FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9688, 222 aa 1>>>pF1KB9688 222 - 222 aa - 222 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7420+/-0.000321; mu= 6.1506+/- 0.020 mean_var=204.7626+/-41.045, 0's: 0 Z-trim(123.5): 199 B-trim: 119 in 1/55 Lambda= 0.089629 statistics sampled from 43261 (43510) to 43261 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.51), width: 16 Scan time: 6.570 The best scores are: opt bits E(85289) NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 1530 209.0 5e-54 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 525 79.2 7.5e-15 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 524 79.0 8.3e-15 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 502 76.2 5.7e-14 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 458 70.5 3e-12 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 458 70.5 3e-12 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 456 70.2 3.5e-12 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 457 70.4 3.8e-12 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 422 65.8 6.8e-11 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 422 65.8 6.8e-11 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 422 65.8 6.8e-11 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 422 65.9 8.1e-11 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 413 64.4 1.2e-10 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 413 64.6 1.6e-10 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 413 64.6 1.6e-10 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 396 62.4 6.8e-10 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 391 61.8 1.1e-09 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 362 58.1 1.8e-08 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 357 57.5 2.7e-08 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 353 56.9 3.5e-08 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 353 56.9 3.5e-08 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 353 56.9 3.5e-08 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 349 56.4 5e-08 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 342 55.7 1.4e-07 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 342 55.7 1.4e-07 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 342 55.7 1.4e-07 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 342 55.7 1.4e-07 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 342 55.7 1.4e-07 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 342 55.7 1.4e-07 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 342 55.7 1.4e-07 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 333 54.3 2.1e-07 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 311 51.1 8.5e-07 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 317 52.3 9.8e-07 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 317 52.4 1.2e-06 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 315 52.2 1.6e-06 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 315 52.2 1.6e-06 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 312 51.7 1.8e-06 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 309 51.2 1.9e-06 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 312 51.8 2e-06 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 307 51.1 2.8e-06 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 307 51.1 2.9e-06 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 305 50.8 3e-06 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 305 50.8 3.4e-06 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 305 50.8 3.4e-06 >>NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [Homo (222 aa) initn: 1530 init1: 1530 opt: 1530 Z-score: 1090.9 bits: 209.0 E(85289): 5e-54 Smith-Waterman score: 1530; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 VDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYL 130 140 150 160 170 180 190 200 210 220 pF1KB9 TRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL :::::::::::::::::::::::::::::::::::::::::: NP_061 TRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL 190 200 210 220 >>NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [Homo (269 aa) initn: 521 init1: 404 opt: 525 Z-score: 387.6 bits: 79.2 E(85289): 7.5e-15 Smith-Waterman score: 553; 41.0% identity (60.5% similar) in 256 aa overlap (8-218:8-257) 10 20 30 40 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASR------------YCYGGLDLSIT :: . :: : :.. ::::.: ...: : :.:.:::.. NP_002 MSSYFVNSFSGRYPNGPDYQLL---NYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVN 10 20 30 40 50 50 60 70 80 90 pF1KB9 ------------------FPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRDE :: :: .. . .. . :. :. . . : : . NP_002 RSSASSSHFGAVGESSRAFPAPAQEPRFRQA-ASSCSLSSPESLPCTNGDSHGAKP--SA 60 70 80 90 100 110 100 110 120 130 pF1KB9 AAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAP------------P ..: . . ....: . ..:..:.: .: .: ..:. : : : NP_002 SSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTP 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB9 QIYPWMTKLHMSHET---DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLN ::.::: :::.::. ::::.::.::::::::::::::::::::::::::::. :::. NP_002 QIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 180 190 200 210 220 230 200 210 220 pF1KB9 ERQIKIWFQNRRMKWKKDSKMKSKEAL ::::::::::::::::::.:.:: NP_002 ERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP 240 250 260 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 523 init1: 410 opt: 524 Z-score: 386.8 bits: 79.0 E(85289): 8.3e-15 Smith-Waterman score: 589; 45.0% identity (65.7% similar) in 251 aa overlap (9-218:9-258) 10 20 30 40 50 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASE-------VQASRYCYG--GLDLSITFPP : . :: : :.... :...:.:: ....:: :: :.:::. NP_061 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 10 20 30 40 50 60 60 70 80 90 100 pF1KB9 PAPSNS-LHGVDMAANPRAHPDRPACSAAAAPGHAPGRDE-----AAPLNPGMYSQKAAR . .: .. ..::. : : .: : :. :.: : .:: .:: :..... NP_061 SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAP-SPGSDSHHGGK 70 80 90 100 110 110 120 130 140 pF1KB9 PAL------------------EERAKSSGEIKEEQAQTGQPAGLSQP-PAPP---QIYPW .: : . .:: .. :.. : .. :.: :::: ::::: NP_061 NSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPW 120 130 140 150 160 170 150 160 170 180 190 pF1KB9 MTKLHMSHET----DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQI : :::.::.. .:::.::.::::::::::::::::::::::::::::. :::.:::: NP_061 MRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQI 180 190 200 210 220 230 200 210 220 pF1KB9 KIWFQNRRMKWKKDSKMKSKEAL ::::::::::::::.:.:: NP_061 KIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 240 250 260 270 >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 513 init1: 366 opt: 502 Z-score: 371.8 bits: 76.2 E(85289): 5.7e-14 Smith-Waterman score: 502; 44.9% identity (64.4% similar) in 225 aa overlap (1-216:3-215) 10 20 30 40 50 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPA--PSN ::::..:: : . :..: . :.: . :.. : ::: . : ::. : NP_055 MVMSSYMVNSKYVD-PKFPPCEEYLQGGYLGE---QGADY-YGGGAQGADFQPPGLYPRP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 SLHGVDMAAN-PRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSS .. .... : :: . . :: .:: ::: .: . : :: :.. NP_055 DFGEQPFGGSGPGPGSALPARGHGQEPG-GPGGHYAAPGEP-CPAPPAPPPAPLPGARAY 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 GEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMS----HETDG--KRSRTSYTRYQTLE .. .: .: ..:.:: . .:::: :.:.. . : : :::::.::: :.:: NP_055 SQSDPKQPPSG--TALKQPAV---VYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLE 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 LEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL ::::::::::::::::::::..:::.:::::::::::::::::: :. NP_055 LEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSS 170 180 190 200 210 220 NP_055 SSCSSSVAPSQHLQPMAKDHHTDLTTL 230 240 250 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 494 init1: 360 opt: 458 Z-score: 340.8 bits: 70.5 E(85289): 3e-12 Smith-Waterman score: 468; 40.7% identity (57.7% similar) in 241 aa overlap (1-216:3-217) 10 20 30 40 50 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITF--------P ::::. .: : . :..: : .:.. : . : : : : NP_055 MIMSSYLMDSNYID-PKFPP-----CEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYP 10 20 30 40 50 60 70 80 90 100 pF1KB9 PPAPSNSLHGVDMAANPRAHPDRP-ACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALE :: : : .:.: .:.. .::.. :. .: . : . . .. .: NP_055 PPPPRPS------------YPERQYSCTSLQGPGNSRGH---GPAQAGHHHPEKSQ-SLC 60 70 80 90 110 120 130 140 150 pF1KB9 ERAKSSGEIKEEQAQTGQPAGLSQPPAP----------PQIYPWMTKLHMSH---ETDG- : : :: . . : . ::: :: : .:::: :.:.: . .: NP_055 EPAPLSGA---SASPSPAPPACSQP-APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGG 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB9 --KRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKD :::::.::: :.::::::::.:::::::::::::..:::.:::::::::::::::::: NP_055 EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKD 160 170 180 190 200 210 220 pF1KB9 SKMKSKEAL .. NP_055 HRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 220 230 240 250 260 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 494 init1: 360 opt: 458 Z-score: 340.8 bits: 70.5 E(85289): 3e-12 Smith-Waterman score: 468; 40.7% identity (57.7% similar) in 241 aa overlap (1-216:3-217) 10 20 30 40 50 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITF--------P ::::. .: : . :..: : .:.. : . : : : : NP_705 MIMSSYLMDSNYID-PKFPP-----CEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYP 10 20 30 40 50 60 70 80 90 100 pF1KB9 PPAPSNSLHGVDMAANPRAHPDRP-ACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALE :: : : .:.: .:.. .::.. :. .: . : . . .. .: NP_705 PPPPRPS------------YPERQYSCTSLQGPGNSRGH---GPAQAGHHHPEKSQ-SLC 60 70 80 90 110 120 130 140 150 pF1KB9 ERAKSSGEIKEEQAQTGQPAGLSQPPAP----------PQIYPWMTKLHMSH---ETDG- : : :: . . : . ::: :: : .:::: :.:.: . .: NP_705 EPAPLSGA---SASPSPAPPACSQP-APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGG 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB9 --KRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKD :::::.::: :.::::::::.:::::::::::::..:::.:::::::::::::::::: NP_705 EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKD 160 170 180 190 200 210 220 pF1KB9 SKMKSKEAL .. NP_705 HRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 220 230 240 250 260 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 469 init1: 360 opt: 456 Z-score: 339.7 bits: 70.2 E(85289): 3.5e-12 Smith-Waterman score: 456; 40.1% identity (56.5% similar) in 232 aa overlap (1-216:3-223) 10 20 30 40 50 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSL :::.. :: : . :..: . . ..: .. .. : :: .: : : NP_076 MAMSSFLINSNYVD-PKFPPCEEYSQSDYLPSD--HSPGYYAGGQRRESSFQPEAG---- 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 HGVDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEI : : . . . :: . : : : ::. . : : :. NP_076 FGRRAACTVQRYA---ACRDPGPPPPPPPPPPPPP-PPGLSPRAPAPPPAGALLPEPGQR 60 70 80 90 100 120 130 140 150 160 pF1KB9 KEEQAQTGQPAGLSQ-P--PAP-------PQIYPWMTKLHMS----HETDG--KRSRTSY : ... : .: : :.: : .:::: :.:.: . . : :::::.: NP_076 CEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAY 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 TRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL :: :.::::::::.:::::::::.:::. :::.:::::::::::::::::: :. NP_076 TRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIR 170 180 190 200 210 220 NP_076 SGGAAGSAGGPPGRPNGGPRAL 230 240 250 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 431 init1: 365 opt: 457 Z-score: 339.1 bits: 70.4 E(85289): 3.8e-12 Smith-Waterman score: 467; 42.3% identity (58.1% similar) in 227 aa overlap (2-216:71-276) 10 20 30 pF1KB9 MSSYVANSFYKQSPNIPAYNMQTCGNYGSAS .:: : .. : :: . .:.:. NP_002 GYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTARE-PAYPAAALYP--AHGAAD 50 60 70 80 90 40 50 60 70 80 pF1KB9 EVQASRYCYGGLDLSITFP--PPA----PSNSLHGVDMAANPRAHPDRPACSAAAAPGHA . : :. : ::: :...::. . : .: :.: : NP_002 TAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQPR----AVPPAA 100 110 120 130 140 150 90 100 110 120 130 140 pF1KB9 PGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMT : : :::: .::. . .: :: ... : ::. : .:::: NP_002 PRRCEAAPATPGVPAGGSA-PACPLLLADKS-----------PLGLKGKE--PVVYPWMK 160 170 180 190 150 160 170 180 190 pF1KB9 KLHMS------HETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQI :.:.: . . :::::.::: :.::::::::::::::::::::::..:::.:::. NP_002 KIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQV 200 210 220 230 240 250 200 210 220 pF1KB9 KIWFQNRRMKWKKDSKMKSKEAL :::::::::::::: :. NP_002 KIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPHPHPSTSTPVPSS 260 270 280 290 300 310 >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 430 init1: 347 opt: 422 Z-score: 316.6 bits: 65.8 E(85289): 6.8e-11 Smith-Waterman score: 429; 45.9% identity (64.7% similar) in 170 aa overlap (67-222:45-213) 40 50 60 70 80 90 pF1KB9 RYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLN- : :. ... : . : .::: . XP_005 ASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDY 20 30 40 50 60 70 100 110 120 130 140 pF1KB9 ---PGMYSQKAARPAL---EERAKSSGEI-KEEQAQTGQPAGLS--QPPAPPQIYPWMTK :..: .: . :: .:. : : . :: . : . : . : .:::: . XP_005 GPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTP-VYPWMQR 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB9 LHMSHETD----GKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIW .. . .. :.:.: .::::::::::::::.:::::::::::::. :::.::::::: XP_005 MNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIW 140 150 160 170 180 190 210 220 pF1KB9 FQNRRMKWKKDSKMKSKEAL ::::::::::.::. : : XP_005 FQNRRMKWKKESKLLSASQLSAEEEEEKQAE 200 210 220 >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 430 init1: 347 opt: 422 Z-score: 316.6 bits: 65.8 E(85289): 6.8e-11 Smith-Waterman score: 429; 45.9% identity (64.7% similar) in 170 aa overlap (67-222:45-213) 40 50 60 70 80 90 pF1KB9 RYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLN- : :. ... : . : .::: . NP_061 ASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDY 20 30 40 50 60 70 100 110 120 130 140 pF1KB9 ---PGMYSQKAARPAL---EERAKSSGEI-KEEQAQTGQPAGLS--QPPAPPQIYPWMTK :..: .: . :: .:. : : . :: . : . : . : .:::: . NP_061 GPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTP-VYPWMQR 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB9 LHMSHETD----GKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIW .. . .. :.:.: .::::::::::::::.:::::::::::::. :::.::::::: NP_061 MNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIW 140 150 160 170 180 190 210 220 pF1KB9 FQNRRMKWKKDSKMKSKEAL ::::::::::.::. : : NP_061 FQNRRMKWKKESKLLSASQLSAEEEEEKQAE 200 210 220 222 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:20:05 2016 done: Fri Nov 4 18:20:06 2016 Total Scan time: 6.570 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]