441)

               10        20        30        40        50        60
pF1KB9 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE
              370       380       390       400       410       420

              430       440 
pF1KB9 LSEMIAGDWLEANFSDLVFTY
       :::::::::::::::::::::
CCDS16 LSEMIAGDWLEANFSDLVFTY
              430       440 

>>CCDS4547.1 SOX4 gene_id:6659|Hs108|chr6                 (474 aa)
 initn: 1098 init1: 628 opt: 718  Z-score: 474.1  bits: 97.0 E(32554): 4.4e-20
Smith-Waterman score: 1010; 43.8% identity (64.6% similar) in 491 aa overlap (1-441:1-474)

                10        20          30               40        50
pF1KB9 MVQQAESLE-AESNLPREALDTEEG-EF-MACSPVALDES-------DPDWCKTASGHIK
       ::::... : .:. :  :. :.  : :. .: ::.  . .       ::.:::: :::::
CCDS45 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB9 RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM
       ::::::::::.:::::::::::::::::::::::::::.::::.::::::::::::::::
CCDS45 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
               70        80        90       100       110       120

              120          130        140         150       160    
pF1KB9 ADYPDYKYRPRKKPK---MDPSAKPSASQSP-EKS--AAGGGGGSAGGGAGGAKTSKGSS
       ::::::::::::: :    . :.. .::..: ::.  ..:.:::. :::.::.... :..
CCDS45 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
              130       140       150       160       170       180

          170       180       190       200       210       220    
pF1KB9 KKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCV---F
          :   . ..:..: .  :.  :   ::::        ..  .::::.::..  .   :
CCDS45 ---GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASF
                 190       200       210       220       230       

                   230       240          250       260         270
pF1KB9 LDEDDDD------DDDDDELQLQIKQEPDEE---DEEPPHQQLLQPPGQQ--PSQLLRRY
         :.             :. .:   . :.     .     .  :  ::..   ... : :
CCDS45 AAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVY
       240       250       260       270       280       290       

                280         290       300                     310  
pF1KB9 NVAKV--PASPT--LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL-
         . .   .::.  ....:.  .  .::.:  ::              :.: :.: :   
CCDS45 LFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPAD
       300       310       320       330       340       350       

             320       330       340       350       360       370 
pF1KB9 YYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQ
       . .. ..    : : . :  : ::: . : ::::::..::.:. :  :::   :.:: :.
CCDS45 HRGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPSS
       360       370         380       390       400          410  

             380       390       400        410       420       430
pF1KB9 SAHSASEQQLGGGAAAGNLSLSLVDKDLD-SFSEGSLGSHFEFPDYCTPELSEMIAGDWL
       . .: :   ::. ...     : .:.::: .:  :: :::::::::::::.::::.::::
CCDS45 NFESMS---LGSFSSS-----SALDRDLDFNFEPGS-GSHFEFPDYCTPEVSEMISGDWL
               420            430       440        450       460   

              440 
pF1KB9 EANFSDLVFTY
       :...:.:::::
CCDS45 ESSISNLVFTY
           470    

>>CCDS12995.1 SOX12 gene_id:6666|Hs108|chr20              (315 aa)
 initn: 820 init1: 562 opt: 586  Z-score: 392.4  bits: 81.3 E(32554): 1.6e-15
Smith-Waterman score: 720; 39.6% identity (55.1% similar) in 412 aa overlap (31-441:22-315)

               10        20        30        40        50        60
pF1KB9 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
                                     :.     .: :::: :::::::::::::::
CCDS12          MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWS
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KB9 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
       . ::::::.: :::::::::::::.::..:.:::::::.:::::::::::::::::::::
CCDS12 QHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRP
              60        70        80        90       100       110 

               130       140       150       160       170         
pF1KB9 RKKPKMDPS-AKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAK
       ::: :  :. :.:   . :            ::..::.. . :        . :. .: .
CCDS12 RKKSKGAPAKARP---RPP------------GGSGGGSRLKPGP-------QLPGRGGRR
             120                      130       140                

     180       190       200       210       220       230         
pF1KB9 AGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQI
       : ::                       :  ::::.          .:::.:::.:: :..
CCDS12 A-AG-----------------------GPLGGGAAAP--------EDDDEDDDEEL-LEV
     150                               160               170       

     240       250       260       270       280       290         
pF1KB9 KQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRA
       .              :.. ::..    : :.    :::. .  ..::           ::
CCDS12 R--------------LVETPGRE----LWRM----VPAGRAARGQAE-----------RA
                      180               190       200              

     300       310       320       330       340       350         
pF1KB9 GATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDAD
        . :: :..                  :  : ::. :..          ....  ::.  
CCDS12 QGPSGEGAA------------------AAAAASPTPSED-EEPEEEEEEAAAAEEGEEET
           210                         220        230       240    

     360       370       380       390       400       410         
pF1KB9 DLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTP
           . ::.: .        .:  : :.  :. : .:.: : ..  :  :::::::::::
CCDS12 VASGEESLGFLS--------RLPPGPAG--LDCSALDRDPD-LQPPSGTSHFEFPDYCTP
          250               260         270        280       290   

     420       430       440 
pF1KB9 ELSEMIAGDWLEANFSDLVFTY
       :..:::::::  ....::::::
CCDS12 EVTEMIAGDWRPSSIADLVFTY
           300       310     




441 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:57:26 2016 done: Fri Nov  4 17:57:26 2016
 Total Scan time:  3.850 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]