FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9651, 240 aa 1>>>pF1KB9651 240 - 240 aa - 240 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0622+/-0.000315; mu= 7.5388+/- 0.020 mean_var=132.9937+/-27.790, 0's: 0 Z-trim(120.5): 195 B-trim: 281 in 1/56 Lambda= 0.111214 statistics sampled from 35568 (35774) to 35568 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.419), width: 16 Scan time: 7.430 The best scores are: opt bits E(85289) NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 1655 276.0 4e-74 NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 664 117.1 3.3e-26 NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 601 107.0 4e-23 NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 602 107.2 4.2e-23 NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 555 99.7 8.7e-21 NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 474 86.5 4.3e-17 NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 435 80.4 5.2e-15 NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 414 77.1 5e-14 NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 408 76.1 9.9e-14 NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 402 74.9 1.2e-13 NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 405 75.7 1.7e-13 NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 404 75.5 1.7e-13 NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 400 74.8 2.7e-13 NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 394 73.8 4e-13 NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 394 73.9 5.5e-13 NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 391 73.4 7.5e-13 XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 349 66.8 1e-10 NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 349 66.8 1e-10 NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 339 65.0 2.1e-10 XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 339 65.0 2.2e-10 NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 339 65.2 3.2e-10 XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 339 65.2 3.4e-10 XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 339 65.2 3.4e-10 XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 339 65.2 3.4e-10 XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 339 65.2 3.4e-10 XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 339 65.2 3.4e-10 NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 339 65.2 3.5e-10 XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 339 65.2 3.5e-10 NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 339 65.2 3.6e-10 XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 339 65.2 3.6e-10 XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 339 65.2 3.6e-10 NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 339 65.2 3.6e-10 XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 339 65.2 3.6e-10 NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 339 65.2 3.6e-10 XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 339 65.2 3.6e-10 XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 339 65.2 3.7e-10 XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 339 65.2 3.7e-10 NP_001139283 (OMIM: 607257) transcription factor S ( 801) 327 63.3 1.4e-09 NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 327 63.3 1.4e-09 NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 327 63.3 1.4e-09 NP_001139291 (OMIM: 607257) transcription factor S ( 841) 327 63.3 1.5e-09 XP_005265860 (OMIM: 606698) PREDICTED: transcripti ( 448) 317 61.5 2.7e-09 >>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa) initn: 1655 init1: 1655 opt: 1655 Z-score: 1451.8 bits: 276.0 E(85289): 4e-74 Smith-Waterman score: 1655; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 APEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM 190 200 210 220 230 240 >>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa) initn: 1046 init1: 627 opt: 664 Z-score: 591.6 bits: 117.1 E(85289): 3.3e-26 Smith-Waterman score: 965; 58.0% identity (73.3% similar) in 281 aa overlap (1-236:1-272) 10 20 30 40 50 60 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE :::: ::.::::::::::::.::::::::::::::::::::::::::::.:.::::.::: NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPY-LG---DTD-P-LKA-AGLPVG ::::::.:::::::::::::::::.:::::...::.:: :: :.. : ::: ::: .: NP_009 AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 70 80 90 100 110 120 120 130 140 pF1KB9 ASDGL-----LSAPEKA---------RAFLPPASA-------------PYSLLDPAQFSS :. :: :. :::: :.:.: ..: :::::: .. NP_009 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGS--- 130 140 150 160 170 150 160 170 180 190 pF1KB9 SAIQKMGEVPHTLATGALPYASTLGYQN---GAF-GSLSCPSQ-------HTHTHPSPTN ::.:. . ...:::::.::: . ::: :. . . :::.:::: : NP_009 ----KMAEISSS--SSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGN 180 190 200 210 220 230 200 210 220 230 240 pF1KB9 PGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM :::..::::.:: . ::::.::::.::: : .::: .:. NP_009 PGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL 240 250 260 270 >>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa) initn: 626 init1: 574 opt: 601 Z-score: 536.1 bits: 107.0 E(85289): 4e-23 Smith-Waterman score: 601; 49.1% identity (69.1% similar) in 220 aa overlap (6-216:39-254) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN :..::::::::::::::::::::::::::: NP_003 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP ::::::::::::::::.::::.::::::::: ::::::::::::::: :.:.:::.:..: NP_003 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 LPYLGDTDPLKAAGLPVGASDGL-LSAPEKARAFLPPAS-APYSLLD-----PAQFSSSA :. :.:. :::. : .. . : . : . ::... : . . .: NP_003 GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNA 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 IQKMGEVP-HTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPC-NCTA : : ..:: : : . :. :: :. .. .. . .::... . .. NP_003 HGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS---PT-YSMSYSQQGTPGMALGSMGSVV 190 200 210 220 230 240 210 220 230 240 pF1KB9 WSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM : .. .::: NP_003 KSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVP 250 260 270 280 290 300 >>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa) initn: 590 init1: 563 opt: 602 Z-score: 535.7 bits: 107.2 E(85289): 4.2e-23 Smith-Waterman score: 602; 46.5% identity (64.7% similar) in 241 aa overlap (6-239:49-285) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN :..::::::::::::::::::::::::::: NP_005 PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHN 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP ::::::::::::..:::::::.::::::::: ::::::::::::::: :.:::::.: . NP_005 SEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLA 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 LPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEV :. .:.. .:.. :. .: : : ..: . ....: : : NP_005 GGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYP--GSV 140 150 160 170 180 190 160 170 180 190 200 pF1KB9 PHTLATGALPYASTLGY--QNGAFGSL-----SCPSQHTHTHPSPTNPGYVVPCNCTAWS . :..:. . :.: . :: :. . : : : : : :: . . : . NP_005 AAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPH-HPHAHPHNPQPMHRYDMGALQ 200 210 220 230 240 250 210 220 230 240 pF1KB9 ASTLQPPVAYILFPGMTKTGIDPYSSAHATAM : .. .:. :. ::..: :.: NP_005 YSPISNSQGYMSASPSGYGGL-PYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGAL 260 270 280 290 300 310 NP_005 GSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQH 320 330 340 350 360 370 >>NP_005625 (OMIM: 300123,312000,313430) transcription f (446 aa) initn: 541 init1: 541 opt: 555 Z-score: 494.1 bits: 99.7 E(85289): 8.7e-21 Smith-Waterman score: 555; 45.6% identity (67.3% similar) in 217 aa overlap (6-215:137-352) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN :..::::::::::::::::::: ::::::: NP_005 GKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHN 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB9 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP :::::::::.::::..:::::.::::::::: ::::.:::::::::: :.:::::.: .: NP_005 SEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLP 170 180 190 200 210 220 100 110 120 130 140 150 pF1KB9 LPYL--GDTDPLKAAGLPVGASDGLLSAPEKARAFLPP---ASAPYSLLDPAQFSSSAIQ : : . ::. ..:... ... .. .. :.. :::.. :.. . NP_005 SGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQE-QLGYAQPP 230 240 250 260 270 280 160 170 180 190 200 pF1KB9 KMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGY--VVPCNCTAWS .:. : : . . : : . . . : . . . . :: ..: .: . NP_005 SMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAA 290 300 310 320 330 340 210 220 230 240 pF1KB9 ASTLQPPVAYILFPGMTKTGIDPYSSAHATAM :. : : NP_005 AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYL 350 360 370 380 390 400 >>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa) initn: 465 init1: 445 opt: 474 Z-score: 427.9 bits: 86.5 E(85289): 4.3e-17 Smith-Waterman score: 474; 48.1% identity (71.2% similar) in 156 aa overlap (4-159:45-192) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKM : ...::::::::::: .:::.:::.:::: NP_008 EPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKM 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 HNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV :::::::::::.::::.: ::::...:::::::.:....:::::::::: :. . NP_008 HNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS-----SGA 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 FPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMG : :. :.: :. . . : .. .. ::. . : :....:: . . NP_008 GP-SRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYL--PGSYGSSHCKLEA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 EVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQ : .: NP_008 PSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL 190 200 210 220 230 >>NP_071899 (OMIM: 610928,613674) transcription factor S (414 aa) initn: 409 init1: 388 opt: 435 Z-score: 390.5 bits: 80.4 E(85289): 5.2e-15 Smith-Waterman score: 435; 37.7% identity (60.3% similar) in 247 aa overlap (2-236:62-294) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENP .: ..:.:::::::::.. .:...::.:: NP_071 WAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNP 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB9 KMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDR .::.:.:: :: :: :. :::::...::.:::.:::..::.:::::::. . .:. . NP_071 DLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ--VKRLK 100 110 120 130 140 100 110 120 130 140 pF1KB9 YVFPLPYLGDTDPLKAAGLPVG---ASDGL-LSAPEKARAFLPPASAPYSLLDPAQFSS- : : ..: :: : : : ::: :. ::.. : ::. : :: : . . NP_071 RVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQFPEQG--F--PAGPP--LLPPHMGGHY 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB9 SAIQKMGEVPHTLATGALPYASTL-GYQ-NGAFGSL----SCPSQHTHTHPSPTNPGYVV :..: : : .: : : . . :: . .::. :... . .. :. NP_071 RDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSD--YAG 210 220 230 240 250 260 210 220 230 240 pF1KB9 PCNCTAWSAST-LQPPVAYILFPGMTKTGIDPYSSAHATAM : . : : : : .::. . : :. : NP_071 PPEPPAGPMHPRLGPEPAGPSIPGL----LAPPSALHVYYGAMGSPGAGGGRGFQMQPQH 270 280 290 300 310 NP_071 QHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGL 320 330 340 350 360 370 >>NP_060889 (OMIM: 137940,601618,607823) transcription f (384 aa) initn: 434 init1: 367 opt: 414 Z-score: 372.8 bits: 77.1 E(85289): 5e-14 Smith-Waterman score: 433; 36.5% identity (59.2% similar) in 260 aa overlap (8-232:85-330) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSE :.:::::::::.. .:...::.:: .::. NP_060 QRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAV 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB9 ISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP-- .:: :: :: :. :::::...::.:::.::...::.:::::::: . .: : . : NP_060 LSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQA--RKARRLEPGL 120 130 140 150 160 170 100 110 120 130 pF1KB9 -LPYLGDT----DPLKAAGL---------PVGAS-DGL-LSAPEKA---------RAFLP :: :. .:. ::. :.:: ::: : .::.. ::.: NP_060 LLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFP 180 190 200 210 220 230 140 150 160 170 180 pF1KB9 PASAPYSL-LDP--AQFSSSAIQK-----MGEVPHTLATGALPYASTLGYQNGAFGSLSC : .:: . : : : .. . ... .: .: . : . : :. :. . .:.:. NP_060 PPAAPEDCALRPFRAPYAPTELSRDPGGCYG-APLAEALRTAPPAAPLA--GLYYGTLGT 240 250 260 270 280 190 200 210 220 230 240 pF1KB9 PSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM :. .:.: .: .: :: : : : :. . : .: : NP_060 PG----PYPGPLSPPPEAP---PLESAEPLGP--AADLWADVDLTEFDQYLNCSRTRPDA 290 300 310 320 330 340 NP_060 PGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG 350 360 370 380 >>NP_113627 (OMIM: 612202) transcription factor SOX-7 [H (388 aa) initn: 390 init1: 369 opt: 408 Z-score: 367.5 bits: 76.1 E(85289): 9.9e-14 Smith-Waterman score: 408; 40.2% identity (59.8% similar) in 204 aa overlap (8-198:45-240) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSE :.:::::::::.. .:...: .:: .::.: NP_113 ECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAE 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 ISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKP--KNLLKKDRYVFP .:: :: :: :. ..::::.:::.::: :::...:.:::::::: : : :. : NP_113 LSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFL 80 90 100 110 120 130 100 110 120 130 140 pF1KB9 LPYLG-DTD--PLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLD-----PAQFSSS : :. : . : : .: : : :. : :. :..: :: :: ... NP_113 LSSLSRDQNALPEKRSG-----SRGALGEKED-RGEYSPGTALPSLRGCYHEGPAGGGGG 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 AI-QKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPS--PTNPGYVVPCNC . ... :. : : : : : . .: : :. : :: : ::. NP_113 GTPSSVDTYPYGLPTP--PEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEY 190 200 210 220 230 240 210 220 230 240 pF1KB9 TAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM NP_113 APSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPP 250 260 270 280 290 300 >>NP_003131 (OMIM: 400044,400045,480000) sex-determining (204 aa) initn: 404 init1: 386 opt: 402 Z-score: 366.3 bits: 74.9 E(85289): 1.2e-13 Smith-Waterman score: 402; 62.2% identity (88.9% similar) in 90 aa overlap (6-95:58-146) 10 20 30 pF1KB9 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN :..:::::::.:::: :::::: :::.:.: NP_003 LRRSSSFLCTESCNSKYQCETGENSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRN 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP :::::.:: .::.:.:::: :...::..:.:.: ...:.:::::::: : .: :. ..: NP_003 SEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAK-MLPKNCSLLP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 LPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEV NP_003 ADPASVLCSEVQLDNRLYRDDCTKATHSRMEHQLGHLPPINAASSPQQRDRYSHWTKL 150 160 170 180 190 200 240 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:58:02 2016 done: Fri Nov 4 17:58:03 2016 Total Scan time: 7.430 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]