FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9681, 140 aa 1>>>pF1KB9681 140 - 140 aa - 140 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4426+/-0.000354; mu= 15.5453+/- 0.022 mean_var=51.3980+/-10.256, 0's: 0 Z-trim(111.8): 23 B-trim: 0 in 0/53 Lambda= 0.178896 statistics sampled from 20545 (20568) to 20545 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.241), width: 16 Scan time: 4.190 The best scores are: opt bits E(85289) XP_011543867 (OMIM: 300202,313400) PREDICTED: traf ( 140) 960 255.2 2.5e-68 NP_001011658 (OMIM: 300202,313400) trafficking pro ( 140) 960 255.2 2.5e-68 NP_055378 (OMIM: 300202,313400) trafficking protei ( 140) 960 255.2 2.5e-68 XP_011543868 (OMIM: 300202,313400) PREDICTED: traf ( 140) 960 255.2 2.5e-68 NP_001122307 (OMIM: 300202,313400) trafficking pro ( 174) 960 255.3 2.9e-68 NP_001305418 (OMIM: 610971) trafficking protein pa ( 165) 131 41.3 0.00072 NP_001305421 (OMIM: 610971) trafficking protein pa ( 114) 128 40.4 0.00091 NP_001305419 (OMIM: 610971) trafficking protein pa ( 176) 128 40.6 0.0013 NP_057230 (OMIM: 610971) trafficking protein parti ( 219) 128 40.6 0.0015 NP_001305415 (OMIM: 610971) trafficking protein pa ( 113) 125 39.7 0.0015 NP_001305423 (OMIM: 610971) trafficking protein pa ( 126) 125 39.7 0.0017 NP_001305459 (OMIM: 610970) trafficking protein pa ( 109) 123 39.1 0.0022 NP_001305454 (OMIM: 610970) trafficking protein pa ( 139) 123 39.2 0.0026 NP_001305457 (OMIM: 610970) trafficking protein pa ( 110) 117 37.6 0.0063 NP_057293 (OMIM: 610970) trafficking protein parti ( 140) 117 37.7 0.0077 >>XP_011543867 (OMIM: 300202,313400) PREDICTED: traffick (140 aa) initn: 960 init1: 960 opt: 960 Z-score: 1347.8 bits: 255.2 E(85289): 2.5e-68 Smith-Waterman score: 960; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB9 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP 70 80 90 100 110 120 130 140 pF1KB9 IRSSAFDRKVQFLGKKHLLS :::::::::::::::::::: XP_011 IRSSAFDRKVQFLGKKHLLS 130 140 >>NP_001011658 (OMIM: 300202,313400) trafficking protein (140 aa) initn: 960 init1: 960 opt: 960 Z-score: 1347.8 bits: 255.2 E(85289): 2.5e-68 Smith-Waterman score: 960; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB9 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP 70 80 90 100 110 120 130 140 pF1KB9 IRSSAFDRKVQFLGKKHLLS :::::::::::::::::::: NP_001 IRSSAFDRKVQFLGKKHLLS 130 140 >>NP_055378 (OMIM: 300202,313400) trafficking protein pa (140 aa) initn: 960 init1: 960 opt: 960 Z-score: 1347.8 bits: 255.2 E(85289): 2.5e-68 Smith-Waterman score: 960; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB9 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP 70 80 90 100 110 120 130 140 pF1KB9 IRSSAFDRKVQFLGKKHLLS :::::::::::::::::::: NP_055 IRSSAFDRKVQFLGKKHLLS 130 140 >>XP_011543868 (OMIM: 300202,313400) PREDICTED: traffick (140 aa) initn: 960 init1: 960 opt: 960 Z-score: 1347.8 bits: 255.2 E(85289): 2.5e-68 Smith-Waterman score: 960; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB9 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSP 70 80 90 100 110 120 130 140 pF1KB9 IRSSAFDRKVQFLGKKHLLS :::::::::::::::::::: XP_011 IRSSAFDRKVQFLGKKHLLS 130 140 >>NP_001122307 (OMIM: 300202,313400) trafficking protein (174 aa) initn: 960 init1: 960 opt: 960 Z-score: 1346.5 bits: 255.3 E(85289): 2.9e-68 Smith-Waterman score: 960; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:35-174) 10 20 30 pF1KB9 MSGSFYFVIVGHHDNPVFEMEFLPAGKAES :::::::::::::::::::::::::::::: NP_001 KQDRSGLRSTELNVLEYQPLCAVRSHILKTMSGSFYFVIVGHHDNPVFEMEFLPAGKAES 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 KDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIR 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 QEDGIKNFFTDVYDLYIKFSMNPFYEPNSPIRSSAFDRKVQFLGKKHLLS :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEDGIKNFFTDVYDLYIKFSMNPFYEPNSPIRSSAFDRKVQFLGKKHLLS 130 140 150 160 170 >>NP_001305418 (OMIM: 610971) trafficking protein partic (165 aa) initn: 96 init1: 65 opt: 131 Z-score: 190.5 bits: 41.3 E(85289): 0.00072 Smith-Waterman score: 131; 28.1% identity (61.5% similar) in 96 aa overlap (41-132:59-150) 20 30 40 50 60 pF1KB9 GHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDL--VDEN-MWLSNNMYLKTVDKF ..::.: . .: : . ... . .: : NP_001 EKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGRYTADGKEMLETDTF 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB9 NEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSM-NPFYEPNSPIRSSAF . . . : ..:..: : :: :: ... .:..: :.. :::: . ::: : NP_001 K---LHCYQTLTGIKFVVLADPRQA-GIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELF 90 100 110 120 130 140 130 140 pF1KB9 DRKVQFLGKKHLLS :..... NP_001 DQNLKLALEVAEKAGTFGPGS 150 160 >>NP_001305421 (OMIM: 610971) trafficking protein partic (114 aa) initn: 84 init1: 65 opt: 128 Z-score: 188.6 bits: 40.4 E(85289): 0.00091 Smith-Waterman score: 128; 29.5% identity (62.8% similar) in 78 aa overlap (56-132:26-99) 30 40 50 60 70 80 pF1KB9 GKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIM :... . .: :. . . : ..:.. NP_001 MKNATDPDLDFRLFAIGSQLSPEQGSSGIEMLETDTFK---LHCYQTLTGIKFVV 10 20 30 40 50 90 100 110 120 130 140 pF1KB9 LHDIRQEDGIKNFFTDVYDLYIKFSM-NPFYEPNSPIRSSAFDRKVQFLGKKHLLS : : :: :: ... .:..: :.. :::: . ::: ::..... NP_001 LADPRQA-GIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFG 60 70 80 90 100 110 NP_001 PGS >>NP_001305419 (OMIM: 610971) trafficking protein partic (176 aa) initn: 96 init1: 65 opt: 128 Z-score: 185.9 bits: 40.6 E(85289): 0.0013 Smith-Waterman score: 128; 29.5% identity (62.8% similar) in 78 aa overlap (56-132:88-161) 30 40 50 60 70 80 pF1KB9 GKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIM :... . .: :. . . : ..:.. NP_001 RVGHAVLAINGMDVNGRLFAIGSQLSPEQGSSGIEMLETDTFK---LHCYQTLTGIKFVV 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB9 LHDIRQEDGIKNFFTDVYDLYIKFSM-NPFYEPNSPIRSSAFDRKVQFLGKKHLLS : : :: :: ... .:..: :.. :::: . ::: ::..... NP_001 LADPRQA-GIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFG 120 130 140 150 160 170 NP_001 PGS >>NP_057230 (OMIM: 610971) trafficking protein particle (219 aa) initn: 84 init1: 65 opt: 128 Z-score: 184.6 bits: 40.6 E(85289): 0.0015 Smith-Waterman score: 128; 29.5% identity (62.8% similar) in 78 aa overlap (56-132:131-204) 30 40 50 60 70 80 pF1KB9 GKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIM :... . .: :. . . : ..:.. NP_057 PRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFK---LHCYQTLTGIKFVV 110 120 130 140 150 90 100 110 120 130 140 pF1KB9 LHDIRQEDGIKNFFTDVYDLYIKFSM-NPFYEPNSPIRSSAFDRKVQFLGKKHLLS : : :: :: ... .:..: :.. :::: . ::: ::..... NP_057 LADPRQA-GIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFG 160 170 180 190 200 210 NP_057 PGS >>NP_001305415 (OMIM: 610971) trafficking protein partic (113 aa) initn: 79 init1: 65 opt: 125 Z-score: 184.5 bits: 39.7 E(85289): 0.0015 Smith-Waterman score: 125; 35.8% identity (69.8% similar) in 53 aa overlap (81-132:47-98) 60 70 80 90 100 110 pF1KB9 ENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFS ..:..: : :: :: ... .:..: :. NP_001 TLLITRCPFDLAGPASLLMRSLCWPPCSTRIKFVVLADPRQA-GIDSLLRKIYEIYSDFA 20 30 40 50 60 70 120 130 140 pF1KB9 M-NPFYEPNSPIRSSAFDRKVQFLGKKHLLS . :::: . ::: ::..... NP_001 LKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS 80 90 100 110 140 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:17:12 2016 done: Fri Nov 4 18:17:13 2016 Total Scan time: 4.190 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]