FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9658, 323 aa 1>>>pF1KB9658 323 - 323 aa - 323 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9977+/-0.000318; mu= 2.0816+/- 0.020 mean_var=243.0165+/-50.420, 0's: 0 Z-trim(124.6): 35 B-trim: 1521 in 1/58 Lambda= 0.082273 statistics sampled from 46463 (46516) to 46463 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.831), E-opt: 0.2 (0.545), width: 16 Scan time: 9.230 The best scores are: opt bits E(85289) NP_005452 (OMIM: 166300,608968,617041) transcripti ( 323) 2239 277.7 2.2e-74 NP_001026974 (OMIM: 177075,601088,610202) transcri ( 373) 707 95.9 1.4e-19 XP_016878722 (OMIM: 177075,601088,610202) PREDICTE ( 383) 707 95.9 1.4e-19 XP_016878724 (OMIM: 177075,601088,610202) PREDICTE ( 383) 707 95.9 1.4e-19 XP_016878723 (OMIM: 177075,601088,610202) PREDICTE ( 383) 707 95.9 1.4e-19 NP_005351 (OMIM: 177075,601088,610202) transcripti ( 403) 706 95.8 1.6e-19 NP_963883 (OMIM: 610303) transcription factor MafA ( 353) 581 81.0 4.1e-15 XP_011535108 (OMIM: 162080,613750) PREDICTED: neur ( 234) 442 64.3 2.8e-10 NP_006168 (OMIM: 162080,613750) neural retina-spec ( 237) 439 64.0 3.7e-10 XP_005267766 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_011535104 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_011535107 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_011535106 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_005267765 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_005267767 (OMIM: 162080,613750) PREDICTED: neur ( 237) 439 64.0 3.7e-10 XP_011535103 (OMIM: 162080,613750) PREDICTED: neur ( 339) 439 64.1 4.8e-10 XP_016876839 (OMIM: 162080,613750) PREDICTED: neur ( 132) 423 61.8 8.9e-10 XP_005249908 (OMIM: 600197) PREDICTED: transcripti ( 156) 380 56.8 3.4e-08 NP_002351 (OMIM: 600197) transcription factor MafK ( 156) 380 56.8 3.4e-08 XP_006715836 (OMIM: 600197) PREDICTED: transcripti ( 156) 380 56.8 3.4e-08 NP_116100 (OMIM: 602020) transcription factor MafG ( 162) 368 55.4 9.5e-08 NP_002350 (OMIM: 602020) transcription factor MafG ( 162) 368 55.4 9.5e-08 XP_011521880 (OMIM: 602020) PREDICTED: transcripti ( 162) 368 55.4 9.5e-08 NP_001155044 (OMIM: 604877) transcription factor M ( 164) 344 52.5 6.9e-07 NP_001155045 (OMIM: 604877) transcription factor M ( 164) 344 52.5 6.9e-07 NP_036455 (OMIM: 604877) transcription factor MafF ( 164) 344 52.5 6.9e-07 NP_001155046 (OMIM: 604877) transcription factor M ( 135) 324 50.1 3.1e-06 >>NP_005452 (OMIM: 166300,608968,617041) transcription f (323 aa) initn: 2239 init1: 2239 opt: 2239 Z-score: 1456.3 bits: 277.7 E(85289): 2.2e-74 Smith-Waterman score: 2239; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 STPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LQSFDSFRGAHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LQSFDSFRGAHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 QQLPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QQLPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 QKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEK 250 260 270 280 290 300 310 320 pF1KB9 LANSGFREAGSTSDSPSSPEFFL ::::::::::::::::::::::: NP_005 LANSGFREAGSTSDSPSSPEFFL 310 320 >>NP_001026974 (OMIM: 177075,601088,610202) transcriptio (373 aa) initn: 1072 init1: 642 opt: 707 Z-score: 472.7 bits: 95.9 E(85289): 1.4e-19 Smith-Waterman score: 1060; 52.6% identity (70.2% similar) in 359 aa overlap (18-323:19-373) 10 20 30 40 50 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTP :::::::::.::.:::::. ...: : :: .::.:::: NP_001 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPV-ETDRIISQCGRLIAGGSLSSTP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LSTPCSSVPSSPSFS-PT-----EQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIG .:::::::: ::::: :. :::.:::: :::.. ::.:::::...:::::::::. NP_001 MSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALIS 60 70 80 90 100 110 120 130 140 150 pF1KB9 -SHPVPQPLQSFDSF-RGAHHHHHHHHPHPHHAYPGAG-----------------VAHDE :: : .::.. :::.. . :.: .:.. NP_001 NSH---QLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSG 120 130 140 150 160 170 160 170 180 190 200 pF1KB9 LGPHAHPHHHH-----HHQASPPPSSAASPAQQLP-TSHPGPGPHATASATAAGGNGS-- ::: : :::: :: .. :..:.: : . .. : : :.:.. ..::.:. NP_001 AGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGG 180 190 200 210 220 230 210 220 230 240 pF1KB9 --------------------VEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTL .:::::.:::.::::::::.::: .:.:::::::::::: NP_001 GGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTL 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 KNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGF ::::::::::.:::::.: ::.::.::.:::..::::.:::.::::::: : :::..::: NP_001 KNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGF 300 310 320 330 340 350 310 320 pF1KB9 REAGSTSDSPSSPEFFL :: ::.::.:::::::. NP_001 RENGSSSDNPSSPEFFM 360 370 >>XP_016878722 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 1072 init1: 642 opt: 707 Z-score: 472.6 bits: 95.9 E(85289): 1.4e-19 Smith-Waterman score: 1060; 52.6% identity (70.2% similar) in 359 aa overlap (18-323:19-373) 10 20 30 40 50 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTP :::::::::.::.:::::. ...: : :: .::.:::: XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPV-ETDRIISQCGRLIAGGSLSSTP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LSTPCSSVPSSPSFS-PT-----EQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIG .:::::::: ::::: :. :::.:::: :::.. ::.:::::...:::::::::. XP_016 MSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALIS 60 70 80 90 100 110 120 130 140 150 pF1KB9 -SHPVPQPLQSFDSF-RGAHHHHHHHHPHPHHAYPGAG-----------------VAHDE :: : .::.. :::.. . :.: .:.. XP_016 NSH---QLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSG 120 130 140 150 160 170 160 170 180 190 200 pF1KB9 LGPHAHPHHHH-----HHQASPPPSSAASPAQQLP-TSHPGPGPHATASATAAGGNGS-- ::: : :::: :: .. :..:.: : . .. : : :.:.. ..::.:. XP_016 AGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGG 180 190 200 210 220 230 210 220 230 240 pF1KB9 --------------------VEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTL .:::::.:::.::::::::.::: .:.:::::::::::: XP_016 GGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTL 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 KNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGF ::::::::::.:::::.: ::.::.::.:::..::::.:::.::::::: : :::..::: XP_016 KNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGF 300 310 320 330 340 350 310 320 pF1KB9 REAGSTSDSPSSPEFFL :: ::.::.:::::::. XP_016 RENGSSSDNPSSPEFFMYPRESSTSVM 360 370 380 >>XP_016878724 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 1072 init1: 642 opt: 707 Z-score: 472.6 bits: 95.9 E(85289): 1.4e-19 Smith-Waterman score: 1060; 52.6% identity (70.2% similar) in 359 aa overlap (18-323:19-373) 10 20 30 40 50 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTP :::::::::.::.:::::. ...: : :: .::.:::: XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPV-ETDRIISQCGRLIAGGSLSSTP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LSTPCSSVPSSPSFS-PT-----EQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIG .:::::::: ::::: :. :::.:::: :::.. ::.:::::...:::::::::. XP_016 MSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALIS 60 70 80 90 100 110 120 130 140 150 pF1KB9 -SHPVPQPLQSFDSF-RGAHHHHHHHHPHPHHAYPGAG-----------------VAHDE :: : .::.. :::.. . :.: .:.. XP_016 NSH---QLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSG 120 130 140 150 160 170 160 170 180 190 200 pF1KB9 LGPHAHPHHHH-----HHQASPPPSSAASPAQQLP-TSHPGPGPHATASATAAGGNGS-- ::: : :::: :: .. :..:.: : . .. : : :.:.. ..::.:. XP_016 AGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGG 180 190 200 210 220 230 210 220 230 240 pF1KB9 --------------------VEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTL .:::::.:::.::::::::.::: .:.:::::::::::: XP_016 GGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTL 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 KNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGF ::::::::::.:::::.: ::.::.::.:::..::::.:::.::::::: : :::..::: XP_016 KNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGF 300 310 320 330 340 350 310 320 pF1KB9 REAGSTSDSPSSPEFFL :: ::.::.:::::::. XP_016 RENGSSSDNPSSPEFFMYPRESSTSVM 360 370 380 >>XP_016878723 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 1072 init1: 642 opt: 707 Z-score: 472.6 bits: 95.9 E(85289): 1.4e-19 Smith-Waterman score: 1060; 52.6% identity (70.2% similar) in 359 aa overlap (18-323:19-373) 10 20 30 40 50 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTP :::::::::.::.:::::. ...: : :: .::.:::: XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPV-ETDRIISQCGRLIAGGSLSSTP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LSTPCSSVPSSPSFS-PT-----EQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIG .:::::::: ::::: :. :::.:::: :::.. ::.:::::...:::::::::. XP_016 MSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALIS 60 70 80 90 100 110 120 130 140 150 pF1KB9 -SHPVPQPLQSFDSF-RGAHHHHHHHHPHPHHAYPGAG-----------------VAHDE :: : .::.. :::.. . :.: .:.. XP_016 NSH---QLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSG 120 130 140 150 160 170 160 170 180 190 200 pF1KB9 LGPHAHPHHHH-----HHQASPPPSSAASPAQQLP-TSHPGPGPHATASATAAGGNGS-- ::: : :::: :: .. :..:.: : . .. : : :.:.. ..::.:. XP_016 AGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGG 180 190 200 210 220 230 210 220 230 240 pF1KB9 --------------------VEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTL .:::::.:::.::::::::.::: .:.:::::::::::: XP_016 GGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTL 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 KNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGF ::::::::::.:::::.: ::.::.::.:::..::::.:::.::::::: : :::..::: XP_016 KNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGF 300 310 320 330 340 350 310 320 pF1KB9 REAGSTSDSPSSPEFFL :: ::.::.:::::::. XP_016 RENGSSSDNPSSPEFFMYPRESSTSVM 360 370 380 >>NP_005351 (OMIM: 177075,601088,610202) transcription f (403 aa) initn: 1071 init1: 641 opt: 706 Z-score: 471.7 bits: 95.8 E(85289): 1.6e-19 Smith-Waterman score: 1059; 52.6% identity (70.2% similar) in 359 aa overlap (18-323:19-373) 10 20 30 40 50 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTP :::::::::.::.:::::. ...: : :: .::.:::: NP_005 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPV-ETDRIISQCGRLIAGGSLSSTP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LSTPCSSVPSSPSFS-PT-----EQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIG .:::::::: ::::: :. :::.:::: :::.. ::.:::::...:::::::::. NP_005 MSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALIS 60 70 80 90 100 110 120 130 140 150 pF1KB9 -SHPVPQPLQSFDSF-RGAHHHHHHHHPHPHHAYPGAG-----------------VAHDE :: : .::.. :::.. . :.: .:.. NP_005 NSH---QLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSG 120 130 140 150 160 170 160 170 180 190 200 pF1KB9 LGPHAHPHHHH-----HHQASPPPSSAASPAQQLP-TSHPGPGPHATASATAAGGNGS-- ::: : :::: :: .. :..:.: : . .. : : :.:.. ..::.:. NP_005 AGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGG 180 190 200 210 220 230 210 220 230 240 pF1KB9 --------------------VEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTL .:::::.:::.::::::::.::: .:.:::::::::::: NP_005 GGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTL 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 KNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGF ::::::::::.:::::.: ::.::.::.:::..::::.:::.::::::: : :::..::: NP_005 KNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGF 300 310 320 330 340 350 310 320 pF1KB9 REAGSTSDSPSSPEFFL :: ::.::.:::::::. NP_005 RENGSSSDNPSSPEFFITEPTRKLEPSVGYATFWKPQHRVLTSVFTK 360 370 380 390 400 >>NP_963883 (OMIM: 610303) transcription factor MafA [Ho (353 aa) initn: 931 init1: 510 opt: 581 Z-score: 392.2 bits: 81.0 E(85289): 4.1e-15 Smith-Waterman score: 995; 53.4% identity (64.0% similar) in 367 aa overlap (1-319:1-335) 10 20 30 40 50 60 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL :::::.:: :::.::::.::::::::.::.::::: .::: : :: : ::.::::: NP_963 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEP-PEAER---FCHRLPP-GSLSSTPL 10 20 30 40 50 70 80 pF1KB9 STPCSSVPSSPSF---SP---------------------------------TEQKTHLED ::::::::::::: :: : : ::: NP_963 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB9 LYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQPLQSFDSFRGAHHHHHH--HHPHPH ::::.. ...::::::::::::::::::: .:: :: ::: NP_963 LYWMSGYQHHLNPEALNLTPEDAVEALIGS---------------GHHGAHHGAHHPAAA 120 130 140 150 160 150 160 170 180 190 pF1KB9 HAY-----PG--AGVAHDELGP-HAHPHHH--HHHQASPPPSSAASPAQQLPTSHPGPGP :: :: .: . :..: : : :: :::.: : .. : : : NP_963 AAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHA-------AHHHHHHHHHHGGAG- 170 180 190 200 210 200 210 220 230 240 250 pF1KB9 HATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYA :. .:: . .:.:::::::::::::::::.::::.:.:::::::::::::::::: NP_963 HGG----GAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYA 220 230 240 250 260 260 270 280 290 300 310 pF1KB9 QSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGST ::::.:::::.: ::.:: :: .:::::: ::.:::.::: :: : ::::. : ... NP_963 QSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGG 270 280 290 300 310 320 320 pF1KB9 SDSPSSPEFFL . : : NP_963 AGFPREPSPPQAGPGGAKGTADFFL 330 340 350 >>XP_011535108 (OMIM: 162080,613750) PREDICTED: neural r (234 aa) initn: 530 init1: 423 opt: 442 Z-score: 305.4 bits: 64.3 E(85289): 2.8e-10 Smith-Waterman score: 442; 45.0% identity (67.8% similar) in 180 aa overlap (128-305:52-223) 100 110 120 130 140 150 pF1KB9 EALNLTPEDAVEALIGSHPVPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGA-GVAHDELG ::: : .: : : . :... . XP_011 RDRAVRGERGREGEVQAETRSTGRLPSQETRGAGGWTHSSRPCPPPPRMGNLAEAESRRA 30 40 50 60 70 80 160 170 180 190 200 210 pF1KB9 PHAHPHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHATASATAAG-GNGSVEDRFSDDQ : : :. . .... :: : . :: :.: : .. . . .:::: XP_011 PLAAPRGRAQRKVH---SSQPSSRMALP-----PSPLAMEYVNDFDLMKFELAERFSDAA 90 100 110 120 130 220 230 240 250 260 270 pF1KB9 LVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQ :::::::::::.::: .::..::::.:::::::::::.:: ::.::.. :: :...: XP_011 LVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAA 140 150 160 170 180 190 280 290 300 310 320 pF1KB9 QVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSDSPSSPEFFL :.. :. ::.::::::: ::..:..:..:: XP_011 QLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL 200 210 220 230 >>NP_006168 (OMIM: 162080,613750) neural retina-specific (237 aa) initn: 782 init1: 423 opt: 439 Z-score: 303.4 bits: 64.0 E(85289): 3.7e-10 Smith-Waterman score: 634; 43.9% identity (59.1% similar) in 303 aa overlap (11-305:3-226) 10 20 30 40 50 60 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL :: :::::::::::::.::.::.:: ::: : . : :: NP_006 MALPPSPLAMEYVNDFDLMKFEVKREP--SEGRPGPPTASL---GS------ 10 20 30 40 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFS-P-----TE-QKTHLEDLYWMASNYQQMNP-EALNLTPEDAVEALI :: :::: ::.:: : :: . ::.:::.:. ::.. :::.:.::.:.: : NP_006 -TPYSSVPPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 GSHPVPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPP :. ::: :. :: :::. : NP_006 GQGPVP-----VDG--------------PHGYYPGS-----------------------P 110 180 190 200 210 220 230 pF1KB9 PSSAASPAQQLPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFT ..:. .: . .:::: :::::::::::.::: NP_006 EETGAQHVQ-------------------------LAERFSDAALVSMSVRELNRQLRGCG 120 130 140 150 240 250 260 270 280 290 pF1KB9 KDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERD .::..::::.:::::::::::.:: ::.::.. :: :...: :.. :. ::.::::::: NP_006 RDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERD 160 170 180 190 200 210 300 310 320 pF1KB9 AYKVKCEKLANSGFREAGSTSDSPSSPEFFL ::..:..:..:: NP_006 LYKARCDRLTSSGPGSGDPSHLFL 220 230 >>XP_005267766 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 782 init1: 423 opt: 439 Z-score: 303.4 bits: 64.0 E(85289): 3.7e-10 Smith-Waterman score: 634; 43.9% identity (59.1% similar) in 303 aa overlap (11-305:3-226) 10 20 30 40 50 60 pF1KB9 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL :: :::::::::::::.::.::.:: ::: : . : :: XP_005 MALPPSPLAMEYVNDFDLMKFEVKREP--SEGRPGPPTASL---GS------ 10 20 30 40 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFS-P-----TE-QKTHLEDLYWMASNYQQMNP-EALNLTPEDAVEALI :: :::: ::.:: : :: . ::.:::.:. ::.. :::.:.::.:.: : XP_005 -TPYSSVPPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 GSHPVPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPP :. ::: :. :: :::. : XP_005 GQGPVP-----VDG--------------PHGYYPGS-----------------------P 110 180 190 200 210 220 230 pF1KB9 PSSAASPAQQLPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFT ..:. .: . .:::: :::::::::::.::: XP_005 EETGAQHVQ-------------------------LAERFSDAALVSMSVRELNRQLRGCG 120 130 140 150 240 250 260 270 280 290 pF1KB9 KDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERD .::..::::.:::::::::::.:: ::.::.. :: :...: :.. :. ::.::::::: XP_005 RDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERD 160 170 180 190 200 210 300 310 320 pF1KB9 AYKVKCEKLANSGFREAGSTSDSPSSPEFFL ::..:..:..:: XP_005 LYKARCDRLTSSGPGSGDPSHLFL 220 230 323 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:00:23 2016 done: Fri Nov 4 18:00:25 2016 Total Scan time: 9.230 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]