FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9684, 164 aa 1>>>pF1KB9684 164 - 164 aa - 164 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3757+/-0.000303; mu= 12.1263+/- 0.019 mean_var=71.9585+/-13.834, 0's: 0 Z-trim(117.7): 199 B-trim: 205 in 3/54 Lambda= 0.151194 statistics sampled from 29766 (29965) to 29766 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.351), width: 16 Scan time: 5.520 The best scores are: opt bits E(85289) NP_689908 (OMIM: 300627) zinc finger protein 449 [ ( 518) 815 186.5 5.2e-47 XP_011529614 (OMIM: 300627) PREDICTED: zinc finger ( 518) 815 186.5 5.2e-47 XP_011520954 (OMIM: 608387) PREDICTED: zinc finger ( 285) 437 103.9 2.1e-22 NP_004211 (OMIM: 608387) zinc finger protein 213 [ ( 459) 437 104.0 3.1e-22 NP_001128127 (OMIM: 608387) zinc finger protein 21 ( 459) 437 104.0 3.1e-22 NP_001309220 (OMIM: 609600) zinc finger protein 39 ( 210) 431 102.5 4.1e-22 XP_016868074 (OMIM: 601261) PREDICTED: zinc finger ( 450) 435 103.6 4.1e-22 XP_005250625 (OMIM: 601261) PREDICTED: zinc finger ( 473) 435 103.6 4.3e-22 XP_006716176 (OMIM: 601261) PREDICTED: zinc finger ( 473) 435 103.6 4.3e-22 NP_666019 (OMIM: 601261) zinc finger and SCAN doma ( 473) 435 103.6 4.3e-22 XP_016868073 (OMIM: 601261) PREDICTED: zinc finger ( 473) 435 103.6 4.3e-22 XP_016881178 (OMIM: 609600) PREDICTED: zinc finger ( 266) 431 102.6 4.9e-22 NP_665699 (OMIM: 609600) zinc finger protein 396 i ( 333) 431 102.6 5.9e-22 NP_001309219 (OMIM: 609600) zinc finger protein 39 ( 335) 431 102.6 5.9e-22 XP_006722495 (OMIM: 609600) PREDICTED: zinc finger ( 335) 431 102.6 5.9e-22 NP_001309215 (OMIM: 609600) zinc finger protein 39 ( 335) 431 102.6 5.9e-22 XP_016881176 (OMIM: 609600) PREDICTED: zinc finger ( 335) 431 102.6 5.9e-22 XP_016881177 (OMIM: 609600) PREDICTED: zinc finger ( 335) 431 102.6 5.9e-22 XP_016867413 (OMIM: 611272) PREDICTED: zinc finger ( 766) 433 103.3 8.6e-22 XP_016867412 (OMIM: 611272) PREDICTED: zinc finger ( 766) 433 103.3 8.6e-22 NP_001305012 (OMIM: 611272) zinc finger protein wi ( 766) 433 103.3 8.6e-22 XP_016867411 (OMIM: 611272) PREDICTED: zinc finger ( 838) 433 103.3 9.3e-22 XP_016867410 (OMIM: 611272) PREDICTED: zinc finger ( 838) 433 103.3 9.3e-22 XP_016867409 (OMIM: 611272) PREDICTED: zinc finger ( 838) 433 103.3 9.3e-22 NP_055384 (OMIM: 611272) zinc finger protein with ( 839) 433 103.3 9.3e-22 NP_001305011 (OMIM: 611272) zinc finger protein wi ( 839) 433 103.3 9.3e-22 XP_016867408 (OMIM: 611272) PREDICTED: zinc finger ( 839) 433 103.3 9.3e-22 NP_659570 (OMIM: 611272) zinc finger protein with ( 839) 433 103.3 9.3e-22 XP_016867407 (OMIM: 611272) PREDICTED: zinc finger ( 839) 433 103.3 9.3e-22 XP_006710939 (OMIM: 611315) PREDICTED: zinc finger ( 989) 430 102.7 1.7e-21 XP_016857727 (OMIM: 611315) PREDICTED: zinc finger (1042) 430 102.7 1.7e-21 XP_005271228 (OMIM: 611315) PREDICTED: zinc finger (1042) 430 102.7 1.7e-21 XP_006710937 (OMIM: 611315) PREDICTED: zinc finger (1043) 430 102.7 1.7e-21 XP_016857726 (OMIM: 611315) PREDICTED: zinc finger (1043) 430 102.7 1.7e-21 NP_660281 (OMIM: 611315) zinc finger and SCAN doma (1043) 430 102.7 1.7e-21 NP_443155 (OMIM: 615254) SCAN domain-containing pr (1325) 427 102.1 3.3e-21 XP_011513319 (OMIM: 603978) PREDICTED: zinc finger ( 565) 410 98.2 2.2e-20 NP_001156863 (OMIM: 603978) zinc finger and SCAN d ( 611) 410 98.2 2.3e-20 XP_011513316 (OMIM: 603978) PREDICTED: zinc finger ( 611) 410 98.2 2.3e-20 XP_011513317 (OMIM: 603978) PREDICTED: zinc finger ( 611) 410 98.2 2.3e-20 XP_016867017 (OMIM: 603978) PREDICTED: zinc finger ( 611) 410 98.2 2.3e-20 NP_006290 (OMIM: 602246) zinc finger and SCAN doma ( 394) 404 96.8 4e-20 XP_016866756 (OMIM: 602246) PREDICTED: zinc finger ( 394) 404 96.8 4e-20 NP_001186409 (OMIM: 602246) zinc finger and SCAN d ( 394) 404 96.8 4e-20 NP_115723 (OMIM: 609601) zinc finger protein 397 i ( 275) 402 96.3 4.1e-20 NP_001186408 (OMIM: 602246) zinc finger and SCAN d ( 445) 404 96.8 4.4e-20 XP_011524531 (OMIM: 609601) PREDICTED: zinc finger ( 553) 405 97.1 4.6e-20 XP_006722621 (OMIM: 609601) PREDICTED: zinc finger ( 553) 405 97.1 4.6e-20 XP_011524532 (OMIM: 609601) PREDICTED: zinc finger ( 553) 405 97.1 4.6e-20 XP_011513180 (OMIM: 602246) PREDICTED: zinc finger ( 526) 404 96.9 5.1e-20 >>NP_689908 (OMIM: 300627) zinc finger protein 449 [Homo (518 aa) initn: 833 init1: 815 opt: 815 Z-score: 965.0 bits: 186.5 E(85289): 5.2e-47 Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 119 aa overlap (1-119:1-119) 10 20 30 40 50 60 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVD 70 80 90 100 110 120 130 140 150 160 pF1KB9 KECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC NP_689 MHDMLLEELAPVGTAHIPPTMHLESPALQVMGPAQEAPVAEAWIPQAGPPELNYGATGEC 130 140 150 160 170 180 >>XP_011529614 (OMIM: 300627) PREDICTED: zinc finger pro (518 aa) initn: 833 init1: 815 opt: 815 Z-score: 965.0 bits: 186.5 E(85289): 5.2e-47 Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 119 aa overlap (1-119:1-119) 10 20 30 40 50 60 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVD 70 80 90 100 110 120 130 140 150 160 pF1KB9 KECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC XP_011 MHDMLLEELAPVGTAHIPPTMHLESPALQVMGPAQEAPVAEAWIPQAGPPELNYGATGEC 130 140 150 160 170 180 >>XP_011520954 (OMIM: 608387) PREDICTED: zinc finger pro (285 aa) initn: 426 init1: 409 opt: 437 Z-score: 523.2 bits: 103.9 E(85289): 2.1e-22 Smith-Waterman score: 442; 47.7% identity (70.9% similar) in 151 aa overlap (11-152:26-170) 10 20 30 40 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPH .: .: :. .: : :. ::::::: : .. ::: XP_011 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 EAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLI :::..::::::.::.:..:.:::::::::::::::.:: ::. ::::. : . :..:.:. XP_011 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 110 120 130 140 150 pF1KB9 EDLQRE------LEIPEQQVRKEC---GIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSR ::::.. ..: .... : : . :: .. .: :: . :: : XP_011 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTV-GARRRPSV-----PQEQHSHS 130 140 150 160 170 160 pF1KB9 VLFLFLFC XP_011 AQPPALLKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKREN 180 190 200 210 220 230 >>NP_004211 (OMIM: 608387) zinc finger protein 213 [Homo (459 aa) initn: 409 init1: 409 opt: 437 Z-score: 520.2 bits: 104.0 E(85289): 3.1e-22 Smith-Waterman score: 442; 47.7% identity (70.9% similar) in 151 aa overlap (11-152:26-170) 10 20 30 40 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPH .: .: :. .: : :. ::::::: : .. ::: NP_004 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 EAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLI :::..::::::.::.:..:.:::::::::::::::.:: ::. ::::. : . :..:.:. NP_004 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 110 120 130 140 150 pF1KB9 EDLQRE------LEIPEQQVRKEC---GIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSR ::::.. ..: .... : : . :: .. .: :: . :: : NP_004 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTV-GARRRPSV-----PQEQHSHS 130 140 150 160 170 160 pF1KB9 VLFLFLFC NP_004 AQPPALLKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKREN 180 190 200 210 220 230 >>NP_001128127 (OMIM: 608387) zinc finger protein 213 [H (459 aa) initn: 409 init1: 409 opt: 437 Z-score: 520.2 bits: 104.0 E(85289): 3.1e-22 Smith-Waterman score: 442; 47.7% identity (70.9% similar) in 151 aa overlap (11-152:26-170) 10 20 30 40 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPH .: .: :. .: : :. ::::::: : .. ::: NP_001 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 EAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLI :::..::::::.::.:..:.:::::::::::::::.:: ::. ::::. : . :..:.:. NP_001 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 110 120 130 140 150 pF1KB9 EDLQRE------LEIPEQQVRKEC---GIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSR ::::.. ..: .... : : . :: .. .: :: . :: : NP_001 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTV-GARRRPSV-----PQEQHSHS 130 140 150 160 170 160 pF1KB9 VLFLFLFC NP_001 AQPPALLKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKREN 180 190 200 210 220 230 >>NP_001309220 (OMIM: 609600) zinc finger protein 396 is (210 aa) initn: 456 init1: 410 opt: 431 Z-score: 518.1 bits: 102.5 E(85289): 4.1e-22 Smith-Waterman score: 431; 48.5% identity (78.8% similar) in 132 aa overlap (7-135:34-160) 10 20 30 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQF : ..::. .: .. :.:::.:::: NP_001 KLGKSSSLLTQTSEECNGILTEKMEEEEQTCDPDSSLHWSSSYSP-----ETFRQQFRQF 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 QYREAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPE :... :::::...::::: ::.:....::::::::::::::.::: :...::..: :: NP_001 GYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKHHPE 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 NRERVVSLIEDLQRELEIPEQQV---RKECGIFVIGPKEVAEAAGTRPHICLYVIPQPQD : :..:...::..:::. :.: ::. ..:.:..: NP_001 NGEETVTMLEDVERELDGPKQIFFGRRKDMIAEKLAPSEITEELPSSQLMPVKKQLQGAS 120 130 140 150 160 170 160 pF1KB9 FSRVLFLFLFC NP_001 WELQSLRPHGEGAGFSSCWKVWGPSAHHTHLS 180 190 200 210 >>XP_016868074 (OMIM: 601261) PREDICTED: zinc finger and (450 aa) initn: 433 init1: 433 opt: 435 Z-score: 517.9 bits: 103.6 E(85289): 4.1e-22 Smith-Waterman score: 435; 60.6% identity (88.9% similar) in 99 aa overlap (21-119:36-134) 10 20 30 40 50 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNK .: . :.:::::::: :... ::.::... XP_016 LGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQR : :::.::.:....:::::::::::::::::: :...::.:::::. :..:.:.:::.: XP_016 LRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLER 70 80 90 100 110 120 120 130 140 150 160 pF1KB9 ELEIPEQQVRKECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC ::. : .:: XP_016 ELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGE 130 140 150 160 170 180 >>XP_005250625 (OMIM: 601261) PREDICTED: zinc finger and (473 aa) initn: 452 init1: 433 opt: 435 Z-score: 517.6 bits: 103.6 E(85289): 4.3e-22 Smith-Waterman score: 435; 60.6% identity (88.9% similar) in 99 aa overlap (21-119:36-134) 10 20 30 40 50 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNK .: . :.:::::::: :... ::.::... XP_005 LGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQR : :::.::.:....:::::::::::::::::: :...::.:::::. :..:.:.:::.: XP_005 LRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLER 70 80 90 100 110 120 120 130 140 150 160 pF1KB9 ELEIPEQQVRKECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC ::. : .:: XP_005 ELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGE 130 140 150 160 170 180 >>XP_006716176 (OMIM: 601261) PREDICTED: zinc finger and (473 aa) initn: 452 init1: 433 opt: 435 Z-score: 517.6 bits: 103.6 E(85289): 4.3e-22 Smith-Waterman score: 435; 60.6% identity (88.9% similar) in 99 aa overlap (21-119:36-134) 10 20 30 40 50 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNK .: . :.:::::::: :... ::.::... XP_006 LGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQR : :::.::.:....:::::::::::::::::: :...::.:::::. :..:.:.:::.: XP_006 LRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLER 70 80 90 100 110 120 120 130 140 150 160 pF1KB9 ELEIPEQQVRKECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC ::. : .:: XP_006 ELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGE 130 140 150 160 170 180 >>NP_666019 (OMIM: 601261) zinc finger and SCAN domain-c (473 aa) initn: 452 init1: 433 opt: 435 Z-score: 517.6 bits: 103.6 E(85289): 4.3e-22 Smith-Waterman score: 435; 60.6% identity (88.9% similar) in 99 aa overlap (21-119:36-134) 10 20 30 40 50 pF1KB9 MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNK .: . :.:::::::: :... ::.::... NP_666 LGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQR : :::.::.:....:::::::::::::::::: :...::.:::::. :..:.:.:::.: NP_666 LRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLER 70 80 90 100 110 120 120 130 140 150 160 pF1KB9 ELEIPEQQVRKECGIFVIGPKEVAEAAGTRPHICLYVIPQPQDFSRVLFLFLFC ::. : .:: NP_666 ELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGE 130 140 150 160 170 180 164 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:18:48 2016 done: Fri Nov 4 18:18:49 2016 Total Scan time: 5.520 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]