FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9678, 108 aa 1>>>pF1KB9678 108 - 108 aa - 108 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7574+/-0.000243; mu= 13.7171+/- 0.015 mean_var=70.2548+/-14.768, 0's: 0 Z-trim(122.7): 70 B-trim: 2075 in 1/56 Lambda= 0.153016 statistics sampled from 41285 (41369) to 41285 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.841), E-opt: 0.2 (0.485), width: 16 Scan time: 4.890 The best scores are: opt bits E(85289) NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 727 167.9 2.8e-42 NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172) 346 84.0 8.2e-17 XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172) 346 84.0 8.2e-17 NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331) 346 84.3 1.3e-16 XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331) 346 84.3 1.3e-16 XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331) 346 84.3 1.3e-16 NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331) 346 84.3 1.3e-16 XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 346 84.3 1.3e-16 NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331) 346 84.3 1.3e-16 XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 330 80.5 1.1e-15 NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 330 80.7 1.3e-15 XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 330 80.7 1.4e-15 XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351) 330 80.8 1.6e-15 XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 209 53.8 1.2e-07 NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 209 53.8 1.2e-07 NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 207 53.3 1.3e-07 NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 207 53.3 1.3e-07 NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 206 53.4 2.6e-07 NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 196 50.9 8.4e-07 NP_005589 (OMIM: 162360) helix-loop-helix protein ( 133) 194 50.3 8.5e-07 NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135) 194 50.4 8.6e-07 NP_005590 (OMIM: 162361) helix-loop-helix protein ( 135) 194 50.4 8.6e-07 NP_660161 (OMIM: 609875) protein atonal homolog 7 ( 152) 186 48.6 3.2e-06 NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 186 48.8 4.1e-06 XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 184 48.3 5.3e-06 NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 184 48.3 5.3e-06 NP_076924 (OMIM: 606624) neurogenin-2 [Homo sapien ( 272) 185 48.6 5.7e-06 NP_006152 (OMIM: 601726) neurogenin-1 [Homo sapien ( 237) 182 47.9 8.2e-06 XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 177 46.8 1.6e-05 NP_004812 (OMIM: 602406) heart- and neural crest d ( 215) 177 46.8 1.6e-05 NP_005163 (OMIM: 601461) protein atonal homolog 1 ( 354) 169 45.2 8e-05 NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214) 162 43.5 0.00016 XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214) 162 43.5 0.00016 NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 161 43.2 0.00017 NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179) 155 41.9 0.00041 NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179) 155 41.9 0.00041 NP_065697 (OMIM: 609154) achaete-scute homolog 3 [ ( 181) 154 41.6 0.00049 NP_982260 (OMIM: 609155) achaete-scute homolog 4 [ ( 173) 153 41.4 0.00055 NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 153 41.5 0.00062 NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193) 152 41.2 0.00069 NP_002491 (OMIM: 125853,601724,606394) neurogenic ( 356) 153 41.7 0.00093 NP_067014 (OMIM: 611635) neurogenic differentiatio ( 331) 151 41.2 0.0012 NP_006151 (OMIM: 601725) neurogenic differentiatio ( 382) 150 41.0 0.0015 NP_073565 (OMIM: 611513) neurogenic differentiatio ( 337) 148 40.6 0.0019 NP_004307 (OMIM: 100790,209880) achaete-scute homo ( 236) 144 39.5 0.0027 >>NP_005412 (OMIM: 186855,613065) T-cell acute lymphocyt (108 aa) initn: 727 init1: 727 opt: 727 Z-score: 880.1 bits: 167.9 E(85289): 2.8e-42 Smith-Waterman score: 727; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGE 10 20 30 40 50 60 70 80 90 100 pF1KB9 QSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLENYQVPSPGPSHHIP :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLENYQVPSPGPSHHIP 70 80 90 100 >>NP_001277335 (OMIM: 187040,613065) T-cell acute lympho (172 aa) initn: 329 init1: 329 opt: 346 Z-score: 422.9 bits: 84.0 E(85289): 8.2e-17 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:27-98) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPP ..:.::::.::::::::::.:::.:::::::::: NP_001 MFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLE :::::::: :::::.:::::.:.:..: . : : : NP_001 DKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDD 70 80 90 100 110 120 100 pF1KB9 NYQVPSPGPSHHIP NP_001 LLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 130 140 150 160 170 >>XP_016857682 (OMIM: 187040,613065) PREDICTED: T-cell a (172 aa) initn: 329 init1: 329 opt: 346 Z-score: 422.9 bits: 84.0 E(85289): 8.2e-17 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:27-98) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPP ..:.::::.::::::::::.:::.:::::::::: XP_016 MFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLE :::::::: :::::.:::::.:.:..: . : : : XP_016 DKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDD 70 80 90 100 110 120 100 pF1KB9 NYQVPSPGPSHHIP XP_016 LLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 130 140 150 160 170 >>NP_001277333 (OMIM: 187040,613065) T-cell acute lympho (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: NP_001 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : NP_001 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP NP_001 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>XP_016857677 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: XP_016 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : XP_016 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP XP_016 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>XP_016857676 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: XP_016 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : XP_016 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP XP_016 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>XP_016857679 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: XP_016 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : XP_016 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP XP_016 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>XP_016857678 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: XP_016 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : XP_016 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP XP_016 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>NP_003180 (OMIM: 187040,613065) T-cell acute lymphocyt (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: NP_003 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : NP_003 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP NP_003 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 >>XP_005271217 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa) initn: 329 init1: 329 opt: 346 Z-score: 419.1 bits: 84.3 E(85289): 1.3e-16 Smith-Waterman score: 346; 72.2% identity (88.9% similar) in 72 aa overlap (1-72:186-257) 10 20 30 pF1KB9 MTRKIFTNTRERWRQQNVNSAFAKLRKLIP ..:.::::.::::::::::.:::.:::::: XP_005 DAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIP 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB9 THPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDR :::::::::::: :::::.:::::.:.:..: . : : : XP_005 THPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGA 220 230 240 250 260 270 100 pF1KB9 TLLENYQVPSPGPSHHIP XP_005 PPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR 280 290 300 310 320 330 108 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:15:32 2016 done: Fri Nov 4 18:15:32 2016 Total Scan time: 4.890 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]