FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9682, 149 aa
1>>>pF1KB9682 149 - 149 aa - 149 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1713+/-0.000279; mu= 13.1846+/- 0.018
mean_var=68.5090+/-13.902, 0's: 0 Z-trim(118.4): 43 B-trim: 16 in 1/54
Lambda= 0.154953
statistics sampled from 31300 (31343) to 31300 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.367), width: 16
Scan time: 5.390
The best scores are: opt bits E(85289)
NP_851998 (OMIM: 600349) DNA-binding protein inhib ( 149) 950 220.4 8.8e-58
NP_002156 (OMIM: 600349) DNA-binding protein inhib ( 155) 903 209.9 1.3e-54
NP_002157 (OMIM: 600386) DNA-binding protein inhib ( 134) 286 71.9 3.9e-13
NP_002158 (OMIM: 600277) DNA-binding protein inhib ( 119) 275 69.4 1.9e-12
NP_001537 (OMIM: 600581) DNA-binding protein inhib ( 161) 257 65.5 4e-11
NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193) 135 38.2 0.0076
>>NP_851998 (OMIM: 600349) DNA-binding protein inhibitor (149 aa)
initn: 950 init1: 950 opt: 950 Z-score: 1158.4 bits: 220.4 E(85289): 8.8e-58
Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KB9 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG
70 80 90 100 110 120
130 140
pF1KB9 RGLPVRAPLSTLNGEISALTAEVRSRSDH
:::::::::::::::::::::::::::::
NP_851 RGLPVRAPLSTLNGEISALTAEVRSRSDH
130 140
>>NP_002156 (OMIM: 600349) DNA-binding protein inhibitor (155 aa)
initn: 903 init1: 903 opt: 903 Z-score: 1101.3 bits: 209.9 E(85289): 1.3e-54
Smith-Waterman score: 903; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KB9 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG
70 80 90 100 110 120
130 140
pF1KB9 RGLPVRAPLSTLNGEISALTAEVRSRSDH
::::::::::::::::::::::
NP_002 RGLPVRAPLSTLNGEISALTAEAACVPADDRILCR
130 140 150
>>NP_002157 (OMIM: 600386) DNA-binding protein inhibitor (134 aa)
initn: 307 init1: 249 opt: 286 Z-score: 356.8 bits: 71.9 E(85289): 3.9e-13
Smith-Waterman score: 293; 49.5% identity (73.0% similar) in 111 aa overlap (35-140:15-114)
10 20 30 40 50 60
pF1KB9 SGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNV
::..:..::: .. : .:. .
NP_002 MKAFSPVRSVRKNSLSDHSLGISR------SKTP--VDDPM--S
10 20 30
70 80 90 100 110
pF1KB9 LLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGT-----PG
:::.:: :::.::::::..:::.::::.:::::::::: :::. :.:. . . ::
NP_002 LLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPG
40 50 60 70 80 90
120 130 140
pF1KB9 GRGLPVRAPLSTLNGEISALTAEVRSRSDH
.. :.::.::: .:: :.
NP_002 -QNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG
100 110 120 130
>>NP_002158 (OMIM: 600277) DNA-binding protein inhibitor (119 aa)
initn: 248 init1: 192 opt: 275 Z-score: 344.3 bits: 69.4 E(85289): 1.9e-12
Smith-Waterman score: 276; 49.1% identity (69.1% similar) in 110 aa overlap (19-126:1-100)
10 20 30 40 50
pF1KB9 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAG-GAGARLP-ALLD
.:: . . : :.: ::::.:.::.: : : .:. : .:::
NP_002 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLD
10 20 30 40
60 70 80 90 100 110
pF1KB9 EQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTP
::: :::::.:::: .:.. ..:.:::::.::::: :::. : .: : :
NP_002 ---------DMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPGPP
50 60 70 80 90
120 130 140
pF1KB9 GGRGLPVRAPLSTLNGEISALTAEVRSRSDH
: ::..
NP_002 DGPHLPIQTAELTPELVISNDKRSFCH
100 110
>>NP_001537 (OMIM: 600581) DNA-binding protein inhibitor (161 aa)
initn: 300 init1: 227 opt: 257 Z-score: 320.6 bits: 65.5 E(85289): 4e-11
Smith-Waterman score: 266; 42.5% identity (64.9% similar) in 134 aa overlap (20-133:12-144)
10 20 30 40 50
pF1KB9 MKVASGSTATAAAGPSCALKAGKTASGAGEV-VRCLSEQSVAI----SRCAGGAGARLPA
. . .. :.::. .:::.:.. .. . :..:.:: :
NP_001 MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKA
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 L---LDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSE
:: . : ::: :::::..::::.: :.::::::::::::::: :::: :...
NP_001 AEAAADEPAL-CLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETH
60 70 80 90 100 110
120 130 140
pF1KB9 SEV----------GTPGGR--GLPVRAPLSTLNGEISALTAEVRSRSDH
. :.: . : :.::..::
NP_001 PALLRQPPPPAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILCR
120 130 140 150 160
>>NP_005161 (OMIM: 601886) achaete-scute homolog 2 [Homo (193 aa)
initn: 128 init1: 91 opt: 135 Z-score: 172.1 bits: 38.2 E(85289): 0.0076
Smith-Waterman score: 135; 31.8% identity (59.1% similar) in 132 aa overlap (6-128:3-130)
10 20 30 40 50
pF1KB9 MKVASGSTATAAAGPSCALKAGKTAS---GAGEVVRCLSEQSVAISRCAGGAGARLPALL
:.: .: :. . .: .: .. :..:: .. : .. .:::.: :
NP_005 MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCSRRRRPATAETGGGAAAV--ARR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 DEQQVN-VLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEV-
.:.. : : : ... .. :.. :: ..:.:::: :. ...::: :: : .. :
NP_005 NERERNRVKLVNLG--FQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVR
60 70 80 90 100 110
120 130 140
pF1KB9 -GTPGG-RGLPVR--APLSTLNGEISALTAEVRSRSDH
. :: : :: ::
NP_005 NALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGSSEPGSPRSAYSSDDSGCE
120 130 140 150 160 170
149 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:17:44 2016 done: Fri Nov 4 18:17:45 2016
Total Scan time: 5.390 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]