FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9690, 226 aa 1>>>pF1KB9690 226 - 226 aa - 226 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1488+/-0.0003; mu= 6.3389+/- 0.019 mean_var=270.5245+/-55.335, 0's: 0 Z-trim(126.5): 26 B-trim: 874 in 1/61 Lambda= 0.077978 statistics sampled from 52660 (52686) to 52660 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.866), E-opt: 0.2 (0.618), width: 16 Scan time: 8.180 The best scores are: opt bits E(85289) NP_006548 (OMIM: 604935) doublesex- and mab-3-rela ( 226) 1607 192.3 5.8e-49 NP_001124337 (OMIM: 604935) doublesex- and mab-3-r ( 226) 1607 192.3 5.8e-49 XP_016869705 (OMIM: 604935) PREDICTED: doublesex- ( 226) 1607 192.3 5.8e-49 XP_016869703 (OMIM: 604935) PREDICTED: doublesex- ( 561) 1495 180.1 6.4e-45 XP_016869704 (OMIM: 604935) PREDICTED: doublesex- ( 561) 1495 180.1 6.4e-45 XP_011515989 (OMIM: 604935) PREDICTED: doublesex- ( 561) 1495 180.1 6.4e-45 NP_870987 (OMIM: 604935) doublesex- and mab-3-rela ( 561) 1495 180.1 6.4e-45 XP_016869702 (OMIM: 604935) PREDICTED: doublesex- ( 561) 1495 180.1 6.4e-45 XP_011515992 (OMIM: 604935) PREDICTED: doublesex- ( 561) 1495 180.1 6.4e-45 XP_016869864 (OMIM: 602424) PREDICTED: doublesex- ( 215) 416 58.3 1.2e-08 NP_068770 (OMIM: 602424) doublesex- and mab-3-rela ( 373) 416 58.5 1.7e-08 XP_006716795 (OMIM: 602424) PREDICTED: doublesex- ( 374) 416 58.5 1.7e-08 NP_071443 (OMIM: 614803) doublesex- and mab-3-rela ( 504) 401 57.0 6.7e-08 XP_011540239 (OMIM: 614804) PREDICTED: doublesex- ( 542) 374 54.0 5.7e-07 NP_115486 (OMIM: 614804) doublesex- and mab-3-rela ( 542) 374 54.0 5.7e-07 NP_067063 (OMIM: 614754) doublesex- and mab-3-rela ( 472) 356 51.9 2.1e-06 XP_016882613 (OMIM: 614806) PREDICTED: doublesex- ( 421) 339 49.9 7.5e-06 XP_011525518 (OMIM: 614806) PREDICTED: doublesex- ( 228) 334 49.1 7.5e-06 NP_001035373 (OMIM: 614806) doublesex- and mab-3-r ( 367) 334 49.3 1e-05 XP_016882618 (OMIM: 614806) PREDICTED: doublesex- ( 372) 334 49.3 1e-05 XP_016882616 (OMIM: 614806) PREDICTED: doublesex- ( 418) 334 49.4 1.1e-05 XP_016882615 (OMIM: 614806) PREDICTED: doublesex- ( 418) 334 49.4 1.1e-05 XP_016882617 (OMIM: 614806) PREDICTED: doublesex- ( 418) 334 49.4 1.1e-05 XP_016882614 (OMIM: 614806) PREDICTED: doublesex- ( 418) 334 49.4 1.1e-05 XP_016882612 (OMIM: 614806) PREDICTED: doublesex- ( 423) 334 49.4 1.1e-05 NP_149056 (OMIM: 614805) doublesex- and mab-3-rela ( 342) 268 41.9 0.0017 >>NP_006548 (OMIM: 604935) doublesex- and mab-3-related (226 aa) initn: 1607 init1: 1607 opt: 1607 Z-score: 1000.1 bits: 192.3 E(85289): 5.8e-49 Smith-Waterman score: 1607; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL :::::::::::::::::::::::::::::::::::::::::::::: NP_006 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL 190 200 210 220 >>NP_001124337 (OMIM: 604935) doublesex- and mab-3-relat (226 aa) initn: 1607 init1: 1607 opt: 1607 Z-score: 1000.1 bits: 192.3 E(85289): 5.8e-49 Smith-Waterman score: 1607; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL :::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL 190 200 210 220 >>XP_016869705 (OMIM: 604935) PREDICTED: doublesex- and (226 aa) initn: 1607 init1: 1607 opt: 1607 Z-score: 1000.1 bits: 192.3 E(85289): 5.8e-49 Smith-Waterman score: 1607; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL :::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL 190 200 210 220 >>XP_016869703 (OMIM: 604935) PREDICTED: doublesex- and (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: XP_016 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>XP_016869704 (OMIM: 604935) PREDICTED: doublesex- and (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: XP_016 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>XP_011515989 (OMIM: 604935) PREDICTED: doublesex- and (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: XP_011 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>NP_870987 (OMIM: 604935) doublesex- and mab-3-related (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_870 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_870 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_870 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: NP_870 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>XP_016869702 (OMIM: 604935) PREDICTED: doublesex- and (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: XP_016 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>XP_011515992 (OMIM: 604935) PREDICTED: doublesex- and (561 aa) initn: 1495 init1: 1495 opt: 1495 Z-score: 927.5 bits: 180.1 E(85289): 6.4e-45 Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB9 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 130 140 150 160 170 180 190 200 210 220 pF1KB9 SGKQNNFERKAVYQRQVRAPSLLAKSILEVLLGLFYSYYVYIMNHL ::::::::::::::::::::::::::::: XP_011 SGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAF 190 200 210 220 230 240 >>XP_016869864 (OMIM: 602424) PREDICTED: doublesex- and (215 aa) initn: 433 init1: 371 opt: 416 Z-score: 276.2 bits: 58.3 E(85289): 1.2e-08 Smith-Waterman score: 416; 50.4% identity (65.6% similar) in 131 aa overlap (56-181:4-134) 30 40 50 60 70 80 pF1KB9 VCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQ :: . . :: .::.: : . : . XP_016 MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGK 10 20 30 90 100 110 120 130 140 pF1KB9 PRPPLAPQASPAGTGPRERCTPAGGGAEP-----RKLSRTPKCARCRNHGVVSCLKGHKR :. :: ...: : .:.:: .: : :::::::::: .: :::::: XP_016 ASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 FCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAP :: :::::: .: :..::::::::::::::::: :.. :.: XP_016 FCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNG 100 110 120 130 140 150 210 220 pF1KB9 SLLAKSILEVLLGLFYSYYVYIMNHL XP_016 SNPCLMTECSGTSQPPPASVPTTAASDEEHGEPPCNELPVQDAFLLPASLLPGPERAPVL 160 170 180 190 200 210 226 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:21:04 2016 done: Fri Nov 4 18:21:05 2016 Total Scan time: 8.180 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]